Job shop에서 지체작업수 성과를 고려한 작업배정 규칙

손영진,우종선,문석환 한국의사결정학회 2001 경영과학연구 Vol.10 No.-

Scheduling techniques and dispatching rules are widely studied because of their simulation-based analysis of dispatching rules for scheduling in dynamic job shops taking into account of utilization on the shop floor and due-date tightness. This research proposed new dispatching rules for a job shop that are expected to minimizes the proportion of tardy jobs. With respect to the proportion of tardy jobs objectives, the relative performance of the proposed dispatching rules were evaluated against that of the well-known ones.

Cisplatin 내성 난소암 세포주의 클론에서 DNA M ismatch Repair 유전자의 변이와 Taxol,Topotecan의 민감도

손우석,김흥기 關東大學校醫科大學醫科學硏究所 1998 關東醫大學術誌 Vol.2 No.1

한 대학 신입생의 우울수준과 관련변인에 관한 연구

이명학,남해성,손석준,이정애,김병우 대한보건협회 1994 대한보건연구 Vol.20 No.2

1994년도 한 대학 1년생을 대상으로 8개항목의 생활만족지수(LSI-W) 그리고 20개항목의 우울지수(CES-D) 및 관련변인들을 조사하여 각각의 점수와 우울증의 유병률을 계산하고 서로간의 관련성을 조사하여 다음과 같은 결과를 얻었다. 1. 생활만족지수의 평균점수는 9.98이었고 비흡연군, 비음주군, 운동을 하는 군에서 평균점수가 유의하게 높았다(p<0.01). 2. 우울지수의 평균점수는 17.2였고 여학생에서 남학생보다 유의하게 높았고, 우울증의 유병률은 19.8%이었고 여학생에서 남학생보다 유의하게 높았다(p<0.01). 3. 우울증세 고위험군과 저위험군에 있어서 건강에 대한 본인의 생각과 본인이 인지하는 체중에서 차이가 있었으며, 생활만족지수, 가족수, 체중, 신장에서 유의한 차이를 보였다(p<0.05). 4. 우울지수와 생활만족지수, 연령, 종교활동기간, 신장, 체중등과는 음의 상관을 나타내고(p<0.01), 가족수, 수면시간, 경제수준과는 양의 상관을 보였다(p<0.01). 5. CES-D에 영향을 미치는 변수를 알아보기 위한 단계적 로지스틱 회귀분석에서 생활만족도, 성별, 건강에 대한 본인의 생각, 본인이 인지하는 체중, 흡연, 음주가 CES-D에 의한 우울증 발현에 있어서의 유의한 요인으로 나타났다(p<0.05). The questionnaire survey using the Center for Epidemiological Studies-Depression Scale(CES-D) and 8-items Life Satisfaction Index Well-being(LSI-W) and other variables was conducted to determine the prevalence of depression and to identify the correlation among CES-D and related factors. Study population was the whole freshman group newly enrolled in a university. The results were as follows; 1. Mean score of LSI-W was 9.98 and that score was higher in non-smokers, non-drinkers and exercise group (p<0.01). 2. Mean score of CES-D was 17.2 and the prevalence of depression was 19.8%. And those were significantly higher in female than in male(p<0.01). 3. Perceived health status, perceived weight, LSI-W, family size, weight and height were significant variables between high and low risk group of depression(p<0.05). 4. CES-D score was negatively correlated with LSI-W, age, duration of religious life, height, weight and po-sitively correlated with family size, sleeping time and economic status(p<0.01). 5. In the regression analysis significant predictors of the depression were sex, preceived health status, weight, smoking and drinking(p<0.05).

Equisetum arvense L.이 고혈당 쥐의 혈중 포도당 농도에 미치는 영향

이현자,김석환,손기호,강우규,최종원 慶星大學校 環境問題硏究所 1992 環境硏報 Vol.2 No.1

The effect of methanol extract of Equisetum arvense L.(EM) on blood glucose level in streptozotocin-induced diabetic rat and acute toxicity of EM were investigated. Male Sprague-Dawley rats(200∼250g), with free access to commercial rat chow and water, were divided into four groups: Group 1 served as control; Group 2 received STZ only: Group 3 received EM only; Group 4 received pretreatment with EM followed by STZ administration. EM did not affect the normal blood glucose level and LD50 was about 6,250㎎/㎏. EM pretreatment in STZ-induced diabetic rats slightly inhibited Weight loss and water consumption. EM pretreatment in STZ-induced diabetic rats slightly inhibited the rise of serum glucose concentration. Serum transaminase(AST, ALT) and sorbitol dehydrogenase(SDH) were slightly increased by STZ induced changes in the serum glucose level.

