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      • Projections of summertime ozone concentration over East Asia under multiple IPCC SRES emission scenarios

        Lee, Jae-Bum,Cha, Jun-Seok,Hong, Sung-Chul,Choi, Jin-Young,Myoung, Ji-Su,Park, Rokjin J.,Woo, Jung-Hun,Ho, Changhoi,Han, Jin-Seok,Song, Chang-Keun Elsevier 2015 Atmospheric environment Vol.106 No.-

        <P><B>Abstract</B></P> <P>We have developed the Integrated Climate and Air Quality Modeling System (ICAMS) through the one-way nesting of global–regional models to examine the changes in the surface ozone concentrations over East Asia under future climate scenarios. Model simulations have been conducted for the present period of 1996–2005 to evaluate the performance of ICAMS. The simulated surface ozone concentrations reproduced the observed monthly mean concentrations at sites in East Asia with high R<SUP>2</SUP> values (0.4–0.9), indicating a successful simulation to capture both spatial and temporal variability. We then performed several model simulations with the six IPCC SRES scenarios (A2, A1B, A1FI, A1T, B1, and B2) for the next three periods, 2016–2025 (the 2020s), 2046–2055 (the 2050s), and 2091–2100 (the 2090s). The model results show that the projected changes of the annual daily mean maximum eight-hour (DM8H) surface ozone concentrations in summertime for East Asia are in the range of 2–8 ppb, −3 to 8 ppb, and −7 to 9 ppb for the 2020s, the 2050s, and the 2090s, respectively, and are primarily determined based on the emission changes of NO<SUB>x</SUB> and NMVOC. The maximum increases in the annual DM8H surface ozone and high-ozone events occur in the 2020s for all scenarios except for A2, implying that the air quality over East Asia is likely to get worse in the near future period (the 2020s) than in the far future periods (the 2050s and the 2090s). The changes in the future environment based on IPCC SRES scenarios would also influence the change in the occurrences of high-concentrations events more greatly than that of the annual DM8H surface ozone concentrations. Sensitivity simulations show that the emissions increase is the key factor in determining future regional surface ozone concentrations in the case of a developing country, China, whereas a developed country, Japan would be influenced more greatly by effects of the regional climate change than the increase in emissions.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Change in ozone level is determined by the combination of NO<SUB>x</SUB> and NMVOC emissions. </LI> <LI> Ozone level over East Asia would get worse in the near future (the 2020s) than far future. </LI> <LI> A high-concentration event generally increases and more frequently occurs in the future. </LI> <LI> Change in ozone air quality in a developing country depends more on emissions change. </LI> <LI> Change in ozone air quality in a developed country depends more on climate change. </LI> </UL> </P>

      • Effect of Changing Amniotic Fluid Osmolarity on the Li<sup>+</sup> Transport Through the Membrane Surrounding Amniotic Fluid in the Rabbit

        Chang. Jin-Keun,Lee. Sang-Jin,Sung. Ho-Kyung 대한생리학회 1993 대한생리학회지 Vol.27 No.1

        To study the regulation of amniotic fluid volume and electrolyte concentration by the Membranes surrounding the amniotic fluid, the rate of Li<sup>+</sup> disappearance from amniotic sac of expired fetuses were examined while increasing the amniotic volume and osmolarity in rabbits. After intraamniotic injection of 1 ml isosmotic saline (about 20% of the amniotic fluid volume) containing 15 mM LiCl and 0.5 g/L Censored, the time courses of Li<sup>+</sup> and Censored disappearance were determined. From there the Li<sup>+</sup> clearance through the extrafetal routes was estimated and compared with that obtained from living fetuses. The volume, Na<sup>+</sup> concentration and osmolarity of amniotic fluid were measured and their relationships with Li<sup>+</sup> disappearance were evaluated. The fellowing results were obtained: 1. The rate of disappearance from amniotic fluid of living fetuses during the first 30 minutes was strikingly higher for Li<sup>+</sup> than for Censored, suggesting that extrafetal routes exist. At 60 and 90 minutes, however, the disappearance rate of Li<sup>+</sup> was less than that of Censored, suggesting the possibility of Li<sup>+</sup> reentry through fetal urination. 2. The disappearance of Li<sup>+</sup> from the amniotic fluid of the expired fetus was substantial, although lower than that of living fetuses, throughout the experimental period. 3. The Na<sup>+</sup> concentration and the osmolarity of the amniotic fluid of expired fetus measured 30 minutes after an intraamniotic injection of isoosmotic saline showed wide variation, but thereafter they changed gradually towards the normal extracellular fluid level. 4. When the amniotic fluid was iso- or hyposmolar, the rate of Li<sup>+</sup> disappearance from the amniotic fluid of the expired fetuses showed little variation. However, when the amniotic fluid was hyperosmolar, the rate at 30 minutes was markedly lower than those of isosmotic or hyposmotic amniotic fluid. At 90 minutes, the rate of Li<sup>+</sup> disappearance in hyperosmolar fluid reached a similar level to the rate in isosmolar fluid. 5. The intraamniotic injection of 400 mOsm/L saline solution decreased the disappearance rate of Li<sup>+</sup> from expired fetuses, while the injection of mannitol into the maternal vein induced no significant change. From these results it is concluded that: 1) a significant amount of Li<sup>+</sup> may leave the amniotic fluid via filtration through the membranes surrounding the amniotic fluid, 2) during hyperosmolar challenge to amniotic fluid, osmotic bulk flow might counteract the filterable loss, and 3) Li<sup>+</sup> disappearance might continue even after the volume and osmolarity of the amniotic fluid have recovered to control values.

