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Nguyen Le Minh Tri,김지태,Bach Long Giang,T.M. Al Tahtamouni,Pham Thi Huong,이창하,Nguyen Minh Viet,Do Quang Trung 한국공업화학회 2019 Journal of Industrial and Engineering Chemistry Vol.80 No.-
In this study a novel Ag-doped graphitic carbon nitride (g-C3N4) photocatalyst was synthesized and appliedas high efficientmaterial under solarlight towardsemerging antibiotic pollutantin hospital wastewater. Thetetracycline (TC) was chosen as a target pollutant and the content of Ag doping at 3 mmol revealed thehighest photocatalytic degradation efficiency of TC (96.8%) after 120 min under solar light irradiation. Thephotoluminescence and UV–vis analysis confirmed the enhancement of charge separation and transfer inthe graphitic carbon structure after Ag-doping. The removal efficiency of TC using g-C3N4 and Ag-doped g-C3N4 (AgCN) underdark conditions was only 25.6 and 31.8%, respectively. While under solarlight conditions,the removal efficiency of TC increased to 68.3 and 96.8% for g-C3N4 and AgCN, respectively. The reusabilityprocess showed that AgCN displayed extremely high stability after 6 cycles without significant drop inantibiotic degradation efficiency. The application of AgCN was tested for treatment of TC from hospitalwastewater and it showed high removal efficiency of 89.6% within 120 min reaction time. In addition, theintermediatesgeneratedandreductionof total organiccarbon(TOC)duringthephotocatalyticreactionweredetected to support information of possible TC removal mechanism.
( Nguyen Thai Son ),( Vu Thi Thu Huong ),( Vu Thi Kim Lien ),( Do Thi Quynh Nga ),( Tran Thi Hai Au ),( Tang Thi Nga ),( Le Nguyen Minh Hoa ),( Tran Quang Binh ) 한국미생물생명공학회(구 한국산업미생물학회) 2019 Journal of microbiology and biotechnology Vol.29 No.9
The extensive distribution of multidrug-resistant (MDR) methicillin-resistant Staphylococcus aureus (MRSA) poses a threat to healthcare worldwide. This study aimed to investigate the MDR and molecular patterns of MRSA isolates in children admitted to the two biggest tertiary care pediatric hospitals in northern and southern Vietnam. A total of 168 MRSA strains were collected to determine antibiotic susceptibility by minimum inhibitory concentration tests. Antibiotic-resistant genes, pulsed-field gel electrophoresis, staphylococcal cassette chromosome mec (SCCmec) typing, and multilocus sequence typing were used for the molecular characterization of MRSA. Among the total strains, the MDR rate (51.8%) was significantly higher in the northern hospital than in the southern hospital (73% vs. 39%, p < 0.0001). The MDR-MRSA with the highest rates were “ciprofloxacin-erythromycin-gentamicin-tetracyclines” (35.6%), followed by “erythromycin-tetracycline-chloramphenicol” (24.1%), and “ciprofloxacin-erythromycin-gentamicin” (19.5%), showing an accumulative total of 79.3%. The most susceptible antibiotics were rifampicin (100%) and vancomycin (100%), followed by doxycycline (94.0%), meropenem (78.0%), and cefotaxime (75.0%). The SCCmecII strains showed greater resistance to gentamicin, ciprofloxacin, tetracycline, meropenem and cephalosporins compared with the other strains. The SCCmecII strains exhibited the highest rate in the tested genes (aacA/aphD: 55.2%, ermA/B/C: 89.7%, and tetK/M: 82.8%). ST5-SCCmecII was the predominant clone in the northern hospital, whereas SCCmecIVa was more pronounced in the southern hospital. In conclusion, our results raised concerns about the predominant MDR-MRSA strains in the pediatric hospitals in Vietnam. The north-south difference in the antibiotic resistance patterns and genetic structure of MRSA suggests different MRSA origins and various uses of antimicrobial agents between the two regions.
