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Mucinous Rectal Cancer: Effectiveness of Preoperative Chemoradiotherapy and Prognosis
Shin, Ui Sup,Yu, Chang Sik,Kim, Jong Hoon,Kim, Tae Won,Lim, Seok-Byoung,Yoon, Sang Nam,Yoon, Yong Sik,Kim, Chan Wook,Kim, Jin Cheon Springer - Society of Surgical Oncology 2011 Annals of surgical oncology Vol.18 No.8
Comparison of Distance Measurement in Time Series Clustering for Predicting Bitcoin Prices
Ui-Jun Back,Mu-Gon Shin,Min-Seong Lee,Boseon Kim,Jee-Tae Park,Myung-Sup Kim 한국통신학회 2020 한국통신학회 APNOMS Vol.2020 No.09
Since the development of Bitcoin, the first blockchain-based cryptocurrency, many cryptocurrencies have formed and have traded in markets. The integrity and anonymity of cryptocurrency was enough to raise its value and its price gained worldwide attention. Therefore, many studies are being carried out to predict the price of cryptocurrency for make a profit. We cluster time series through K-Medoids algorithm and train and evaluate each cluster with predictive models. We also examine the predictive performance in Bitcoin price according to the various distance measurement of clustering.
Inquire into the Development of Politics and Economy in the Middle East
( Fan Di ),( Ui Sup Shin ) 한국외국어대학교 중동연구소 2008 중동연구 Vol.27 No.2
Under the current globalizing process, the Middle East political system reform is an inevitable historical trend, but it will not be smooth. The economic reformative approaches are necessary and important as well as the political reform. The economic reformation and cooperation in this region will make a breakthrough first in the Gulf region with the efforts of GCC. The Arab free trade region will achieve new successes, and continue to play an active role in this area. The economic and political reformative system in the Middle East are expected to achieve greater development in the middle of globalizing 21st century and to enhance their status and role in the world.
Anti-inflammatory effects of TP1 in LPS-induced Raw264.7 macrophages
Kim Minji,An Jangeun,Shin Seong-Ah,Moon Sun Young,Kim Moonsu,Choi Seyeon,Kim Huiji,Phi Kim-Hoa,Lee Jun Hyuck,Youn Ui Joung,Park Hyun Ho,Lee Chang Sup 한국응용생명화학회 2024 Applied Biological Chemistry (Appl Biol Chem) Vol.67 No.-
Inflammation is an essential defense mechanism in health; however, excessive inflammation contributes to the patho physiology of several chronic diseases. Although anti‑inflammatory drugs are essential for controlling inflammation, they have several side effects. Recent findings suggest that naturally derived compounds possess physiological activi ties, including anti‑inflammatory, antifungal, antiviral, anticancer, and immunomodulatory activities. Therefore, this study aimed to investigate the anti‑inflammatory effects and molecular mechanisms of 2,5,6‑trimethoxy‑p‑terphenyl (TP1), extracted from the Antarctic lichen Stereocaulon alpinum, using in vitro models. TP1 treatment decreased the production of nitric oxide (NO) and reactive oxygen species (ROS) in LPS‑stimulated Raw264.7 macrophages. Additionally, TP1 treatment significantly decreased the mRNA levels of pro‑inflammatory cytokines (IL‑1β, TNF‑α, IL‑6) and the mRNA and protein levels of the pro‑inflammatory enzymes (inducible nitric oxide synthase and cyclooxyge nase‑2). Moreover, TP1 suppressed lipopolysaccharide‑induced phosphorylation of the NF‑κB and MAPK signaling pathways in Raw264.7 macrophages. Conclusively, these results suggest that TP1 ameliorates inflammation by sup pressing the expression of pro‑inflammatory cytokines, making it a potential anti‑inflammatory drug for the treatment of severe inflammatory diseases.