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      • Tailoring fabric geometry of plain-woven composites for simultaneously enhancing stiffness and thermal properties

        Xiao-Yi Zhou,Neng-Wei Wang,Wen Xiong,Xin Ruan,Shao-Jin Zhang 국제구조공학회 2022 Steel and Composite Structures, An International J Vol.42 No.4

        This paper proposes a numerical optimization method to design the mesoscale architecture of textile composite for simultaneously enhancing mechanical and thermal properties, which compete with each other making it difficult to design intuitively. The base cell of the periodic warp and fill yarn system is served as the design space, and optimal fibre yarn geometries are found by solving the optimization problem through the proposed method. With the help of homogenization method, analytical formulae for the effective material properties as functions of the geometry parameters of plain-woven textile composites were derived, and they are used to form the inverse homogenization method to establish the design problem. These modules are then put together to form a multiobjective optimization problem, which is formulated in such a way that the optimal design depends on the weight factors predetermined by the user based on the stiffness and thermal terms in the objective function. Numerical examples illustrate that the developed method can achieve reasonable designs in terms of fibre yarn paths and geometries.

      • KCI등재

        Lycorine: A Potential Broad-Spectrum Agent Against Crop Pathogenic Fungi

        ( Jin Wen Shen ),( Yuan Ruan ),( Wei Ren ),( Bing Ji Ma ),( Xiao Long Wang ),( Chun Feng Zheng ) 한국미생물 · 생명공학회 2014 Journal of microbiology and biotechnology Vol.24 No.3

        A screening test showed that lycorine exhibited significant antifungal activity against 24 pathogenic crop fungi at concentrations of 500μg/ml and 100μg/ml, respectively. Fusarium graminearum was selected for antifungal mechanism studies by observing its mycelial morphology and investigating the variations in its conductivity. In addition, the substance absorption and metabolism of F. graminearum were explored. The mechanism was revealed as being one by which lycorine destroyed the cellular membrane and further influenced substance absorption and cell metabolism.

      • KCI등재
      • Staged Improvement in Awareness of Disease for Elderly Cancer Patients in Southern China

        Li, Xing,Dong, Min,Wen, Jing-Yun,Wei, Li,Ma, Xiao-Kun,Xing, Yan-Fang,Deng, Yun,Chen, Zhan-Hong,Chen, Jie,Ruan, Dan-Yun,Lin, Ze-Xiao,Wang, Tian-Tian,Wu, Dong-Hao,Liu, Xu,Hu, Hai-Tao,Lin, Jia-Yu,Li, Zhu Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.15

        Background: In mainland China, awareness of disease of elderly cancer patients largely relies on the patients' families. We developed a staged procedure to improve their awareness of disease. Materials and Methods: Participants were 224 elderly cancer patients from 9 leading hospitals across Southern China. A questionnaire was given to the oncologists in charge of each patient to evaluate the interaction between family and patients, patient awareness of their disease and participation in medical decision-making. After first cycles of treatment, increased information of disease was given to patients with cooperation of the family. Then patient awareness of their disease and participation in medical decision-making was documented. Results: Among the 224 cancer elderly patients, 26 (11.6%) made decisions by themselves and 125 (55.8%) delegated their rights of decision-making to their family. Subordinate family members tended to play a passive role in decision-making significantly. Patients participating more in medical decision-making tended to know more about their disease. However, in contrast to the awareness of disease, patient awareness of violation of medical recommendations was reversely associated with their participation in medical decision-making. Improvement in awareness of diagnosis, stages and prognosis was achieved in about 20% elderly cancer patients. About 5% participated more actively in medical decision-making. Conclusions: Chinese elderly cancer patient awareness of disease and participation in medical decision-making is limited and relies on their family status. The staged procedure we developed to improve patient awareness of disease proved effective.

      • KCI등재

        Relationship between phase structure and electrical properties of (K0.5Na0.5)NbO3–LiTaO3 lead-free ceramics

        Hongqiang Wang,Dingshan Ruan,Ye-Jing Dai,Xiao-Wen Zhang 한국물리학회 2012 Current Applied Physics Vol.12 No.2

        Lead-free piezoelectric ceramics of (1-x)K0.5Na0.5NbO3-xLiTaO3 (KNN-LT) system have been investigated in this work. X-ray diffraction, Raman spectra measurements, DSC (Differential Scanning Calorimetric),and dielectric constant versus temperature provide direct evidence that the phase transition temperature between tetragonal and orthorhombic shift to lower temperature with the increasing of LT content. The KNN-0.05LT ceramics exhibit the highest high-field d33 up to 220 pm/V. At the same time, we also investigated the relationship between phase structure and electric properties, showing that the orthorhombic phase presents better piezoelectric temperature stabilities than the tetragonal phase. The result may provide a new way for KNN-based lead-free ceramics.