EXISTENCE THEOREMS FOR CRITICAL DEGENERATE EQUATIONS INVOLVING THE GRUSHIN OPERATORS
Huong Thi Thu Nguyen,Tri Minh Nguyen Korean Mathematical Society 2023 대한수학회논문집 Vol.38 No.1
In this paper we prove the existence of nontrivial weak solutions to the boundary value problem -G<sub>1</sub>u = u<sup>3</sup> + f(x, y, u) in Ω, u ≥ 0 in Ω, u = 0 on ∂Ω, where Ω is a bounded domain with smooth boundary in ℝ<sup>3</sup>, G<sub>1</sub> is a Grushin type operator, and f(x, y, u) is a lower order perturbation of u<sup>3</sup> with f(x, y, 0) = 0. The nonlinearity involved is of critical exponent, which differs from the existing results in [11, 12].
NGUYEN, Thi Minh Thu,NGUYEN, Thi Tuong Anh,NGUYEN, Thi Thuy Vinh,PHAM, Huong Giang Korea Distribution Science Association 2021 The Journal of Asian Finance, Economics and Busine Vol.8 No.3
Using a multinomial logit model with the panel-data set of Vietnam manufacturing firms, this paper investigates the impacts of foreign direct investment (FDI) - small and medium enterprises (SMEs) linkages and other factors on SMEs' participation in the global value chain (GVC). We consider GVC firms are those engaging in any of the three modes including (i) using domestic inputs to export (D2E), (ii) using imported inputs to produce for the domestic market (I2P), (iii) using imported inputs to export (I2E). We discover that FDI-SME linkages statistically encourage Vietnamese SMEs to integrate into the GVC via I2P and I2E, while no statistical association between FDI-SME linkage and D2E participation is found. GVCs participation likelihood is also positively correlated with the introduction of new product introduction. The establishment of firms' production facilities in industrial zones and foreign ownership are both reported to be significantly decisive factors to SMEs' decisions on GVC participation. Besides, there is a strong association between firms' attributes, i.e. employment, capital intensity as well as financial access, and their participation in the GVC. Local governance quality (proxied by the Provincial Competitiveness Index) and the share of skilled labor at the province-level can facilitate firms' integration into GVCs, while greater market concentration may be a hurdle to such potential.
Nguyen, Huong Thi Thanh,Balaji, Nagarajan,Park, Cheolmin,Triet, Nguyen Minh,Le, Anh Huy Tuan,Lee, Seunghwan,Jeon, Minhan,Oh, Donhyun,Dao, Vinh Ai,Yi, Junsin Institute of Physics 2017 Semiconductor science and technology Vol.32 No.2
<P>Excellent surface passivation and anti-reflection properties of double-stack layers is a prerequisite for high efficiency of n-type c-Si solar cells. The high positive fixed charge (<I>Q</I> <SUB>f</SUB>) density of N-rich hydrogenated amorphous silicon nitride (a-SiN<SUB>x</SUB>:H) films plays a poor role in boron emitter passivation. The more the refractive index (<I> <B>n</B> </I>) of a-SiN<SUB>x</SUB>:H is decreased, the more the positive <I>Q</I> <SUB>f</SUB> of a-SiN<SUB>x</SUB>:H is increased. Hydrogenated amorphous silicon oxynitride (SiON) films possess the properties of amorphous silicon oxide (a-SiO<SUB>x</SUB>) and a-SiN<SUB>x</SUB>:H with variable <I> <B>n</B> </I> and less positive <I>Q</I> <SUB>f</SUB> compared with a-SiN<SUB>x</SUB>:H. In this study, we investigated the passivation and anti-reflection properties of Al<SUB>2</SUB>O<SUB>3</SUB>/SiON stacks. Initially, a SiON layer was deposited by plasma enhanced chemical vapor deposition with variable <I> <B>n</B> </I> and its chemical composition was analyzed by Fourier transform infrared spectroscopy. Then, the SiON layer was deposited as a capping layer on a 10 nm thick Al<SUB>2</SUB>O<SUB>3</SUB> layer, and the electrical and optical properties were analyzed. The SiON capping layer with <I> <B>n</B> </I>?=?1.47 and a thickness of 70 nm resulted in an interface trap density of 4.74?