      • SCOPUSKCI등재
      • KCI등재

        Diagnostic Significance of Brainstem Auditory Evoked Potentials in Microvascular Decompression of Patients with Hemifacial Spasm or Trigeminal Neuralgia

        ( Sang-koo Park ),( Sung-hyuk Lim ),( Chan-woo Park ),( Jin-woo Park ),( Sung-ho Chang ),( Keun-hye Park ),( Hae-ja Park ),( Ji-hye Song ),( Dong-ok Uhm ),( Ki-bong Kim ) 대한임상검사과학회 2011 대한임상검사과학회지(KJCLS) Vol.43 No.1

        The purpose of this study was to analyse brainstem auditory evoked potentials (BAEP) wave change data during microvascular decompression (MVD). The nerve function of Cranial Nerve VIII is at risk during MVD. Intraoperative monitoring of BAEP can be a useful tool to decrease the danger of hearing loss. Between January and December 2009, 242 patients had MVD for hemifacial spasm (HFS) and trigeminal neuralgia (TN). Among intraoperative BAEP changes, amplitude of V-V’ was the most frequently observed during cerebellar retraction and decompression step of the MVD procedure. 138 patients (57%) had no BAEP change while 104 patients (42.98%) had BAEP change. 69 patients (28.5%) had Type A-I, 16 patients (6.6%) had Type A-II, 5 patients (2.1%) had Type B, and 13 patients (5.37%) had Type C. MVD is a surgical procedure to relieve the symptoms (e.g. pain, muscle twitching) caused by compression of a nerve by an artery or vein. During BAEP intraoperative monitoring, the surgical step is important in interpreting the changes of wave V. Several potential mechanisms of injury may affect the cochlear nerve, and complete loss of BAEP is often associated with postoperative hearing loss. Intraoperative BAEP monitoring may provide an early warning of hearing disturbance after MVD.

      • KCI등재

        A proposal of the Optimal Angle of Standing Assistant Chair for the Elderly by Comparing of Pressure Distribution on Hip

        Sung-Ho Chang(장성호),Ji-Hoon Baek(백지훈),Jung-Eon Lee(이중언),Nematov Mirazamjon(Nematov Mirazamjon),Seok-Wan-Kang(강석완),Wang-Bum Lee(이왕범) 한국산업경영시스템학회 2018 한국산업경영시스템학회지 Vol.41 No.3

        One of the most performed action in daily life is standing up from sitting position. As the population of the world is aging at the high rates, people may face problems with reduced muscle strength as well as psychological changes. This can lead elderly people having difficulties with standing up from chair. Now, with the aging trend worldwide, products are being developed that can support the lives of the elderly. This study examines the distribution of hip pressure in relation to the seating positions of the standing assistance seats under development to prevent standing up accidents in older adults. The currently developing standing assistant chair designed to tilt to a maximum angle of 25 degrees. At over 25°, design considers that older people are at risk of thrown back out of that force and that the forces exerted on their arms and legs can be a significant burden to older people. By considering danger of higher than 25° for older people which is experimented in the basis of static capturing approach in previous papers, it is experimented people with age group of 20~60 on 0° to 25° tilting angle on the basis of dynamic capturing method in order to pick convenient angle of inclination. Moreover, tried to find the optimum angle by comparing the hip pressure distribution when seated at the edge of the seat and at the center of the seat with the pressure distribution sensor.