골반내에 발생한 Proximal-type 유상피성 육종 1예

길준철,이상수,전병화,김성훈,손우석,목정은,박양순,강길현 대한부인종양 콜포스코피학회 2003 Journal of Gynecologic Oncology Vol.14 No.4

유상피성 육종은 매우 드문 악성 연조직 육종으로, 전형적인 경우들은 주로 젊은 남성의 수부, 전완부와 같은 신체의 원위부에 피하 혹은 심재성 피부 종괴로 발생하며, 조직학적 소견상 적은 비정형성을 나타내는 유상피성 세포와 방추형 세포의 증식에 의한 다발성 결절 형태의 배열을 보인다. 최근에 전형적인 유상피성 육종과 조직학적 유사성을 가지나 더 공격적인 형태인 proximal-type 유상피성 육종이 보고되었으며, proximal-type은 전형적인 유상피성 육종에 비하여 현저한 유상피성 세포의 발현과 매우 심한 비정형성을 나타내며, 세포가 매우 크고, 소포성 핵과 뚜렷한 핵소체를 보이며, 자주 rhabdoid 세포의 양상을 띈다. 임상적으로는 전형적인 형태에 비하여 호발 연령이 조금 늦고, 주로 체간부에, 특히 골반, 회음부, 생식기 등과 같은 심부에 발생하고, 더욱 공격적인 양상을 나타낸다. 저자들은 13세 소녀에서 원발부위를 알 수 없는, 골반내에 발생한 proximal-type 유상피성 육종 1예를 경험하여, 문헌 고찰과 함께 보고하는 바이다. Epithelioid sarcoma is a rare malignant soft-tissue sarcoma with an unknown histiogenesis, typically presenting as a subcutaneous or deep dermal mass lesion in the distal portions of the extremities of young adults. Recently, a more aggressive, so-called 'proximal-type' epithelioid sarcoma has been reported. In contrast to conventional epithelioid sarcoma, the proximal type is characterized by a predominantly large cell epithelioid cytomorphology, marked cytologic atypia, and frequent occurrence of rhabdoid features in most patients. Proximal-type epithelioid sarcoma has a predilection for appearing in the genitalia, especially the vulva, penis, pelvis and buttocks. Also this lesion appears to be somewhat more aggressive or at least metastasizes earlier than the conventional epithelioid sarcoma. We report a 13-year-old girl who presented with a buge mass filling the pelvic cavity which was painful, hard and fixed on palpation, and was radiologically diagnosed as a malignant germ cell tumors on the CT scan. The mass was surgically excised and pathologically proved to be an proximal-type epithelioid sarcoma of unknown origin.

Neural substrates of risky decision making in individuals with Internet addiction

Seok, Ji-Woo,Lee, Kyung Hwa,Sohn, Sunju,Sohn, Jin-Hun SAGE Publications 2015 Australian and New Zealand journal of psychiatry Vol.49 No.10

<P><B>Objective:</B></P><P>With the wide and rapid expansion of computers and smartphones, Internet use has become an essential part of life and an important tool that serves various purposes. Despite the advantages of Internet use, psychological and behavioral problems, including Internet addiction, have been reported. In response to growing concern, researchers have focused on the characteristics of Internet addicts. However, relatively little is known about the behavioral and neural mechanisms that underlie Internet addiction, especially with respect to risky decision making, which is an important domain frequently reported in other types of addictions.</P><P><B>Method:</B></P><P>To examine the neural characteristics of decision making in Internet addicts, Internet addicts and healthy controls were scanned while they performed a financial decision-making task.</P><P><B>Results:</B></P><P>Relative to healthy controls, Internet addicts showed (1) more frequent risky decision making; (2) greater activation in the dorsal anterior cingulate cortex and the left caudate nucleus, which are brain regions involved in conflict monitoring and reward, respectively; and (3) less activation in the ventrolateral prefrontal cortex, an area associated with cognitive control/regulation.</P><P><B>Conclusion:</B></P><P>These findings suggest that risky decision making may be an important behavioral characteristic of Internet addiction and that altered brain function in regions associated with conflict monitoring, reward and cognitive control/regulation might be critical biological risk factors for Internet addiction.</P>

