OS Security Enhancement System by Considering Security Level

Tai-Hoon Kim,Gil-cheol Park,Seok-soo Kim 보안공학연구지원센터 2007 International Journal of Multimedia and Ubiquitous Vol.2 No.3

Trusted operating systems (OS) provide the basic security mechanisms and services that allow a computer system to protect, distinguish, and separate classified data. Trusted operating systems have been developed since the early 1980s and began to receive National Security Agency (NSA) evaluation in 1984. The researches about trusted OS are proceeding over the world, and new product type using the loadable security kernel module (LSKM) or dynamic link library (DLL) is being developed. Most important concept in this paper is Security Level proposed by Dr. Tai-hoon Kim, because this concept should be considered in every operational environment. This paper assumed security level 1st proposed by Dr. Taihoon Kim, and proposes a special type of product using LSKM and specific conditions for operational environment should be.

Definition of Security Practices in STP for SLMM

Tai-Hoon Kim 보안공학연구지원센터 2008 International Journal of Hybrid Information Techno Vol.1 No.1

To manage security level of information system (IS), organizations must select security practices (SP) first, and then apply them according to security level. SP can be divided into 2 groups security management part (SMP) and security technology part (STP), and some SPs in SMP were proposed already by Drs. Tai-hoon Kim and Kouichi Sakurai [1]. In this paper, we propose some SPs in STP to construct STP for Security Level Management Model (SLMM).

POS System Design in Security Level 1st

Seok-soo Kim,Tai-hoon Kim 보안공학연구지원센터 2007 International Journal of Multimedia and Ubiquitous Vol.2 No.2

POS system is a supply net administration system for customer management. It becomes an essential element in distribution industry to construct database, and uses XML-Encryption to complement PKI techniques and standards for security. POS system has four advantages. First, it does not have to be certificated and transmit data every time because there is no server. Second, it can integrate database by using XML and improve portability of program itself. Third, transmitted data is safe because of XML-Encryption. Fourth, processing speed will be faster because it gathers data from data transmission. All systems should be designed by considering security level to reduce non-necessary burdens. The concept of security level management was developed by Dr. Tai-hoon Kim a few months ago, and this paper used this idea. In this paper, Security Level 1st environment was considered to design POS systems.

수질환경 측정용 수원대 DO센서의 실험실적 성능 평가

金胎辰,李相勳 수원대학교 산업기술연구소 1995 산업기술연구소논문집 Vol.10 No.-

The Dissolved Oxygen(DO) electrode fabricated by the research team at the University of Suwon was experimentally compared with the YSI DO electrode which is the most widely-used DO electrode in Korea. The sensitivity of the two electrodes were measured under various DO conditions and different pH environment. The findings of the experiment are as follows. Firstly, in DO range between 1.5 and 7.7㎎/ℓ, the two electrodes showed a good agreement in sensitivity. Secondly, in pH range between 3.0 and 10.0, the two electrodes showed a good agreement in sensitivity. The maximum difference was within the range of experimental error. It was concluded that the locally fabricated electrode performed as good as YSI DO electrode in its sensitivities of DO and pH.

