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배준한,주민석,고태국 연세대학교 대학원 1994 延世論叢 Vol.30 No.1
This thesis is a study on the quench characteristics in epoxy impregnated superconducting magnet. Teh normal 3one propagation velocity, full quench time and full recovery time in a superconducting magnet during quench are simulated numerically. Propagation velocity is linearly proportional to the transport current and abruptly increases near the critical current. Longitudinal velocity is nearly 20 times of transverse velocity regardless of the transport current. The ratio of the transverse velocity to longitudinal velocity is about 0.04 regardless of the transport current and the full quench time is abruptly decreased near the minimum propagation current. Comparing superconducting composites composed of Cu matrix to the composites of Cu/CuNi matrix, the propagation velocity of the former is slower than the latter, while the full quench time of the former is longer under the same transport curent.
이삼범,도호석,도병수,이창현,심민철,권굉보 대한응급의학회 1995 대한응급의학회지 Vol.6 No.2
Study Objectives : To investigate and resolve the problems related with ventilator management in ED(emergency department). At present the ventilator is essential equipment of ED on university hospital and emergency center in Korea. Design : Retrospective consecutive case series. Setting : University teaching hospital Type of participants : All patients admitted and recieved ventilator management in ED of yeungnam university hospital from Jan. 1994 to jul. 1995. Methods and interventions : Charts of all patients were reviewed to determine the frequency, the types and causes of respiratory failure, the death rate, the mean duration of admission, the complications, and CPR(cardiopulmonary resuscitation) related with ventilator management in ED. We also identified the problems related with ventilator management by ED physicians and nurses through the answers to seven questions that suggested by us about ventilator management in ED. Measurements and main result : There were 34,751 admissions through ED during the study period. Of these 160 patients managed with ventilator in ED. The frequency of ventilator management in ED is increased at 1995(0.73%) that compared with 1994(0.32%). Non-trauma(113 cases) and hypoxic respiratory failure(83 cases) patients are more common than trauma(37 cases) and ventilatory failure Total CPR rate related with ventilator management are 25.3%. The mean duration of admission are 12.56±20.28 days, and the death rates are 45.3%. The incidence of complications occurred during ventilator management in ED are 37 cases. About seven questions suggested by us to 30 ED staffs(ED physician, nurses and paramedics), most frequent answer is the difficulty of keeping ventilator in ED because other department rent ventilator from ED and lost a part of ventilator. Conclusion : As the use of ventilator in ED is increased the emergency physician should be well trained for the indications, complications, setting mode and general problems of machine occurred during ventilator management in ED patients.
이상형 스테인레스강의 크롬질화물 석출과 상 방위관계 연구
최병학,김진우,고석민,조용석,김상식,이재현 국립7개대학공동논문집간행위원회 2002 공업기술연구 Vol.2 No.-
Microstructures in the directionally solidified duplex stainless steels were investigated in order to understand the effect of nitrogen addition and its precipitation in the α phase. It was found that the addition of nitrogen causes the formation of fine precipitates in α matrix and segregation phases of nitrogen in the α/γ interface. Both the fine precipitates and the segregation phases were identified as CrN(fcc, a=4.18Å), as a coherent phase related to the α-bcc matrix with crystal relationship of (200) CrN//(01 ̄1)α and (1 ̄1 ̄1)CrN//(3 ̄2 ̄1)α.
대구 상인동 가스참사로 본 지역 응급의료체계에 대한 고찰
이삼범,도호석,도병수,이창현,심민철,권굉보 대한응급의학회 1995 대한응급의학회지 Vol.6 No.2
Disaster may be defined as a sudden calamitous event associated with great damage or destruction. A more common definition, among emergency-preparedness planners, is a medical occurrence that overwhelms medical care systems and facilities. Most regional disaster plans are formulated to respond to disasters of moderate size. At 07:50 A.M. on 28 April 1995, gas explosion was happened at Sangin-Dong where was going to be under construction of subway in Taegu, Korea. 102 victims had died and 178 victims had moderate or minor injuries. Problems in the organization at the scene, triage, field management, transport to the hospital, and the communication contributed to the confusion in the management of victims. An analysis of this disaster allows several lessons to be learn about perimeter control, command functions, crowd control, and transportation priorities. It will benefit disaster planners in other communities.
