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Thanseer, N.T.K.,Bhadada, Sanjay Kumar,Sood, Ashwani,Parihar, Ashwin Singh,Dahiya, Divya,Singh, Priyanka,Basher, Rajender Kumar,Das, Ashim,Mittal, Bhagwant R. 대한핵의학회 2018 핵의학 분자영상 Vol.52 No.2
$^{18}F$-Fluorocholine (FCH) PET/CT is evolving as a functional imaging modality for the preoperative imaging of abnormal parathyroid tissue(s) helping to localize eutopic and ectopic parathyroid tissue and limit the extent of surgery. FCH PET/CT may show incidental uptake in various thyroid lesions necessitating further evaluation, whereas the role of $^{18}F$-fluorodeoxyglucose (FDG) PET/CT in the detection of incidental thyroid nodules is well documented. The case of a middle-aged woman with dual pathology of parathyroid adenoma and papillary thyroid cancer detected on FCH and FDG PET/CT is presented.
Incidental Muscle Uptake of 177 Lu-DOTATATE in Peripheral Vascular Disease
Piyush Aggarwal,Kunal Ramesh Chandekar,Ashwani Sood,Shakti Zerial,Rajender Kumar,Anindita Sinha 대한핵의학회 2021 핵의학 분자영상 Vol.55 No.6
Somatostatin receptor (SSTR)-based imaging and therapy has emerged as well-established modality in neuroendocrinetumors. However, its role in inflammation imaging is still evolving. We present a 48-year-old male with metastatic neuroendocrinetumor who underwent lutetium-177-based somatostatin receptor-based therapy. The post-therapy scan showed afocal tracer uptake in the left calf muscle in addition to the expected tracer uptake at the primary and metastatic sites. Further,cross-sectional imaging and biochemical investigations revealed peripheral vascular disease (PVD). The incidental traceruptake in the calf on post-therapy scan potentiates the role of somatostatin receptor scintigraphy in identifying macrophagespecificinflammatory reactions.
Venkata Subramanian Krishnaraju,Kumar Rajender,Sood Ashwani,Jaya Shukla,Karthikeyan Subramanian,Nandita Kakkar,Naresh Panda,Mittal Bhagwant Rai 대한핵의학회 2021 핵의학 분자영상 Vol.55 No.3
Chondrosarcoma is a cartilaginous tumor of mesenchymal origin. The histology and grade of the tumor determine the chances of relapse and survival. These tumors usually respond poorly to chemo-radiotherapy in cases of non-resectable and recurrent disease. 18F-FDG PET/CT has been used in evaluation of recurrence. However, these tumors show only mild to moderate FDG avidity due to their lower mitotic activity and large acellular matrix. These tumors are known to have a high degree of angiogenesis, especially in those of higher grade. We present a case of a 53-year-old man with grade II chondrosarcoma of the left femur showing only mild avidity on 18F-FDG PET/CT but showing moderate to intense tracer avidity on 68Ga-DOTA-RGD2 PET/CT. This may enable the use of angiogenesis-targeted positron and beta-emitting radiopharmaceuticals as a potentially new theranostic alternative treatment in cases of refractory metastatic chondrosarcoma.
Sensitive Detection of a Small Parathyroid Adenoma Using Fluorocholine PET/CT: A Case Report
Thanseer N. T. K. Padinhare-Keloth,Sanjay K. Bhadada,Ashwani Sood,Rajender Kumar,Arunanshu Behera,Bishan D. Radotra,Bhagwant R. Mittal 대한핵의학회 2017 핵의학 분자영상 Vol.51 No.2
Primary hyperparathyroidism is caused by parathyroidadenoma in the majority of cases and diagnosis is usuallymade biochemically. Pre-surgical localization of parathyroidadenoma is essential to limit the extent of surgery and avoidmissing them at ectopic sites. Anatomical and functional imagingare used for the localization, but may fail to identify thesmall and ectopic parathyroid adenoma. We present a case ofsmall sized ectopic parathyroid adenoma at unusual locationdetected by F-18 fluorocholine (FCH) PET/CT, where otherimaging modalities failed. The post-operative histopathologyconfirmed the diagnosis of ectopic parathyroid adenoma.
Shelvin Kumar Vadi,Devendra Kumar Chouhan,Arun Kumar Reddy Gorla,Jaya Shukla,Ashwani Sood,Bhagwant Rai Mittal 대한핵의학회 2017 핵의학 분자영상 Vol.51 No.3
Primary synovial osteochondromatosis (PSOC) is a rare but clinically significant cause of morbidity especially in the male population. Surgery is the primary treatment of choice, but the recurrence rate is reported to be high. Moreover, the presence of widespread loose bodies makes it a cumbersome procedure. The complete removal of the disease is tough at times and results in early recurrence. Radiosynovectomy is an established technique for treating various joint arthropathies. The role of radiosynovectomy in case of PSOC has not yet been explored. This case report described the case of a young male with PSOC of the knee joint who was treated with radiosynovectomy for pain relief. The patient reported complete relief from the pain along with significant improvement in joint mobility. The post-therapy three-phase bone scan also validated the reduction in joint inflammation. The patient was taken for surgical removal of the redundant loose bodies after a significant improvement in the pain and reduction in inflammation. Post-therapy radiation fibrosis of the synovium also helped in the en bloc removal of the disease. The role of radiosynovectomy in PSOC needs to be further explored concerning its potential role as an adjuvant to surgical procedures.
Jain Tarun Kumar,Singh Harmandeep,Kumar Rajender,Bal Amanjit,Sood Ashwani,Mittal Bhagwant Rai 대한핵의학회 2020 핵의학 분자영상 Vol.54 No.5
Pulmonary blastoma (PB) is a rare thoracic malignancy and preoperative diagnosis is challenging. A young man presented with dyspnea and chest pain for 3–4 months and chest-computed tomography (CT) revealed large mass in the left lung upper lobe and pleural effusion. Repeated CT-guided fine-needle aspiration cytology from the lesion and pleural fluid aspiration was negative for malignancy. F-18-fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET-CT) revealed heterogeneous tracer avidity in left lung mass with areas of necrosis. Real-time PET-CT-guided biopsy from metabolically active component of the lesion revealed biphasic PB on histopathology.