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      • 백서의 복강내에 투여한 Mitomycin-C-Polyglycolic acid 제형이 장기에 미치는 영향에 관한 연구

        송규상,강대영,최정목,노승무,정경수,오정연,김진향,양준목,최선웅,이진호,조준식,민병무,김용백,김창식,박근성,김승영,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

        To evaluate the in-vivo effects of mitomycin-C-polyglycolic acid composite(MMC-PGA) the disk: shaped composite were implanted into the peritoneal cavity of the Sprague-Dawley rats. The pathologic changes were examined at various time points up to 12 weeks. Initially the soft tissue around the inserted disks showed capillary congestion at 3 days. Inflammatory infiltrates with foreign body giant cells appeared from the 2nd week and reached peak response at 6-8 weeks. These reaction diminished prominently at 12 weeks. No specific pathologic change was found in the liver, the kidneys, and the heart. The above results suggest that the MMC-PGA composite can serve as a new device for intraperitoneal chemotherapy of various types of cancers.

      • 치과기공사의 작업환경 개선 설비현황과 업무 스트레스 관련 연구

        정인호,신중규,이송권 慶山大學校 保健福祉硏究所 2003 保健福祉硏究 Vol.8 No.-

        The purpose of this study was to find out a scheme to reduce a job stress of dental technicians and to increase and operation efficiency with the improvement of working environment. The method of study was by the questionnaire-survey from dental technicians working in the dental clinics or the dental department of clinics or hospitals in DaeguㆍKyungbuk, for the period of Jul 1 - Aug 2, 2002. Here 246 ones answered relative faithfully among 300 questionnaires were used. The results of study were as follows; 1. In the stress degree of dental technicians, stress by work load, job conflict, and pay showed significant results in crown jobs(p<0.001), long-time workers(p<0.0001) and discontinuing workers(p<0002), and technicians(p<0.007), respectively. 2. From looking over facility for improvement of working environment conditions of dental technicians, it's found that most of illumination and noise protection facilities and a part of respiratory protection facilities are not installed for dental technicians satisfactorily. 3. In relationship between installation for work environment improvement and stress, technicians who worked in good environment condition had lower stress degree than workers with unsatisfied work enrironment in most of all characteristics. Especially the result showed that installation for respiratory system is very important for reduction of factors causing stresses.

      • KCI등재후보

        표피 종양에서 Epidermal Growth Factor Receptor의 발현 비교

        송준영,이규석,정재봉 啓明大學校 醫科大學 1994 계명의대학술지 Vol.13 No.4

        Epidermal growth factor(EGF) and transforming growth factor alpha(TGFα) are important keratinocyte mitogens. Their effect are mediated by a cell membrane receptor(EGFR), quantitive and qualitive abnormalities of which may be responsible for deranged keratinocyte proliferation and differentiation. We have therefore examined EGFR expression immunohistochemically in a variety of benign and malignant epithelial neoplasms using monoclonal antibodies to the extracellular and intracellular receptor domains, In benign tumor(seborrheic keratosis), there was an ordered pattern of EGFR expression. In malignant tumors(basal and squamous cell carcinoma), there was loss of membrane labelling and cytoplasmic accumulation of the receptor. In premalignant prolifertation(Bowen's disease), there was loss of membrane receptor with absent cytoplasmic EGFR. In slot-blot analysis, the levels of EGFR mRNA in sguamous cell carcinoma and basal cell carcinoma revealed 3 fold elevation when compared to normal skin. We suggest that dysregulation of the EGFR may be important in the development of cutaneous epithelial malignancies.

      • 황성 섬강 상류의 어류상

        송호복,권오길,전상호,김휘중,조규송 江原大學校 附設 環境硏究所 1996 環境硏究 Vol.13 No.-

        Fish fauna was investigated from June to November 1993 at the upper Sum river in Hoengsong. Form of stream was Aa and Aa-Bb, and pH, DO and BOD were 7.3~7.9, 8. 8~10.2mg/1 and 1.3~l. 5mg/1. The collected fishes were classified twenty nine species belonging to twenty two genera and seven family , of witch twelve species were endemic species of Korea. Dominant species was Zacco temmincki and subdominant species was Coreoleuciscus splendus. Zacco platypus, Microphgsogobio longidorsalis and Acheilognathus signifer were also numerous. Scarce species were Hemibarbus labeo, Coditis lutheri and the like. The species diversity index, dominance index and evenness index were 2.552, 0.384 and 0.758.

