Technical Trends of Vibration Problems for Turbine Rotors

A. Uenishi,F. Fujisawa,O. Matsushita,K. Namura,K. Hisano 대한기계학회 1987 Asia-Pacific Vibration Conference Vol.1 No.1

A Longitudinal Study of Progress in Vocabulary Size of Japanese EFL Senior High School Learners: A Comparison of the General and Commercial Courses

( Masaki Akase ),( Koji Uenishi ) 범태평양응용언어학회 2015 범태평양응용언어학회지 Vol.19 No.1

The purposes of this study are (I) to longitudinally measure the receptive vocabulary size (VS) of Japanese EFL senior high school learners; (2) to investigate how the learners develop their VS; and (3) to describe the longitudinal developmental patterns of VS of each learner during their three years of high school. Kasahara``s (2005) VS tests, a modified version of Mochizuki``s (1998) test were administered to 196 learners three times while they were in high school. Descriptive statistics were calculated and longitudinal comparisons were made, using the data of the identical subjects. One-way ANOV As and post hoc Bonferroni tests confirmed that the general course learners made progress throughout their time at school. As for the commercial course learners, they made progress during their first and second years. However, there was no statistically significant difference in average scores between the second and third years. The statistics and the line graphs of longitudinally-measured VS revealed that in the commercial course, 14.7% and 42.7% of the learners made little and or negative progress between their first and second testing and their second and third testing respectively. The study results suggest the three main factors explaining this stagnation of the commercial course learners: school curriculum; motivation; and future career path. Further research should be conducted with learners whose academic levels vary widely to investigate this learning plateau.

Response to the Editor

Hiroaki Ohta,Kazuhiro Uenishi,Masataka Shiraki 대한골다공증학회 2017 Osteoporosis and Sarcopenia Vol.3 No.1

Thank you for your letter to our publication in Osteoporosis and Sarcopenia entitled on “Recent nutritional trend of calcium and vitamin D in East Asia”. Although the increase in calcium nutrition from food in postmenopausal women is urgent issue, Dr Yoo Kyoung Park pointed out that our claim is still premature to apply to whole population. As Dr Y-K Park pointed out that the KNHANES study had been limited the age ( 50 years of age) of the participants and the findings about calcium insufficiency should not be expanded into entire population [1]. On the other hand, the National Nutrition Survey in Japan [2] was subjected community dwelling household (n ¼ 3507) including the people aged over 1 year. Therefore, the participants of this research consisted of entire generation of Japan. The report of the National Nutritional Survey in Japan indicated that the calcium intake in younger generation (420e454 mg/ day for age 20e40 years old) was less than postmenopausal women (568e546 mg/day for sixties and seventies). In addition, total caloric intake of younger generation (1706 and 1652 kcal/day for twenties and forties, respectively) and the postmenopausal women (1766 and 1639 kcal/day for sixties and seventies, respectively) were almost same level suggesting that the calcium density in foods (Calcium in mg/day/Caloric intake in k Cal) was around 30% less in the younger generation (0.25e0.27 mg/kcal) than those in the older generation (0.32e0.33 mg/kcal). As it was written in our article, the calcium intake in older generation was still far less from the calcium requirement (788 mg/day for old women or 0.48 mg/kcal) [3]. Therefore, the postmenopausal women, who had relatively high calcium intake, took calcium around 70% of requirement. Although there was no available data regarding the effect of calcium intake on the development of peak bone mass in a prospective study design in Asian population, the low calcium intake seen in a younger generation in Japan strongly suggested that the development of proper peak bone mass may not be achieved by the recent young generation in Japan. Bone health has been reported to improve in Vietnamese postmenopausal women, who were received nutritional education [4]. Therefore, re-education regarding calcium intake will be required for the younger population. On the other hand, since the older generation in Japan had been adapted to the traditional dietary custom, it may be difficult to increase in calcium intake from the foods, further. Thus, we propose to take calcium supplement for the older generation. Since bone mineralization abnormalities in VDR knock out mice was recovered by increasing calcium and phosphate intakes [5], intestinal calcium absorption is an essential factor to promote bone calcification rather than vitamin D. Thus, the insufficient intake of calcium seen in recent Japan may be critical in not only postmenopausal women but also in the younger generation, and that is why we emphasized our concern for all Japanese generation. The intestinal calcium absorption is higher in the people with habitually low calcium intake through active transport system by calcitriol especially in younger generation [6]. On the other hand, the intestinal adaptation for low calcium intake may not properly active in elderly people because of low production of 1,25(OH)2D in kidney [7]. Therefore, passive transport of calcium, which is facilitated by high calcium intake, may have a meaningful role on the bone metabolism in the older people. In addition to high calcium intake, vitamin D nutrition also plays an important role on bone health. As Dr. Yoo Kyoung Park pointed out properly, we could not present vitamin D nutritional status in our National Nutritional survey, because the research did not measure serum level of 25(OH)D in the participants. However, the survey was reported the vitamin D intake from food in the participants. The mean intake of vitamin D in the female participants age...