      • Effect of Changing Amniotic Fluid Osmolarity on the $Li^+$ Transport Through the Membrane Surrounding Amniotic Fluid in the Rabbit

        Chang, Jin-Keun,Lee, Sang-Jin,Sung, Ho-Kyung The Korean Physiological Society 1993 대한생리학회지 Vol.27 No.1

        To study the regulation of amniotic fluid volume and electrolyte concentration by the Membranes surrounding the amniotic fluid, the rate of $Li^+$ disappearance from amniotic sac of expired fetuses were examined while increasing the amniotic volume and osmolarity in rabbits. After intraamniotic injection of 1 ml isosmotic saline (about 20% of the amniotic fluid volume) containing 15 mM LiCl and 0.5 g/L Censored, the time courses of $Li^+$ and Censored disappearance were determined. From there the $Li^+$ clearance through the extrafetal routes was estimated and compared with that obtained from living fetuses. The volume, $Na^+$ concentration and osmolarity of amniotic fluid were measured and their relationships with $Li^+$ disappearance were evaluated. The fellowing results were obtained: 1. The rate of disappearance from amniotic fluid of living fetuses during the first 30 minutes was strikingly higher for $Li^+$ than for Censored, suggesting that extrafetal routes exist. At 60 and 90 minutes, however, the disappearance rate of $Li^+$ was less than that of Censored, suggesting the possibility of $Li^+$ reentry through fetal urination. 2. The disappearance of $Li^+$ from the amniotic fluid of the expired fetus was substantial, although lower than that of living fetuses, throughout the experimental period. 3. The $Na^+$ concentration and the osmolarity of the amniotic fluid of expired fetus measured 30 minutes after an intraamniotic injection of isoosmotic saline showed wide variation, but thereafter they changed gradually towards the normal extracellular fluid level. 4. When the amniotic fluid was iso- or hyposmolar, the rate of $Li^+$ disappearance from the amniotic fluid of the expired fetuses showed little variation. However, when the amniotic fluid was hyperosmolar, the rate at 30 minutes was markedly lower than those of isosmotic or hyposmotic amniotic fluid. At 90 minutes, the rate of $Li^+$ disappearance in hyperosmolar fluid reached a similar level to the rate in isosmolar fluid. 5. The intraamniotic injection of 400 mOsm/L saline solution decreased the disappearance rate of $Li^+$ from expired fetuses, while the injection of mannitol into the maternal vein induced no significant change. From these results it is concluded that: 1) a significant amount of $Li^+$ may leave the amniotic fluid via filtration through the membranes surrounding the amniotic fluid, 2) during hyperosmolar challenge to amniotic fluid, osmotic bulk flow might counteract the filterable loss, and 3) $Li^+$ disappearance might continue even after the volume and osmolarity of the amniotic fluid have recovered to control values.

