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        Controllable synthesis of plate BiOBr loaded plate Bi2O2CO3 with exposed {001} facets for ciprofloxacin photo-degradation

        Xiaoxiao Su,Dongfang Wu 한국공업화학회 2018 Journal of Industrial and Engineering Chemistry Vol.64 No.-

        Combination of semiconductors is one of the most efficient ways to improve photocatalytic activities. Plate BiOBr loaded plate Bi2O2CO3 facet is fabricated via one-step hydrothermal process, where urea acts not only as carbon source but as capping agent. As-prepared Bi2O2CO3/BiOBr is of an irregular multi-plate shape, a desirable structure for improved photocatalytic properties. Bi2O2CO3/BiOBr nanoplates with exposed active {001} facet exhibit a ciprofloxacin degradation rate of 90% under visible-light for 4 h. The photodegradation mechanism is speculated. The high activity is attributed to the exposed {001} facet of Bi2O2CO3, formation of heterojunction, extended photoresponse range, and efficient charges carrier transfer.

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        Rapid Detection of Food-borne Listeria monocytogenes by Real-time Quantitative Loop-mediated Isothermal Amplification

        Xiaoxiao Shan,Yaoqi Zhang,Zhigang Zhang,Miaorui Chen,Yongyu Su,Yingna Yuan,M. Jahangir Alam,He Yan,Lei Shi 한국식품과학회 2012 Food Science and Biotechnology Vol.21 No.1

        The purpose of this study was to develop a real-time quantitative loop-mediated isothermal amplication (LAMP) method for the rapid, sensitive, and convenient detection of Listeria monocytogenes in food. The LAMP method could amplify the hlyA gene of L. monocytogenes successfully at 63oC with a loopamp real-time turbidimeter. The detection limits of the LAMP for hlyA gene were 6colony forming units (CFU)/tube. A standard curve was generated for L. monocytogenes LAMP by plotting the graph based different log CFU values of L. monocytogenes and time of positivity through real-time monitoring of the amplication. Then, the LAMP method was employed to test 94 retail food samples effectively. Sensitivity in detection of L. monocytogenes by the LAMP was higher than that of PCR and none of the conventional methodpositive samples was missed by the LAMP method.

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        Identification of Plasma Biomarkers in Drug-Naïve Schizophrenia Using Targeted Metabolomics

        Qiao Su,Fuyou Bi,Shu Yang,Huiming Yan,Xiaoxiao Sun,Jiayue Wang,Yuying Qiu,Meijuan Li,Shen Li,Jie Li 대한신경정신의학회 2023 PSYCHIATRY INVESTIGATION Vol.20 No.9

        Objective Schizophrenia (SCZ) is a severe psychiatric disorder with unknown etiology and lacking specific biomarkers. Herein, we aimed to explore plasma biomarkers relevant to SCZ using targeted metabolomics. Methods Sixty drug-naïve SCZ patients and 36 healthy controls were recruited. Psychotic symptoms were assessed using the Positive and Negative Syndrome Scale. We analyzed the levels of 271 metabolites in plasma samples from all subjects using targeted metabolomics, and identified metabolites that differed significantly between the two groups. Then we evaluated the diagnostic power of the metabolites based on receiver operating characteristic curves, and explored metabolites associated with the psychotic symptoms in SCZ patients. Results Twenty-six metabolites showed significant differences between SCZ patients and healthy controls. Among them, 12 metabolites were phosphatidylcholines and cortisol, ceramide (d18:1/22:0), acetylcarnitine, and γ-aminobutyric acid, which could significantly distinguish SCZ from healthy controls with the area under the curve (AUC) above 0.7. Further, a panel consisting of the above 4 metabolites had an excellent performance with an AUC of 0.867. In SCZ patients, phosphatidylcholines were positively related with positive symptoms, and cholic acid was positively associated with negative symptoms. Conclusion Our study provides insights into the metabolite alterations associated with SCZ and potential biomarkers for its diagnosis and symptom severity assessment.

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        Synergistic photocatalysis of bimetal mixed ZIFs in enhancing degradation of organic pollutants: Experimental and computational studies

        Weihao Zhu,Yuanfeng Wu,Guiyun Yi,Xiaoxiao Su,Qiangsheng Pan,Shengbin Shi,Olayinka Oderinde,Guomin Xiao,Chuanxiang Zhang,Yulong Zhang 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.119 No.-

        The present work is aimed at studying the synergistic catalysis of the bimetal ZIFs containing Co and Znmetal ions prepared by solvothermal method in the degradation of organic pollutants under ambientconditions. The bimetal mixed ZIFs were further characterized by some techniques such as XRD, SEM,TG-DTG, XPS, UV–vis, ESR, and N2-adsorption. Interestingly, the sample prepared with equal metal ions(1Zn:1Co) showed the highest catalytic performance for methylene blue (MB) degradation (94.10 %). Thismay be associated with the interaction between cobalt and zinc within the adjacent lattice, which makethe MB molecule to be easily adsorbed and degraded on empty electron orbit. Furthermore, the highestdegradation of MB was achieved with 98.83 % under the optimized conditions (catalyst weight of 50 mg,pH of 5, 3 h, 30 C). Besides, the various substrates such as methyl orange, indole, rofloxacin, methyl blue,and tetracycline were also investigated under the same conditions. Additionally, the DFT calculationresults suggested the more orbital distribution (LUMO, HOMO) of ZIF(1Zn:1Co) can result to more electronsbeing easily captured, and generate more radicals via electron transfer. Finally, the photocatalyticdegradation of MB is consistent with the first law of kinetics, and the activation energy is 26.797 KJ/molin the presence of ZIF(1Zn:1Co).

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