Electrospun Fibrous Silk Fibroin/Poly(L-Lactic Acid) Scaffold for Cartilage Tissue Engineering

Weiwei Liu,Zhengqiang Li,Lu Zheng,Xiaoyan Zhang,Peng Liu,Ting Yang,Bing Han 한국조직공학과 재생의학회 2016 조직공학과 재생의학 Vol.13 No.5

For successful tissue engineering of articular cartilage, a scaffold with mechanical properties that match those of natural cartilage as closely as possible is needed. In the present study, we prepared a fibrous silk fibroin (SF)/poly(L-lactic acid) (PLLA) scaffold via electrospinning and investigated the morphological, mechanical, and degradation properties of the scaffolds fabricated using different electrospinning conditions, including collection distance, working voltage, and the SF:PLLA mass ratio. In addition, in vitro cell-scaffold interactions were evaluated in terms of chondrocyte adhesion to the scaffolds as well as the cytotoxicity and cytocompatibility of the scaffolds. The optimum electrospinning conditions for generating a fibrous SF/PLLA scaffold with the best surface morphology (ordered alignment and suitable diameter) and tensile strength (~1.5 MPa) were a collection distance of 20 cm, a working voltage of 15 kV, and a SF:PLLA mass ratio of S50P50. The degradation rate of the SF/PLLA scaffolds was found to be determined by the SF:PLLA mass ratio, and it could be increased by reducing the PLLA proportion. Furthermore, chondrocytes spread well on the fibrous SF/PLLA scaffolds and secreted extracellular matrix, indicating good adhesion to the scaffold. The cytotoxicity of SF/PLLA scaffold extract to chondrocytes over 24 and 48 h in culture was low, indicating that the SF/PLLA scaffolds are biocompatible. Chondrocytes grew well on the SF/PLLA scaffold after 1, 3, 5, and 7 days of direct contact, indicating the good cytocompatibility of the scaffold. These results demonstrate that the fibrous SF/PLLA scaffold represents a promising composite material for use in cartilage tissue engineering.

Research on Communication and Education of Doctor-Patient Relationship

Liu Weiwei(刘,薇薇),Gao Xi(高西) 아시아사회과학학회 2022 International Science Research Vol.2 No.1

确定违反保密规定的习惯和影响,以及医患关系中沟通失误的原因和影响。本文是基于健康传播伦理问题的综合文献综述是在数据库(PubMed 和 Google Scholar)中进行的。关键词为“医疗机密”和“机密泄露”,用于“机密泄露”搜索,以及“沟通失误”搜索中的“医患关系沟通失误”。审查了他们的参考清单,获得并分析了相关的参考清单。违反保密规定的情况屡见不鲜,而且大多数都是偶然发生的。这主要是由医生实施的,严重的保密违规更经常发生,最常见的披露信息是患者的临床和/或个人数据。在对话和数据输入过程中可能会违反保密性。这主要导致医生的职业后果和处罚,以及患者的健康状况较差。沟通失误也可能导致健康状况不佳。有许多因素导致了错误沟通的发生。它可能发生在医务人员、医务人员和患者之间,以及医务人员和患者亲属之间。在大多数国家,违反保密规定和错误沟通是两个主要问题,导致医患关系恶化,造成诸多不利因素,尤其是患者健康状况不佳。虽然有各种原因,但它们的发生往往是由于医生意识的缺乏。应提高保密意识和沟通重要性。 To identify the customary and impacts of confidential breach as well as miscommunication causes and impacts in doctor-patient relationship. This comprehensive literature review on ethical issues of health communication was performed in databases (PubMed and Google Scholar). All English-language relevant articles with keywords “medical confidentiality” and “confidentiality breach” for “confidentiality breach” search and “miscommunication in doctor patient relationship” in “miscommunication” search were analyzed. Their reference lists were reviewed and the relevant ones were obtained and analyzed. Confidentiality breaches happen commonly and most of them are accidental. It is mostly committed by doctors and severe confidentiality breaches occur more often with the most common disclosed information is patients’ clinical and/or personal data. Breaching confidentiality can happen during conversation and data entry. It results mainly in professional consequences and sanctions for the doctors, as well as poorer health outcomes of the patients. Poor health outcomes can also be resulted from miscommunication. There are numerous factors grounding the occurrences of miscommunication. It can happen between medical professionals, medical professionals and patients, and medical professionals and patients’ relatives. Confidentiality breach and miscommunication are two major issues in most countries which result in poor doctor-patient relationship that cause numerous disadvantages, particularly poor patients’ health outcome. Although there are various reasons, they usually happen due to awareness lack of the doctors. Awareness of confidentiality and communication importance should be improved.