방향성 응고된 이상형 스테인레스강에서 질소첨가가 미세조직에 미치는 영향
최병학,정병길,김진우,고석민,이재현,김상식,김성준 국립7개대학공동논문집간행위원회 2001 공업기술연구 Vol.1 No.-
Microstructures in the directionally solidified duplex stainless steels were investigated in order to understand the effect of nitrogen addition. It was found that the addition of nitrogen causes formation of fine precipitates in a matrix and segregation phases of nitrogen in the α/γ interface. Both the fine precipitates and the segregation phases were identified CrN(fcc, a=4.16A˚), which has the coherent phase relationship with bcc α matrix of (200) CrN // (0 1 ̄ 1) α and (1 ̄1 ̄ 1) CrN // ( 3 ̄ 2 ̄ 1) α.
Effect of human endogenous retrovirus-K env gene knockout on proliferation of ovarian cancer cells
Ko Eun-Ji,Kim Eun Taeg,Kim Heungyeol,Lee Chul Min,Koh Suk Bong,Eo Wan Kyu,Kim Hongbae,Oh Young Lim,Ock Mee Sun,Kim Ki Hyung,Cha Hee-Jae 한국유전학회 2022 Genes & Genomics Vol.44 No.9
Background: Among various human endogenous retroviruses (HERVs), the HERV-K (HML-2) group has been reported to be highly related to cancer. In pancreatic cancer cells, shRNA-mediated downregulation of HERV-K env RNA decreases cell proliferation and tumor growth through the RAS-ERK-RSK pathway; in colorectal cancer, CRISPR-Cas9 knockout (KO) of the HERV-K env gene affects tumorigenic characteristics through the nupr-1 gene. Objective: The effect of HERV-K env KO has not been studied in ovarian cancer cell lines. In this study, we analyzed the tumorigenic characteristics of ovarian cancer cell lines, including cell proliferation, migration, and invasion, and the expression patterns of related proteins after CRISPR-Cas9 KO of the HERV-K env gene. Methods: The HERV-K env gene KO was achieved using the CRISPR-Cas9 system in ovarian cancer cell lines SKOV3 and OVCAR3. Tumorigenic characteristics including cell proliferation, migration, and invasion were analyzed, and related protein expression was investigated by western blot analysis. Results: The expression of the HERV-K env gene in KO cells was significantly reduced at RNA and protein levels, and tumorigenic characteristics including cell proliferation, migration, and invasion were significantly reduced. In HERV-K env KO SKOV3 cells, the expression of the RB protein was significantly up-regulated and the cyclin B1 protein level was significantly reduced. In contrast, in HERV-K env KO OVCAR3 cells, the level of phospho-RB protein was significantly reduced, but other protein levels were not changed. Conclusion: The results of this study showed that HERV-K env gene KO affects cell proliferation, invasion, and migration of ovarian cells through RB and Cyclin B1 proteins, but the specific regulation pattern can differ by cell line.
P183 Assessment of quality of life in patients with nail diseases in Korea
( Min-young Yang ),( Kyung-min Lim ),( Hyunju Jin ),( Hyang-suk You ),( Woo-haing Shim ),( Jeong-min Kim ),( Gun-wook Kim ),( Hoon-soo Kim ),( Hyun-chang Ko ),( Byung-soo Kim ),( Moon-bum Kim ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.2
<div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div> Background: Nail diseases have considerable emotional impact and may limit activity by impairing functionality of both fingers and toes Objectives: To assess the influences of nails diseases on quality of life (QOL) in Koreans Methods: 135 patients with nail diseases completed an questionnaire on QOL (Dermatology Quality of Life Index, DLQI). The subjects were classified into subgroups according to sex, age, number of nails involved, nail area affected, duration of nail disease, specific diseases (e.g. onychomycosis, psoriatic nail and etc.) and groups of diseases (e.g. traumatic, infectious, and etc.). Statistical analysis was carried out using T-test, ANOVA analysis to compare the values between subgroups Results: Comparison between various disease groups showed a statistically significant higher impact for traumatic, infectious, inflammatory and structural diseases and a lower impact for pigmentary diseases. QOL was statistically significantly more affected in patients having multiple involved nails, women, widely affected nail area, longer duration of diseases and in people aged 60-79 years. There was no statistically significant difference on QOL impact between patients having only fingernails or toenails involved Conclusion: Even though published literature tends to focus on the impact of nail psoriasis and onychomycosis on QOL, other nail diseases induced similar frustration to patients. Dystrophic appearance of the nails has a significant influences on patients irrespective of diseases