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Verification of Autonomous Decentralized Control UPS system using FPGA based Hardware Controller
Tsuyoshi Saito,Nobuaki Doi,Tomoki Yokoyama 전력전자학회 2007 ICPE(ISPE)논문집 Vol.- No.-
Design concept of FPGA based hardware controller with HW/SW codesign for autonomous decentralized control UPS system is proposed. Progress of FPGA technology makes it possible to include the software macro CPU core into the FPGA chip, a high flexibility can be realized for the construction of the control processor in power electronics application. In the proposed method, all the control system is implemented in one FPGA chip. Complicated calculations are assigned to hardware calculation logic, and the parallel processing circuit makes it possible to realize minimizing the calculation time. Also Nios II CPU core is implemented in the same FPGA chip, and the software development can be applied for non-time critical calculations.The advantages of the proposed system is discussed through simulations and experiments.
Tsuyoshi Tokinaga,Takumi Yonezawa,Masateru Saito,Yoshifumi Morita,Hirofumi Tanabe,Balint Kiss 제어로봇시스템학회 2019 제어로봇시스템학회 국제학술대회 논문집 Vol.2019 No.10
The objective of the study involved developing a rehabilitation support robot for self-standing-up training of hemiplegic stroke patients to restore normal standing-up motion. Based on our previous analysis of the therapist"s guiding movements in standing-up training of patients, a passive-type robot was adopted. However, the link weight of the robot acts as a load at the patient’s waist. In this work, we designed a counterbalance mechanism for the robot in order to reduce the load at the patient’s waist and determined the optimal parameters for the mechanism. We confirmed by simulation that the specifications of the forces acting on the end-effectors of the robots were satisfied, and thus the proposed counterbalance mechanism was effective.
Monitoring of Desertification Using Spectral Information in Lnner Mongolia, China
Tsuyoshi Akiyama,Kensuke Kawamura,Ayumi Fukuo,Genya Saito,Zuozhong Cheng 한국초지조사료학회 2009 한국초지조사료학회 학술대회논문집 Vol.2009 No.08
Spectral measurement was applied to monitor degradation of steppe grassland in Inner Mongolia, China. Supply of drinking water for domestic animal is an important for nomadic peoples in Xilingol steppe. There is only one main drinking place (site-00) for animals at the center of Branch No.4 of Baiyinkulun Livestock Farm. So the distance from the village (site-00) can be used as an effective indicator for grazing intensity since the water tank in the village is the main drinking place for animals. In addition to the measurement of surface reflectance, vegetation surveys were carried out as a function of the distance from site-00 at every 1-㎞ interval to each four directions until the 5-㎞ point. It has cleared that the effects of grazing on vegetation mitigated according to the distance from site-00. Negative plant indicators of grazing intensity such as Stipa grandis increased in dominance with distance from site-00, whereas positive indicators of grazing intensity, such as Cleistogenens squarrosa decreased. Changes in growth parameters along the environmental gradients were reflected on NDVI (Normalized Difference Vegetation Index), in which NDVI was positively correlated with the aboveground biomass (r=0.77), plant height (r=0.69) and coverage (r=0.89), respectively. These results suggested that a spectral vegetation index is effective for the detection of the degradation in free grazing grassland.
Investigation of axial-injection end-burning hybrid rocket motor regression
Saito, Yuji,Yokoi, Toshiki,Neumann, Lukas,Yasukochi, Hiroyuki,Soeda, Kentaro,Totani, Tsuyoshi,Wakita, Masashi,Nagata, Harunori Techno-Press 2017 Advances in aircraft and spacecraft science Vol.4 No.3
The axial-injection end-burning hybrid rocket proposed twenty years ago by the authors recently recaptured the attention of researchers for its virtues such as no ${\zeta}$ (oxidizer to fuel mass ratio) shift during firing and good throttling characteristics. This paper is the first report verifying these virtues using a laboratory scale motor. There are several requirements for realizing this type of hybrid rocket: 1) high fuel filling rate for obtaining an optimal ${\zeta}$; 2) small port intervals for increasing port merging rate; 3) ports arrayed across the entire fuel section. Because these requirements could not be satisfied by common manufacturing methods, no previous researchers have conducted experiments with this kind of hybrid rocket. Recent advances in high accuracy 3D printing now allow for fuel to be produced that meets these three requirements. The fuel grains used in this study were produced by a high precision light polymerized 3D printer. Each grain consisted of an array of 0.3 mm diameter ports for a fuel filling rate of 98% .The authors conducted several firing tests with various oxidizer mass flow rates and chamber pressures, and analysed the results, including ${\zeta}$ history, using a new reconstruction technique. The results show that ${\zeta}$ remains almost constant throughout tests of varying oxidizer mass flow rates, and that regression rate in the axial direction is a nearly linear function of chamber pressure with a pressure exponent of 0.996.
