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타이포이드 백신이 뇌하수체-부신계에 미치는 효과 : 특히 순환 백혈구수에 대하여 Paricularly on the Circulating Leukocyte Counts
박종근 現代醫學社 1969 現代醫學 Vol.10 No.1
The author, using rabbits, observed the relationship between the changes of leukocyte counts" produced by tpp1ioid vaccine and, the pituitary-adrenal system. The following results were obtained: 1. Adminitsration of typhoid vaccine in the hypophysectomizedand bilaterally adrenalecto mined 'rabbits showed different response to this substance in the circulating leukocyte counts from that of the normal rabbits. 2. In the hypohysectcraized end bilaterally adrenalectcreired rabbits injected with typhoid vaccine the pseudoeosinophilia was slightly suppreessed. 3. In the hypophysectomised end bilaterally adrenalectcmised rabbits there was a weekened response to pseudoeosinophilia-inducing plasma factor after typhoid vaccination. 4. Also in the hypophysectonused and bilaterally adrenalectom zed rabbits there were no product ye impairment of pseudoeaosinophilia-inducing plasma factor in response to typhoid vaccine. 5. it was postulated that the pituitary-adrenal system and the other leukocyte regulating systems are involved in the mechanism of'leukocytosis after typhoid vaccine.