      • SCOPUSSCIEKCI등재

        재생 과정이 니켈-티타늄 호선의 물리적 성질과 표면 거칠기에 미치는 영향

        이성호,장영일 대한치과교정학회 2000 대한치과교정학회지 Vol.30 No.4

        본 연구의 목적은 재생된 니켈-티타늄 호선의 인장물성, 표면거칠기와 마찰력의 변화를 조사하여, 임상적으로 니켈-티타늄 호선을 재생하여 사용하는 것이 타당한지를 알아보는 것이다. 수종의 니켈-티타늄 호선과 스테인레스 스틸 호선을 처리전(T0: 대조군)과 인공타액에 4주간 처리한 군(T1), 그리고 인공타액 처리후 가압증기 멸균소독한 군(T2)으로 구분하여 인장실험과 주사전자현미경, 3D profilogram을 통한 표면거칠기의 변화와 마찰계수의 변화를 관찰하여 다음과 같은 결과를 얻었다. 1.인장실험을 하여 최대인장강도, 연신율, 탄성계수를 관찰한 결과 모든 니켈-티타늄 호선에서 재생과정 후에 대조군과 유의한 차이를 보이지 않았다(p〈0.05). 단 스테인레스 스틸 호선은 재생과정 후에 최대인장강도, 연신율, 탄성계수에서 통계적으로 유의한 변화를 보였다(p〈0.05). 2.주사전자현미경을 통한 관찰에서 재생후에 Sentalloy를 제외한 호선에서 표면의 점부식(pitting)과 압흔(indentation)이 증가하였다. 3.3D profilogram을 사용하여 관찰한 표면거칠기(Ra와 Rq)의 변화를 살펴보면, 재생과정 후에 Sentalloy를 제외한 NiTi, Optimalloy, 스테인레스 스틸 호선에서 통계적으로 유의하게 표면거칠기가 증가하였다(p〈0.05). 4.재생과정 후에 시행한 마찰력 실험에서는 최대운동마찰계수가 Sentalloy를 제외한 NiTi, Optimalloy, 스테인레스 스틸 호선에서 통계적으로 유의하게 증가하였다(p〈0.05). NiTi, Optimalloy의 표면거칠기와 마찰계수의 변화는 임상적으로 영향을 미칠 정도는 아니며, 결과적으로 니켈-티타늄 호선을 재생하면, 인장실험시의 물성과 표면거칠기, 마찰계수의 변화가 임상적으로 문제가 없을 것으로 생각된다. The purpose of this study was to investigate the change of mechanical properties, surface topography and frictional force of various nickel titanium wires after recycling. Three types of nickel-titanium wires and one type of stainless steel wire were divided to three groups: as-received condition(T0:control group), treated in artificial saliva for four weeks(T1) and autoclaved after being treated in artificial saliva(T2). Some changes were observed for the selected mechanical properties in tensile test, surface topography by means of SEM and 3D profilogram, and frictional coefficient. The findings suggest that: 1.Nickel-titanium wires demonstrated no statistically significant differences in maximum tensile strength, elongation rate and modulus of elasticity, but stainless steel wore demonstrated statistically significant differences in maximum tensile strength, elongation rate and modulus of elasticity between the groups(p〈0.05). 2.NiTi, Optimalloy, Stainless Steel wires demonstrated increased pitting and corrosion in SEM finding. 3.Recycled NiTi, Optimalloy and stainless steel wires demonstrated significantly greater surface roughness(Ra and Rq) through 3D profilogram when compared with the control wires(p〈0.05), but Sentalloy didn't demonstrate significant difference. 4.Recycled NiTi, Optimalloy and stainless steel wires demonstrated significantly greater maximum frictional coefficient when compared with the control wires(P〈0.05), but Sentalloy didn't demonstrate significant difference. The changes of surface roughness and frictional coefficient in NiTi and Optimalloy had no clinical implication, Consequently recycled nickel titanium wires demonstrated no clinical problem in tensile properties, surface topography and frictional coefficient.