Hardness Prediction and First Principle Study of Re-123(Re = Y, Eu, Pr, Gd) Superconductors

Liu, Weiwei,Zhou, Y.P.,Feng, X.L. Korean Chemical Society 2009 Bulletin of the Korean Chemical Society Vol.30 No.12

The chemical bond parameters of Y-123, Eu-123, Pr-123 and Gd-123 compounds have calculated using the chemical bond theory of complex crystals. Their hardness have been predicted by the chemical bond definition of hardness. The calculated results indicate that the Ba-O and RE-O types of bond have a lower covalent character and the Cu-O types of bond have greater covalency. The hardness values increase as the unit cell volume of the rare earth superconductor structures decrease.

Molecular Weight Distribution of Liquid Phase AN and Solid Phase Polymer in Precipitation Polymerization of AN By Changing Solution Composition and Temperature

Weiwei Liu,Shuangkun Zhang,Jing Wang,Seung Kon Ryu,Ri-Guang Jin 한국탄소학회 2012 Carbon Letters Vol.13 No.3

According to kinetic mechanisms, liquid phase polymerization and solid phase polymerization are different in acrylonitrile (AN) polymerization, and so the relationship between the contribution ratio and molecular weight distribution (MWD) was obtained through theoretic analysis. The precipitation homopolymerization of AN was carried out in a mixture solution of dimethyl sulfoxide (DMSO) and water at 50~65℃ using α,α'-azobisisobutyronitrile as an initiator. The contribution ratio decreased and approached 0; the MWD also decreased and approached 2 with the increase of the H2O/DMSO ratio from 10/90 to 90/10. The experimental data were found to coincide well with the theoretical equation derived from the mechanisms.

A Simulation Study of Urban Public Transport Transfer Station Based on Anylogic

( Weiwei Liu ),( Fu Wang ),( Chennan Zhang ),( Jingyu Zhang ),( Lei Wang ) 한국인터넷정보학회 2021 KSII Transactions on Internet and Information Syst Vol.15 No.4

With the increase in the population of our cities and the rapid increase in the number of private cars, urban traffic has become more and more congested. At this stage, urban public transportation has become one of the main ways to improve urban traffic congestion. Aiming at the problem of how to improve the basic capacity of buses in multi-line transfer stations, this paper conducts simulation research based on anylogic software. Through micro-simulation analysis of vehicles entering, stopping, and exiting the station, combined with the delay model theory, the vehicle is given Stop organization optimization and station layout improvement methods, so that vehicles can run in the station more stably, smoothly and safely. Case analysis shows that applying this method to the roadside parking problem, the main and auxiliary bus stations have a significant improvement in operating capacity compared with the conventional tandem double bus stations, and the service level of the main and auxiliary bus stations has been significantly improved.

Designing Rich-Secure Network Covert Timing Channels Based on Nested Lattices

( Weiwei Liu ),( Guangjie Liu ),( Xiaopeng Ji ),( Jiangtao Zhai ),( Yuewei Dai ) 한국인터넷정보학회 2019 KSII Transactions on Internet and Information Syst Vol.13 No.4

As the youngest branch of information hiding, network covert timing channels conceal the existence of secret messages by manipulating the timing information of the overt traffic. The popular model-based framework for constructing covert timing channels always utilizes cumulative distribution function (CDF) of the inter-packet delays (IPDs) to modulate secret messages, whereas discards high-order statistics of the IPDs completely. The consequence is the vulnerability to high-order statistical tests, e.g., entropy test. In this study, a rich security model of covert timing channels is established based on IPD chains, which can be used to measure the distortion of multi-order timing statistics of a covert timing channel. To achieve rich security, we propose two types of covert timing channels based on nested lattices. The CDF of the IPDs is used to construct dot-lattice and interval-lattice for quantization, which can ensure the cell density of the lattice consistent with the joint distribution of the IPDs. Furthermore, compensative quantization and guard band strategy are employed to eliminate the regularity and enhance the robustness, respectively. Experimental results on real traffic show that the proposed schemes are rich-secure, and robust to channel interference, whereas some state-of-the-art covert timing channels cannot evade detection under the rich security model.

