Removal of C.I. Basic Blue 41 from aqueous solution by supercritical water oxidation in continuous-flow reactor

Onur O. Sogut,Mesut Akgun 한국공업화학회 2009 Journal of Industrial and Engineering Chemistry Vol.15 No.6

Oxidation of aqueous solution of C.I. Basic Blue 41 (BB41), which is model azo dye pollutants, was studied in a continuous-flow reactor that was operated between 400 and 650 ℃ at a fixed pressure of 25 MPa. The total organic carbon (TOC) concentration of BB41 was in the range of 30.60 and 152.97 mmol/L in the feed stock solution. Hydrogen peroxide (H2O2) was used as an oxygen source and the oxidant concentrations were between 73.53 and 489.64 mmol/L in the feed stock solution. The results demonstrated that supercritical water oxidation (SCWO) process decreases the TOC up to 99.87% in very short reaction times (at residence times of 9–19 s). According to the wastewater and oxidant concentrations, the global rate expression was regressed from the complete set of data for each dye solution. As a result of regression analysis, the reaction rate expression for the oxidation of BB41 was determined with the activation energy of 18.88 (±0.9) kJ/mol and the pre-exponential factor of 2.8 (±0.5) mmol-0.16 L0.16 s-1; and the reaction orders for BB41 (based on TOC) and the oxidant were 0.84 (±0.03) and 0.32 (±0.05) in a 95% confidence level.

Long-term Effects of Uncomplicated Traumatic Hyphema on Corneal and Lenticular Clarity

Ali Keles(Ali Keles ),Pinar Kosekahya(Pinar Kosekahya ),Furkan Emre Sogut(Furkan Emre Sogut ),Mustafa Salih Karatepe(Mustafa Salih Karatepe ) 대한안과학회 2022 Korean Journal of Ophthalmology Vol.36 No.6

Purpose: To evaluate the long-term effects of uncomplicated traumatic hyphema on endothelial morphology, anterior segment structure, and corneal and lenticular densitometry Methods: In this retrospective comparative study, eyes with a history of uncomplicated traumatic hyphema were compared with the healthy contralateral unaffected eyes. The corneal endothelial cell properties were captured using specular microscopy. Anterior segment analysis, corneal densitometry (12-mm corneal diameter), and lens densitometry measurements were performed using the Pentacam imaging system. Results: Measurements were obtained at a mean follow-up of 49.5 ± 15.8 months after injury. The average endothelial cell density was significantly lower in the study group than in the control group (2,506.6 ± 294.0 cells/mm² vs. 2,665.7 ± 195.0 cells/mm², p = 0.020). There was no difference between the groups in respect of polymegathism and pleomorphism (p = 0.061 and p = 0.558, respectively). All the investigated corneal tomographic and angle parameters were similar in both groups (all p > 0.05). The corneal densitometry values in all concentric zones and layers showed no statistically significant difference between the groups (p > 0.05 for all). The lens zone 1 densitometry value was significantly higher in the study group than in the control group (9.6% ± 1.1% vs. 8.9% ± 1.2%, p = 0.031). No difference was observed in zone 2 and 3 (p = 0.170 and p = 0.322, respectively). The degree of hyphema was not correlated with endothelial cell and lenticular clarity loss (p = 0.087 and p = 0.294, respectively). Conclusions: Even if traumatic hyphema is not complicated, long-term outcomes indicate endothelial cell loss and increased lenticular density.

Calcium and Magnesium Contents in Three Hypericum L. Species from Turkey

Gozde Elgin Cebe,Ozlem Sogut 한국식품영양과학회 2018 Journal of medicinal food Vol.21 No.8

Hypericum L. (Hypericaceae), which has 400 species in the world and 96 species in Turkey, has grown in Europe, Asia, North Africa, and America. Hypericum species have antidepressant, analgesic, spazmolytic, anti-inflammatory, antiviral, and wound healing effects. The purpose of this study was to analyze the magnesium (Mg) and calcium (Ca) contents of three Hypericum species (Hypericum perforatum L., Hypericum triquetrifolium Turra, and Hypericum empetrifolium Willd.) collected from the western part of Turkey. Analyses were done by atomic absorption spectrometer using convenient conditions. Mg and Ca concentrations were determined in three Hypericum species. Mg levels were determined as 1.053 ± 0.09, 0.792 ± 0.06, and 0.798 ± 0.17 mg.g−1 and Ca levels were determined as 0.573 ± 0.19, 0.433 ± 0.06, and 0.329 ± 0.005 mg.g−1 in H. perforatum L., H. triquetrifolium Turra, and H. empetrifolium Willd., respectively. The sedative effect of the drug is compensated with the metal concentration observed from the analysis, which shows that high Mg levels overlap with the sedative effect of the drug.