      • KCI등재후보

        Er:YAG 레이저의 상아질 삭제효과 및 이에 따른 온도변화

        임광호,이창섭,이상호 대한소아치과학회 2001 大韓小兒齒科學會誌 Vol.28 No.1

        Er:YAG 레이저의 상아질 삭제효과와 이에 따른 온도변화를 평가하고자 발거된 소구치와 대구치로 상아세관내 조직액과 치수내압을 유지할 수 있는 상아질 시편을 제작하고 2.94㎛의 pulsed Er : YAG 레이저 (SDL-300EN, 삼성전자, 한국)를 handpiece형의 전달계를 이용한 비접촉식 방법으로 조사세기, pulse repetition rate, 조사시간, 물 분사여부 등의 조사조건을 달리하여 상아질 면에 조사하고 이때의 삭제량과 상아질 두께에 따른 온도변화, 그리고 삭제형태를 조사, 분석하여 다음과 같은 결과를 얻었다. 1.레이저 조사세기와 pulse repetition rate가 클수록, 그리고 조사시간이 길수록 삭제량이 증가되었다(P〈0.05). 그러나 5Hz의 pulse repetition rate에서는 조사시간에 따른 삭제 량의 차이가 크지 않았다. 2.삭제된 와동은 비교적 변연부가 명확하고 깨끗하였으며 와동의 바닥은 원추형이였으며 부드러웠다. 조사세기와 pulse repetition rate가 클수록, 그리고 조사시간이 길수록 와동의 상부 직경이 넓었으며 150mJ, 5Hz, 5sec에서는 와동변 연부에 약간의 crack이 관찰되었다. 3. 레이저 조사세기와 pulse repetition rate가 클수록, 그리고 조사시간이 길수록 상아질의 온도가 더 많이 상승하였으며 시편의 두께가 두꺼울수록 온도상승이 적었다(P〈0.05). 4.물을 분사하며 레이저를 조사할 경우 물을 분사하지 않은 경우에 비해 온도상승이 매우 감소되었다(P(0.05). 이상의 결과를 종합해 볼 때 Er : YAG레이저를 상아질에 조사할 경우 와동의 형태가 명확하고 물을 분사할 경우 온도상승이 많이 유발되지 않으므로써 삭제력이 좋고 치수에 유해작용이 없는 것으로 생각된다. 향후 임상에서 치질을 제거하는데 효율적으로 이용되기 위해서는 삭제력이 더욱 크고 이에 따른 온도상승을 최소로 할 수 있는 조사 시스템 및 방법에 대한 연구가 계속적으로 이루어져야 할 것으로 사료된다. The purpose of this study was to investigate the effects of Er : YAG laser on cutting efficacy and temperature changes of dentin. We used the dentin specimens of human premolars and molars which contain the physiologic saline and maintain the pulpal pressure in dentinal tubules. Each specimen was exposed to Er : YAG laser with non-contact handpiece type delivery system under different treatment condition of irradiation energy, pulse repetition rate, and exposure time. Two procedures were conducted by the presence of water flow during lasing. The specimens were grouped by thickness of dentin. We investigated the cavity pattern, volume, and temperature change of dentin specimen to determine the cutting efficacy and temperature rise of Er : YAG laser, and obtained following results. 1.Cutting volume of dentin was increased by increasing the irradiation energy, pulse repetition rate, and exposure time(P〈0.05). 2. Margins of abulated cavities were sharp and clean and floors of cavities were conical in shape and showing smooth surfaces. Upper diameter of abulated cavities were increasing as laser parameter of irradiation energy, pulse repetition rate, and exposure time were increased. A few cracks were observed on abulated surfaces under treatment condition of laser parameter with 150mJ, 5Hz, and 5sec. 3.Temperature was increased as laser parameter of irradiation energy, pulse repetition rate, and exposure time were increased, and temperature rise was decreased as dentin thickness was increased(P〈0.05). 4.Temperature rise was decreased under water flow compared with no water flow during laser exposure(P〈0.05). From these results, we think that the method of using a Er : YAG laser would be effective and safe in cutting dentin for clinical application.

      • 소아 고관절 병변에 대한 골주사의 임상적 의의

        박상원,허창룡,박정호 中央醫學社 1989 中央醫學 Vol.54 No.1

        The purpose of this study is to evaluate the possibility of bone scanning in early diagnosis of Legg-Perthes disease and transient synovitis of hip joint prior to radiological changes, and also to observe scintigraphic changes in early and late stage of Legg-Perthes disease. The authors observed the uptake ratio of technetium-99m-methylene diphosphonate and the scintigraphic findings in fifteen cases of Legg-Perthes disease and ten cases of transient synovitis of the hip joint. The obtained results were as follows: 1. In fifteen Legg-Perthes disease, scintigraphic findings showed three decreased uptake and one normal uptake in four cases without bone changes on the plain radiograph, and seven decreased uptake and four increased uptake in the eleven cases with bone changes. 2. In ten transient synovitis of the hip joint, scintigraphic findings showed four slight increased uptake but no changes in six cases. Above findings suggest that bone scanning is valuable diagnostic method in early stage of Legg-Perthes disease, but it has limited value in its advanced stage and has no value in transient synovitis of the hip joint.

      • UASB에 의한 染料化學工場 廢水處理

        김성우,임찬섭,박정호,성낙창,박승조 동아대학교 환경문제연구소 1996 硏究報告 Vol.19 No.1

        This study has been carried out to measuring the biodegradability and toxicity of dyes chemnical factory wastwwater for anaerobic treatment. The experiment consisted of batch test pilot plant test. The results are as follows 1. Biodegradability assays were conducted at two assay concentration for 2gCOD and 5gCOD tat BMP are respectively 0.23㎥CH₄/ ㎏.COD, 0.16㎥CH₄/㎏.COD respresents the noninhibited bioconversion efficency also MRR were 1.080 and 0.959 represented. 2. In pilot plant experiment, COD removal efficency are up 65% represented according to changing COD loading rate from 0.15㎏COD/㎥.d to 2.6㎏COD/㎥.d 3. Alkalinity and Volatile, VA/Alkalinity as chemical factor of anaerobic was 1070∼1700㎎/ℓ, 30∼150g/ℓ and 0.02∼0.09 respectively. 4. According to changing COD loading rate from 0.15㎏COD/㎥.d to 2.6㎏/COD/㎥.d the methane gas production was 0.20~0.23]㎥ CH₄/㎏.COD_(rem)

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