=?10<SUP>10</SUP> cm<SUP>−2</SUP> eV<SUP>−1</SUP> and <I>Q</I> <SUB>f</SUB> of −2.59?=?10<SUP>12</SUP> cm<SUP>−2</SUP> with a substantial improvement in lifetime of 1.52 ms after industrial firing. The incorporation of an Al<SUB>2</SUB>O<SUB>3</SUB>/SiON stack on the front side of the n-type solar cells results in an energy conversion efficiency of 18.34% compared to the one with Al<SUB>2</SUB>O<SUB>3</SUB>/a-SiN<SUB>x</SUB>:H showing 17.55% efficiency. The short circuit current density and open circuit voltage increase by up to 0.83 mA cm<SUP>−2</SUP> and 12 mV, respectively, compared to the Al<SUB>2</SUB>O<SUB>3</SUB>/a-SiN<SUB>x</SUB>:H stack on the front side of the n-type solar cells due to the good anti-reflection and front side surface passivation.</P>
Nguyen, Thanh Huong,Nguyen, Trung Kien,Kim, Bao Giang,Hoang, Van Minh,Phan, Thi Hai,Doan, Thu Huyen,Luong, Ngoc Khue,Nguyen, Thuy Linh,Nguyen, Tuan Lam,Pham, Thi Quynh Nga Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.no.sup1
Studies have shown that smoking is a learnt behavior, often initiated during adolescence. This paper aims to describe tobacco-related knowledge, attitude and associations among school adolescents aged 13-15 with exposure to anti-smoking information. Using data from the Global Youth Tobacco Survey (GYTS) in Viet Nam, 2014, knowledge was measured through 4 questions about tobacco use, and attitude was assessed through 3 questions on personal, social and environmental aspects. Students giving most anti-tobacco responses to all questions were considered as having correct knowledge or appropriate attitude or both. Access to anti-smoking information was determined by exposure to any media messages on tobacco control during the past 30 days and teaching in school about the danger of tobacco use during the past 12 months. A substantial percentage of students thought that being near others who smoke might be harmful to them and smoking is harmful to health (89.4% and 89.6% respectively). However, only 46.4% reported that it is definitely difficult to quit smoking and 66.9% thought that smoking for only 1 or 2 years, once stopped, is harmful to health. Slightly more than half of the respondents reported appropriate attitude that young smokers have fewer friends than others and smoking makes them less attractive and less comfortable at social events. Noticing anti-smoking messages in the media together with having lessons in school about the dangers of tobacco substantially increased the likelihood of having correct knowledge, appropriate attitude and both. Despite relatively high awareness about smoking harms, effective educational communication is still highly needed to improve the level of comprehensive knowledge and an appropriate attitude regarding tobacco use.
Artocarpus nigrifolius: Cytotoxic and Antibacterial Constituents
Tran Minh Hoi,김영호,Ha Van Anh,Nguyen Thi Thanh Huong,Nguyen Van Tuyen,Le Thi Tu Anh,Nguyen Thanh Tra,Ba Thi Cham,Nguyen Thi Thu Ha,Pham Thuy Linh,Doan Duy Tien,Phan Van Kiem,Ninh Khac Ban,Lidziya Kukha 한국응용생명화학회 2013 Applied Biological Chemistry (Appl Biol Chem) Vol.56 No.6
Six known compounds including α-amyrin 3-acetate (1), β-sitosterol (2), betulinic acid (3), friedelan-3-one (4),artochamin B (5), and 2-C-methyl-D-erythritol 4-O-α-D-glucopyranoside (6) were isolated from the stem barks and leaves of Artocarpus nigrifolius (Moraceae) for the first time. Their structures were identified by spectroscopic methods as well as comparison with literatures. Cytotoxicity and antibacterial activity of 1-6 were evaluated. Results showed that artochamin B (5)possessed the highest cytotoxicity towards MCF7, Lu, HepG2,and KB cell lines with IC50 values of 4.59, 20.00, 3.60, and 1.18μg/mL, respectively. It also inhibited the growth of Gram-positive bacteria (Bacillus subtilis, Staphylococcus aureus), whereas inactive on the growth of both Gram-negative bacteria and yeast.