Role of Adipokines and Hormones of Obesity in Childhood Asthma

Hasan Yuksel,Ayhan Sogut,Ozge Yilmaz,Ece Onur,Gonul Dinc 대한천식알레르기학회 2012 Allergy, Asthma & Immunology Research Vol.4 No.2

Purpose: The aim of this study was to evaluate serum levels of leptin, ghrelin, and adiponectin in obese and non-obese children with asthma and in healthy non-asthmatic children, and analyze their relationships with clinical outcomes. Methods: This study enrolled 40 obese and 51 non-obese children with asthma and 20 healthy children. Body mass index and serum leptin, ghrelin, and adiponectin levels were determined in all children. Asthma symptom scores and lung function test results were recorded for subjects with asthma. Results: Serum leptin levels (11.8±7.9, 5.3±6.8, and 2.1±2.4 ng/mL in the obese asthmatic, non-obese asthmatic, and control groups, respectively) and adiponectin levels (12,586.2±3,724.1; 18,089.3±6,452.3; and 20,297.5±3,680.7 ng/mL, respectively) differed significantly among the groups (P<0.001 for all). Mean ghrelin levels were 196.1±96.8and 311.9±352.8 pg/mL in the obese and non-obese asthmatic groups, respectively, and 348.8±146.4 pg/mL in the control group (P=0.001). The asthma symptom score was significantly higher in the obese children with asthma than in the non-obese children with asthma (P<0.001). Leptin and adiponectin levels were correlated with the asthma symptom score in non-obese children with asthma (r=0.34 and r=-0.62, respectively). Conclusions:Obesity leads to more severe asthma symptoms in children. Moreover, leptin, adiponectin, and ghrelin may play important roles in the inflammatory pathogenesis of asthma and obesity co-morbidity.

Effects of Beak Trimming, Stocking Density and Sex on Carcass Yield, Carcass Components, Plasma Glucose and Triglyceride Levels in Large White Turkeys

Sengul, Turgay,Inci, Hakan,Sengul, Ahmet Y.,Sogut, Bunyamin,Kiraz, Selahattin Korean Society for Food Science of Animal Resource 2015 한국축산식품학회지 Vol.35 No.6

This study was conducted to determine the effects of beak trimming, stocking density (D) and sex (S) on live weight (LW), carcass yield and its component, and plasma glucose (PG) and triglyceride levels in Large White turkeys. To accomplish this aims, totally 288 d old large white turkey chicks (144 in each sex) were used. Beaks of 77 male and female poults were trimmed when 8 d old with an electrical beak trimmer. The birds were fed by commercial turkey rasion. Experiment was designed as 2 × 2 × 2 factorial arrangement with 3 replications in each group. Beak trimming and stocking density did not affect live weight, carcass composition and its components. The higher LW and carcass weight observed in trimmed groups. As expected, male birds are heavier than female, and carcass percentage (CP) would be adverse. However, in this study, CP of male was higher in trimmed, in 0.25 m²/bird. (D) × sex (S) interaction had an effect on both CP and thigh weights (p<0.05). Significantly D × S was observed in LW, CP and PG. The weight of carcass and its some components were higher in male. S × D interaction had an effect on plasma glucose level (p<0.05). Triglyceride level was affected (p<0.05) by sex. Significant relationships were found between percentage of thighs (r=0.447, p<0.01) and percentage of breast (r=0.400, p<0.01). According to this study, it can be said that trimming is useful with density of 0.25 m²/bird in turkey fattening.

