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Venkata Subramanian Krishnaraju,Kumar Rajender,Sood Ashwani,Jaya Shukla,Karthikeyan Subramanian,Nandita Kakkar,Naresh Panda,Mittal Bhagwant Rai 대한핵의학회 2021 핵의학 분자영상 Vol.55 No.3
Chondrosarcoma is a cartilaginous tumor of mesenchymal origin. The histology and grade of the tumor determine the chances of relapse and survival. These tumors usually respond poorly to chemo-radiotherapy in cases of non-resectable and recurrent disease. 18F-FDG PET/CT has been used in evaluation of recurrence. However, these tumors show only mild to moderate FDG avidity due to their lower mitotic activity and large acellular matrix. These tumors are known to have a high degree of angiogenesis, especially in those of higher grade. We present a case of a 53-year-old man with grade II chondrosarcoma of the left femur showing only mild avidity on 18F-FDG PET/CT but showing moderate to intense tracer avidity on 68Ga-DOTA-RGD2 PET/CT. This may enable the use of angiogenesis-targeted positron and beta-emitting radiopharmaceuticals as a potentially new theranostic alternative treatment in cases of refractory metastatic chondrosarcoma.
THE DIFFERENCE ORLICZ SPACE OF ENTIRE SEQUENCE OF FUZZY NUMBERS
Subramanian, Nagarajan,Esi, Ayhan Korean Mathematical Society 2010 대한수학회논문집 Vol.25 No.2
In this paper we define and study the difference Orlicz space of entire sequence of fuzzy numbers. We study their different properties and statistical convergence in these spaces.
Subramanian, Vijayanand,Jeong, Dae-Woon,Han, Won-Bi,Jang, Won-Jun,Shim, Jae-Oh,Bae, Jong Wook,Roh, Hyun-Seog The Royal Society of Chemistry 2014 NEW JOURNAL OF CHEMISTRY Vol.38 No.10
<P>A rapid one step direct synthesis of high temperature water gas shift (HT-WGS) catalysts, magnetite incorporated with various promoters like Cu, Ni, Zn, and Co, has been shown. The key achievements in this work, in terms of catalyst preparation, are as follows: (1) direct synthesis of magnetite, a catalytically active phase in HT-WGS reaction, (2) easy incorporation of various transition metal promoters like Cu, Ni, Zn, and Co, (3) rapid preparation without any washing step by using an ample amount of solvent, and (4) a simplified procedure by avoiding longer digestion time and any specific pH value. To achieve this, an amino acid, glycine, was used as a complexing agent as well as a fuel for the auto-combustion process. The zwitterionic nature of glycine favors the easy incorporation of the promoter metal ions. In addition, the reducing atmosphere created by glycine during its burning makes it possible to prepare magnetite directly. During the HT-WGS reaction, the activity follows the order Cu-FAG > Ni-FAG > Zn-FAG > Co-FAG. The optimization of the Cu promoter is also carried out. At 12.5 mol% of Cu loading the catalytic activity reached a CO conversion value of 87% at 400 °C.</P> <P>Graphic Abstract</P><P>A rapid, simple, facile, and cost effective synthetic methodology was proposed for the direct synthesis of magnetite catalysts for high temperature water gas shift reaction. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c4nj00854e'> </P>
Subramanian Kalyanaraman,Rajapandi Vettumperumal,Rajalingam Thangavel 한국물리학회 2013 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.62 No.5
Undoped and lithium-doped zinc oxide (ZnO) thin films have been deposited on sapphire substrates (0001) using the sol-gel method. The effect of doping with various percentages of Li ata particular annealing temperature of 600 ℃ is studied. The samples are characterized using Xray diffraction (XRD), scanning electron microscopy (SEM), micro-photoluminescence (μ-PL) and Raman and polarized Raman (PR) spectroscopy. The X-ray diffraction and micro-Raman spectroscopy confirm the presence of lithium substitution for zinc. The wurtzite structure of the lattice is retained, and five multiple phonon Raman modes are observed. The values of the depolarization ratios are calculated from polarized Raman data. Photoluminescence shows a strong emission peak in the near UV at 3.276 eV and negligible visible emission. The PL peak positions in the doped samples nearly coincide with each other, suggesting very similar recombination mechanisms in the nanocrystals.
Subramanian, Advait,Capalbo, Anita,Iyengar, Namrata Ravi,Rizzo, Riccardo,di Campli, Antonella,Di Martino, Rosaria,Lo Monte, Matteo,Beccari, Andrea R.,Yerudkar, Amol,del Vecchio, Carmen,Glielmo, Luigi Cell Press 2019 Cell Vol. No.
