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( Weizhi Zhong ),( Kunqi Chen ),( Xin Liu ),( Jianjiang Zhou ) 한국인터넷정보학회 2017 KSII Transactions on Internet and Information Syst Vol.11 No.3
In order to utilize the licensed channel of cognitive radio (CR) when the primary user (PU) is detected busy, a benefit-exchange access mode based on cooperative communication is proposed to allow secondary user (SU) to access the busy channel through giving assistance to PU`s communication in exchange for some transmission bandwidth. A holistic joint optimization problem is formulated to maximize the total throughput of CR system through jointly optimizing the parameters of cooperative spectrum sensing (CSS), including the local sensing time, the pre-configured sensing decision threshold, the forward power of cooperative communication, and the bandwidth and transmission power allocated to SUs in benefit-exchange access mode and traditional access mode, respectively. To solve this complex problem, a combination of bi-level optimization, interior-point optimization and exhaustive optimization is proposed. Simulation results show that, compared with the tradition throughput maximizing model (TTMM), the proposed holistic joint optimization model (HJOM) can make use of the channel effectively even if PU is busy, and the total throughput of CR obtains a considerable improvement by HJOM.
Juan Zhao,Wei Ma,Weizhi Chen,Jie Gao,Chunling Li,Yahong Tong,Qin Zhou,Xiuling Zhao,Menghua Wang,Huan Xiao,Yanrong Jin 한국통합생물학회 2019 Animal cells and systems Vol.23 No.6
Endometriosis (EMs) is one of the most common gynaecological diseases in women of childbearing age. Astrocyte elevated gene-1 (AEG-1) is associated with the invasion, migration, apoptosis and prognosis of various cancers. However, the roles of AEG-1 in EMs and its corresponding molecular mechanism are still unknown. In this study, animal models of EMs were established and mice were divided into two groups (n = 10): Sham group and EMs group. The EMs cells were isolated from EMs model. The AEG-1 gene was knocked down by shRNA, while the SOCS1 gene was knocked down by siRNA. Histological changes, AEG-1 expression in tissues and inflammatory factors level were detected by H&E staining, immunohistochemistry and ELISA, respectively. RTqPCR and western blotting were used to determine the expression level of related proteins. The present study found AEG-1 was up-regulated in the EMs model. Enhanced AEG-1 promoted inflammatory cell infiltration, and elevated the levels of IL-1β, IL-6, and TNF-α in EM group (p < 0.05). Besides, AEG-1 overexpression promoted the expression of NALP3, ASC and Cleavedcaspase- 1, while decreased SOCS1 level (p < 0.05). Decrease of SOCS1 further promoted the formation of NALP3 inflammasome. The inhibitory effect of AEG-1 on SOCS1 was weakened after the addition of MG-132 (p < 0.01). Furthermore, silencing AEG-1 alone increased SOCS1 level, decreased the levels of inflammatory cytokines, thereby inhibited the formation of NALP3 inflammasome. All these results demonstrated that AEG-1 aggravated inflammation via promoting NALP3 inflammasome formation in murine endometriosis lesions.
LingLi Zhang,Han Wang,Moyun Chen,Ji Ma,Weizhi Wang 한국고분자학회 2013 Macromolecular Research Vol.21 No.10
A family of polymers based on fluorene including homopolymers, alternating copolymers and two fourarmed polymers are synthesized by polycondensation. Their ability to selectively wrap specific (n, m) species using HiPco single-walled carbon nanotubes (SWNTs) as a raw material is investigated. Fluorescence, absorption and Raman spectroscopies are used to analyze SWNT species after addition to polymer suspensions. The results show separation of (n, m) SWNTs can be realized using an optimized polymer structure. The optimized polymer contains fluorene in the main chain to preferentially separate semiconducting nanotube species and hydrofluoric acid (HF)-degradable disilane groups so that it can be removed from the SWNTs after separation. We used the enriched SWNTs to prepare a solution-processed field-effect transistor with a random nanotube network in the active channel to demonstrate the selectivity of the polymer for (n, m) SWNTs. The device exhibits stable p-type semiconductor behavior in air with an on/off current ratio of 121 and hole mobility of 3.2 cm2V-1s-1.
de Lorenzo, Ví,ctor,Prather, Kristala LJ,Chen, Guo‐,Qiang,O'Day, Elizabeth,von Kameke, Conrad,Oyarzú,n, Diego A,Hosta‐,Rigau, Leticia,Alsafar, Habiba,Cao, Cong,Ji, Weizhi,Okano John Wiley and Sons Inc. 2018 EMBO reports Vol.19 No.4
<P>The UN's Sustainable Development Goals present a challenge for biotechnology to develop new environmentally‐friendly and sustainable products and production processes. </P>