Evaluation of Atherosclerotic Risk by Oxidative Contributors in Alcohol Use Disorder

Almila Senat,Esra Kabadayi-Sahin,Ibrahim Sogut,Tomris Duymaz,Ozcan Erel 대한정신약물학회 2023 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.21 No.3

Objective: Alcohol Use Disorder (AUD) is a condition described as the inability to control or stop alcohol consumption. The patients with AUD have an increased risk of developing atherosclerosis-related diseases. The present study aimed to evaluate oxidative contributors of atherosclerotic risk factors in patients with AUD. Methods: The male subjects diagnosed with AUD (n = 45) and the male subjects as control (n = 35) were enrolled in this study. All participants were undergone psychiatric evaluation and sociodemographic tests. Also, serum oxidative contributors of atherosclerosis including myeloperoxidase (MPO), ferroxidase, catalase (CAT), and lipid hydroperoxides (LOOH) were measured. Additionally, serum lipid profile tests and atherogenic indicators including atherogenic index of plasma (AIP) and non-high-density lipoprotein (HDL) cholesterol were also analyzed. Results: The AUD subject had significantly elevated MPO activity and LOOH levels with decreased antioxidant capacity. AIP and non-HDL cholesterol levels, the atherogenic indicators, were also higher in AUD group compared to the control group. We found the MPO activity and LOOH levels were positively correlated with AIP, non-HDL cholesterol levels, and amount of alcohol consumption. Additionally, CAT activity was negatively correlated with duration of alcohol consumption. Conclusion: Our results revealed that MPO and LOOH levels were elevated by severe alcohol intake and the atherogenic indicators, AIP and non-HDL cholesterol, were significantly correlated alcohol induced elevated oxidative risk factors. Therefore, it can be suggested that MPO activity and LOOH levels may be useful to determine jeopardy of atherosclerotic and the therapeutic interventions that reduce oxidative load could be taken into account to prevent atherosclerotic diseases before clinical manifestation.

Evaluation of Genetic Analysis with Autosomal Recessive Bestrophinopathy

Ali Mert Kocer,Mehmet Yasin Teke,Furkan Emre Sogut 한국망막학회 2019 Journal of Retina Vol.4 No.2

Purpose: We aimed to report a patient with autosomal recessive bestrophinopathy (ARB) who have novel compound heterozygous mutations in BEST1. Case summary: A 35-year old male patient who had no history of known trauma and disease was admitted to our hospital with bilateral visual disturbance since his childhood. Dilated fundus examination revealed widespread yellow-white subretinal accumulation and white scar formation on both posterior poles. Hyperfluorescent foci were observed along the vessel arcades in fundus autofluorescence imaging. Optical coherence tomography showed serous subretinal fluid under the bilateral macula. Arden rate was found to be 1.32 for right eye and 1.28 for left eye in the electrooculography examination. Bestrophinopathy was considered in the patient and a genetic examination test was performed for BEST1 gene. The whole gene sequence analysis test (Miseq-Illumina) performed on the BEST1 gene of the patient resulted in c.604C>T (p.Arg202Trp) (pR202W) /c.1013G>A (p.Trp338 *) (p.W338*) compound heterozygous mutation. Conclusions: ARB is a rare disease and usually associated with consanguineous marriage, the disease may also occur with different mutations of both spouses. For this reason, it is important that ophthalmologists consider the possibility of best retinopathy even in the absence of a consanguineous history.

Effects of Beak Trimming, Stocking Density and Sex on Carcass Yield, Carcass Components, Plasma Glucose and Triglyceride Levels in Large White Turkeys

Turgay Sengul,Hakan Inci,Ahmet Y. Sengul,Bunyamin Sogut,Selahattin Kiraz 한국축산식품학회 2015 한국축산식품학회지 Vol.35 No.6