A Meta-Analysis of Slow Pull versus Suction for Endoscopic Ultrasound-Guided Tissue Acquisition
( Yousuke Nakai ),( Tsuyoshi Hamada ),( Ryunosuke Hakuta ),( Tatsuya Sato ),( Kazunaga Ishigaki ),( Kei Saito ),( Tomotaka Saito ),( Naminatsu Takahara ),( Suguru Mizuno ),( Hirofumi Kogure ),( Kazuhi 대한소화기기능성질환·운동학회(구 대한소화관운동학회) 2021 Gut and Liver Vol.15 No.4
Background/Aims: Endoscopic ultrasound (EUS)-guided tissue acquisition is widely utilized as a diagnostic modality for intra-abdominal masses, but there remains debate regarding which suction technique, slow pull (SP) or conventional suction (CS), is better. A meta-analysis of reported studies was conducted to compare the diagnostic yields of SP and CS during EUS-guided tissue acquisition. Methods: We conducted a systematic electronic search using MEDLINE/PubMed, Web of Science, and the Cochrane Central Register of Controlled Trials to identify clinical studies comparing SP and CS. We meta-analyzed accuracy, sensitivity, blood contamination and cellularity using the random-effects model. Results: A total of 17 studies (seven randomized controlled trials, four prospective studies, and six retrospective studies) with 1,616 cases were included in the analysis. Compared to CS, there was a trend toward better accuracy (odds ratio [OR], 1.48; 95% confidence interval [CI], 0.97 to 2.27; p=0.07) and sensitivity (OR, 1.67; 95% CI, 0.95 to 2.93; p=0.08) with SP and a significantly lower rate of blood contamination (OR, 0.48; 95% CI, 0.33 to 0.69; p<0.01). However, there was no significant difference in cellularity between SP and CS, with an OR of 1.28 (95% CI, 0.68 to 2.40; p=0.45). When the use of a 25-gauge needle was analyzed, the accuracy and sensitivity of SP were significantly better than those of CS, with ORs of 4.81 (95% CI, 1.99 to 11.62; p<0.01) and 4.69 (95% CI, 1.93 to 11.40; p<0.01), respectively. Conclusions: Compared to CS, SP appears to provide better accuracy and sensitivity in EUSguided tissue acquisition, especially when a 25-gauge needle is used. (Gut Liver 2021;15:625- 633)
Koji Matsuo,Muneaki Shimada,Tsuyoshi Saito,Kazuhiro Takehara,Hideki Tokunaga,Yoh Watanabe,Yukiharu Todo,Kenichirou Morishige,Mikio Mikami,Toru Sugiyama 대한부인종양학회 2018 Journal of Gynecologic Oncology Vol.29 No.1
Objective: To examine the surgical-pathological predictors of para-aortic lymph node (PAN) metastasis at radical hysterectomy, and for PAN recurrence among women who did not undergo PAN dissection at radical hysterectomy. Methods: This is a retrospective analysis of a nation-wide cohort study of surgically-treated stage IB–IIB cervical cancer (n=5,620). Multivariate models were used to identify independent surgical-pathological predictors for PAN metastasis/recurrence. Results: There were 120 (2.1%) cases of PAN metastasis at surgery with parametrial involvement (adjusted odds ratio [aOR]=1.65), deep stromal invasion (aOR=2.61), ovarian metastasis (aOR=3.10), and pelvic nodal metastasis (single-node aOR=5.39 and multiple-node aOR=33.5, respectively) being independent risk factors (all, p<0.05). Without any risk factors, the incidence of PAN metastasis was 0.9%, while women exhibiting certain risk factor patterns (>20% of the study population) had PAN metastasis incidences of ≥4%. Among 4,663 clinically PAN-negative cases at surgery, PAN recurrence was seen in 195 (4.2%) cases that was significantly higher than histologically PAN-negative cases (2.5%, p=0.046). In clinically PAN-negative cases, parametrial involvement (adjusted hazard ratio [aHR]=1.67), lympho-vascular space invasion (aHR=1.95), ovarian metastasis (aHR=2.60), and pelvic lymph node metastasis (single-node aHR=2.49 and multiple-node aHR=8.11, respectively) were independently associated with increased risk of PAN recurrence (all, p<0.05). Without any risk factors, 5-year PAN recurrence risk was 0.8%; however, women demonstrating certain risk factor patterns (>15% of the clinically PAN-negative population) had 5-year PAN recurrence risks being ≥8%. Conclusion: Surgical-pathological risk factors proposed in this study will be useful to identify women with increased risk of PAN metastasis/recurrence.
