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Xiaomin Zhang,Jin Zhu,Xiaoqing Liu 한국고분자학회 2012 Macromolecular Research Vol.20 No.7
Regenerated cellulose/poly(vinyl alcohol) (PVA) blend films in ionic liquid 1-allyl-3-methylimidazolium chloride (AMIMCl) were successfully prepared by coagulating with water. The structures and properties were characterized by scanning electron microscope (SEM), X-ray diffraction (XRD), and differential scanning calorimetry (DSC). SEM images indicated that there was good compatibility between cellulose and PVA. The XRD results showed that the crystallinity of cellulose was significantly decreased from 42.8% up to 29.4% with increasing PVA content. The blend film with a 10 wt% PVA demonstrated the best mechanical performance. Its tensile strength and modulus showed 97 and 5,100 MPa, respectively compared with 69 and 3,400 MPa of neat cellulose film. The elongation also increased 50%. In addition, the transparency of the blend lms was still maintained well, and the shrinkage of the regenerated cellulose film was greatly improved with incorporation of PVA. The possible mechanism of forming cellulose/PVA blend films was proposed in the process of regeneration and dissolution.
Zhang, Jinglan,Shi, Xiaomin,Li, Yehua,Kim, Beom-Jun,Jia, Junling,Huang, Zhiwei,Yang, Tao,Fu, Xiaoyong,Jung, Sung Yun,Wang, Yi,Zhang, Pumin,Kim, Seong-Tae,Pan, Xuewen,Qin, Jun Elsevier 2008 Molecular cell Vol.31 No.1
<P><B>Summary</B></P><P>Sister chromatid cohesion is normally established in S phase in a process that depends on the cohesion establishment factor Eco1, a conserved acetyltransferase. However, due to the lack of known in vivo substrates, how Eco1 regulates cohesion is not understood. Here we report that yeast Eco1 and its human ortholog, ESCO1, both acetylate Smc3, a component of the cohesin complex that physically holds the sister chromatid together, at two conserved lysine residues. Mutating these lysine residues to a nonacetylatable form leads to increased loss of sister chromatid cohesion and genome instability in both yeast and human. In addition, we clarified that the acetyltransferase activity of Eco1 is essential for its function. Our study thus identified a molecular target for the acetyltransferase Eco1 and revealed that Smc3 acetylation is a conserved mechanism in regulating sister chromatid cohesion.</P>
Novel Schemes to Optimize Sampling Rate for Compressed Sensing
YiFan Zhang,Xuan Fu,Qixun Zhang,Zhiyong Feng,Xiaomin Liu 한국통신학회 2015 Journal of communications and networks Vol.17 No.5
The fast and accurate spectrum sensing over an ultra- wide bandwidth is a big challenge for the radio environment cogni- tion. Considering sparse signal feature, two novel compressed sens- ing schemes are proposed, which can reduce compressed sampling rate in contrast to the traditional scheme. One algorithm is dynam- ically adjusting compression ratio based on modulation recogni- tion and identification of symbol rate, which can reduce compres- sion ratio. Furthermore, without priori information of the modu- lation and symbol rate, another improved algorithm is proposed with the application potential in practice, which does not need to reconstruct the signals. The improved algorithm is divided into two stages, which are the approaching stage and the monitoring stage. The overall sampling rate can be dramatically reduced with- out the performance deterioration of the spectrum detection com- pared to the conventional static compressed sampling rate algo- rithm. Numerous results show that the proposed compressed sens- ing technique can reduce sampling rate by 35%, with an acceptable detection probability over 0.9.
Pilot Symbol Assisted Weighted Data Fusion Scheme for Uplink Base-Station Cooperation System
( Zhe Zhang ),( Jing Yang ),( Jiankang Zhang ),( Xiaomin Mu ) 한국인터넷정보학회 2015 KSII Transactions on Internet and Information Syst Vol.9 No.2
Base Station Cooperation (BSC) has been a promising technique for combating the Inter-Cell Interference (ICI) by exchanging information through a high-speed optical fiber back-haul to increase the diversity gain. In this paper, we propose a novel pilot symbol assisted data fusion scheme for distributed Uplink BSC (UBSC) based on Differential Evolution (DE) algorithm. Furthermore, the proposed scheme exploits the pre-defined pilot symbols as the sample of transmitted symbols to constitute a sub-optimal Weight Calculation (WC) model. To circumvent the non-linear programming problem of the proposed sub-optimal model, DE algorithm is employed for searching the proper fusion weights. Compared with the existing equal weights based soft combining scheme, the proposed scheme can adaptively adjust the fusion weights according to the accuracy of cooperative information, which remains the relatively low computational complexity and back-haul traffic. Performance analysis and simulation results show that, the proposed scheme can significantly improve the system performance with the pilot settings of the existing standards.