백혈병 세포를 이용한 종양-림프구 혼합면역반응의 임상적 의의

김희제,조현일,김태규,한훈,김춘추,민우성 대한조혈모세포이식학회 2000 대한조혈모세포이식학회지 Vol.5 No.1

본 연구는 골수성 백혈병세포와 공여자 유래의 말초 혈액 단핵구를 실험관 내에서 배양하여 백혈병 특이 세포 독성 T 세포를 HLA 일치 형제 공여자로부터 유도하고, 유도된 T 세포의 특성을 규명하여 조혈모세포이식 후의 임상적인 소견과의 연관성을 조사하고자 하였다. 만성기 5례, 가속기 3례, 급성기 2례를 포함하는 10례의 만성 골수성 백혈병 환자들과 1차 완전 관해 상태에 있는 2례의 급성 골수성 백혈병 환자들의 말초혈액에서 수상돌기 세포를 유도하여 항원제시세포로 사용하였다. 백혈병 세포에 대한 세포 독성 T 세포의 효과적인 유도는 급성 골수성 백혈병, 만성 골수성 백혈병의 만성기와 급성기, 가속기의 순서였다. 세포 독성은 세가지 표적 세포인 K562 세포주, 백혈병 세포와 환자의 PHA 자극세포에 대한 세포독성 실험을 통해 세포독성 T 세포에 의한 것인지 또는 자연 살해 세포 (NK 세포)에 의한 것인지 구별할 수 있었다. 세 가지 표적세포에 대한 세포살해는 결과를 종합하여 동종 조혈모 세포이식 후 백혈병의 제발 가능성을 예측할 수 있었다. 즉 세가지 표적세포들 중 한 가지에서라도 양성 반응을 보인 경우 이식편대 백혈병 효과로 인해 백혈병 재발률이 낮았다. 2례의 만성 골수성 백혈병 가속기 환자들에서 유도된 백혈병성 수상돌기 세포들은 세포의 형태학적 소견과 유세포 분석기를 사용한 면역 표현형이 수상돌기 세포와 동일하였으나 이를 이용해 유도한 세포독성 T 세포는 유의한 활성을 나타내지 않았다. 결론적으로 백혈병 세포에 대한 공여자 기원의 항 백혈병 세포독성 T 세포는 Interleukin-2로 자극하여 실험관내 배양이 가능하며, 이를 통해 질환의 특성이나 백혈병 세포의 생물학적 이질성에 따른 세포 살해능의 다양성을 규명할 수 있을 것으로 사료된다. Background:Allogeneic bone marrow transplantation (BMT) is an effective treatment for a large number of patients suffering from malignant hematological disorders. An immune-mediated graft-versus-leukemia (GVL) effect is an important feature of this treatment modality. Although numerous clinical and experimental data have given evidence for both T and NK cells involved in this phenomenon, leukemic relapse and graft-versus-host disease (GVHD) mediated by T cells still remain the major problems of allogeneic BMT. In this study, we tried to define the characteristics of anti-leukemic CTLs and to evaluate the clinical implications of the cellular immunity in leukemic patients. Methods:Leukemic cells were incubated concurrently with peripheral mononuclear cells isolated from HLA-matched sibling donors. Cytotoxic T lymphocytes (CTLs) have been generated from peripheral blood cells of 12 patients with chronic myelogenous leukemia (CML) including 5 in chronic phase (CP), 3 in accelerated phase (AP), 2 in blastic crisis (BC) and 2 patients with acute myelogenous leukemia (AML) in first complete remission. The activity of CTLs and NK cells was measured by 51Cr release assay using autologous leukemic cells, K562 cell line and patient's PHA blasts as target cells. Results:The efficacy of generating CTLs against leukemic target cells were AML, CML-CP and CML-BC, CML-AP in order. Low leukemia relapse events was found to be associated with the strong intensity of cytotoxcity for K562 cell lines, and in addition to this, if we combine the cytotoxicity effects for all thee target cells, the possibility of relapse after allogeneic stem cell transplantation (SCT) was significantly predictable. Any significant association of the cytotoxicity against three target cells with GVHD was not found. Sex-matching or mismatching between donor and recipient did not affected on the NK cell activity. Conclusion:Our results demonstrated that donor-derived antileukemic cytotoxic T-cells against patient's own leukemic cells are producible in vitro and the activity of CTLs and NK cells may be variable according to disease-specificity or to biological heterogeneity of leukemia. If the specific, stable and reproducible anti-leukemic CTLs could be generated in vitro, these CTL lines could be used for the treatment of relapsed or predictable relapse high-risk leukemia after allogeneic BMT and for post-mini-transplantation immunotherapy in the near future.

