T 및 B cell 測定 : 1. 1次 成績 Ⅰ. Results, Primary

金在植,崔成萬,金在龍,全東錫,朴正姬,徐相喆,金仁子,金在崇,金重明 慶北大學校 醫科大學 1982 慶北醫大誌 Vol.23 No.2

E-rosette法에 의한 T cell의 百分率과 螢光抗體法, 感作牛赤血球擔體法, 酵素抗體法 및 마우스赤血球 rosette法에 의한 B cell 의 百分率을 檢査하여 다음과 같이 요약할 수 있었다. 정상성인군의 active T cell은 26±8.2%이었고 total T cell은 72±4.9%이었다. B cell 는 螢光抗體法으로 22±5.4%, 感作牛赤血球擔體法으로 15.8±4.9%, 酵素抗體法으로 15±5.2% 그리고 mouse RBC-rosette法으로 17.2±4.1%이었다. 惡性腫瘍에 있어서 active T cell은 27.±10.4%이었고 total T cell 은 59±11.2%로서 정상인군에 비하여 유의한 감소를 보였다. 良性疾患에 있어서 T cell 은 정상인군에 비하여 유의한 차이를 볼 수 없었다. T cell percent by E-rosette and B cell by fluorescent antibody, senitized ox RBC rosette, enzyme antibody and mouse RBC rosette tests were performed. In healthy adult group the active T cell was 26±8.2% and total T cell was 72±4.9%, B cell by fluorescent antibody was 22.±5.40%, by ox RBC rosette 15.8±4.9%, by enzyme antibody 15±5.2% and by RBC-rosette 17.2±4.1%. In malignant tumor the active T cell was 27±10.4% and total T cell was 59±11.2%. In benign diseases T cell count showed no significant difference from normal adult group.

임상 가검물에서 분리된 균(대장균과 황색 포도균)의 약제 내성

김중명,김재식,김경선,김재룡,전동석,최성만,서상철,김인자,김재숭,이건일,김경숙 慶北大學校 醫科大學 1982 慶北醫大誌 Vol.23 No.2

1981년 1월에서 12월말까지 임상 제료에서 분리한 Escherichia coli (E. coli)와 Staphylococcus aureus (S. aureus) 중에서 무작위로 각 50주 씩 선택하여 원판 확산법과 평판 희섭법으로 그 내성주를 조사하여 다음과 같은 성적을 얻었다. 전체적으로 볼 때에 Teteracyclin (TET), Chloramphenicol (CM) 및 Ampicillin (AMP)에 대한 내성주가 가장 많았고, Amikacin (AMK)에 대한 내성주는 가장 적어다. 이것을 균종별로 보면 E. coli에 있어서는 TET, AMP 및 CM는 원판 확산법으로서 74∼76%, 평판 희석법으로서는 78∼94%가 내성주임을 나타내었고, 또 Cephalothin(CEP)은 원판 확산법에서는 8%가 내성주로 나타났으나, 평판 의석법에서는 52%가 내성주로 나타났다. S. aureus에 있어서는 TET는 원판 확산법으로 82%, 평판 희석법으로서는 78%가 내성주로 나왔고 Penicillin (P)은 원판 확산법에서는 56% 평판 희석법으로는 22%의 내성주가 나왔으며, GM과 CM은 원판확산법에서는 18∼44%, 평판 희석법에서는 56∼58%가 내성주로 나왔다. Each 50 strains of Escherichia coli and Staphylococcus aureus were selected at random out of the stock cultures which were isolated from the clinical materials in the bacteriological laboratory of the department of clinical pathology. Kyungpook National University Hospital from the first of January to the end of December in 1982, and their resistance against eight antibiotics were as follows; Escherichia coli and Staphylococcus aureus had the most resistant pattern against tetracyclin, chloramphenicol, and ampicillin, while they had the most sensitive pattern against amikacin in general. Escherichia coli revealed resistant pattern to tetracyclin, ampicillin, and chloramphenicol 74-76% by the disk diffusion method and 78-94% by the plate dilution method, and revealed resistant pattern to cephalothin 8% by the disk diffusion and 52% by the plate dilution. Staphylococcs aureus disclosed resistant pattern to tetracyclin 82% by the disk diffusion and 78% by the plate dilution, and disclosed resistant pattern to penicillin 56% by the disk diffusion and 22% by the plate dilution, and to gentamicin and-chloramphenicol 18-44% by the disk diffusion and 56-58% by the plate dilution.

