The Gene Polymorphism of VMAT2 Is Associated with Risk of Schizophrenia in Male Han Chinese

Hongying Han,Xiaowei Xia,Huirong Zheng,Chongbang Zhao,Yanming Xu,Jiong Tao,Xianglan Wang 대한신경정신의학회 2020 PSYCHIATRY INVESTIGATION Vol.17 No.11

Objective To investigate the association between gene polymorphism of vesicular monoamine transporter type 2(VMAT2) and schizophrenia in Han Chinese population.Methods 430 patients with schizophrenia and 470 age-sex matched controls were recruited from four mental health centers. All patients were diagnosed by two psychiatrists based on the Structured Clinical Interview for DSM Disorders (SCID). The ligase detection reactions (LDR) method was used to assess the polymorphism of the two SNPs (rs363371 and rs363324) of VMAT2.Results No associations of two SNPs with schizophrenia was found. When we stratified males and females for the analysis, we found that that in the recessive model of rs363371, there was an obvious significant association between rs363371 and schizophrenia in males (OR=0.564, 95% CI=0.357–0.892, p=0.014) but not females. For the association between rs363324 and schizophrenia, no association was found in either males or females. No association was found when stratifying early-onset schizophrenia and late-onset schizophrenia.Conclusion Our findings indicate that both rs363371 and rs363324 were not associated with schizophrenia, while it seemed that the AA genotype of rs363371 plays a protective effect in male Chinese in developing schizophrenia.

Higgs bosons from top quark decays

Han, Tao,Ruiz, Richard American Physical Society 2014 PHYSICAL REVIEW D - Vol.89 No.7

Non-decoupling MSSM Higgs sector and light superpartners

Han, Tao,Li, Tong,Su, Shufang,Wang, Lian-Tao Springer-Verlag 2013 Journal of high energy physics Vol.2013 No.11

Doping palladium with tellurium for the highly selective electrocatalytic reduction of aqueous CO ₂ to CO

Tao, Hengcong,Sun, Xiaofu,Back, Seoin,Han, Zishan,Zhu, Qinggong,Robertson, Alex ,W.,Ma, Tao,Fan, Qun,Han, Buxing,Jung, Yousung,Sun, Zhenyu Royal Society of Chemistry 2018 Chemical Science Vol.9 No.2

<▼1><P>The doping of Pd with a small amount of Te can selectively convert CO<SUB>2</SUB> to CO with a low overpotential.</P></▼1><▼2><P>Designing highly selective and energy-efficient electrocatalysts to minimize the competitive hydrogen evolution reaction in the electrochemical reduction of aqueous CO<SUB>2</SUB> remains a challenge. In this study, we report that doping Pd with a small amount of Te could selectively convert CO<SUB>2</SUB> to CO with a low overpotential. The PdTe/few-layer graphene (FLG) catalyst with a Pd/Te molar ratio of 1 : 0.05 displayed a maximum CO faradaic efficiency of about 90% at –0.8 V (<I>vs.</I> a reversible hydrogen electrode, RHE), CO partial current density of 4.4 mA cm<SUP>–2</SUP>, and CO formation turnover frequency of 0.14 s<SUP>–1</SUP> at –1.0 V (<I>vs.</I> a RHE), which were 3.7-, 4.3-, and 10-fold higher than those of a Pd/FLG catalyst, respectively. Density functional calculations showed that Te adatoms preferentially bind at the terrace sites of Pd, thereby suppressing undesired hydrogen evolution, whereas CO<SUB>2</SUB> adsorption and activation occurred on the high index sites of Pd to produce CO.</P></▼2>

Targeting SHCBP1 Inhibits Cell Proliferation in Human Hepatocellular Carcinoma Cells

Tao, Han-Chuan,Wang, Hai-Xiao,Dai, Min,Gu, Cheng-Yu,Wang, Qun,Han, Ze-Guang,Cai, Bing Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.10

