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- 저자 : Weidong Ren (검색결과 9 건)
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Ren San,Weidong Yue,Surong Hasi 대한수의학회 2019 Journal of Veterinary Science Vol.20 No.2
The effects of CYP1A enzyme on the pharmacokinetics of p-acetaminophen were studied in Bactrian camel. Twelve Bactrian camels were divided into 2 groups, then given a single dose of p-acetaminophen only or with the enzyme inhibitor lomefloxacin. Blood samples were collected after different intervals, and p-acetaminophen concentration was determined by high-performance liquid chromatography. Pharmacokinetic parameters were analyzed by Phoenix WinNonLin v.7.0. The results show that lomefloxacin can significantly inhibit Bactrian camel CYP1A enzyme, as evidenced by the prolonged elimination halflife, increased maximum plasma concentration and area under the curve values and the shortened time to peak concentration for p-acetaminophenol in the substrate with inhibitor group. The results lay a foundation for revealing the particular characteristics of the CYP1A enzyme in Bactrian camels.
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Filtration and regeneration behavior of polytetrafluoroethylene membrane for dusty gas treatment
Weidong Zhang,Deqiang Jiang,Junteng Liu,Zhongqi Ren,Wang Geng 한국화학공학회 2008 Korean Journal of Chemical Engineering Vol.25 No.4
With micron talcum particles and nano-CaCO3 powder as test dust, a series of experiments have been carried out to systematically study the gas filtration and regeneration behavior of polytetrafluoroethylene membrane, and some comparisons were made with common filter media. The experimental results showed that the PTFE membrane had a filtration efficiency of above 99.99% for micron particles, and excellent regeneration behavior was obtained, though a much higher initial pressure drop existed. Based on the results, it was concluded that the PTFE membrane is an excellent surface-filtration media for micron particles. Effects of operation parameters, including airflow velocity, particle concentration and particle characteristics were also investigated. To better understand the evolution of pressure drop during the filtration process, a mathematical model with operation parameters and characteristics of particles was derived from the gas-solid two-phase flow theories. A novel method on the determination of regeneration period of the filter media was put forward based on the analysis of the pressure drop according to this model
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Ren San,Weidong Yue,Surong Hasi 대한수의학회 2019 Journal of Veterinary Science Vol.20 No.3
The effects of CYP1A enzyme on the pharmacokinetics of p-acetaminophen were studied in Bactrian camel. Twelve Bactrian camels were divided into 2 groups, then given a single dose of p-acetaminophen only or with the enzyme inhibitor lomefloxacin. Blood sampleswere collected after different intervals, and p-acetaminophen concentration was determined by high-performance liquid chromatography. Pharmacokinetic parameters were analyzedby Phoenix WinNonLin v.7.0. The results show that lomefloxacin can significantly inhibit Bactrian camel CYP1A enzyme, as evidenced by the prolonged elimination half-life, increased maximum plasma conce[INSERT FIGURE 001]ntration and area under the curve valuesand the shortened time to peak concentration for p-acetaminophenol in the substrate with inhibitor group. The results lay a foundation for revealing the particular characteristics of the CYP1A enzyme in Bactrian camels.
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Miao Shui,Weidong Zheng,Jie Shu,Qingchun Wang,Shan Gao,Dan Xu,Liangliang Cheng,Lin Feng,Yuanlong Ren 한국물리학회 2013 Current Applied Physics Vol.13 No.3
Lithium-ion battery cathode material Li1þxV3O8 is synthesized by a citric acid/tartaric acid assisted sol egel method and sintered at 350 C, 450 C and 550 C for 3 h for the formation of Li1þxV3O8 phase. The synthesized samples were fully characterized by FTIR, TG/DTA, XRD, SEM, EIS and chargeedischarge tests. Li1þxV3O8 material synthesized by tartaric acid assisted route and sintered at 450 C for 3 h shows best electro-chemical performance. It shows a high initial capacity of 249 mAh g1 and still reserves a discharge capacity of 260 mAh g1 after 50 cycles. Moreover, in the case of tartaric assisted products, no capacity decadence is observed in 50 cycles. XRD together with TG/DTA measurements reveal that compared with citric acid assisted products, the adoption of tartaric acid as chelating agent effectively lowers the crystallization temperature of amorphous Li1þxV3O8. Therefore, precursors obtained by tartaric acid route calcinated at 450 C for 3 h exhibit lower crystallinity and smaller grain size, which contributes to the better electrochemical performance of the cathode electrodes. From EIS measurements, the bulk resistance is reduced, which favors the intercalation and de-intercalation of lithium ions while cycling.
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Time-domain simulations of transient response in LiFePO4 cathode lithium ion batteries
Xiaoping Xu,Miao Shui,Weidong Zheng,Jie Shu,Lei Hui,Linxia Xu,Liangliang Cheng,Lin Feng,Yuanlong Ren 한국물리학회 2014 Current Applied Physics Vol.14 No.5
The time domain transients of batteries comprised of LiFePO4 cathode material exhibit large nonlinearity with the increasing discharging rates. Hence, the calculated overpotential transients match the experimental determined well only when the discharging current is low enough. The results of electrochemical impedance spectra at different OCV level indicate that the change of the parameters of equivalent circuit or even the circuit architecture are probably responsible for the large discrepancy between the predicted and the measured transient profiles. By taking the change of equivalent circuit model at high discharging current into consideration, we successfully simulate the time domain transients of polarization within the entire discharging current range. Also with the help of circuit analysis, the contribution of the ohmic resistance, charge transfer impedance and solid-state diffusion impedance to total polarization has been differentiated as a function of discharging time.