상아질 결합제의 생체적합성에 관한 연구

김성훈,진태호 원광대학교 치의학연구소 2003 圓光齒醫學 Vol.12 No.3

This study was investigated to evaluate the biocompatibility of dentin bonding agents. The 4th generation dentin bonding agents such as Scothbond Multi-Purpose(3M, USA), Clearfil Liner Bond 2(Kuraray, Japan), All Bond 2(Bisco, USA), and 5th generation dentin bonding agents such as Single bond(3M, USA) Prime & Bond NT(Dentsply, Germany), and One Step(Bisco, USA) were used in this study. The viability of normal human pulp cell, gingival fibroblast, immortalized gingival fibroblast and HaCaT cell was measured in vim for evaluation of cytotoxicity on dentin bonding agents, and the response of pulp tissue(organotypic tooth slice culture) was analyzed and evaluated with light microscope after application of dentin bonding agents at cutting incisor edge of rats. The results obtained from this study were as follows : I. The gingival fibroblast was the most sensitive to toxicity of dentin bonding and HaCaT cell was the least. 2. The cytotoxicity of One step was low and that of ScotchbondScotchbond Multi-purpose was high in pulp cell and immortalizedginggival fibroblast. 3. The cytotoxicity of the 5th generation dentin bonding agent was lower than that of 4th generation dentin bonding agent in gingival fibroblast 4. Scotchbond Multi-Purpose showed the highest cytotoxicity comparativelyn most cells including HaCaT cell. 5. At 2 days after cultivation of tooth slice organ, them was no significant change in alveolar bone and periodontal ligament according to dentin boading apts. Odntoblasts and pulp cell population was excellent in the 5th generation dentin bonding agents after 2 days cultivation, and the similar response of odntoblasts and pulp cell was revealedafter 10 days cultivation. Collectively, in vim, cell viability and tooth slice organ culture test revealed similar results. From this study, we find out the some tendency that Scotbond Milti-Purpose is relatively more cytotoxic and One-Step is less

침전성인자를 이용한 생물학적 고형물의 침전속도식과 고형물 플럭스 분석

김진우,최영균,이종훈,김희준,정태학 대한상하수도학회 2002 상하수도학회지 Vol.16 No.3

Equations on settling velocity of the activated sludge were developed by including sludge settleability parameters (SSP) and solids flux at a secondary settling tank was analyzed using the empirical equations, and an optimal solids loading rate was evaluated in this study. SVI, SSVI, DSVI and SSVI_3.5 were adopted as the SSP and a best fitting between observed and calculated zone settling velocity was obtained when SSVI_3.5 was used. Measured solids flux at the secondary settling tank was lower than that recommended by the national design criteria. Optimal solids loading rate and subsequent limiting solids flux can be derived if SSVI_3.5 is used instead of other SSP. Limiting solids flux calculated using SVI showed higher value than that calculated using SSVI_3.5 and the limiting solids flux could be better estimated when SSVI_3.5 was used because the calculated zone settling velocity using SSVI_3.5 was closer to the measured value.

다공질 규소의 라만 산란

김태균,김영유,서영석,조창호,나훈균 公州大學校 基礎科學硏究所 1998 自然科學硏究 Vol.7 No.-

양극반응 전류밀도를 변화시키면서 다공질 규소를 제작하여 라만산란을 관측하였다. 전류밀도가 증가함에 따라 라만신호는 520.5㎝-₁에서 멀어졌으며, 봉우리의 반치폭이 증가하였다. 또한 전류밀도 증가에 따라 원통형 다공질 결정의 직경은 감소함이 계산되었으며, 길이가 길어짐을 AFM으로 관찰하였다. The Raman scattering was studied from the porous silicons which were made by changing anodization current. As the current density was increased, it was observed that Raman was gradually far from the value of 520.5 cm￣¹and the full width half maximum increased. The decrease of radius of cylindrical porous crystal was calculated and the increase of its length was investigated through AFM.

