Addendum: A phase II trial of cytoreductive surgery combined with niraparib maintenance in platinum- sensitive, secondary recurrent ovarian cancer: SGOG SOC-3 study

Ting-Yan Shi,Libing Xiang,Jianqing Zhu,Ji-hong Liu,Ping Zhang,Hua-ying Wang,Yanling Feng,Tao Zhu,Yingli Zhang,Aijun Yu,Wei Jiang,Xipeng Wang,Yaping Zhu,Sufang Wu,Yincheng Teng,Jiejie Zhang,Rong Jiang 대한부인종양학회 2022 Journal of Gynecologic Oncology Vol.33 No.4

c-MES 적용을 위한 시스템 엔지니어링 방법론에 관한 연구

SHI TING,정연경(Youn-Kyoung Joung),노상도(Sang Do Noh),조현제(Hyun Jei Jo),조용주(Yong Ju Jo),최석우(Seog Ou Choi) 한국경영과학회 2012 한국경영과학회 학술대회논문집 Vol.2012 No.5

최근 제조업은 치열해지는 경쟁 시장환경 속에서 경쟁력 확보를 위해 생산정보화에 많이 투자를 하고 있다. 대기업과 마찬가지로 중소제조기업에서도 생산성 향상과 납기 준수 등을 위하여 체계화된 생산일정계획 수립 및 생산실적의 실시간 피드백을 지원할 수 있는 제조실행시스템 (Manufacturing Execution System, MES)의 도입이 필요하다. 그러나 특히 중소제조기업의 제조실행 시스템 적용 시 정형화된 구축 프로세스가 없으며, 특정 업종 위주로 적용 범위가 한정되어 있어 모든 제조기업에서 효과적으로 구축하고 활용할 수 없는 실정이다. 제조실행시스템의 효율적인 보급과 도입을 위해서는 제조기업별로 다양한 생산환경의 특성이 반영된 생산정보화로 추진할 수 있는 맞춤형 제조실행시스템 도입 방법론과 적용 절차를 정립하는 것이 필요하다. 본 논문에서는 우리나라 중소제조기업을 대상으로 맞춤형제조실행시스템을 효율적으로 도입, 구축하기 위한 도입 방법과 절차를 시스템 엔지니어링 방법론을 기반으로 연구하였다.

MRI T2-Weighted Imaging and Fat-Suppressed T2-Weighted Imaging Image Fusion Technology Improves Image Discriminability for the Evaluation of Anal Fistulas

Shi-Ting Feng,Mengqi Huang,Zhi Dong,Ling Xu,Yin Li,Yingmei Jia,Huasong Cai,Bingqi Shen,Zi-Ping Li 대한영상의학회 2019 Korean Journal of Radiology Vol.20 No.3

Objective: To explore whether MRI fusion technology (combined T2-weighted imaging [T2WI] and fat-suppressed T2WI [T2WI-FS]) improves signal differences between anal fistulas and surrounding structures. Materials and Methods: A total of 32 patients with confirmed diagnoses of anal fistula were retrospectively studied. All available T2WI and T2WI-FS images for each patient were used to generate fusion image (T2WI-Fusion) based on the addition of gray values obtained from each pixel via an MR post-processing work station. The discriminability of fistula, perianal sphincter, and perianal fat in T2WI, T2WI-FS, and T2WI-Fusion images was quantified with Fisher’s scoring algorithm. For subjective visual image assessment by researchers, five-point scale scores were determined using a modified double-stimulus continuous qualityscale test to evaluate T2WI-FS, T2WI, enhanced axial three-dimensional-volumetric interpolated breath-hold examination (3D-VIBE), and T2WI-Fusion sequence images. The differences were subsequently compared. Results: Mean Fisher scores for fistulas vs. sphincters obtained from T2WI-Fusion (FFusion-fistula = 6.56) were significantly higher than those from T2WI (FT2WI-fistula = 3.35) (p = 0.001). Mean Fisher scores for sphincters vs. fat from T2WI-Fusion (FFusion-sphincter = 10.84) were significantly higher than those from T2WI-FS (FSFS-sphincter = 2.57) (p = 0.001). In human assessment, T2WI-Fusion showed the same fistula discriminability as T2WI-FS, and better sphincter discriminability than T2WI. Overall, T2WI-Fusion showed better discriminability than T2WI, T2WI-FS, and enhanced 3D-VIBE images. Conclusion: T2WI and T2WI-FS fusion technology improves signal differences between anal fistulas and surrounding structures, and may facilitate better evaluation of anal fistulas and sphincters.

