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Sung, Kyoung,Kim, Ji Yong,Lee, Yeoun Joo,Hwang, Eun Ha,Park, Jae Hong The Korean Society of Pediatric Gastroenterology 2014 Pediatric gastroenterology, hepatology & nutrition Vol.17 No.3
Purpose: The etiology of acute gastroenteritis (AGE) has changed since the introduction of the rotavirus vaccination. The aim of this study was to clarify which common pathogens, both bacterial and viral, are currently causing AGE in infants. Methods: Infants with acute diarrhea were enrolled. We tested for 10 bacterial pathogens and five viral pathogens in stool specimens collected from infants with AGE. The clinical symptoms such as vomiting, mucoid or bloody diarrhea, dehydration, irritability, and poor oral intake were recorded, and laboratory data such as white blood cell count and C-reactive protein were collected. The clinical and laboratory data for the cases with bacterial pathogens and the cases with viral pathogens were compared. Results: Of 41 total infants, 21 (51.2%) were positive for at least one pathogen. Seventeen cases (41.5%) were positive for bacterial pathogens and seven cases (17.1%) were positive for viral pathogens. Staphylococcus aureus (13 cases, 31.7%) and Clostridium perfringens (four cases, 9.8%) were common bacterial pathogens. Norovirus (five cases, 12.2%) was the most common viral pathogen. Fever and respiratory symptoms were common in the isolated viral infection group (p=0.023 and 0.044, respectively), whereas other clinical and laboratory data were indistinguishable between the groups. Conclusion: In our study, S. aureus (41.5%) and norovirus (12.2%) were the most common bacterial and viral pathogens, respectively, among infants with AGE.
Synthesis of Oxazolidinone Phosphonate Derivatives, Part II
Hwang, Jae-Min,Yeom, Sung-Ho,Jung, Kang-Yeoun Korean Chemical Society 2007 Bulletin of the Korean Chemical Society Vol.28 No.5
Several oxazolidinones, a new class of synthetic antibacterial agents, have shown biological activity against multidrug-resistant gram positive organisms such as staphylococci, streptococci, and enterococci. Previous results of our studies with benzoxazolidinone phosphonate derivatives have demonstrated very low antibacterial activity. In the course of our studies directed towards the discovery of noble antibacterial agents, we have synthesized several new derivatives of oxazolidinone phosphonates prepared efficiently from commercially available amino acids. These compounds are tested for in vitro antibacterial activity and one of the compounds showed promising results allowing us to pursue further studies.
단련한 흰쥐의 속근 및 지근에 Glycogen 과저장이 운동 지구력에 미치는 영향
연동수(Yeoun, Dong-Soo),황수관(Hwang, Soo-Kwan),김인숙(Kim, In-Sook),고성경(Ko, Seong-Kyeong),남택상(Nam, Taick-Sang),강두희(Kang, Doo-Hee) 대한생리학회 1988 대한생리학회지 Vol.22 No.1
This study was carried out to investigate relationships between maximal running time (MRT) and glycogen supercompensation in fast twitch white fibers (white vastus, WV), fast twitch red fibers (red vastus, RV) and slow twitch red fibers (soleus muscle, SM) of endurance-trained rats. Male rats of a Sprague-Dawley strain were divided into the trained groups and untrained groups. Untrained groups were acquired to run on the treadmill 10 minutes for 3 days and remained rest and maintained with mixed diet for 4 weeks. For last 10 days of resting period, the untrained rats were divided into 3 groups i.e. mixed diet (untrained control), high and low carbohydrate (CHO) diet groups. And each group was subdivided into 2 groups, one group was tested for the MRT and the other was sacrificed to measure the blood glucose, blood lactate, glycogen contents of liver and muscles. The experimental groups were trained on treadmill by a modified method of Constable et al. (1984) maintained with mixed diet for 4 weeks. After measurement of MRT of this group, they were also divided into high and low CHO groups and fed with these diet for 2 days and MRT of each group was measured again to see the effect of high or low CHO feeding on the MRT. Each group was maintained with the same diet for next 2 days during which some of the rats were sacrificed at given time intervals for the measurements of blood glucose and lactate, liver and the muscles glycogen. The results were summarized as follows; 1) In the untrained group, there were no significant differences between subgroups in MRT, glycogen conent of SM, RV and WV. But blood glucose concentration and glycogen content of liver of low CHO group were significantly lower than those of mixed diet group. 2) The MRT and glycogen content of SM, RV and WV of trained mixed diet group were significantly increased compared to those of untrained mixed diet group, but there was no significant difference in glycogen content of liver. 3) MRT of trained mixed, high CHO and low CHO groups were 137±9.8, 176±9.8 and 129±7.3 min respectively with the significant difference between them. 4) There were no differences in blood lactate concentrations between the trained high and low CHO groups immediately after maximal running and during recovery period. 5) Glycogen contents in RV and SM of trained high CHO group were significantly increased, and glycogen contents in RV, WV and liver of trained low CHO group were significantly decreased compared to those of trained mixed diet group. 6) Immediately after maximal running, the blood glucose concentrations of trained high CHO and low CHO groups were 73±4.0 and 67±6.9mg% respecitively. The blood glucose of the trained high CHO group was fully recovered within one hour by feeding. But blood glucose concentration of low CHO group was slowly recovered up to 114±4.1mg% after two hours of feeding and maintained. Those values were still significantly lower than that of trained mixed diet group. The synthetic rates of glycogen in liver and muscles during the recovery period followed the similar time course of the blood glucose recoveries in each group. These results suggest that an increase in MRT of trained high CHO group was attributed to the glycogen supercompensation in slow twitch muscle fibers. And a decrease in MRT of trained low CHO may be due to decreased glycogen contents of liver and muscles. The results also suggest that glycogen supercompensation was more evident in slow twitch red fibers of endurance-trained rats and blood glucose is one of the limiting factors of glycogen synthesis.
