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      • Solar urticaria in Korean patients

        ( Sung Min Kim ),( Young Ah Cho ),( Ji Su Lee ),( Ji Youn Hong ),( Jin Hee Kim ),( Joo Ran Hong ),( Hye In Cheon ),( Yang Won Lee ),( Yong Beom Choe ),( Kyu Joong Ahn ) 대한피부과학회 2020 대한피부과학회 학술발표대회집 Vol.72 No.1

        Background: Solar urticaria (SU) is an uncommon type of photodermatoses characterized by erythematous wheal with pruritus after sunlight exposure, which shows a female predominance. Only a few studies to analyze the clinical features of SU were reported in Asia. Objectives: We aimed to analyze the clinical and photobiological characteristics of SU in Korea. Methods: We retrospectively investigated the medical records of patients with SU who visited the department of dermatology, Konkuk university medical center from January 2005 to January 2020. Results: Of a total of 44 patients, 36 (81.8%) were male and 8 (18.2%) were female. The mean age at onset was 17.6 years (range, 5-47) and the mean threshold time was 19.7 minutes. Among 32 patients who underwent phototesting, the action spectrum most commonly implicated was ultraviolet (UV) A only in 12 (37.5%), and then visible light (415nm) only was responsible for SU in 8 (25.0%). Three patients (9.4%) were induced by both UVA and visible light (415nm). Even 4 patients (12.5%) were triggered by only natural sunlight. Serum immunoglobulin E levels were measured in 33 patients, and 17 (51.5%) showed values higher than normal. The treatment most widely used were oral antihistamine (43.2%), followed by phototherapy (13.6%). Conclusion: SU is a rare photodermatosis in Korea, which shows a male preponderance. In this study, UVA and visible light (415nm) were predominant action spectrum of SU.

      • SCIESCOPUSKCI등재
      • SCOPUSKCI등재

        축산 폐수의 효율적 처리를 위한 광합성 미세조류인 Spirulina platensis 배양 공정의 최적화

        안주희,김성수,김태호,이준엽,오상집,이진하,이현용 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.4

        돈분 폐수의 효율적인 처리를 위해 6 W/㎡, 12 W/㎡와 24 W/㎡의 조도 하에서 온도를 15℃에서 40℃까지 각각 변화시켜, 광합성 미세 조류인 Spirulina platensis의 생육에 관한 최적 생육 조건 결정에 관한 실험을 하였다. 균체의 비생육속도는 30℃까지는 온도 증가에 따라 증가하였다. 균체의 생육에 있어서 온도의 영향을 설명하기 위해서 Arrhenius 식을 이용하여서 얻은 활성화 에너지 값은 13.5kal/mol이었다. 순수 배지에서 배양된 균체의 비생육속도가 0.31(1/day)인 반면 30% 돈분 첨가 배양시 얻은 균체의 비생육속도는 0.24(1/day)였다. 폐수내의 총 질소량과 이의 제거속도로 균체의 폐수 처리 능력을 평가할 수 있었다. 돈분 농도를 달리 첨가한 회분배양에 있어서 70~93%(PO_4^3- -P), 67~93%(inorganic nitrogen), 80~90% (COD) 그리고 37~56%(organic nitrogen)의 감소율을 보였다. 총-질소와 총-인의 1차반응 감소 속도 상수는 각각 0.17(1/day)와 0.14(1/day)로 계산되었다. 20% 돈분을 첨가하는 연속배양에 있어서 회석률이 0.20(1/day)일 때 최대 균체농도가 1.52(g/L)를 유지했다. 돈분처리 후 얻은 균체의 성분은 단백질이 58.7%, 지방 11.0% 그리고 회분이 15.6%였다. The kinetics of growing microalga, Spirulina platensis was investigated to treat swine wastes with optimum growth conditions. Temperature was varied from 15 to 40℃ at three different light intensities, 6 W/㎡, 12 W/㎡ and 24 W/㎡. The specific growth rate was increased as temperature increased up to 30℃. The activation energy was estimated as 13.5 kcal/mol by an Arrhenius relationship. 0.24(1/day) of specific growth rate was obtained from batch cultivation with 30% swine wastes, compared to 0.31 (1/day) from clean culture. It was found that Spirulina platensis was able to reduce 70~93% of PO_4^3- -P, 67~93% of inorganic nitrogen, 80~90% of COD and 37~56% organic nitrogen by adding various concentrations of swine wastes for 12 days of batch cultivation. Rate constants for removing nitrates and phosphates in treating swine wastes were estimated as 0.17 (1/day) and 0.14 (1/day) in the first order reaction, respectively. 1.52(g/L) of maximum cell density was maintained at 0.20(1/day) of dilution rate in continuous culture, adding 20% swine wastes for 30 days. The chemical composition of the biomass obtained from the process showed 58.7% of protein, 11.0% of lipid and 15.6% of ash.