제조시스템의 모델링과 시뮬레이션을 이용한 MES 도입방안 및 효과 사전 분석에 관한 연구

SHI TING,ZHAO WENBIN,이주형(Joohyeong Lee),박승현(Seunghyun Park),노상도(Sang Do Noh) (사)한국CDE학회 2014 한국 CAD/CAM 학회 학술발표회 논문집 Vol.2014 No.2

Many manufacturing companies are investing in a lot of the information system to improve the competitiveness. To share information quickly between an enterprise"s information systems and support to decision-making, obtain and process information quickly and manage it efficiently and comprehensively on the production floor, Manufacturing Execution System (MES) has been introduced to the manufacturing companies. However, because each company has the different production environment, some companies haven’t obtained many effects after applying the MES system. So many minor enterprises do not to introduce the MES. This study was put forward the method of analysis the introduction methodology and effect of MES using modeling and simulation before an enterprise introduce the MES.

시스템 엔지니어링 기반의 중소제조기업 MES 적용 절차에 관한 연구

SHI TING,정연경(Youn-Kyoung Joung),노상도(Sang Do Noh),조현제(Hyun Jei Jo),조용주(Yong Ju Jo),최석우(Seog Ou Choi) (사)한국CDE학회 2012 한국 CAD/CAM 학회 학술발표회 논문집 Vol.2012 No.2

최근 제조업은 치열해지는 경쟁 시장환경 속에서 경쟁력 확보를 위해 생산정보화에 많이 투자를 하고 있다. 대기업과 마찬가지로 중소제조기업에서도 생산성 향상과 납기 준수 등을 위하여 체계화된 생산일정계획 수립 및 생산실적의 실시간 피드백을 지원할 수 있는 제조실행시스템(Manufacturing Execution System, MES)의 도입이 필요하다. 그러나 특히 중소제조기업의 제조실행시스템 적용 시 정형화된 구축 프로세스가 없으며, 특정 업종 위주로 적용 범위가 한정되어 있어 모든 제조기업에서 효과적으로 구축하고 활용할 수 없는 실정이다. 제조실행시스템의 효율적인 보급과 도입을 위해서는 제조기업별로 다양한 생산환경의 특성이 반영된 생산정보화로 추진할 수 있는 일반적인 MES 도입 방법론과 적용 절차를 정립하는 것이 필요하다. 본 논문에서는 우리나라 중소제조기업을 대상으로 제조실행시스템을 효율적으로 도입, 구축하기 위한 도입 방법과 절차를 시스템엔지니어링 방법론을 기반으로 연구하였다.

자동차 차체공장 웹 기반 공간 및 물류 자동분석 시스템

SHI TING,박양호(Yang Ho Park),전찬모(Chan Mo Jun),노상도(Sang Do Noh),전유빈(Yoo Bin Jeon) (사)한국CDE학회 2013 한국 CAD/CAM 학회 학술발표회 논문집 Vol.2013 No.1

As global competit ions among automotive manufacturers become more and more severe, automotive companies are paying a lot of efforts in large product mix and mult i-batch production to satisfy the consumer’s demands. Most automotive co mpanies try to take adv antage of modeling and simulat ion technologies to realize “ front-loading” of engineering problems in very early stage of product development and production. However, the modeling and simulation is difficult for someone who is not a simulat ion expert, and generally it is expensive and time-consuming to collect and analyze data, make, verify and validate a model. Also, it is very difficult to reflect the changes in the factory for reliable simulations. In this research, we define the standard process and templates for material flow and area analysis of automotive body assembly shops. And a method of automated generation of simulation model using Autodesk and Technomatix is suggested and implemented. The results of this research were applied into body assembly shops of a Korean automotive company, and the results and benefits were explained in this paper.

