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SOME RELATIONS ON PARAMETRIC LINEAR EULER SUMS
Weiguo Lu,Ce Xu,Jianing Zhou Korean Mathematical Society 2023 대한수학회보 Vol.60 No.4
Recently, Alzer and Choi [2] introduced and studied a set of the four linear Euler sums with parameters. These sums are parametric extensions of Flajolet and Salvy's four kinds of linear Euler sums [9]. In this paper, by using the method of residue computations, we will establish two explicit combined formulas involving two parametric linear Euler sums S<sup>++</sup><sub>p,q</sub> (a, b) and S<sup>+-</sup><sub>p,q</sub> (a, b) defined by Alzer and Choi, which can be expressed in terms of a linear combinations of products of trigonometric functions, digamma functions and Hurwitz zeta functions.
A Network Partition Approach for MFD-Based Urban Transportation Network Model
( Haitao Xu ),( Weiguo Zhang ),( Zuozhang Zhuo ) 한국인터넷정보학회 2020 KSII Transactions on Internet and Information Syst Vol.14 No.11
Recent findings identified the scatter and shape of MFD (macroscopic fundamental diagram) is heavily influenced by the spatial distribution of link density in a road network. This implies that the concept of MFD can be utilized to divide a heterogeneous road network with different degrees of congestion into multiple homogeneous subnetworks. Considering the actual traffic data is usually incomplete and inaccurate while most traffic partition algorithms rely on the completeness of the data, we proposed a three-step partitioned algorithm called Iso-MB (Isoperimetric algorithm - Merging - Boundary adjustment) permitting of incompletely input data in this paper. The proposed algorithm was implemented and verified in a simulated urban transportation network. The existence of well-defined MFD in each subnetwork was revealed and discussed and the selection of stop parameter in the isoperimetric algorithm was explained and dissected. The effectiveness of the approach to the missing input data was also demonstrated and elaborated.
The Effect of Na0.44MnO2 Formation in Na+-Modified Spinel LiMn2O4
Lilong Xiong,Youlong Xu,Weiguo Wu,Pei Lei,Tao Tao,Xin Dong 대한금속·재료학회 2014 ELECTRONIC MATERIALS LETTERS Vol.10 No.4
Na0.44MnO2 impure phase is formed during the synthetic process of Na+-modified spinel LiMn2O4 by solid state reaction which is confirmed by x-ray diffraction analysis. Scanning electron microscopy, transmission electron microscopy and galvanostatic charge-discharge measurements are carried out to investigate the effect of the formation of Na0.44MnO2 impurity on the morphology and electrochemical properties of the spinel material. The results show that the spinel material with impure phase exhibits improved cyclability compared to that of the pristine LiMn2O4. The improved electrochemical performance is mainly ascribed to the improved crystallinity of the spinel particles, enhanced stability of the spinel structure and good electronic conductivity of the composite.
Synthesis of Cobalt-Iron Prussian Blue Analogues Nanotubes by CTAB Soft-Template Method
Liu, Peng,Liang, Chuanghui,Xu, Jianfeng,Fang, Jian,Zhao, Jihua,Shen, Weiguo Korean Chemical Society 2010 Bulletin of the Korean Chemical Society Vol.31 No.5
Three cobalt-iron Prussian Blue Analogues (PBAs) nanotubes contained with different alkali metal cations of K, Rb or Cs, respectively, were prepared by using cetyltrimethylammonium bromide (CTAB)/ethanol-water micelles as soft templates. The products were characterized by energy-dispersive X-ray spectroscopy (EDS), X-ray diffraction (XRD), transmission electron microscopy (TEM) and scanning electron micrograph (SEM), which confirmed the composition of the substances and their unique nanotube structures. Furthermore, the formation mechanism of the PBAs nanotubes was discussed and provided useful insight for further synthesis of nanotubes of other Prussian blue analogues.
The management of hydatidiform mole with lung nodule: a retrospective analysis in 53 patients
Xiao Li,Yaping Xu,Yuanyuan Liu,Xiaodong Cheng,Xinyu Wang,Weiguo Lu,Xing Xie 대한부인종양학회 2019 Journal of Gynecologic Oncology Vol.30 No.2
Objective: To investigate the significance of lung nodule in hydatidiform mole, we retrospectively compared the clinical outcomes of those patients treated with different strategies. Methods: The patients were divided into three groups: chemotherapy immediately once lung nodule was detected (group 1, n=17), delayed chemotherapy until human chorionic gonadotrophin (hCG) level met the diagnostic criteria for gestational trophoblastic neoplasia (GTN) (group 2, n=18), and hCG surveillance alone until hCG level was normalized spontaneously (group 3, n=18). The clinical parameters of these patients were collected and analyzed. Results: Totally 53 (4.0%) patients were included from 1,323 cases with molar pregnancy during past 16 years. Among them, the diameters of lung nodules were 0.3–2.5 cm. Chemotherapy cycles for achieving hCG normalization and the failure rate of first-line chemotherapy in group 1 were significantly increased than that in group 2 (5 vs. 3 cycles, p=0.000, 58.8% vs. 11.1%, p=0.005). The hCG level of all 18 cases in group 3 was normalized spontaneously within 6 months. Of those, lung nodules of 9 patients disappeared spontaneously, accounting for 25% (9/36) of patients who initially selected observation. The proportion of single nodule in group 3 was significantly higher than that in group 2 (10/18 vs. 2/18, p=0.012). Conclusion: Our results suggest that lung nodule alone is not an adequate indication of chemotherapy in molar pregnancy. hCG surveillance is safe for patients with lung nodule, especially with single nodule, as long as their hCG levels do not meet International Federation of Gynecology and Obstetrics diagnostic criteria for GTN.