      • KCI등재

        박병천류 진도북춤 수행시 심폐기능 분석을 통한 운동강도와 에너지소비량의 평가

        조남규,송정은 韓國舞踊敎育學會 2001 韓國舞踊敎育學會誌 Vol.12 No.2

        The purpose of this study is to evaluate on the cardiopulmonary function of working capacity, work intensity and energy expenditure of jindobookchoom in college women who are majoring dance. The subject of this study were selected of 14 college women who are majoring Korean dance(average career 6.43years). Subject participated in 6min. of jindobookchoom and maxim exercise test to set maximal intensity. This study to measured portable gas analyzer for the cardiopulmonary function of working capacity, work intensity and energy expenditure at dance hall of H university. The following results concerning their work intensity and energy expenditure were obtained. 1.The subjects' average HR was 83.07±11.06 beats/min at the rest condition, and maximal HR recorded 186.36±10.07 beats/min, average maximal oxygen uptake per body weight was 45.61±5.32 ml/kg/min. at maximal exercise test. 2.The subject' height averaged 165.14±2.71 cm, body weight 52.50±2.47 kg, and body surface area was 1.56±0.23 3.The subjects' average HR was 160.06±28.71 beats/min, during performed Jindobookchoom and this value was 88.57 %HR max. 4.As to average energy expenditure, energy expenditure per body weight and total energy expenditure were 7.61±1.87kcl/min, 0.140±0.061 kcal/kg/min during performed Jindobookohoom 5.Correlation coefficients between the Cardiopulmonary Function and Energy Expenditure produces statistically significant(P<0.05-P<0.01) higher correlation among during Jindobookchoom Dancing According to results, Intensity and energy expenditure of Jindobookchoom reach the level to fencing(0.146 kcal/kg/min), field hocky(0.146 kcal/kg/min), basketball(0.138kcal/kg/min), 10kg loaded mountin climing(0.140 kcal/kg/min). As above, Intensity and energy expenditure of Jindobookchoom belong to the medium exercise, this is considered a desirable aerobic exercise. And it had sufficient working capacity as compared various activities.

      • KCI등재
      • KCI등재

        계승영구치가 선천적 결손된 유치의 치근 흡수

        이정은,이제호,최형준,김성오,송제선,손흥규,최병재 대한소아치과학회 2009 大韓小兒齒科學會誌 Vol.36 No.4

        유치의 정상적인 치근 흡수는 계승 영구치의 맹출 압력으로 단핵구 세포가 방출되어 파골세포로의 분화가 촉진되어 일어나며, 계승 영구치의 맹출 경로를 따라 유치의 치근이 흡수되어서 유치가 탈락하게 된다. 계승 영구치가 선천적으로 결손되었을 때에도 유치의 치근은 흡수될 수 있는데, 유치의 비정상적 치근흡수는 외상이나 염증, 교합압의 증가, 지지조직의 약화 등으로 발생할 수 있다. 치아의 선천적 결손은 인간에서 가장 흔한 발육이상이며, 영구치가 결손되었을 때 유치는 만기 잔존할 수 있다. 영구치의 선천적 결손은 전신질환이 있는 경우뿐만 아니라 국소적 원인이나 인류 진화에 따른 영향 등에 의해서도 발생한다. 이 증례들은 계승 영구치가 선천적으로 결손된 어린이에서 유치의 치근이 비정상적으로 흡수된 경우로 계승 영구치가 결손 된 유전치와 유견치, 유구치의 치근이 1/2 ~ 3/4정도까지 흡수 되었으며 흡수 부위는 불규칙적인 형태를 보였다. 원인으로는 흡수에 감수성이 높은 유치의 치주인대, 그리고 성장에 따라 증가되는 저작근육과 저작력, 혼합치열기에 유발되는 비정상적 교합 등을 생각할 수 있다. 계승 영구치가 결손된 유치가 비정상적인 치근 흡수를 보이는 경우에 유치는 유지될 수도 있지만, 여러 요인에 의하여 탈락될 경우에는 공간을 유지 할 것인지 판단해야 하며, 향후 보철치료나 교정치료를 요하므로 장기적인 치료계획을 수립해야 한다. Root resorption of primary teeth usually occurs as the succeeding permanent teeth erupt, which induces differentiation of the hemopoietic cells into osteoclasts. Their root resorption pattern reflects the eruption path of the succeeding permanent teeth, and eventually the primary teeth shed as their succeeding permanent teeth erupt. Even when a permanent tooth germ is congenitally missing, root resorption of the corresponding primary tooth may still occur due to various factors, such as inflammation, traumatic occlusal force, and weakness of periodontium etc. Such congenital missing of permanent teeth is a commonly observed phenomenon in human be ing, and it often accompanies delayed retention of primary teeth. The etiologic factors for congenital missing in elude not only systemic diseases, but also local factors and human evolution process. In the radiographs of the cases in this report, the primary teeth without succeeding permanent teeth show pathologic root resorption. Root resorption progressed about 1/2~3/4 of the roots, and the surfaces of the resorption area were irregular. Considering high susceptibility of the periodontal ligament of primary teeth to root resorption, pathologic root resorption of primary teeth with delayed retention can be explained by the increased masticatory muscle force and abnormal occlusion developed during the mixed dentition. When the primary teeth without succeeding permanent teeth are lost, decision for space maintenance is required and long-term treatment plan for further prosthetic or orthodontic treatment should be establsihed.