<P><B>Summary</B></P> <P>Maintaining the optimal performance of cell processes and organelles is the task of auto-regulatory systems. Here we describe an auto-regulatory device that helps to maintain homeostasis of the endoplasmic reticulum (ER) by adjusting the secretory flux to the cargo load. The cargo-recruiting subunit of the coatomer protein II (COPII) coat, Sec24, doubles as a sensor of folded cargo and, upon cargo binding, acts as a guanine nucleotide exchange factor to activate the signaling protein Gα12 at the ER exit sites (ERESs). This step, in turn, activates a complex signaling network that activates and coordinates the ER export machinery and attenuates proteins synthesis, thus preventing large fluctuations of folded and potentially active cargo that could be harmful to the cell or the organism. We call this mechanism AREX (autoregulation of ER export) and expect that its identification will aid our understanding of human physiology and diseases that develop from secretory dysfunction.</P> <P><B>Highlights</B></P> <P> <UL> <LI> ER exit sites are endowed with an auto-regulatory signaling complex called AREX </LI> <LI> The COPII subunit Sec24 senses folded cargo and activates the AREX signaling network </LI> <LI> AREX responds to folded cargo fluxes by regulating cargo export and protein synthesis </LI> <LI> AREX maintains potentially harmful folded cargo in the ER at steady low levels </LI> </UL> </P> <P><B>Graphical Abstract</B></P> <P>[DISPLAY OMISSION]</P>
Subramanian Gopalakannan,Thiagarajan Senthilvelan 대한기계학회 2014 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.28 No.3
A novel aluminium metal matrix composite reinforced with SiC particles were prepared by liquid metallurgy route. Recent developmentsin composites are not only focused on the improvement of mechanical properties, but also on machinability for difficult-tomachineshapes. Electrical discharge machining (EDM) was employed to machine MMC with copper electrode. using EDM. Experimentswere conducted using pulse current, gap voltage, pulse on time and pulse off time as typical process parameters. The experimentplan adopts face centered central composite design of response surface methodology. Analysis of variance was applied to investigate theinfluence of process parameters and their interactions viz., pulse current, gap voltage, pulse on time and pulse off time on material removalrate (MRR), electrode wear ratio (EWR) and surface roughness (SR). The objective was to identify the significant process parametersthat affect the output characteristics. Further a mathematical model has been formulated by applying response surface method inorder to estimate the machining characteristics such as MRR, EWR and SR.
Subramanian, Dharaneedharan,Kim, Min-Sun,Kim, Dong-Hwi,Heo, Moon-Soo SciELO 2017 Brazilian archives of biology and technology Vol.60 No.-
<P>Present study aim to evaluate the antimicrobial, antioxidant and cytotoxic potential of crude extract of Marine Streptomyces carpaticus MK-01 isolated from seawater collected from Daejeong-cost of Jeju Island. About 24 actinomycetes strains were isolated and subjected to morphological and molecular analysis that confirmed the isolate as S. carpaticus MK-01. Crude ethyl acetate extract of MK-01 strain showed extensive antibacterial activity against Gram-positive fish pathogenic bacteria namely Streptococcus iniae and S. parauberis with a maximum zone of inhibition (0.92 +/- 0.03mm) was recorded against S. parauberis at the minimum extract concentration (3.12 mu g/ml). The MK-01 ethyl acetate extract shows dose dependant significant increase in antioxidant activity. The 50% cytotoxic concentration (CC50) of MK-01 ethyl acetate extract was attained at 53.71 mu g/ml and the effective concentration 50 (EC50) against virus-infected Epithelioma papulosum cyprini cell lines was 8.72 mu g/ml of S. carpaticus MK-01 crude ethyl acetate extract.</P>
Subramanian Ganesh,Ramachandran Amutha 한국통신학회 2013 Journal of communications and networks Vol.15 No.4
Advances in wireless sensor network (WSN) technology have enabled small and low-cost sensors with the capability of sensing various types of physical and environmental conditions, data processing, and wireless communication. In the WSN, the sensor nodes have a limited transmission range and their processing and storage capabilities as well as their energy resources are limited. A triple umpiring system has already been proved for its better performance inWSNs. The clustering technique is effective in prolonging the lifetime of theWSN. In this study, we have modified the adhoc on demand distance vector routing by incorporating signal-tonoise ratio (SNR) based dynamic clustering. The proposed scheme,which is an efficient and secure routing protocol for wireless sensor networks through SNR-based dynamic clustering (ESRPSDC)mechanisms, can partition the nodes into clusters and select the cluster head (CH) among the nodes based on the energy, and non CH nodes join with a specific CH based on the SNR values. Error recovery has been implemented during the inter-cluster routing in order to avoid end-to-end error recovery. Security has been achieved by isolating the malicious nodes using sink-based routing pattern analysis. Extensive investigation studies using a global mobile simulator have shown that this hybrid ESRP significantly improves the energy efficiency and packet reception rate as compared with the SNR unaware routing algorithms such as the low energy aware adaptive clustering hierarchy and power efficient gathering in sensor information systems.