A Case of Post-Traumatic Pseudocyst in the Spleen Successfully Treated with Alcohol Sclerotherapy
Mun, Sang Wook,Lim, Taek-Jin,Hwang, Eun Ha,Lee, Yeoun Joo,Jeon, Ung Bae,Park, Jae Hong The Korean Society of Pediatric Gastroenterology 2015 Pediatric gastroenterology, hepatology & nutrition Vol.18 No.4
This report details a case of post-traumatic pseudocyst in the spleen that was successfully treated with sclerotherapy using ethanol. A sixteen-year-old boy visited our hospital for a follow-up examination of a splenic cyst. He had experienced blunt trauma to the abdomen three years prior to presentation. An abdominal computed tomography scan revealed a large cyst of the lower pole of the spleen. The cyst was $6.8{\times}9.5{\times}7.0cm$ and conservative management was tried. A follow-up ultrasonographic examination three years later revealed that the size of the cyst was unchanged and another treatment was needed to prevent complications. One session of sclerosis with ethanol (90 mL of 99% ethanol) percutaneously was applied to the cyst. A follow-up after four months revealed that the cyst had completely resolved.
박성근(Sung-Keun Park),황근연(Geun-Yeoun Hwang),권영수(Young-Soo Kwon) 한국조류학회II 2010 한국조류학회지 Vol.17 No.3
본 연구는 2005년 2월부터 2006년 10월까지 광릉숲 일대의 관람객이 조류분포에 미치는 영향을 분석하기 위하여 수행되었다. 10년간 광릉숲 일대를 방문한 관람객들은 한해 평균 402,484±284,023명이었다. 이들에 의한 소음도는 오전에 개방지역에서 평균 61.3±4.3dB, 비개방지역에서 평균 49.3±4.5dB이었으며, 오후에는 개방지역에서 평균 80.6±5.1dB, 비개방지역에서 평균 53.6±1.0dB로 나타나 오전과 오후 모두 개방지역에서 높았다(t=7.50, P<0.001, t=20.21, P<0.001). 관찰된 조류는 총 76종이었으며 비개방지역과 개방지역에서 각각 17종(16.8%) 및 8종 (7.9%)이 확인되었다. 단위면적당 관찰된 종수는 비개방지역(평균 19.51±1.0종/ha)이 개방지역(평균 15.69±0.8종/ha)보다 더 많았다(t=2.95, P<0.01). 밀도(개체수) 역시 비개방지역(평균 126.39±11.2개체/ha)이 개방지역(평균 83.67±6.1개체/ha) 보다 더 많았다(t=3.33, P<0.01). 인공소상에서의 번식률은 비개방지역(14.0%)이 개방지역(2.0%)보다 높았다(χ²=4.180, df=1, p<0.05). This study conducted from February 2005 to October 2006 to investigate effects of disturbances by visitors on bird distribution in Gwangneung Forest. During 10 years, the average number of visitors in Gwangneung forest were 402,484±284,023/year. The noise levels of opened area were higher than restricted area in all the time (t=7.50, P<0.001, t=20.21, P<0.001). In the morning, the average noise level of opened area was 61.3±4.3dB and the restricted area was 49.3±4.5dB. In the afternoon, the average noise level of open area was 80.6±re1dB and the restricted area was 53.6±1.0dB. The number of birds observed in common area of restricted area and open area was total 76 species. 17 species and 8 species were observed in only restricted and opened area, respectively. The average number of birds observed in restricted area (19.51±1.0/ha) was higher than open area (15.69±0.8/ha) (t=2.95, P<0.01). The average number of birds observed in restricted area (126.39±11.2/ha) were higher than open area (83.67±6.1/ha) (t=3.33, P<0.01). In the breeding success, nest boxes in restricted area (14.0%) was higher than open area (2.0%) (χ²=4.180, df=1, p<0.05).