직장 Dieulafoy 병변으로 다량의 혈변을 보인 1 예

김태영;이상헌;김지현;배영환;정은주;김승만;지삼룡;설상영 인제대학교 2011 仁濟醫學 Vol.32 No.-

Dieulafoy’s lesion is very rare cause of gastrointestinal bleeding, Deiulafoy’s lesion is exposure of non ulcerative, abnormally large tortuous, thick- walled artery in the muscularis mucosa through a small submucosal defect. It is usullay found on stomach antrum and lesser curvature side of the proximal body, and possibly found on any sites throughout whole gastrointestinal tract, but rarely on rectum. The principal of treating Dieulafoy’s lesion was the surgical resection of lesion, but recently remarkable advances in endoscopic technique make endoscopic approach more popular. We report a case of rectal Dieulafoy’s lesion successfully treated with endoscopic hemoclipping in an elderly female patient.

HMDSO와 산소를 사용한 플라즈마 중합박막의 FTIR 연구

김성용 忠州大學校 2003 한국교통대학교 논문집 Vol.38 No.2

SiOx films deposited by means of PECVD (plasma enhanced chemical vapor deposition) using HMDSO (hexamethyldisiloxane) and oxygen were studied using FTIR-ATR technique. The substrate effects of the polymerized films were investigated using PET (polyethylene terephthalate) and PC (polycarbonate) films. The FTIR results at different penetration depths showed that the chemical bond structure was different at the substrate/film interface than that of the polymerized film. The same chemical bond structure was observed for the film deposition direction above the interface. The different substrate results in different Si-O-Si bond absorption peaks. The deposition rate of HMDSO/O2 was greater than 100 nm/min, which was relatively high rate. This study implies that the FTIR-ATR is effective in obtaining the film information

Norepinephrine이 흰쥐 해마박편에서 아미노산 신경전달물질 유리에 미치는 영향에 관한 연구

김성룡,김관식,정동균 대한구강생물학회 1990 International Journal of Oral Biology Vol.14 No.1

Present study was performed to clarify the effect of norepinephrine on the release of amino acid neurotransmitters employing hippocampal slices. Hippocampal slices (300-400㎛ thick) were prepared by the method of Spencer et al.(1976) and pre-equilibrated in Krebs-bicarbonate medium (KBM, pH 7.4) for 1 hr at 37℃. Pre-equilibrated slices were incubated in fresh KBM and then veratrine (25μM)-containing KBM for 10 min period. Basal and veratrine-induced release of GABA and glutamic acid were determined from recovered medium by HPLC. After 30 min resting period, slices were reincubated in norepinephrine-containing KBM and test agent plus veratrine-containing medium consecutively for 10 min period each to investigate the effect of norepinephrine on basal or veratrine-induced amino acid release from hippocampal slices. The observed results were as follows: 1. The release of GABA induced by the first and second 10min-exposure of 25μM veratrine was 246.9±16.82 nmol and 209.9±20.84 nmol, respectively. When compared with released amounts of GABA during the corresponding spontaneous periods, these were 7.3 and 7.3-fold increase respectively. 2. The release of glutamic acid induced by the first and second 10min-exposure of 25μM veratrine was 426.3±63.16 nmol and 377±61.83 nmol, respectively. When compared with released amounts of glutamic acid during the corresponding spontaneous periods, these were 9.9 and 10.2-fold increase respectively. 3. Norepinephrine (1-100μM) increased veratrine-stimulated and spontaneous release of GABA in dose-dependent manner. 4. Norepinephrine (1-100μM) inhibited veratrine-stimulated glutamic acid release in dose-dependent fashion.

