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서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1994)
김재홍,안진균,정성재,김영태,김중환,김시영,이석종,이홍렬,서호석,김경훈,권혁진,정우권,고우석,이용석,안필수,오준규,오용섭 대한화학요법학회 1996 대한화학요법학회지 Vol.14 No.1
Background : In recent years gonorrhoea has been panendemic and remains one of the most common Sexually Transmitted Diseases in the world, especially in developing countries. Objective & Method : For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria Gonorrhoeae(PPNG), Ive have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results : In 1994, 168 strains of N. gonorrhoeae were isolated, among which 109 (64,9% ) were PPNG. Conclustion : Our results suggests that the prevalence of PPNG in Seoul is still increasing.
腸內棲息菌에 對한 硏究 : 變形菌(Proteus)에 關한 硏究
石鐘聲,金漢壽,張友鉉,李承薰 現代醫學社 1969 現代醫學 Vol.10 No.2
The proteus group are known to be widely distributed in nature and also constitute one of the important micro-flora, of human intestines. The identification of the Proteus and further differentiation into 5 species are made chiefly by their biochemical activities, which are conventionally studied with the cultures grown at 37℃. Since it is known that the metabolic activities of bacteria are influenced by the physicochemical natures of environment, it is conceivable that results of bacterial identification and differentiation based on their biochemical reactions might be different when the culture conditions differ. Thus, 100 strains of the proteus isolated from various clinical specimens were grown aerobically at 37℃ and 22℃ and the patterns of their 1, biochemical activities under the different cultural conditions were studied. The results might be summarized as follows: 1) By the biochemical activities with the cultures grown at 37℃, 100 proteus strains were differentiated into 4 species; P. rettgeri 4, P. vulgaris 14, P. mirabilis 36, and P. morganii 46. 2) If the differentiation into the species was made by the biochemical activities with the cultures grown at 22℃, the 100 strains might be classified into, P. rettgeri 41, P. vulgaris 20, P. mirabilis 34, and P. morganii 5. 3) Regardless the difference of the culture temperatures, 47 strains among the 100 strains were identified into the same species of proteus; P. rettgeri 2, P. vulgaris 7, P. mirabilis 33, and P. morganii 5. 4) Biochemically the proteus strains appeared to be more active at 37℃ than at 22℃. 5) The distribution of the 100 strains among the clinical specimens were stool or recta swat 68, pus or discharge 14, urine 10 and miscelleneous specimen 8.
禹榮均,崔錫源,卞相國 공주대학교 사범대학 과학교육연구소 1992 과학교육연구 Vol.23 No.1
Most of the fluorite ore deposits in Kumsan district occur in the Chinsan area. Specifically, these are the Okgye, Hyongyang, Ilyang, Manak fluorite ore deposits. Field survey and fluid inclusion study were undertaken to illustrate the characters and origin of the fluorite ore deposits in Chinsan area. The results of this study are as follows; Gology of the Chinsan area is composed of Majonri Formation and Changri Fomation which belong to Okchon Group and Jurassic biotite granite and Cretaceous pink feldspar granite and quartz porphyry. The wall rock of fluorite ore deposits in Chinsan area are chiefly limestone in Majonri Formation and partly limestone in Changri Formation. The relevent igneous rocks of the fluorite ore deposits are chiefly quartz porphyry, but some are biotite granite or pinkfeldspar granite. The fluorite ore deposits in this area are chiefly contact metasomatic deposits which were formed while limestones were intruded by quartz porphyry, biotite granite and pink feldspar granite. The filling degrees of fluid inclusions in fluorite ranges 84∼95% in Okgye, 85∼95% in Hyongyang, 85∼91% in Ilyang, 92∼96% in Manak ore deposits. The salinity (NaCl equivalent weight percent) ranges 0.1∼1.5wt.% in Hyongyang. 0.3∼2.8wt.% in Ilyang. 0∼1.5wt.% in Manak ore deposits. The homogenization temperature of fluorite ore deposits in Chinsan area ranges 97.6∼191.6C in Okgye, 99∼168.4C in Hyongyang. 100∼214C in Ilyang, 122∼248.6C in Okgye, 99∼168.4C in Hyongyang, 100∼214C in Ilyang, 122∼248.6C in Manak ore deposits. These data indicate that Chinsan Fluorite ore deposits belong to the epithemal or mesothemal deposits same as the other fluorite ore deposits in Korea.
비호지킨 림프종환자에서 proMACE-cytaBOM 복합항암화학요법의 유효성에 대한 제 2상 임상시험
김성우,안명주,박석규,이영렬,정태준,최일영,김인순 한양대학교 의과대학 2000 한양의대 학술지 Vol.20 No.1
Aggressive non-Hodgkin's lymphoma by REAL classification is a heterogenous group of disease. With recent advances in combination chemotherapy, the long-term survival is improved to 40-65%. We investigated twenty-one aggressive non-Hodgkin's lymphoma patients treated with pro-MACE-cytaBOM (prednisone, adriamycin, cyclophosphamide, etoposide, cytosine arabinoside, bleomycin, vincristine and methotrexated) to determine the efficacy and toxicites. There were seven patients older than 60 years. Histologic types by REAL classification were as follows : diffuse large B cell (12/21), peripheral T cell (6/21), anaplastic large cell (2/21) and angiocentric T cell (1/21). Most of patients were classified in Stage Ⅱ-Ⅳ (20/21). According to IPI (international prognostic index) score, seven patients were included in low risk, five were low-intermediate risk, three were high-intermediated risk and six were high risk group. seventeen complete responses (85%) and two partial responses (10%) were achieved. The overall response rate was 95%. The mena disease free survival was 30 months, the mean overall survival was 29 months (range:21-36), and the median overall survival was not reached. WHO grade Ⅲ/Ⅳ neutropenia or thrombocytopenia was observed in 16.7% and 2.8%, respectively. There was no treatment-related death. These results suggest that proMACE-cytaBOM combination chemotherapy is very effective and has low toxicity in the treatment of aggressive non-Hodgkin's lymphoma even treated in elderly patients.
Steepest Descent Method에 의한 複合材를 利用한 Multi-ringed Flywheel의 最適設計
洪錫雨 충남대학교 공업교육연구소 1981 論文集 Vol.4 No.2
效果的인 에너지 貯藏裝置인 Flywheel에 單位 體積當 貯藏되는 運動에너지를 最大로 하기 위하여, 應力과 設計變數에 대한 制限條件을 주고 最適設計의 方法을 Steepest Descent Method로 하여 複合材로 製作된 Multi-ringed Flywheel을 最適設計하였으며, 이를 遂行하는 Computational Algorithm을 提示하였다. 數値例로써 Glass/Epoxy 複合材를 선택하였다.