XIUHUA ZHAO,JIAMING TANG,YUANGANG ZU,WEIGUO WANG,NA LI,WENJIA XU 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2013 NANO Vol.8 No.6
This work investigated the preparation process of folate-conjugated bovine serum albumin nanoparticles (FA–BSANPs) adsorbing epirubicin hydrochloride (EPI) nanoparticles (FA–EPI–BSANPs), a specific-targeting drug delivery system in cancer chemotherapy. The BSANPs were prepared by desolvation as a drug carrier system and conjugated with folate to produce FA–EPI–BSANPs that specifically target tumors by cross-linking. EPI, an anticancer drug, was adsorbed by this drug carrier system. The influences of six experimental parameters, namely, the adsorption time, FA–BSANPs solution-adsorbed EPI concentration, stirring speed, FA–BSANPs solution pH, the ratio of glutaraldehyde and BSA, and mass ratio of FA–BSANPs to EPI, on the drug loading efficiency (DLR) and drug entrapment efficiency (DER) of FA–EPI–BSANPs were investigated via the single factor method. The results indicated that the optimum operation conditions were obtained with 145.4 nm±0.5 nm MPS, 23.41% DLR and 98.93% DER. The N-hydroxysuccinimide-folate content associated with BSANPs was up to 0.9757% (wt). The DLR and DER of EPI increased with increasing adsorption time, FA–BSANPs solution concentration, and pH value, peaking at 1750 rpm with increasing stirring speed, but decreasing thereafter. The FA–EPI–BSANPs obtained were characterized by laser light scattering, scanning electron microscopy, Fourier transform infrared spectroscopy, differential scanning calorimetry, X-ray diffraction and thermogravimetric analysis. Drug release in vitro was investigated, as well. The characterization results showed that EPI in FA–EPI–BSANPs existed in an amorphous, instead of crystalline state. Most of the EPI was enclosed by FA–BSANPs, and a small amount was adsorbed onto the surface of the FA–BSANPs. The FA–EPI–BSANPs particles are nearly ellipsoidal and significantly affect sustained release. The inhibitory rate of FA–EPI–BSANP was mensurated by MTT method. The inhibitory rate of FA–EPI–BSANPs for SMMC 7721 cell developed with raise of concentration and was higher than other samples. The IC50 values of FA–EPI–BSANPs and EPI were 11.5 μg/mL and 18.8 μg/mL, respectively. The target ability of FA–EPI–BSANP for SMMC 7721 cell was mensurated by fluorescence (FITC) modified albumin techniques. The uptake rate of FA–EPI–BSANPs was higher than samples without folate conjugated, and increased with increased concentration.
SURF4 maintains stem-like properties via BIRC3 in ovarian cancer cells
Yongfang Yue,Lili Xia,Shanshan Xu,Conghui Wang,Xinyu Wang,Weiguo Lu,Xing Xie 대한부인종양학회 2020 Journal of Gynecologic Oncology Vol.31 No.4
Objective: As cancer stem cells (CSCs) are considered as the origin of tumor development,recurrence, and drug resistance, we aimed to explore the mechanism related to modulatingstemness in CSCs, thus facilitating to search for new therapeutic strategy for ovarian cancer. Methods: In this study, ovarian cancer stem cells (OCSCs) induced from cell line 3AOand A2780 were enriched in serum-free medium (SFM). The effect of SURF4 on CSC-likeproperties was evaluated by sphere-forming assays, re-differentiation assays, quantitativereal-time polymerase chain reaction, flow cytometry, Western blotting, cell viability assaysand in vivo xenograft experiments. The downstream molecule participating in SURF4maintaining stemness was screened by RNA-sequencing and identified by the experiments ofgene function. Results: SURF4 was upregulated expressed in OCSCs. Knockdown of SURF4 reduced theexpression of the related stem markers (SOX2 and c-MYC), inhibited self-renewal ability,and improved the sensitivity to chemotherapeutic drugs (paclitaxel and cisplatin) in OCSCs. SURF4 knockdown also inhibited tumorigenesis in nonobese diabetic/severe combinedimmunodeficiency mice. BIRC3 expression was controlled by SURF4, and BIRC3 showedthe similar effect as SURF4 did, and BIRC3 overexpression partially recovered stem-likeproperties abolished by SURF4 knockdown. Conclusion: Our findings suggest that SURF4 possesses the ability to maintain stemness ofOCSCs via BIRC3, and may serve as a potential target in stem cell-targeted therapy forovarian cancer.