A phase II trial of cytoreductive surgery combined with niraparib maintenance in platinum-sensitive, secondary recurrent ovarian cancer: SGOG SOC-3 study

Ting-Yan Shi,Sheng Yin,Jianqing Zhu,Ping Zhang,Jihong Liu,Libing Xiang,Yaping Zhu,Sufang Wu,Xiaojun Chen,Xipeng Wang,Yin-Cheng Teng,Tao Zhu,Aijun Yu,Yingli Zhang,Yanling Feng,He Huang,Wei Bao,Yanli Li 대한부인종양학회 2020 Journal of Gynecologic Oncology Vol.31 No.3

Background: In China, secondary cytoreductive surgery (SCR) has been widely used in ovarian cancer (OC) over the past two decades. Although Gynecologic Oncology Group-0213 trial did not show its overall survival benefit in first relapsed patients, the questions on patient selection and effect of subsequent targeting therapy are still open. The preliminary data from our pre-SOC1 phase II study showed that selected patients with second relapse who never received SCR at recurrence may still benefit from surgery. Moreover, poly(ADP-ribose) polymerase inhibitors (PARPi) maintenance now has been a standard care for platinum sensitive relapsed OC. To our knowledge, no published or ongoing trial is trying to answer the question if patient can benefit from a potentially complete resection combined with PARPi maintenance in OC patients with secondary recurrence. Methods: SOC-3 is a multi-center, open, randomized, controlled, phase II trial of SCR followed by chemotherapy and niraparib maintenance vs chemotherapy and niraparib maintenance in patients with platinum-sensitive second relapsed OC who never received SCR at recurrence. To guarantee surgical quality, if the sites had no experience of participating in any OC-related surgical trials, the number of recurrent lesions evaluated by central-reviewed positron emission tomography–computed tomography image shouldn't be more than 3. Eligible patients are randomly assigned in a 1:1 ratio to receive either SCR followed by 6 cycles of platinum-based chemotherapy and niraparib maintenance or 6 cycles of platinum-based chemotherapy and niraparib maintenance alone. Patients who undergo at least 4 cycles of chemotherapy and must be, in the opinion of the investigator, without disease progression, will be assigned niraparib maintenance. Major inclusion criteria are secondary relapsed OC with a platinum-free interval of no less than 6 months and a possibly complete resection. Major exclusion criteria are borderline tumors and non-epithelial ovarian malignancies, received debulking surgery at recurrence and impossible to complete resection. The sample size is 96 patients. Primary endpoint is 12-month non-progression rate. Trial Registration: ClinicalTrials.gov Identifier: NCT03983226

c-MES 적용을 위한 시스템 엔지니어링 방법론에 관한 연구

SHI TING,정연경(Youn-Kyoung Joung),노상도(Sang Do Noh),조현제(Hyun Jei Jo),조용주(Yong Ju Jo),최석우(Seog Ou Choi) 대한산업공학회 2012 대한산업공학회 춘계학술대회논문집 Vol.2012 No.5