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Extraction separation of toluene/cyclohexane with hollow fiber supported ionic liquid membrane
Fan Zhang,Zhongqi Ren,Wei Sun,Junteng Liu,Weidong Zhang 한국화학공학회 2014 Korean Journal of Chemical Engineering Vol.31 No.6
A supported liquid membrane with ionic liquid was used for the separation of toluene/cyclohexane. Theinteractions of ionic liquid with toluene and cyclohexane were calculated and experimentally studied by quantum chemicalcalculation and liquid-liquid extraction process. The results showed [BPy][BF4] have stronger interaction with toluenethan that with cyclohexane. The selectivity of SILM processes was larger than 10 at the temperature of 323 K and theflow rate of 13.5 mL·min-1 on both shell side and lumen side. Due to the higher viscosity of IL, SILM process hadgood long-term stability. As the effects of mass transfer driving force of SILM process, the flux and removal efficiencyincreased with increase of initial toluene concentration, while the selectivity decreased because of the competitive transport. Base on the resistance in-series model and experimental results, the mass transfer resistance was mainly lay liquidmembrane phase. The influence of flow rates on both sides was slight. The higher temperature could enhance the masstransfer performance significantly. The removal efficiency increased from 28.2% to 45.1% with the increasing of operationtemperature from 298 K to 323 K.
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Chao Chen,Shu Chen,Miao Shui,Xiaoping Xu,Weidong Zheng,Lin Feng,Jie Shu,Yuanlong Ren 한국물리학회 2015 Current Applied Physics Vol.15 No.2
Cathode material 0.5Li2MnO3·0.5LiNi0.5Mn0.5O2 is successfully synthesized by citrate acid assisted sol -gel method and shows pretty good electro-chemical performance. To elucidate the electro-chemical reactions and charge carrier transportation kinetics in the charge-discharge process, series of electrochemical impedance spectra for the first and the second charge process are measured on multiple given state of charges. The rapid augmentation of resistance to electronic conduction and ionic conduction within the voltage range 4.45-4.6 V where the removal of Li2O from Li2MnO3 component takes place gives us more evidence about the complicated “structurally integrated” feature of this material. The relatively large span of the arc responsible for electronic conduction and the extremely large Mn3+ related charge transfer resistance at the beginning of the second charging indicate that after one complete charge-discharge cycle, Li2MnO3 and LiNi0.5Mn0.5O2 domains still reserve its original structure and will keep its structure for the followed cycles.
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Differentiation of cystic biliary atresia and choledochal cysts using prenatal ultrasonography
Lizhu Chen,Fujiao He,Kaihui Zeng,Bing Wang,Jingyu Li,Dan Zhao,Zeyu Yang,Weidong Ren 대한초음파의학회 2022 ULTRASONOGRAPHY Vol.41 No.1
Purpose: This study explored the performance of prenatal ultrasonography in the differential diagnosis of cystic biliary atresia (CBA) and choledochal cyst (CC). Methods: Fetuses diagnosed with hepatic hilar cyst in the second trimester were included in this study. A series of prenatal ultrasound examinations were performed in the second and third trimesters. The diameter of the gallbladder (GB) and hepatic cyst were measured, as well as the wall thickness of the GB. The GB-cyst connection, visibility of the right hepatic artery (RHA), and other concomitant abnormalities were carefully evaluated. A neonatal transabdominal ultrasound examination was performed within 1 week after birth, and clinical data were followed up to 6 months after birth. Results: Between January 1, 2016 and January 31, 2020, 53 fetuses diagnosed with hepatic hilar cyst were recruited. Eight were excluded because they were lost to follow-up. Among the 45 cases included in this study, 10 were diagnosed with CBA and 35 with CC after birth. Statistically significant differences were found in GB width, wall thickness, change in GB width, change in cyst length, GB-cyst connection, and RHA visibility between the CBA and CC groups. GB width showed the best diagnostic performance with an area under the curve (AUC) of 0.899. The combination of GB width, GB wall thickness, and GB-cyst connection yielded a comparable AUC of 0.971. Conclusion: The GB should be carefully evaluated in fetuses with hepatic hilar cyst. Prenatal ultrasound findings could provide suggestive parameters for the differential diagnosis of CBA from CC. Purpose: This study explored the performance of prenatal ultrasonography in the differential diagnosis of cystic biliary atresia (CBA) and choledochal cyst (CC).Methods: Fetuses diagnosed with hepatic hilar cyst in the second trimester were included in this study. A series of prenatal ultrasound examinations were performed in the second and third trimesters. The diameter of the gallbladder (GB) and hepatic cyst were measured, as well as the wall thickness of the GB. The GB-cyst connection, visibility of the right hepatic artery (RHA), and other concomitant abnormalities were carefully evaluated. A neonatal transabdominal ultrasound examination was performed within 1 week after birth, and clinical data were followed up to 6 months after birth.Results: Between January 1, 2016 and January 31, 2020, 53 fetuses diagnosed with hepatic hilar cyst were recruited. Eight were excluded because they were lost to follow-up. Among the 45 cases included in this study, 10 were diagnosed with CBA and 35 with CC after birth. Statistically significant differences were found in GB width, wall thickness, change in GB width, change in cyst length, GB-cyst connection, and RHA visibility between the CBA and CC groups. GB width showed the best diagnostic performance with an area under the curve (AUC) of 0.899. The combination of GB width, GB wall thickness, and GB-cyst connection yielded a comparable AUC of 0.971.Conclusion: The GB should be carefully evaluated in fetuses with hepatic hilar cyst. Prenatal ultrasound findings could provide suggestive parameters for the differential diagnosis of CBA from CC.
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