      • 도시 노숙자의 주요 정신장애에 관한 역학 연구

        안준호,홍진표,유제춘,박종익,이철,한오수 大韓神經精神醫學會 2001 신경정신의학 Vol.40 No.2

        외환위기 이후 대도시를 중심으로 노숙자들이 급증하여 이들이 심각한 사회문제로 등장하였다. 외국의 연구에 의하면 노숙자 중 상당수가 만성 정신질환을 앓고 있으며, 정신질환이 노숙의 원인 및 예후와 밀접한 관련이 있다고 한다. 그러나 국내에서는 아직 노숙자의 정신장애의 유병률에 관하여 알려진 바 없으므로 이에 대하여 조사하였다. 방법: 1998년 말부터 1999년 초까지 부산지역의 쉼터 두 곳에 거주하는 노숙자 216명을 대상으로 인구학적 자료에 대한 설문조사를 한 뒤 Structured Clinical Interview for DSM-Ⅳ(SCID)을 이용하여 Axis Ⅰ의 주요 정신장애를 진단하였다. 이들의 정신장애의 평생유병률 및 현재유병률을 국내 일반인구 및 외국 노숙자의 정신장애의 유병률과 비교하였다. 결과: DSM-Ⅳ Axis Ⅰ의 정신장애 중 기분장애, 정신병적 장애, 물질사용장애에 대한 진단 평가 결과 상기 정신장애의 전체 평생유병률은 60.1%, 현재유병률은 35.7%이었다. 그 중 주요우울장애의 평생유병률 이 22.5%로서 외국의 노숙자에 대한 역학연구 결과와 비교해 볼 때 높은 수준이었고 알코올 사용 장애의 평생유병률은 47.4%이었다. 정신병적 장애의 평생유병률은 3.8%이었고, 그 중에서도 정신분열병의 평생유병률은 1.9%이어서 외국의 노숙자에 대한 연구결과보다 낮은 편이었다. 결론: 국내 노숙자에서 기분장애와 물질사용장애가 주된 정신장애였으며 정신분열병 등 정신병적 장애의 유병률은 외국에 비해 낮은편이었다. 이러한 정신장애를 가지고 있는 노숙자에 대하여 접근하고 치료하기 위한 대책이 마련되어야 할 것이다. Objective:As homeless people increased in urban areas after the economic crisis in Korea, they became a serious social problem. Foreign research showed that many homeless people had chronic mental illnesses which were closely related with the cause and prognosis of homelessness. But very little was known about the prevalence of mental disorders in Korean homeless people. This study tried to capture the overall picture of mental disorders in homeless people. Method:The study subjects were 216 homeless people who stayed at two Pusan shelters between late 1998 and early 1999. Questionnaires on sociodemographic data were administered to the subjects, and then diagnoses of major DSM-IV Axis I mental disorders were made using Structured Clinical Interview for DSM-IV Axis I Disorders(SCID). The lifetime and current prevalence of mental disorders in this study were compared to those from other studies in Korean general population and in foreign homeless people. Results:The lifetime prevalence of major DSM-IV mental disorders(mood disorders, psy-chotic disorders, and substance use disorders) of 216 homeless people was 60.1%, and current prevalence was 35.7%. The lifetime prevalence of major depressive disorders was 22.5% which was higher than that of foreign studies. The lifetime prevalence of alcohol use disorder was 47. 4%. The lifetime prevalence of psychotic disorders was 3.8%, and among them the lifetime prevalence of schizophrenia was 1.9% which was lower than that of foreign studies. Conclusions: In Korean homeless people, mood disorders and substance use disorders were the main mental disorders and psychotic disorders such as schizophrenia were less than in foreign homeless people. The plans to approach and treat homeless people with mental disorders should be made.