Src homology 2 domain containing (SHC) is a proto-oncogene which mediates cell proliferation and carcinogenesis in human carcinomas. Here, the SHC SH2-domain binding protein 1 (SHCBP1) was first established to be up-regulated in human hepatocellular carcinoma (HCC) tissues by array-base comparative genome hybridization (aCGH). Meanwhile, we examine and verify it by quantitative real-time PCR and western blot. Our current data show that SHCBP1 was up-regulated in HCC tissues. Overexpression of SHCBP1 could significantly promote HCC cell proliferation, survival and colony formation in HCC cell lines. Furthermore, knockdown of SHCBP1 induced cell cycle delay and suppressed cell proliferation. Furthermore, SHCBP1 could regulate the expression of activate extracellular signal-regulated kinase 1/2 (ERK1/2) and cyclin D1. Together, our findings indicate that SHCBP1 may contribute to human hepatocellular carcinoma by promoting cell proliferation and may serve as a molecular target of cancer therapy.

Phenomenology of the Littlest Higgs Model

Tao Han 한국물리학회 2004 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.45 No.2

The little Higgs idea is a new way to solve the \little hierarchy" problem by protecting the Higgs mass from quadratically divergent one-loop corrections. I describe the phenomenology of one particular realization of the little Higgs idea: the \Littlest Higgs" model.

5G Converged Cell-Less Communications in Smart Cities

Han, Tao,Ge, Xiaohu,Wang, Lijun,Kwak, Kyung Sup,Han, Yujie,Liu, Xiong Institute of Electrical and Electronics Engineers 2017 IEEE communications magazine Vol.55 No.3

<P>Ubiquitous information service converged by different types of heterogeneous networks is one of fundamental functions for smart cities. Considering the deployment of 5G ultra-dense wireless networks, 5G converged cell-less communication networks are proposed to support mobile terminals in smart cities. To break obstacles of heterogeneous wireless networks, the 5G converged cell-less communication network is vertically converged in different tiers of heterogeneous wireless networks and horizontally converged in celled architectures of base stations/access points. Moreover, the software defined network controllers are configured to manage the traffic scheduling and resource allocation in 5G converged cell-less communication networks. Simulation results indicate the coverage probability and the energy saving at both base stations and mobile terminals are improved by the cooperative grouping scheme in 5G converged cell-less communication networks.</P>

淺議對韓漢語虛詞敎學

韓松濤(Han Song-Tao),張泰源(Jang Tae-Won) 동아인문학회 2010 동아인문학 Vol.17 No.-

본문은 외국인들에게 중국어를 가르치는 가운데 발생하는 어려움 가운데 하나라고 할 수 있는 허사 교육의 방법에 관하여 연구 분석한 것이다. 허사의 수량이 비교적 많고, 용법이 다양하며 허사의 의미 또한 복잡 미묘해서 외국인 학생들의 입장에서 보면 중국어 학습의 어려운 부분이라고 할 수 있다. 그래서 외국인에게 중국어의 허사를 가르치는 가운데에 올바른 방법을 찾는다면, 곧 교육적 효율과 교육의 수준을 높이게 된다. 한국학생들 입장에서 본다면 한국어와 중국어는 모두 한자권역에 속하여, 중국어를 처음 배우는 사람이라도 중국어에 대하여 처음 접하는 당혹감을 상대적으로 덜 하게 된다. 이는 한국 학생들이 중국어를 학습하는 유리한 조건이 된다. 초급단계에서 교수는 이 점에서부터 출발하여 중국어를 잘 학습하려는 믿음을 증강시킬 수 있다. 그러나 가르치는 중점은 한국어와 중국어의 차이점에 두고 가르쳐야 학생들로 하여금 이 두 언어의 차이점에 대하여 충분히 이해할 수 있도록 하여야 학생들이 최대한 모국어의 규율과 사용원칙의 집착에서부터 벗어날 수 있게 한다. 즉 한국어 지식으로부터 비롯된 오류의 영향에서 부터 자유롭게 할 수 있다. 그래서 우리는 허사 교학 중에서 대비법을 먼저 채택한 것이다. 대비법 가운데 중국어, 한국어 대비를 설명하는 것 이외에 중국어 허사 내부적 차이점에 대해서도 대비법을 적용하여 설명하였다. 즉, 허사가 있는지 없는지의 대비와 허사 출현의 서로 다른 위치에 대한 대비를 말한다. 허사 가운데의 비슷한 낱말에 대해서 우리는 종류귀납이라는 방법을 취한다. 이러한 방법의 사용의 중점은 허사종류를 귀납 정리하는데 있지 않고 종류귀납의 기초위에 한 개의 종류 중에 각 구성원 사이의 차이점을 찾아내는 것이다. 학생에게 서로 다른 것을 찾아내게 할 때 우선 정확하고, 전면적으로 사고하게 하여 먼저 허사와 연결하는 명사나 명사구의 성질을 구별하게 할 뿐 아니라 위어의 성질까지 고려하도록 하여야 한다. 더욱 더 명확하게 분류하고 이해하도록 하기 위해서 교수들에게 예문을 더욱 더 많이 사용하도록 하며, 아울러 도표의 형식을 사용하여 결론을 도출하는 것이 교학적 효율을 높이는 방법이라고 건의하고자 한다.