최근 제조업은 치열해지는 경쟁 시장환경 속에서 경쟁력 확보를 위해 생산정보화에 많이 투자를 하고 있다. 대기업과 마찬가지로 중소제조기업에서도 생산성 향상과 납기 준수 등을 위하여 체계화된 생산일정계획 수립 및 생산실적의 실시간 피드백을 지원할 수 있는 제조실행시스템 (Manufacturing Execution System, MES)의 도입이 필요하다. 그러나 특히 중소제조기업의 제조실행 시스템 적용 시 정형화된 구축 프로세스가 없으며, 특정 업종 위주로 적용 범위가 한정되어 있어 모든 제조기업에서 효과적으로 구축하고 활용할 수 없는 실정이다. 제조실행시스템의 효율적인 보급과 도입을 위해서는 제조기업별로 다양한 생산환경의 특성이 반영된 생산정보화로 추진할 수 있는 맞춤형 제조실행시스템 도입 방법론과 적용 절차를 정립하는 것이 필요하다. 본 논문에서는 우리나라 중소제조기업을 대상으로 맞춤형제조실행시스템을 효율적으로 도입, 구축하기 위한 도입 방법과 절차를 시스템 엔지니어링 방법론을 기반으로 연구하였다.

민국시기 연변지역에 있어서의 통역양성학교 - 설립경위를 중심으로 -

김정실 ( Jin Ting Shi ) 한국일어일문학회 2020 日語日文學硏究 Vol.114 No.-

연변의 지리적 위치와 정치적 상황의 특성으로 이 지역을 둘러싸고 역사적으로 다양한 역학적인 움직임이 있었다. 본 연구에서는 연변조선족자치주 당안관에 소장된 역사자료를 활용하여 외국어 야반(夜班) 연구소와 한국역재소(譯才所)에 대한 분석을 통해 그 실태를 조사하여 객관적 역사사실에 접근하였다. 민 국(民國)측은 1914년 11 월에 통역사를 양성하는 외국어야반(夜班)연구소를 설립하고 일본어, 러시아어, 한국어를 가르쳤으며 1916 년에는 한국어역재소(譯才所)를 설립하여 조선어, 국문, 일본어를 가르쳤고 졸업생들은 연길현기관(機關) 에 등록되었다. 이와같이 민국(民國)측은 당시 복잡한 정치지리적상황으로 보다 적극적으로 통역사 양성학교를 설립하여 국내 정치안정을 도모하려고 했다는 점을 본 연구를 통하여 규명하였다. The geographical location and political situation made a great significance to Yanbian region. In this study, I tried to explore the actual condition by analyzing the history of the Evening School of Foreign Language and the Korean Translation Center, consulting the files of the Archives of Yanbian, Korean Autonomous Prefecture. In november 1914, the Republic of China established the Evening School of Foreign Language, which trained interpreters, and taught Japanese, Russian and Korean. In 1916, the Republic of China established the Korean Translation Center, which taught Korean, Chinese and Japanese, and graduates worked in the institutions of the prefectures of Yanjidao. Thus, this study revealed that the Republic of China actively established the school of interpretation at that time to achieve the political stability.

Moth-Flame Optimization-Based Maximum Power Point Tracking for Photovoltaic Systems Under Partial Shading Conditions

Shi, Ji-Ying,Zhang, Deng-Yu,Xue, Fei,Li, Ya-Jing,Qiao, Wen,Yang, Wen-Jing,Xu, Yi-Ming,Yang, Ting The Korean Institute of Power Electronics 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.5

This paper presents a moth-flame optimization (MFO)-based maximum power point tracking (MPPT) method for photovoltaic (PV) systems. The MFO algorithm is a new optimization method that exhibits satisfactory performance in terms of exploration, exploitation, local optima avoidance, and convergence. Therefore, the MFO algorithm is quite suitable for solving multiple peaks of PV systems under partial shading conditions (PSCs). The proposed MFO-MPPT is compared with four MPPT algorithms, namely the perturb and observe (P&O)-MPPT, incremental conductance (INC)-MPPT, particle swarm optimization (PSO)-MPPT and whale optimization algorithm (WOA)-MPPT. Simulation and experiment results demonstrate that the proposed algorithm can extract the global maximum power point (MPP) with greater tracking speed and accuracy under various conditions.