      • KCI등재

        중국 부동산 시장에 관한 연구

        이성준 ( Sung Joon Lee ),( Ruan Xiao Wen ) 한국물류학회 2011 물류학회지 Vol.21 No.4

        중국의 부동산시장은 2004년부터 2009년 동안 중국경제 성장에 기여한 기여율이 년 평균 10%를 상회하였으며, 또한 2010년에 중국 전체 GDP의 6%를 차지하는 등 중국경제 발전을 견인하는 주요요인 중 하나가 되었다. 그러나 이와 같은 중국의 급속한부동산 시장 확대는 부동산 가격의 폭등과 부동산 투기과열로 중국경제와 중국사회에 적지 않은 문제를 낳고 있다. 본고는 중국 부동산 시장 과열이 물류 및 유통산업의 원활한 발전에 방해가 되고 있어, 이에 대한 해결방안 도출하는데 연구 목적을 두고 있으며, 한국과 일본의 부동산시장 과열 방지 정책을 검토하고, 각종 중국 내 선행연구를 중심으로 연구하여 문제해결방안을 제시하고자 하였다. 연구결과 부동산 시장의 지나친 과열현상을 진정시키고 지역 간 균형 발전과 유통 및 물류산업의 발전을 원활하게 하기 위하여 첫째, 중국정부는 느슨한 금용정책을 지양하고 강력한 금융정책을 도입해야 하겠다. 즉, 부동산 시장에 진입하는 불법 자본에대한 감독 강화와, 해외에서 유입되는 핫머니(Hot money)를 방지하는 금융정책이 필요하다. 둘째, 중국정부는 부동산 시장에 매크로 제어를 강화해야 하겠다. 토지는 가장 기본적인 산업재로서 경제발전에 중요한자원이므로토지세는낮추고, 건물등부동산에 대한 세금을 높이는 이중적 세금제도가 요구된다. 셋째, 고율의 재산세 부과가 필요하다. 저율의 금리를 이용한 투기자금의 부동산 시장 진입을 막기 위해서 필요한 조치이다. 넷째, 낮은 임대료임대 주택보급정책 도입이다. 부동산 소유에 대한장기투자이익을 기대하는 부동산 투기를 사전에 방지하기 위해 임대료가 싼 임대주택을 대량 보급함으로서 서민들의 주택 이용률을 높이고 부동산 시장 안정을 꾀할 수 있겠다. With the fast development of the Chinese economy and its urbanization, the real estate industry has been one of the most important and energetic industries to push up the economic scale in China. However during the process of development, there has been an excessive rise in real estate price and it has caused many economic and social problems. This paper examined the reasons why Chinese real estate market had soaring rise and also discussed the future development of Chinese housing property industry and meanwhile, this paper proposed some possible solutions to help China cool the real estate market and eventually to devoted to the healthy development of Chinese economy. This paper also discussed the relationship between developing real estate industry and national economic growth based on the case study in Japan and Korea. This paper found that due to Chinese governmental lax supervision on finance, due to Chinese governmental monopoly policy on land, due to the speculation on the real estate market and the fact of Chinese traditional concept of house ownership meanwhile, this paper found that the further reasons including house as the vale-added investment, urbanization, income rise and ect.; all of these factors devoted to the excessive rise in house price in Chinese real estate market. Based on the factors, this paper proposed that strengthening governmental supervision, levying property tax, repressing speculation and increasing the construction of low-rent house and affordable housefor public be possible ways to stable the real estate market and devote to the healthy development of Chinese economy.

      • Efficacy of Prophylactic Entecavir for Hepatitis B Virus-Related Hepatocellular Carcinoma Receiving Transcatheter Arterial Chemoembolization

        Li, Xing,Zhong, Xiang,Chen, Zhan-Hong,Wang, Tian-Tian,Ma, Xiao-Kun,Xing, Yan-Fang,Wu, Dong-Hao,Dong, Min,Chen, Jie,Ruan, Dan-Yun,Lin, Ze-Xiao,Wen, Jing-Yun,Wei, Li,Wu, Xiang-Yuan,Lin, Qu Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.18

        Background and Aims: Hepatitis B virus (HBV) reactivation was reported to be induced by transcatheter arterial chemoembolization (TACE) in HBV-related hepatocellular carcinonma (HCC) patients with a high incidence. The effective strategy to reduce hepatitis flares due to HBV reactivation in this specific group of patients was limited to lamivudine. This retrospective study was aimed to investigate the efficacy of prophylactic entecavir in HCC patients receiving TACE. Methods: A consecutive series of 191 HBV-related HCC patients receiving TACE were analyzed including 44 patients received prophylactic entecavir. Virologic events, defined as an increase in serum HBV DNA level to more than 1 log10 copies/ml higher than nadir the level, and hepatitis flares due to HBV reactivation were the main endpoints. Results: Patients with or without prophylactic were similar in host factors and the majorities of characteristics regarding to tumor factors, HBV status, liver function and LMR. Notably, cycles of TACE were parallel between the groups. Ten (22.7%) patients receiving prophylactic entecavir reached virologic response. The patients receiving prophylactic entecavir presented significantly reduced virologic events (6.8% vs 54.4%, p=0.000) and hepatitis flares due to HBV reactivation (0.0% vs 11.6%, p=0.039) compared with patients without prophylaxis. Kaplan-Meier analysis illustrated that the patients in the entecavir group presented significantly improved virologic events free survival (p=0.000) and hepatitis flare free survival (p=0.017). Female and Eastern Cooperative Oncology Group (ECOG) performance status 2 was the only significant predictors for virological events in patients without prophylactic antiviral. Rescue antiviral therapy did not reduce the incidence of hepatitis flares due to HBV reactivation. Conclusion: Prophylactic entecavir presented promising efficacy in HBV-related cancer patients receiving TACE. Lower performance status and female gender might be the predictors for HBV reactivation in these patients.