      • KCI등재

        비평적 주체의 정체성에 대한 연구 : 최재서의 경우를 중심으로 around Choi Jae-Seo

        안수진 한국문학교육학회 1999 문학교육학 Vol.3 No.-

        The aim of this thesis is to search 'critical subject formation' through criticism of Choi Jae-Seo in criticism education. Criticism of Choi shows interesting phrase with regard to modernity in Korean society. He was born in 1908, and was chosen as English teacher at Keong-sung Empire University(경성제국대학) in 1933. He was excellent critic, specially at grasping criticism trend in western culture. His interest as critic couldn't set apart from trend in western culture, and he concentrated upon problem of modernity. He considered characteristic of modern society as anxiety, disorder, confusion, and modern criticism as intellectual response to this. So he much attached importance to correctness of knowledge, because knowing anything correctly is important to researcher. But that is problematic attitude, because criticism always has certain premise, criticism couldn't help being accompanied with value indispensably. But his attitude itself means as countermove to trend in those days(so called 'criticism field' in terms of Bourdieu), so to speak, 'abuse criticism'(욕설비평). We could consider criticism as a kind of value system, so understanding that system is much valuable to grasp meaning factor of Choi. His criticism could be separated into two types. One type general, the other specific(applicated to Korean modern novel), or One type made and announced in Japan, the other in Korea. Choi summarized Korean life to cultural poverty, specially in 'Expansion and deepening in Realism', he brought to notice self-satire of Lee sang. He was intelligent critic, but his way of thinking had several limitations. Modernity he grasped was a kind of contemporaneous-ness. But his problematic frame itself shows agony and measure in Korea, in case of specific modernity. We should attend to this phrase in modern literature class, because our students' cultural identity couldn't be separated from this phrase.

      • 내부에 피라미드 구조를 가지는 ISB 판넬의 정적 특성 분석

        안동규,이상훈,김민수,한길영,김진석,정창균,양동열 한국공작기계학회 2005 한국공작기계학회 춘계학술대회논문집 Vol.2005 No.-

        The objective of this research work is to investigate into static characteristics of ISB panels with the pyramidal structure as a internally structured material. In order to investigate the behavior of material deformation and frracture characteristics, several tensile tests have been carried out for the ISB panel and skin sheet. Through the results of the experiments, the mechanical properties of ISB panel and skin sheet and fracture characteristics have been obtained. In addition, the mechaical properties of the ISB panel have been compared with that of the skin sheet by the view point of a specific modulus, a specific yield strength and a specific strength. From the results of the comparision, it has been shown that the ISB panel has an excellent static characteristics.