( Hai Thi Nguyen ),( Huong Lan Nguyen ),( Minh Hong Nguyen ),( Thao Kim Nu Nguyen ),( Hang Thuy Dinh ) 한국미생물 · 생명공학회 2020 Journal of microbiology and biotechnology Vol.30 No.7
Acid mine drainage (AMD) has been a serious environmental issue that threatens soil and aquatic ecosystems. In this study, an acid-tolerant sulfate-reducing bacterium, strain S4, was isolated from the mud of an AMD storage pond in Vietnam via enrichment in anoxic mineral medium at pH 5. Comparative analyses of sequences of the 16S rRNA gene and dsrB gene involved in sulfate reduction revealed that the isolate belonged to the genus Desulfovibrio, and is most closely related to Desulfovibrio oxamicus (with 99% homology in 16S rDNA sequence and 98% homology in dsrB gene sequence). Denaturing gradient gel electrophoresis (DGGE) analyses of dsrB gene showed that strain S4 represented one of the two most abundant groups developed in the enrichment culture. Notably, strain S4 was capable of reducing sulfate in low pH environments (from 2 and above), and resistance to extremely high concentration of heavy metals (Fe 3,000 mg/l, Zn 100 mg/l, Cu 100 mg/ l). In a batch incubation experiment in synthetic AMD with pH 3.5, strain S4 showed strong effects in facilitating growth of a neutrophilic, metal sensitive Desulfovibrio sp. strain SR4H, which was not capable of growing alone in such an environment. Thus, it is postulated that under extreme conditions such as an AMD environment, acid- and metal-tolerant sulfate-reducing bacteria (SRB)- like strain S4 would facilitate the growth of other widely distributed SRB by starting to reduce sulfate at low pH, thus increasing pH and lowering the metal concentration in the environment. Owing to such unique physiological characteristics, strain S4 shows great potential for application in sustainable remediation of AMD.
Vo Minh Hoang Do,Long Giang Bach,Diem-Huong Nguyen Tran,Van Du Cao,Thi Nhu Quynh Nguyen,Duc Thuan Hoang,Van Cuong Ngo,Dai Hai Nguyen,Thai Thanh Hoang Thi 한국생물공학회 2020 Biotechnology and Bioprocess Engineering Vol.25 No.2
Polyamidoamine (PAMAM) dendrimer is emerging as an effective nanocarrier for delivering anticancer drugs. Still, unmodified PAMAM dendrimer is hardly used in vivo because of unsatisfied drug release, high tendency of interfering with cellular membranes, and rapid clearance by reticuloendothelial system. In this study, low generation polyamidoamine (PAMAM) dendrimer G3.0 is developed and surface modified with methoxypolyethylene glycol (PAMAM G3.0-mPEG) to overcome its limitations. Specifically, PAMAM G3.0 conjugated with mPEG at different ratios are investigated to effectively eliminate its charge-associated toxicity, in which PAMAM G3.0-mPEG- 8 is chosen for oxaliplatin (OX) loading. Results reveal that OX-loaded PAMAM G3.0-mPEG-8 has desirable size, good entrapment efficiency, and sustained release with minimum drug leakage. In addition, Resazurin assay indicates that the toxicity of loaded OX is reduced as compared to free drug but still maintain substantially anticancer activity on HeLa cells, suggesting the potential application of PAMAM G3.0-mPEG-8 for OX delivery in cancer therapy.