후방 도달 반척추 절제술을 이용한 선천성 측만증의 치료

김진혁,이상민,정의룡 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.5

Objectives: To evaluate the surgical outcomes of congenital scoliosis with hemivertebra corrected by posterior vertebral column resection after a minimum follow up of 2years. Materials & Methods: Thirty five congenital scoliosis cases(20 males and 15 females) subjected to posterior vertebral column resection and without any previous operative intervention were analyzed. They were analyzed for deformity correction and complications. The mean age at operation was 14.6 year-old(range 2.6~35) and mean follow-up was 3.1 years(range 2.0~4.5). The preoperative index curve was 44.5±15.8° in coronal plane, and 22.7±35.9° in sagittal plane. Results: The total number of resected vertebrae were 36 : 17 in thoracic and 19 in lumbar. The deformity correction was 57.0% with 19.0±10.6° in the coronal plane and 69.0% with 7.0±14.9° in the sagittal plane. Mean operation time was 222.7±54.9 minutes with a total perioerative transfusion of 1992.0 ㎖. Complications were encountered in 3 patients(8.6%) : 1 hematoma and cauda equina syndrome, 1 fixation failures and 1 transient posterior cord syndrome. Conclusion: Posterior vertebral column resection in congenital scoliosis with hemivertebra is an effective method compared to anterior-posterior two stage hemivertebra resection. It could offer satisfactory correction of deformity and restoration of spinal balance.

高麗人參과 西洋參의 身部와 蘆頭部가 寒冷과 溫熱刺戟을 받은 흰쥐의 體溫, 脈搏數, 血液學的 變化에 미치는 影響

김동희,김성훈,이상룡 대한동의병리학회 1995 동의생리병리학회지 Vol.9 No.2

연구배경 : 最近 高麗紅蔘은 西洋蔘에 비해 發熱症을 誘發시키므로 中國人들에는 西洋蔘이 더 效果的이라는 광고가 만연하고 있지만, 우리나라 韓醫師들이 여름에 더위먹은 중에 高麗人蔘이 加味된 淸暑益氣湯과 生脈散을 渴症을 없애고 津液을 하는데 供給 應用하여 效果를 보고 있다는 점과 상충되며, 韓方에서는 人蔘의 身部만을 使用하고 蘆頭部는 頭痛을 誘發한다고 하여 除去하고있는데, <中草藥學>에서 "人蔘蘆頭도 찌거나 糖汁에 泡浸하여 痰飮, 久泄瀉, 陽氣下陷 등에 使用할 수 있다"고 하였으며, 紅蔘에는 蘆頭까지 使用하고 있다는 점에서 身部와 蘆頭部의 效能을 比較 檢討하여 향후 蘆頭部 使用의 實驗的 根據로 活用하기 위하여 本 硏究를 施行하였다. 방법 : 寒冷刺戟과 溫熱刺戟이 溫證과 冷證을 誘發하는 實驗方法으로 活用하여 5日間 高麗紅蔘, 西洋蔘, 高麗紅蔘蘆頭 및 西洋蔘蘆頭 등을 흰쥐에게 經口投與하고 溫熱刺戟과 寒冷刺戟을 준 後 直腸體溫, 脈搏數, 血液學的 變化를 測定하였다. 결과 : 本 實驗 結果 高麗紅蔘은 西洋蔘보다 體溫의 恒常性 維持에서 더욱 效果的이었고 高麗紅蔘과 西洋蔘의 蘆頭部는 身部보다 脈搏數를 增加시켰으며, 血液學的 變化에서도 效果가 있었으나 高麗紅蔘과 西洋蔘의 身部와 蘆頭部間에 큰 差異를 認定할 수는 없었다. Effects of head of korean red ginseng(HKG), head of western ginseng(HWG), body of korean red ginseng(BKG), body of western ginseng(BWG) on body temperature, pulse rate, hematological changes in rats treated with heat and cold stimuli were investigated. KG was more effective in keeping homeostasis of body temperatrue than WG to heat stimuli HKG and HWG regulated body temperatrue than WG to heat stimuli HKG and HWG regulated body temperature best up to mormal body temperature to cold stimuli. Every ginsengs tended to increase body temperture up to l hour after administration of ginsengs, but head part increased pulse rate more than body part of ginsengs. However, it was thought that there was'nt specific changes in hematological study between head and body parts of korean ginseng and western ginseng.