Recent nutritional trends of calcium and vitamin D in East Asia

Hiroaki Ohta,Kazuhiro Uenishi,Masataka Shiraki 대한골다공증학회 2016 Osteoporosis and Sarcopenia Vol.2 No.4

Abstract Calcium intake may play an important role on bone health. The recent national nutritional survey in Japan revealed the gradual decrease in calcium intake to around 480 mg/day. In addition, the patients with low level of vitamin D become too large in proportion. The present perspective proposes to increase calcium intake in Asian population.

FREE PAPAR ( ROOM 1 ) : A - 19 ; The Effect of Inhalation of Eosinophils on Bronchial Hyperresponsiveness

( T . Yamamoto,J . Chihara,H . Uenishi,D . Kurachi,S . Nakajima ) 대한천식 및 알레르기학회 ( 구 대한알레르기학회 ) 1991 한일합동심포지움 Vol.11 No.1

Introduction of the Treatment Center (the sewage disposal plant) system using Light weight and Compact X-band Fine radar Rain & Snow Gauge

Yuji Ohhigashi,DongSik Kim,Norihisa Uenishi 한국기상학회 2005 한국기상학회 학술대회 논문집 Vol.2005 No.-

Analyses of pig genomes provide insight into porcine demography and evolution

Groenen, Martien A. M.,Archibald, Alan L.,Uenishi, Hirohide,Tuggle, Christopher K.,Takeuchi, Yasuhiro,Rothschild, Max F.,Rogel-Gaillard, Claire,Park, Chankyu,Milan, Denis,Megens, Hendrik-Jan,Li, Sheng Nature Publishing Group, a division of Macmillan P 2012 Nature Vol.491 No.7424

For 10,000??years pigs and humans have shared a close and complex relationship. From domestication to modern breeding practices, humans have shaped the genomes of domestic pigs. Here we present the assembly and analysis of the genome sequence of a female domestic Duroc pig (Sus scrofa) and a comparison with the genomes of wild and domestic pigs from Europe and Asia. Wild pigs emerged in South East Asia and subsequently spread across Eurasia. Our results reveal a deep phylogenetic split between European and Asian wild boars ?? million years ago, and a selective sweep analysis indicates selection on genes involved in RNA processing and regulation. Genes associated with immune response and olfaction exhibit fast evolution. Pigs have the largest repertoire of functional olfactory receptor genes, reflecting the importance of smell in this scavenging animal. The pig genome sequence provides an important resource for further improvements of this important livestock species, and our identification of many putative disease-causing variants extends the potential of the pig as a biomedical model.

Immunophenotype Characterization for Swine Selected Line, Which is Resistant for the Mycoplasma Pneumonia

Katayama, Masafumi,Fukuda, Tomokazu,Okamuara, Toshihiro,Suda, Yoshihito,Suzuki, Eisaku,Uenishi, Hirohide,Suzuki, Keiichi Asian Australasian Association of Animal Productio 2011 Animal Bioscience Vol.24 No.7

Mycoplasma Pneumonia of swine (MPS) decreases the daily growth of pigs, and, co-infection with a virus sometimes causes severe pneumonia. Genetic selection of pigs resistant to the pulmonary MPS lesion might solve the economic loss due to MPS in animal production. Here, we examined the immunophenotype of Landrace line (Miyagino L2), genetically selected to reduce the incidence of pulmonary MPS lesion for 5 generations in Miyagi Prefecture Animal Industry Experiment Station. Although this line is expected to be resistant to the pulmonary MPS lesion, the biological characteristics of its immune function are not clear. We investigated details of the immunorelated phenotype of Miyagino L2 at the hematological and molecular biological level, including cytokine expression, and compared the results with that of non-genetically selected Landrace. Miyagino L2 showed decreased antigen-specific IgG and IgM production and increased CD8-positive T-cell population, and high levels of cortisol concentration, suggesting that the MPS-resistant phenotype is associated these immunological differences. Additionally, T-cell CD4 expression was highly correlated with the MPS expected breeding value. Although the detailed mechanisms underlying this high correlation remain unknown, our result suggested that the genetic selection of the expression level of CD4 might be useful to improve MPS resistance in pig production.