Cervical conization with endoCUT mode applying gastrointestinal endoscopic polypectomy technique
Masato Tamate,Motoki Matsuura,Tsuyoshi Saito 대한산부인과학회 2023 Obstetrics & Gynecology Science Vol.66 No.6
Objective To show how endoCUT mode can be safely managed with cervical conization. Methods Demonstration of the technique and explanation of endoCUT and soft coagulation mode with narrated video footage. Cervical conization is a therapeutic and diagnostic procedure performed for the diagnosis of cervical intraepithelial lesions and cervical cancer. Specific methods include cold scalpel, ultrasonically activated device and laser, and loop electrosurgical excision procedure (LEEP), which involves transpiration and partial excision. The endoCUT mode and soft coagulation in VIO3® (ERBE, Tübingen, Germany) were used to perform cervical conical resection safely and at low cost. The endoCUT mode was originally developed for polypectomy in gastrointestinal endoscopy, where no counter traction can be applied. Results The endoCUT mode approach to cervical conization with several key strategies to minimize blood loss and ensure safety: 1) incisions can be made in close contact; 2) resection can be performed with minimal contact with the lesion; 3) control of bleeding from the resected transection by soft coagulation; and 4) low running cost of endoCUT mode. Conclusion Conventionally, cervical conical resection has been performed by using a device capable of making a close incision (cold scalpel, ultrasonically activated device and laser, and LEEP etc.), but there have been issues with bleeding control and cost. Here, we present a new technique using the endoCUT mode and several strategies for safe and effective resection.
Foxf2 represses bone formation via Wnt2b/β-catenin signaling
Tanaka Tomoyuki,Takahashi Akira,Kobayashi Yutaka,Saito Masanori,Xiaolong Sun,Jingquan Chen,Ito Yoshiaki,Kato Tsuyoshi,Ochi Hiroki,Sato Shingo,Yoshii Toshitaka,Okawa Atsushi,Carlsson Peter,Inose Hiroyu 생화학분자생물학회 2022 Experimental and molecular medicine Vol.54 No.-
Differentiation of mesenchymal stem cells (MSCs) into osteoblasts is a critical process for proper skeletal development and acquisition/maintenance of bone mass. However, since this regulatory mechanism has not yet been fully elucidated, the treatment of severe osteoporosis and fractures is a challenge. Here, through a comprehensive analysis of gene expression during the differentiation of MSCs into osteoblasts, we show that the forkhead transcription factor Foxf2 is a crucial regulator of this process. Foxf2 expression transiently increased during MSC osteoblastic differentiation. Overexpression of Foxf2 in MSCs inhibited osteoblastic differentiation, and conversely, knockdown of Foxf2 expression promoted this process. Osteoprogenitor-specific Foxf2 knockout mice developed a high bone mass phenotype due to increased bone formation. RNA-seq analysis and molecular experiments revealed that Foxf2 regulation of bone formation is mediated by Wnt2b. Knockdown of Foxf2 in mouse femurs enhanced bone regeneration in vivo. FOXF2 expression was correlated with hip bone mineral density in postmenopausal women with low bone mass. Finally, inhibition of FOXF2 promoted osteoblastic differentiation of human MSCs. This study uncovers a critical role of Foxf2 in the differentiation of MSCs into osteoblasts and provides insight into the pathogenesis associated with bone-related diseases such as osteoporosis and nonunion after fracture