      • KCI등재

        실험적으로 유도된 당뇨백서의 심근병증에 관한 조직병리학적 연구

        안진수,이재훈 大韓顎顔面成形再建外科學會 1996 Maxillofacial Plastic Reconstructive Surgery Vol.18 No.3

        Diabetes mellitus revealed a chronic disorder of lipid, carbohydrate and protein metabolism characterized by insulin deficiency, and a striking tendency toward development of atherosclerosis, microangiopathy, nephropathy, neuropathy and recently cardiomyopathy etc. The mechanism of heart failure in patients with diabetic cardiomyopathy is not clear but diabetic cardiomyopathy usually occurs in persons with long standing diabetes. After diabetes induced in made Sprague- Dawley strain rats by injection of streptozotocin(60mg/kg), cardiac tissue with hematoxylin-eosin and Masson's trichrome stain was examined at 3 days, 1, 2, 4, 6 weeks later under light microscope. The results were obtained as follows : 1. In H&E stain of control group, myocardiac cells were shorter than skeletal muscle cell, which was branched out and connected each other at terminal with striation, intercalated disk and nucleus at center of cell. 2. In MT stain of control group, a few of collagen fibrile were seen at periva interstium, but wasn't seen between skeletal muscle fiber, and cardiac muscle was seen in various size. 3. In MT stain of experimental group, increased collagen fiber deposition at perivascular interstiums were seen periodically. 4. In MT stain of experimental group, increased collagen fiber deposition at interstitial matrix between perimyocardiac cells were seen at 3 day, 4 weeks and 6 weeks after DM induction. 5. In H&E stain of experimental group, partial degeneration of myocardiac cells was seen after 4 weeks of DM induction. From above results, streptozotocin induced diabetes mellitus increased collagen around perivascular and between intercellular matrix in heart.

      • 神闕의 穴位 특징과 鍼灸治療에 대한 문헌 고찰

        안성훈,조명수,송재수,도진우,김종성,손인철 한국전통의학연구소 2002 한국전통의학지 Vol.12 No.1

        This study was designed to investigate the location of Sin-Guel(CV_(8), 神闕) through literature research. We extracted the part about the location of Sin-Guel(CV_(8), 神闕) from ancient and modern oriental medical literature which were used commonly in clinic. The results were summarized as follows; 1. The location of Sin-Guel(CV_(8), 神闕) were generally recorded DangJeJung. 2. Sin-Guel(CV_(8), 神闕) placed in middle of linea alba. 3. Treatment effect of moxibustion on Sin-Guel(CV_(8), 神闕) were recorded as diarrhea, dropsy, prolapse of the anus, stomachache, paralysis etc.. 4. Acupuncture therapy on Sin-Guel(CV_(8), 神闕) is dangerous because of inflammation, it is suggested that acupuncture therapy may be possible if acupuncture therapy do not induce inflammation on Sin-Guel(CV_(8), 神闕).

      • KCI등재후보

        Propofol 정맥 주사 시 Metoclopramide의 통증 완화 효과

        김수진,박은지,안승원,김웅,김미운,임현술 대한마취과학회 2002 Korean Journal of Anesthesiology Vol.43 No.5

        Background: Propofol is a good induction agent. but it has a disadvantage of pain on intravenous injection. Pretreatment of metoclopramide or lidocaine have been reported to reduce pain on injection. thus, we have evaluated the quantity and quality of anagesic effect of metoclopramide and lidocaine. We observed differences in quality of pain according to venous cannula sizes and intravenous injection sites as well as nausea and vomiting in the postoperative state. Methods: Eighty patients scheduled for an elective operation by general anesthesia were chosen according to ASA (Ⅰ or Ⅱ) and divided into four groups randomly. Each group was injected through venous cannulas with normal saline (control group), metoclopramide 5 mg (group 1), netoclopramide 10 mg (group 2), or 2% lidocaine 40 mg (group 3) respectively. Then, propofol was injected of a 2 mg/kg dose with 0.5 ml/sex to all groups and we asked questions about injection pain after 10 seconds. Results: Pain relief was shown in all groups compared with the control. but metoclopramide 10 mg and lidocaine 40 mg pretreatment groups showed significant pain reief. Pain was relieved significantly when the drug was injected in the antecubital area. Postoperative nausea and vomiting were not observed. Conclusions: Metoclopramide 10 mg or lidocaine 40 mg pretreatment to induction by propofol revealed a good analgesic effect for propofol injection pain. (Korean J Anesthesiol 2002; 43: 558~565)