汉韩视觉感官词 “大” 和 “크다” 的词义投射

韩松涛(Han Song tao) 동양한문학회 2015 동양한문학연구 Vol.42 No.-

시각감각기관은 사람의 중요한 감각기관 중의 하나이며, 색채, 명암, 공간적 크기 등 다른 감각기관보다 더 풍부한 내용들을 받아들일 수 있다. 그리고 이렇게 받아들여진 내용들은 시각감각어를 통해 표현하게 된다. 중국어 ‘大’와 한국어 ‘크다’는 사람들의 넓은 공간의 인지를 나타내는 일종의 언어적 표현이다. 중국어 ‘大’와 한국어 ‘크다’는 시각감각어로, 사물의 면적이나 부피, 용량 등이 일반적 기준을 초과한다는 의미를 나타내며, 이는 사람들이 공간적 개념으로 사물을 인지한 것에 대한 결과이다. 중국어 ‘大’와 한국어 ‘크다’의 다의 구조에서 우리는 다음과 같은 사실을 발견할 수 있다. 각각이 공간적 개념의 근원 영역에서 출발하여 정도, 성질, 수량 등 다른 목표 영역으로 투사되는데 양자는 투사하는 방향은 비슷하지만 투사한 후 나타나는 의미는 완전히 대응되지 못한다는 것이다. 본고에서는 중국어 ‘大’와 한국어 ‘크다’가 의미를 투사하는 과정에서 나타나는 차이를 분석하고 각각의 인지적 특징에 대해 검토하도록 하겠다. Visual sense is one of the important senses of human beings, which offers us more abundant contents than any other senses. For instance, we can have access to colors, lights and space through visual sense and we can use visual sensory words to describe these contents. As a language presentation of human’s vast spatial perception, “大” in Chinese and “크다” in Korean is a good case in point. As a visual sensory word, “大” in Chinese and “크다” in Korean describes the size, volume or capacity of an object that exceeds normal standard. It is the result of human’s perception of an object in the concept of space. However, in the polysemy structure of “大” in Chinese and “크다” in Korean, we find both words describe the contents projecting from the source conceptual domain of the space to other target domains such as extent, property and quantity. We also realize that the projection direction of both words is almost the same, but the meanings after projection do not show one hundred percent equivalence. The paper aims to analyze the similarities and differences of both words in the course of projection and discuss their cognitive characteristics.

Effect of Molybdenum and Chromium on Hardenability of Low-Carbon Boron-Added Steels

( Fu Tao Han ),( Byoung Chul Hwang ),( Dong Woo Suh ),( Zuo Cheng Wang ),( Duk Lak Lee ),( Sung Joon Kim ) 대한금속재료학회 ( 구 대한금속학회 ) 2008 METALS AND MATERIALS International Vol.14 No.6

The hardenability of low-carbon boron-added steels containing molybdenum or chromium was studied using dilatometry, thermodynamic calculations, and secondary ion mass spectroscopy (SIMS). The combined addition of boron and molybdenum was found to be more effective than that of boron and chromium in enhancing the hardenability of boron-added steels. In particular, the addition of 0.5 wt.% molybdenum to the boron-added steel almost completely suppressed the formation of polygonal ferrite even at a slow cooling rate of 0.5℃/s. The synergistic effect of the combined addition of molybdenum and boron is thought to be due to both the suppression of M23(C,B)6 precipitation resulting from the deterioration of phase stability and the reduction of carbon diffusivity by the molybdenum addition.