      • 제조에 對한 文獻的 考察

        안태규,최병렬,송기철,이용연,유화승,서상훈,최우진,조정효,이연월,손창규,조종관 대전대학교 한방병원 2001 惠和醫學 Vol.10 No.1

        In the literatual study on Holotrichia, the results were obtained as follows ; 1. Holotrichia is larva of Holotrichia diomphalia Bates etc. powder or liquor of Holotrichia is used medically. 2. Appearance of Holotrichia is shape of kidney, yellowish color. 3. The oriental characters of Holotrichia is warm, toxicant, salty. 4. The significant efficancy of Holotrichia is breaking the stagnant blood. 5. Holotrichia can be applied to the diseases related to thrombosis, and recover the demage of liver. 6. Holotrichia avails Liver diseases such as Hepatitis, Liver cirrhosis, Hepatosplenomegaly, Hepatoma etc.

      • 부유대역 용융응고법으로 제조된 YBa_2Cu_3O_x 산화물초전도체의 미세구조와 전기적 특성

        노태형,송정환,장규철,한이섭,김소정,구본급,김호기 대전산업대학교 반도체기술연구소 2000 半導體技術硏究所報 Vol.2 No.-

        The YBa_2Cu_3O_x-20 wt% Y_2BaCuO_5 composition designed in YBCO system was synthesized by solid state reaction method. The optimum condition of hot zone temperature and growth rate in floating-zone melt were 1080 ℃ and 2.5 mm/hour, respectively. In samples growth as these condition, the low angel boundaries in grain direction and small amount of amorphous phase known as decreasing characteristics of superconducting materials between grain boundaries in microstructure are investigated by polarized light microscopy on the whole. The critical current density(Jc) at 77k of sample using powder fabricated with no CeO_2 and doped 5 wt%CeO_2 were 8,000 A/㎠(Jc : 561A) and 12,000 A/㎠(Jc: 826A) at 0 T by direct current transport method, respectively.

      • 지능형 원격 네트워크 온실

        문병현,송주열,이현성,손경규,엄태환,김정우,김아름 대구대학교 정보통신연구소 2004 情報通信硏究 Vol.3 No.2

        The system designed in this paper, can mark the interior state of greenhouse using sensors of temperature, humidity and illumination on greenhouse interior by greenhouse system for farm village area's agriculture automation. And, the real time monitor is possible real time monitoring by camera. Also, system that can supply water using spring cooler system and humidifier. The proposed system can sustain a designed environment of the greenhouse through rentilation fan, fluorescent light and roof door control. TCP/IP is used for the remote control of state the sensors in the client program. 본 논문에서 설계된 시스템은 농촌 지역의 농업 자동화를 위한 온실 시스템으로 온실 내부에 온도, 습도, 조도 센서를 이용한 온실 내부의 상태를 표시할 수 있으며 카메라를 이용하여 실시간 관측이 가능하다. 또한 본 시스템은 지붕 개폐, 스프링 쿨러와 가습기를 이용한 수분 공급, 환풍기, 형광등 등을 통하여 온실 내부의 환경을 유지시킬 수 있다. 모든 센서를 이용한 상태와 온실 제어를 TCP/IP를 이용한 클라이언트 프로그램에서 원격으로 관리할 수 있다.

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