HLA-DPB1 유전자 형별법 개발

김태규,이혜정,정서영,정태준,한훈 대한조혈모세포이식학회 1997 대한조혈모세포이식학회지 Vol.2 No.1

연구배경: HLA-DP 유전자는 DR 및 DQ와 같이 항원제공 세포(APCs), B 세포 및 활성화된 T 세포등의 표면에 발현되는 class Ⅱ 유전자로서 외인성 항원제공시 MHC 제한(restriction)과정을 통해 면역 반응에 관여한다. DP 항원 분자는 PLT(primed lymphocyte test)와 같은 세포학적 방법에 의해 처음으로 규명되었고, 이어서 혈청학적 형별이 시도되었으나, DR, DQ 분자에 비해 발현 정도가 낮아 형별에 어려움이 있었다. 최근 DP 유전자의 염기서열이 밝혀짐에 따라 DNA 수준에서 DP 형별이 가능하게 되었으며, 지금까지 DPA1 10개, DPBI 77개의 대립유전자가 밝혀졌다. 본 연구는 이식의 결과 및 질병 발생과 연관이 있다고 추정되는 HLA-DPB1 대립유전자를 DNA 수준에서 형별하고 정상 한국인의 DP 대립유전자 분포를 확인하기 위해 시도되었다. 방법: HLA-DPB1 유전자 중 초가변부위(hypervari-able region)가 있는 exon 2 부위를 일차적으로 증폭시킨후, 17종의 probe를 사용하여 PCR-SSOP를 실시하였고, PCR-SSP에는 5종의 primer를 사용하였다. 이들 방법은 DP형이 알려진 미국 UCLA 대학의 international cell exchange sample 88개를 표준 DNA 시료로 이용하여 확립하였다. 결과: 36종류의 HLA-DPBI 대립유전자를 형별할수 있음을 확인하였다. 그러나 DPBI*0402와 0601 대립유전자를 동시에 갖는 heterozygote인 경우에는 DPBI*0201와 2001을 동시에 갖는 heterozygous와 구분이 어려웠다. 100명의 정상 한국인에서 DPBI 대립 유전자형의 분포를 조사한 결과 한국인에서는 11종류의 HLA-DP 대립유전자가 존재함을 확인하였고, DPBI*0501(36.5%), 0201(27%), 0402(10.5%) 대립유전자의 순으로 분포되어 있었으며 검출율은 100%였다. 결론: 이상의결과로 골수 이식 등 이식시 공여자와 수혜자간의 조직적합성은 HLA-DP, DQ뿐만 아니라 DP도 확인 하게되었으며, 앞으로 질병과의 연관성 연구에서 이용될수 있을것으로 사료된다. Background: The HLA-DP genes are highly polymorphic, which encode heterodimeric cell surface glycoproteins that play a role in the immune response as restriction elements in antigen presentation. HLA-DP antigens were initially defined through the primed lymphocyte test (PLT), and the serological typing has been performed which is practically difficult because the expression of DP molecules is very low, comparing with that of DR and DQ. Recently, DNA sequencing and PCR have allowed the various and extensive study on the HLA-DP genes. We developed the molecular typing method for HLA-DPBI alleles, and studied the distribution in normal Korean population. Methods: After PCR amplification of hypervariable exon 2 regions in HLA-DPBI gene, both PCR-SSOP (sequence specific oligonucleotide probes) with 17 probes and PCR-SSP (sequence specific primers) by 5 Primers were used. And this method was tested using a international pannel DNA as standard. Results: Total 36 alleles of HLA-DPBI were defined in the standard DNA pannel. However, DPBI*0.402, and 0601 heterozygote could not be distinguished from DPBI*0201 and 2001 heterozygote. And 11 alleles were defined in 100 normal Koreans and the common alleles were DPBI*0501 (36.5%). 0201 (27%) and 0402 (10.5%). The detection rate was 100% in this study. Conclusion: As the results, the molecular typing of HLA-DPBI alleles is possible for the accurate matching between donor and recipient in born marrow transplantation and for the study of disease association.

Zigbee sensor 모듈에 적용 가능한 소형 PCB 안테나의 최적 설계 기법 연구

이영순,김의중,이태훈,정훈희 금오공과대학교 2006 論文集 Vol.27 No.-

본 논문에서는 소형 Zigbee sensor 모듈에 적용하기에 적합한 모듈 일체형 안테나의 최적 설계시법을 제기하고자 한다. Zigbee sensor 모듈에서 사용되는 2.45GHz 대역에 적합한 모듈 일체형 안테나를 meander slit 구조를 이용하여 최적설계 과정을 보이고, 최적화된 안테나의 설계 결과를 보였다. 그리고 기존 chip 안테나의 성능 비교를 위해 최대 동작거리 및 방사출력을 비교한 결과를 제시 하였다.