Study on the scattering of 2-D Rayleigh waves by a cavity based on BEM simulation

Weiwei Liu,조윤호,PHANHAI DANG,Jan D. Achenbach 대한기계학회 2011 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.25 No.3

A frequency domain boundary element method is introduced in this paper to simulate the scattering of two-dimensional Rayleigh waves by a cavity on the surface of an elastic half-space. This numerical method allows the Rayleigh wave to escape the truncated boundary without producing any spurious reflections. The numerical results of the displacements and stresses of a 2-D Rayleigh wave which travels along a flat surface of an elastic half-infinite medium are in good agreement when compared with theoretical ones. The problem of a Rayleigh wave scattering by a cavity on the surface of an elastic half-infinite medium is simulated by the proposed numerical method. The result is taken as the benchmark to introduce an approximate analytical method for such problems of scattering by a cavity on the surface. This numerical method is formulated for a two-dimensional homogeneous, isotropic, linearly elastic half-space and its implementation in a frequency domain boundary scheme is discussed in detail.

Hardness Prediction and First Principle Study of Re-123(Re = Y, Eu, Pr, Gd) Superconductors

Weiwei Liu,Y. P. Zhou,X. L. Feng 대한화학회 2009 Bulletin of the Korean Chemical Society Vol.30 No.12

The chemical bond parameters of Y-123, Eu-123, Pr-123 and Gd-123 compounds have calculated using the chemical bond theory of complex crystals. Their hardness have been predicted by the chemical bond definition of hardness. The calculated results indicate that the Ba-O and RE-O types of bond have a lower covalent character and the Cu-O types of bond have greater covalency. The hardness values increase as the unit cell volume of the rare earth superconductor structures decrease.

疫情防控常态化下医学院校康养专业人才培养的问题与策略研究

刘薇(Weiwei Liu),何姗(Shan He) 아시아사회과학학회 2022 International Science Research Vol.2 No.3

In order to further improve the public health emergency prevention and control mechanism and strengthen the construction of public health talent team, medical universities in China will gradually establish and improve the cultivation system of health care professionals, and provide health care professionals with more high-quality medical universities talent resources. Under the current situation, although most medical universities in China are actively preparing for the cultivation of high-quality talents for health care professionals, on the whole, there are still many problems in the cultivation mode of health care professionals in medical universities in China that need to be solved urgently. This paper elaborates on the training mode and system of health care professionals in the context of the normalization of epidemic prevention and control, aiming to clarify the system construction of health care professionals in medical universities, improve the specifications and levels of health care professionals, and further promote the healthy and orderly development of China's health care industry.

The Media Literacy of Residents in Southwestern China During the COVID-19 Epidemic

Shan He(Shan He),Lili Yao(Lili Yao),Xingyu Zhao(Xingyu Zhao),Weiwei Liu(Weiwei Liu) 아시아사회과학학회 2023 International Science Research Vol.3 No.2

Objective To measure residents’ abilities to acquire, analyze and evaluate information on media in southwestern China and to explore its predictive factors. Methods The convenience sampling method was used. A web-based questionnaire survey was conducted among 774 residents during the Spring Festival in 2020. Results Young, highly educated, unmarried, high-income, and urban residents preferred to seek and acquire information about COVID-19 epidemic through new media channels. Elderly residents tended to obtain information through television. Residents with low educational background and rural residents were more dependent on community information media. To analyze residents’ abilities in the judgement of 15 statements about COVID-19, residents with a master’s degree or above (OR = 2.755, [95% CI 1.160-6.542]) had better media literacy in identifying false health information released on social networking. Rural residents (OR = 0.609, [95% CI 0.433-0.855]) had lower media literacy. The total score decreased by 2.6% for every one-year increase of age. Conclusion Residents’ abilities to acquire, analyze and evaluate information were affected by their demographic characteristics in southwestern China. The authorities and local communities should develop different approaches of information dissemination, with the help of traditional and new media. It is important to improve the level of residents' media literacy, in order to achieve better effect in information dissemination and reception.