This study was conducted to determine the effects of beak trimming, stocking density (D) and sex (S) on live weight (LW), carcass yield and its component, and plasma glucose (PG) and triglyceride levels in Large White turkeys. To accomplish this aims, totally 288 d old large white turkey chicks (144 in each sex) were used. Beaks of 77 male and female poults were trimmed when 8 d old with an electrical beak trimmer. The birds were fed by commercial turkey rasion. Experiment was designed as 2 × 2 × 2 factorial arrangement with 3 replications in each group. Beak trimming and stocking density did not affect live weight, carcass composition and its components. The higher LW and carcass weight observed in trimmed groups. As expected, male birds are heavier than female, and carcass percentage (CP) would be adverse. However, in this study, CP of male was higher in trimmed, in 0.25 m2 /bird. (D) × sex (S) interaction had an effect on both CP and thigh weights (p<0.05). Significantly D × S was observed in LW, CP and PG. The weight of carcass and its some components were higher in male. S × D interaction had an effect on plasma glucose level (p<0.05). Triglyceride level was affected (p<0.05) by sex. Significant relationships were found between percentage of thighs (r=0.447, p<0.01) and percentage of breast (r=0.400, p<0.01). According to this study, it can be said that trimming is useful with density of 0.25 m2 /bird in turkey fattening.

Influence of trapezoidal and sinusoidal corrugation on the flexural capacity of optimally designed thin-walled beams

Ferhat Erdal,Osman Tunca,Harun Taylan,Ramazan Ozcelik,Huseyin Sogut 국제구조공학회 2022 Structural Engineering and Mechanics, An Int'l Jou Vol.84 No.1

Major engineering requirements and technological developments in the steel construction industry are discussed to support a new innovative system, namely corrugated web beams, for future structural projections. These new-generation steel beams, fabricated as welded plate girders with corrugated webs, are designed to combine large spans with very low weight. In the present study, the flexural capacity of optimally designed trapezoidal and sinusoidal corrugated web beams was aimed at. For this purpose, the new metaheuristic methods, specifically hunting search and firefly algorithms, were used for the minimum weight design of both beams according to the rules of Eurocode EN 1193 15 and DASt-Ri 015. In addition, the strengthening effects of the corrugation geometry at the web posts on the load capacity of fabricated steel beams were tested in a reaction frame. The experimental tests displayed that the lateral capacity of trapezoidal web beams is more durable under flexural loads compared to sinusoidal web beams. These thin-walled beams were also simulated using a 3-D finite element model with plane strain to validate test results and describe the effectiveness of the ABAQUS software.

Assessment of MMP-1, MMP-8 and TIMP-2 in experimental periodontitis treated with kaempferol

Umut Balli,Burcu Ozkan Cetinkaya,Gonca Cayir Keles,Zeynep Pinar Keles,Sevki Guler,Mehtap Unlu Sogut,Zuleyha Erisgin 대한치주과학회 2016 Journal of Periodontal & Implant Science Vol.46 No.2

Purpose: The objective of this study was to investigate the effect of a dietary flavonoid, kaempferol, which has been shown to possess antiallergic, anti-inflammatory, anticarcinogenic, and antioxidant activities on the periodontium by histomorphometric analysis and on gingival tissue matrix metalloproteinase-1 (MMP-1), MMP-8, and tissue inhibitor of metalloproteinase-2 (TIMP-2) by biochemical analysis of rats after experimental periodontitis induction. Methods: Sixty Wistar rats were randomly divided into six groups of ten rats each, and silk ligatures were placed around the cervical area of the mandibular first molars for 15 days, except in the healthy control rats. In the experimental periodontitis groups, systemic kaempferol (10 mg/kg/2d) and saline were administered by oral gavage at two different periods (with and without the presence of dental biofilm) to all rats except for the ten non-medicated rats. Alveolar bone area, alveolar bone level, and attachment level were determined by histomorphometric analysis, and gingival tissue levels of MMP-1, MMP-8, and TIMP-2 were detected by biochemical analysis. Results: Significantly greater bone area and significantly less alveolar bone and attachment loss were observed in the kaempferol application groups compared to the control groups (P<0.05). In addition, gingival tissue MMP-1 and -8 levels were significantly lower in the kaempferol application groups compared to the control groups and the periodontitis group (P<0.001). There were no statistically significant differences in TIMP-2 levels between the kaempferol and saline application groups (P>0.05). Conclusions: Kaempferol application may be useful in decreasing alveolar bone resorption,attachment loss, and MMP-1 and -8 production in experimental periodontitis.