제주도 남서부 송악산 응회환의 분출 및 퇴적환경

윤우석(Woo Seok Yoon),김기범(Gi Bom Kim),윤석훈(Seok Hoon Yoon),손영관(Young Kwan Sohn) 대한지질학회 2013 대한지질학회 학술대회 Vol.2013 No.10

난소종양에서 Cyclooxygenase - 2 의 발현

손우석(Woo Seok Sohn),민봉식(Bong Sik Min),김창모(Chang Mo Kim),김성주(Sung Joo Kim),강정배(Jung Bae Kang),박혜림(Hye Rim Park),장봉림(Pong Rheem Jang) 대한산부인과학회 2001 Obstetrics & Gynecology Science Vol.44 No.7

N/A Objective: A large body of evidence suggests that cyclooxygenase-2 (COX-2) is important in tumorigenesis of gastrointestinal and other cancers. This was the study to determine whether COX-2 was also expressed in benign and malignant ovarian tumors. Methods: We studied the expression of COX-2 in various ovarian tumors [ Benign epithelial tumors (n=10), borderline epithelial tumors (n=12), malignant epithelial tumor (n=12), nonepithelial tumors(n=10) ] by immunohistochemistry. Results of immunoreactivity was classified semiquantitatively based on the proportion and intensity of tumor cell immunostaining. Results: In the epithelial ovarian tumors, the intensity of immunostaining was stronger in the malignant tumors than the benign and borderline tumors (p<0.001). Especially all serous and mucinous malignant tumors (n=9) showed weak and strong immunoreactivity, with 66.7% strong reactivity. None of the nonepithelial ovarian tumors expressed COX-2 immunoreactivity. Conclusion: These preliminary data indicate that COX-2 may have a role in carcinogenesis of epithelial ovarian tums, especially in the serous and mucinous types. COX-2 maybe a target for future research in the tumorigenesis of the epithelial ovarian malignancies.

의과대학생들의 성격성향과 관련된 환자중심적 태도

문석우(Seok Woo Moon),남범우(Beom Woo Nam),서정석(Jeong Seok Seo),류은정(Eun Jeong Ryu),권혁중(Hyuk Jung Kweon),손인기(In Ki Sohn),함 웅(Woong Hahm) 한국의학교육학회 2006 Korean journal of medical education Vol.18 No.1

Purpose: The patient-centered attitude is an effort to understand patients themselves as well as their disease. The doctor-oriented approach has been shifting to one where patients and participate in the deciding of medical service. We performed this study to investigate the patient-centeredness and influencing variables associated with personality traits. Methods: We recruited 94 medical students before their psychiatric clinical clerkship, and all subjects were assessed by a structured questionnaire including socio-demographic data, Minnesota Multiphasic Personality Inventory (MMPI), Meyers-Briggs type indicator (MBTI), the patientpractitioner Orientation Scale (PPOS), and the Authoritarian Personality scale (AP), The AP and PPOS questionnaires were repeated after the psychiatric clinical clerkship. Results: After the psychiatric clinical clerkship, the AP scores were significantly lower than before, and the PPOS significantly higher than before. The change in the AP scores were related to MBTI, correlated with MMPI subscales, however, inversely correlated with the changes in PPOS after the clinical clerkship. Conclusion: The authoritarian personality trait was related to, not only the personality trait including MBTI and MMPI subscales, but also to patient-centeredness in medical students.

증례 : 방광에 발생한 Malacoplakia 1 예 ( Case Report : Malacoplakia of Bladder - A Case Report - )

손우석(Woo Seok Sohn),이충현(Choong Hyun Lee),장성구(Sung Goo Chang),채수응(Soo Eung Chai) 경희대학교 경희의료원 1988 慶熙醫學 Vol.4 No.2