An Association Study of the Signal Transducer and Activator of Transcription 6 Gene With Periodic Psychosis

Seiya Kawashige,Tetsufumi Kanazawa,Atsushi Tsutsumi,Hiroki Kikuyama,Hiroyuki Uenishi,Jun Koh,Hiroshi Yoneda 대한신경정신의학회 2008 PSYCHIATRY INVESTIGATION Vol.5 No.1

Objective: Recent molecular and genetic investigations have suggested that the current nosology for major psychiatric disorders, based on the “two-entities-principal” is not accurate with respect to clinical observations; patient groups that do not fit to the current operative diagnostic boundaries are readily identified. We aimed to perform an investigation of the signal transducer and activator of transcription 6 (STAT6) gene (located on 12q13), which has an important role in the apoptotic cascade, with patients suffering from periodic psychosis. Methods: Genetic association study has been employed for the current work. Investigated six tag-SNPs were chosen from Hapmap database. Results: Among six tag-SNPs, one marker (rs10783813), located in the STAT6 gene, showed modest association (p<0.05), although no marker or haplotype block showed association after Bonferroni’s correction. Conclusion: Future studies will reveal the etiological role of STAT6, and of other genes of the apoptotic cascade, in major psychiatric disorders. Objective: Recent molecular and genetic investigations have suggested that the current nosology for major psychiatric disorders, based on the “two-entities-principal” is not accurate with respect to clinical observations; patient groups that do not fit to the current operative diagnostic boundaries are readily identified. We aimed to perform an investigation of the signal transducer and activator of transcription 6 (STAT6) gene (located on 12q13), which has an important role in the apoptotic cascade, with patients suffering from periodic psychosis. Methods: Genetic association study has been employed for the current work. Investigated six tag-SNPs were chosen from Hapmap database. Results: Among six tag-SNPs, one marker (rs10783813), located in the STAT6 gene, showed modest association (p<0.05), although no marker or haplotype block showed association after Bonferroni’s correction. Conclusion: Future studies will reveal the etiological role of STAT6, and of other genes of the apoptotic cascade, in major psychiatric disorders.

Increases in iPS Transcription Factor (Oct4, Sox2, c-Myc, and Klf4) Gene Expression after Modified Electroconvulsive Therapy

Masaki Nishiguchi,Hiroki Kikuyama,Tetsufumi Kanazawa,Atsushi Tsutsumi,Takao Kaneko,Hiroyuki Uenishi,Yasuo Kawabata,Seiya Kawashige,Jun Koh,Hiroshi Yoneda 대한신경정신의학회 2015 PSYCHIATRY INVESTIGATION Vol.12 No.4

ObjectiveaaElectroconvulsive therapy (ECT) is a reasonable option for intractable depression or schizophrenia, but a mechanism of action has not been established. One credible hypothesis is related to neural plasticity. Three genes (Oct4, Sox2, c-Myc) involved in the induction of induced pluripotent stem (iPS) cells are Wnt-target genes, which constitute a key gene group involved in neural plasticity through the TCF family. Klf4 is the other gene among Yamanaka’s four transcription factors, and increases in its expression are induced by stimulation of the canonical Wnt pathway. MethodsaaWe compared the peripheral blood gene expression of the four iPS genes (Oct4, Sox2, c-Myc, and Klf4) before and after modified ECT (specifically ECT with general anesthesia) of patients with intractable depression (n=6) or schizophrenia (n=6). Using Thymatron ten times the total bilateral electrical stimulation was evoked. ResultsaaBoth assessments of the symptoms demonstrated significant improvement after mECT stimulation. Expression of all four genes was confirmed to increase after initial stimulation. The gene expression levels after treatment were significantly different from the initial gene expression in all twelve cases at the following treatment stages: at the 3rd mECT for Oct4; at the 6th and 10th mECT for Sox2; and at the 3rd, 6th and 10th mECT for c-Myc. ConclusionaaThese significant differences were not present after correction for multiple testing; however, our data have the potential to explain the molecular mechanisms of mECT from a unique perspective. Further studie should be conducted to clarify the pathophysiological involvement of iPS-inducing genes in ECT.