Xiaomin Jin,Yuanan Liu,Wenhao Fan,Fan Wu,Hongguang Zhang 보안공학연구지원센터 2015 International Journal of Future Generation Communi Vol.8 No.2
Nowadays, many network devices have more than one network interface. Meanwhile, many protocols have been proposed to utilize multiple paths simultaneously. MPTCP (Multipath TCP) is a transport layer protocol that transfers data by multiple paths simultaneously, which is designed to improve the throughput and increase robustness of end to end transmission. However, when we use MPTCP, we find that MPTCP can not improve the throughput but even reduce the throughput in some cases. In this paper, we study this issue. Firstly, we study the effects of path characteristics for throughput of MPTCP, and find that path characteristics especially those bad paths have a great impact on the performance of MPTCP. Secondly, we analyze the reasons why the bad path characteristics have a serious impact on throughput of MPTCP, and propose a path selection method based on throughput prediction model and available bandwidth to improve the throughput. Finally, we validate our path selection method by simulations, and the results show that our method can improve the throughput of MPTCP.
Isoforms of wild type proteins often appear as low molecular weight bands on SDS-PAGE.
Zhang, Ju,Lou, Xiaomin,Shen, Haihong,Zellmer, Lucas,Sun, Yuan,Liu, Siqi,Xu, Ningzhi,Liao, D Joshua Wiley 2014 Biotechnology Journal Vol.9 No.8
<P>Immunoblotting, after polyacrylamide gel electrophoresis with sodium dodecyl sulfate (SDS-PAGE), is a technique commonly used to detect specific proteins. SDS-PAGE often results in the visualization of protein band(s) in addition to the one expected based on the theoretical molecular mass (TMM) of the protein of interest. To determine the likelihood of additional band(s) being nonspecific, we used liquid chromatography - mass spectrometry to identify proteins that were extracted from bands with the apparent molecular mass (MM) of 40 and 26 kD, originating from protein extracts derived from non-malignant HEK293 and cancerous MDA-MB231 (MB231) cells separated using SDS-PAGE. In total, approximately 57% and 21% of the MS/MS spectra were annotated as peptides in the two cell samples, respectively. Moreover, approximately 24% and 36.2% of the identified proteins from HEK293 and MB231 cells matched their TMMs. Of the identified proteins, 8% from HEK293 and 26% from MB231 had apparent MMs that were larger than predicted, and 67% from HEK293 and 37% from MB231 exhibited smaller MM values than predicted. These revelations suggest that interpretation of the positive bands of immunoblots should be conducted with caution. This study also shows that protein identification performed by mass spectrometry on bands excised from SDS-PAGE gels could make valuable contributions to the identification of cancer biomarkers, and to cancer-therapy studies.</P>
Wenkai Zhang,Yanshan Zhan,Xiuxiu Gao,Runming Li,Weiwei Zhu,Hao Xu,Baoying Liu,Xiaomin Fang,Yuanqing Xu,Tao Ding 한국고분자학회 2018 Macromolecular Research Vol.26 No.1
Herein, we report the effect of oxygen functionalities of graphene oxide on thermal activated polymerization and thermal properties of reactive benzoxazine nanocomposites. The numbers of oxygen moieties of graphene oxide (GO) are controlled by hydrothermal reduction. The polymerization behavior of benzoxazine monomer (BA-a) is studied by Fourier transform infrared spectroscopy, differential scanning calorimetry and rheological analysis. It is hypothesized that the GO not only exhibits accelerated effect on the polymerization of the BA-a, but also the oxygen moieties such as carboxyl groups of GO interact with the benzoxazine polymers, leading to several orders of magnitude increase in the chemoviscosity and modulus of composite system. Thermal conductivity of poly(BA-a)/GO composite increases from an initial value of ∼0.27 W/mK to 0.47 W/mK as the loading increases from 1 wt% to 6 wt% (enhancement factor up to 176%). Moreover, the nanocomposites display enhanced initial decomposition temperature and char yields as the degree of GO reduction increases.
Melatonin prevents lung injury by regulating apelin 13 to improve mitochondrial dysfunction
Lu Zhang,Fangli Liu,Xiaomin Su,Yue Li,Yining Wang,Ruonan Fang,Yingying Guo,Tongzhu Jin,Huitong Shan,Xiaoguang Zhao,Rui Yang,Hongli Shan,Haihai Liang 생화학분자생물학회 2019 Experimental and molecular medicine Vol.51 No.-
Pulmonary fibrosis is a progressive disease characterized by epithelial cell damage, fibroblast proliferation, excessive extracellular matrix (ECM) deposition, and lung tissue scarring. Melatonin, a hormone produced by the pineal gland, plays an important role in multiple physiological and pathological responses in organisms. However, the function of melatonin in the development of bleomycin-induced pulmonary injury is poorly understood. In the present study, we found that melatonin significantly decreased mortality and restored the function of the alveolar epithelium in bleomycin-treated mice. However, pulmonary function mainly depends on type II alveolar epithelial cells (AECIIs) and is linked to mitochondrial integrity. We also found that melatonin reduced the production of reactive oxygen species (ROS) and prevented apoptosis and senescence in AECIIs. Luzindole, a nonselective melatonin receptor antagonist, blocked the protective action of melatonin. Interestingly, we found that the expression of apelin 13 was significantly downregulated in vitro and in vivo and that this downregulation was reversed by melatonin. Furthermore, ML221, an apelin inhibitor, disrupted the beneficial effects of melatonin on alveolar epithelial cells. Taken together, these results suggest that melatonin alleviates lung injury through regulating apelin 13 to improve mitochondrial dysfunction in the process of bleomycin-induced pulmonary injury.