유체-구조물-지반 상호작용을 고려한 항만구조물의 지진응답 해석

김두기,류희룡,장성규,서형렬 국립7개대학공동논문집간행위원회 2004 공업기술연구 Vol.4 No.-

This paper presents the result of a study on the fluid-structure-soil interaction(FSSI) of a port structure under earthquakes. In this analysis, the fluid is modeled by the 4-node element which is a modification of a structural plane elements, and the port structure and foundation is modelled by the plane strain elements. Since the present method directly models the fluid-structure-soil interaction system by finite elements, if can be easily applied to the dynamic analysis of a 2-D port structure with complex geometry. Finally, results of seismic analyses are presented and compared to those of the seismic coefficient and the added mass methods.

퇴행성 요추 병변에서 척추경 나사를 이용한 요천추유합의 결과

김진혁,이상민,정의룡 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.5

Objective: To evaluate the efficacy of lumbosacral fusion with bilateral bicortical S1 pedicle screw fixation without anterior support on the basis of the fusion levels in degenerative lumbosacral disease. Materials and Methods: Seventy three patients were treated with posterior decompression and posterolateral fusion with bilateral bicortical S1 pedicle screw fixation. Their results were analyzed retrospectively with minimum 2-year follow-up. Postoperative anteroposterior and lateral radiographs were analyzed for S1 screw loosening, fixation failure and lumbosacral fusion. Medical records were analyzed for postoperative low back pain and complications. Results: S1 screw loosening was 1(6.3%) in 2 level fixations, 3(14.3%) in 3 levels, 7(5O.0%) in 4 levels and 13(86.7%) in more than 5 levels. Fixation failure was 1(4.8%) in 3 levels fixation, 1(7.1%) in 4 levels, 5(33.3%) in more than 5 levels. Non-union was suspected in 30 patients(41.1%), 1(14.3%) in mono-level fixation, 2(12.5%) in 2 levels, 8(38%) in 3 levels, 9(64%) in 4 levels and 10(67%) in more than 5 levels. Postoperative sustained low back pain was 1 in 3 levels fixation, 2 in 4 levels and 7 in more than 5 levels. Postoperative complications were detected in more than 3 level fixations ; hematoma in 2, wound infection in 6, progressive kyphosis in 2. Conclusion: Lumbosacral fixation with bilateral bicortical S1 pedicle screw could not provide satisfactory outcome in long level fusion especially in more than 4 levels fusion of degenerative lumbar disease.

척추경 나사 고정 및 후방 유합술만으로 치료한 Andersson 병변 : Andersson 병변 Andersson lesion

김진혁,이상민,정의룡 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.5

A60-year-old female patient with Andersson lesion is presented. Andersson lesion or spondylodiscitis in ankylosing spondylitis is a rare but well-known condition defined as an erosive and sclerotic process involving the intervertebral disc and adjacent vertebral bodies. The causes of this condition are not well understood. The Andersson lesion is often painful, and needs surgical treatment. The patient underwent segmental pedicle screw fixation and posterior fusion without any anterior procedure. The clinical features are presented with leterature review.