      • SCIESCOPUSKCI등재

        Heavy concrete shielding properties for carbon therapy

        Jin-Long Wang,Jiade J Lu,Da-Jun Ding,Wen-Hua Jiang,Ya-Dong Li,Rui Qiu,Hui Zhang,Xiao-Zhong Wang,Huo-Sheng Ruan,Yan-Bing Teng,Xiao-Guang Wu,Yun Zheng,Zi-Hao Zhao,Kai-Zhong Liao,Huan-Cheng Mai,Xiao-Dong Korean Nuclear Society 2023 Nuclear Engineering and Technology Vol.55 No.6

        As medical facilities are usually built at urban areas, special concrete aggregates and evaluation methods are needed to optimize the design of concrete walls by balancing density, thickness, material composition, cost, and other factors. Carbon treatment rooms require a high radiation shielding requirement, as the neutron yield from carbon therapy is much higher than the neutron yield of protons. In this case study, the maximum carbon energy is 430 MeV/u and the maximum current is 0.27 nA from a hybrid particle therapy system. Hospital or facility construction should consider this requirement to design a special heavy concrete. In this work, magnetite is adopted as the major aggregate. Density is determined mainly by the major aggregate content of magnetite, and a heavy concrete test block was constructed for structural tests. The compressive strength is 35.7 MPa. The density ranges from 3.65 g/cm<sup>3</sup> to 4.14 g/cm<sup>3</sup>, and the iron mass content ranges from 53.78% to 60.38% from the 12 cored sample measurements. It was found that there is a linear relationship between density and iron content, and mixing impurities should be the major reason leading to the nonuniform element and density distribution. The effect of this nonuniformity on radiation shielding properties for a carbon treatment room is investigated by three groups of Monte Carlo simulations. Higher density dominates to reduce shielding thickness. However, a higher content of high-Z elements will weaken the shielding strength, especially at a lower dose rate threshold and vice versa. The weakened side effect of a high iron content on the shielding property is obvious at 2.5 µSv=h. Therefore, we should not blindly pursue high Z content in engineering. If the thickness is constrained to 2 m, then the density can be reduced to 3.3 g/cm<sup>3</sup>, which will save cost by reducing the magnetite composition with 50.44% iron content. If a higher density of 3.9 g/cm<sup>3</sup> with 57.65% iron content is selected for construction, then the thickness of the wall can be reduced to 174.2 cm, which will save space for equipment installation.

      • Hepatitis B Virus DNA Negativity Acts as a Favorable Prognostic Factor in Hepatocellular Carcinoma Patients

        Li, Xing,Zhong, Xiang,Chen, Zhan-Hong,Xing, Yan-Fang,Wu, Dong-Hao,Chen, Jie,Ma, Xiao-Kun,Lin, Qu,Wen, Jing-Yun,Wei, Li,Wang, Tian-Tian,Ruan, Dan-Yun,Lin, Ze-Xiao,Wu, Xiang-Yuan,Dong, Min Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.22

        Background: This retrospective study was aimed to investigate the efficacy of prophylactic agents in hepatocellular carcinoma (HCC) patients receiving TACE and compare the difference between lamivudine and entecavir. Materials and Methods: A consecutive series of 203 HBV-related HCC patients receiving TACE were analyzed including 91 patients given prophylactic agents. Virologic events, defined as an increase in serum HBV DNA level to more than 1 log10 IU/ml higher than the nadir level, hepatitis flares due to HBV reactivation and progression free survival (PFS) were the main endpoints. Results: Some 48 (69.6%) reached virologic response. Prophylaxis significantly reduced virologic events (8.8% vs 58.0%, p=0.000) and hepatitis flares (1.1% vs 13.4%, p=0.001). Patients presenting undetectable HBV DNA levels displayed a significantly improved PFS as compared to those who never achieved undetectable HBV DNA. Prophylaxis and e-antigen positivity were the only significant variables associated with virologic events. In addition, prophylaxis was the only independent protective factor for hepatitis flares. Liver cirrhosis, more cycles of TACE, HBV DNA negativity, a lower Cancer of the Liver Italian Program score, non-metastasis and no hepatitis flares were protective factors for PFS. Prophylactic lamivudine demonstrated similar efficacy as entecavir. Conclusions: Prophylactic agents are efficacious for prevention of HBV reactivation in HCC patients receiving TACE. Achievement of undetectable HBV DNA levels displayed a significant capability in improving PFS. Moreover, persistent tumor residual lesions, positive HBV DNA and hepatitis B flares might be causes of tumor progression in these patients.

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