      • KCI등재

        치료환경에 따른 만성정신질환자의 삶의 질

        배 안,김진학,박수희,김명규,김중원 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.6

        연구목적: 일 지역사회(나주시) 만성정신질환자 대상의 치료환경을 그 환경적 특성에 따라 전통적인 외래치료환경, 개방적인 입원치료환경, 폐쇄적인 입원치료환경으로 분류하고, 각각의 치료환경에 거주하는 만성정신질환자의 주관적 및 객관적 삶의 질을 평가 비교함으로서 치료환경의 특성과 차이를 알아보고자 하였다. 방 법: 전통적인 외래치료환경 환자 85명, 개방병동 입원환자 67명, 폐쇄병동 입원환자 58명이었다. 이들에게 Lehman quality of life scale을 사용하여 반구조적 면담을 시행하여 삶의 질의 객관적 및 주관적 지표들의 지수를 측정하고 세 환경간 측정치를 비교하였다. 세 집단간의 차이를 분석하기 위해 ANOVA Test와 χ²검증을 사용하였다. 결 과: 환자들의 자율성과 다양한 정신사회재활 서비스가 제공되고 있는 개방병동 환자들의 전반적인 생활에 대한 만족도가 지역사회 및 폐쇄병동의 환자들에 비해 더 높았다. 지역사회에서 외래치료를 받는 환자들은 한달 쓰는 용돈이 많고 피해를 본 경험이 적었지만, 여가활동 및 사회적 접촉빈도가 입원환자에 비해 더 낮았고, 건강과 재정, 여가활동의 주관적 만족도도 더 낮았다. 입원치료중인 만성질환자들은 지역사회 환자들에 비해 여가활동 및 사회적 접촉빈도가 더 많았고, 월 평균 쓰는 비용이 더 적었지만 주관적 만족도는 오히려 더 높았다. 또한 이들은 최근 1년간 폭력 및 비폭력에 피해를 당한 경험이 더 많았으며, 건강에 관한 만족도는 더 높았다. 결 론: 치료환경의 특성에 따라 만성정신질환자가 보고하는 삶의 질에 차이를 보였으며, 개방병동에서 생활하고 있는 만성정신질환자들의 삶의 질이 가장 높았다. 향후 지역사회에 거주하고 있는 환자들의 삶의 질 향상을 위해서는 다양한 정신사회재활 서비스가 제공될 필요성이 있을 것으로 보았다. Objectives: This study aimed to figure out the characteristics and differences of therapeutic environment by classifying into closed-ward inpatient, open-ward inpatient and community residence out-patient environment and comparing objective and subjective quality of life of each group. Methods : The subjects consisted of 67 open-ward chronic inpatients, 58 closed -ward inpatients in the National Naju Mental Hospital and 85 outpatients living in Naju. We measured objective and subjective quality of life using semi-structural interview by Leman`s quality of life scale and compared the 3 groups. We used one-way ANOVA and chi-square test to analyze the differences of the 3 groups. Results: Open-ward inpatients who have autonomy and various community service program were more satisfied with their general life than the others. Community residence outpatients spent more money and less assaults experience but their leisure activities and social contact frequencies were lower than in the inpatients. Outpatients were less satisfied with their health, finances and leasure activities. Inpatients had made leisure activities and higher social contact frequency than outpatients. They were more satisfied with their finances despite of the spending less the money monthly than the outpatients. They experienced violence and damage more often for the past one year and were more satisfied with their health. Conclusions: The quality of life reported by chronic mental patients differed according to the characteristics of therapeutic environment. The life-quality of open-ward inpatients were the highest among the 3 groups. It is necessary to serve various community service program so that we can improve the life-quality of community residence outpatients.

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