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      • KCI등재

        Predictive Value of the TRACK Questionnaire as a Measure of Asthma Control in Preschool Aged Children

        Ozge Yilmaz,Ahmet Turkeli,Sebnem Sahin,Hasan Yuksel 대한천식알레르기학회 2014 Allergy, Asthma & Immunology Research Vol.6 No.4

        Assessment of asthma control in preschool children is important for therapeutic decisions. Aim of this study was to evaluate the predictive value ofTRACK questionnaire scores for subsequent clinical parameters and to investigate the validity and reliability of the Turkish version of the TRACKquestionnaire. We enrolled 100 children with asthma aged 4 years or younger in this cohort study. We recorded sociodemographic characteristicsand clinical severity parameters. A pediatric allergist filled in the asthma severity scale and the caregiver of the child filled in the TRACK questionnaire. We called in the children again at the end of one month and recorded the same parameters and administered TRACK again. Uncontrolled asthmawas defined as a TRACK score below 80. According to the TRACK score, 65% of the children had controlled asthma initially while at the end ofthe study 64.1% had controlled asthma. At the beginning of the study, all clinical parameters were worse in children with uncontrolled asthma accordingto TRACK score. Similarly, other objective clinical parameters during the following one month period were worse in children with initial uncontrolledasthma. Cronbach’s alpha score for the TRACK questionnaire was 0.84. Turkish TRACK questionnaire is a valid and reliable tool that is predictiveof short term asthma prognosis.

      • KCI등재

        Clinical, virological, imaging and pathological findings in SARS CoV-2 antibody positive cat

        Kursat Ozer,Aysun Yilmaz,Mariano Carossino,Gulay Yuzbasioglu Ozturk,Ozge Erdogan Bamac,Hasan E. Tali,Egemen Mahzunlar,Utku Y. Cizmecigil,Ozge Aydin,Hamid B. Tali,Semaha G. Yilmaz,Zihni Mutlu,Ayse Ilgı 대한수의학회 2022 Journal of Veterinary Science Vol.23 No.4

        This paper reports a presumptive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in a cat. A cat with respiratory disease living with three individuals with coronavirus disease 2019 showed bilateral ground-glass opacities in the lung on X-ray and computed tomography. The clinical swabs were negative for SARS-CoV-2 RNA, but the serum was positive for SARS-CoV-2 antibodies. Interstitial pneumonia and prominent type 2 pneumocyte hyperplasia were noted on histopathology. Respiratory tissues were negative for SARS-CoV-2 RNA or antigen, but the cat was positive for feline parvovirus DNA. In conclusion, the respiratory disease and associated pathology in this cat could have been due to exposure to SARS-CoV-2.

      • KCI등재

        On the sequences related to Fibonacci and Lucas numbers

        Nihal Yilmaz ÄOzgÄur 대한수학회 2005 대한수학회지 Vol.42 No.1

        In this paper, we obtain some properties of the se-quences Uq n and Vqn introduced in [6]. We ¯nd polynomial repre-sentations and formulas of them. For q = 5, U5n is the Fibonacci sequence Fn and V5n is the Lucas sequence Ln.

      • KCI등재

        Factors Affecting Food Allergy-Related Quality of Life From Parents’ Perception in Turkish Children

        Ebru Arik Yilmaz,Ozlem Cavkaytar,Betul Buyuktiryaki,Ozge Soyer,Umit M. Sahiner,Bulent E Sekerel,Audrey DunnGalvin,Erdem Karabulut,Cansin Sackesen 대한천식알레르기학회 2018 Allergy, Asthma & Immunology Research Vol.10 No.4

        Purpose: Food allergy (FA) affects the daily lives of children and parents in varying degrees. The Food Allergy Quality of Life Questionnaire-Parent Form (FAQLQ-PF) is a valid and reliable instrument to assess the quality of life (QoL) of children from parents’ perception. The aim of this study was to validate and determine the reliability of the Turkish FAQLQ-PF and to assess QoL in food-allergic children. Methods: Children aged between 0 and 12 years and diagnosed with immunoglobulin E (IgE)-mediated FA for at least 1 month were enrolled. The English FAQLQ-PF was translated into Turkish according to the World Health Organization guidelines. The Food Allergy Independent Measure and the Turkish Child Health Questionnaire- Parent Form 50 were used for construct validity. Results: One hundred and fifty-seven patients participated. The median age of patients and FA duration were 2.4 years (1.2-5.2 years, interquartile-ranges) and 2 years (0.8-5.1), respectively. Ninety-six (61.1%) patients had anaphylaxis. The Cronbach’s alpha coefficient and intra-class correlation coefficient for test-retest reliability was good for all age groups of children (< 4, 4-6, and 7-12 years). Patients with either asthma or anaphylaxis had worse scores than others. Total scores of FAQLQ-PF tended to increase with age. Patients aged 7-12 had the highest total scores among all patients (2.2±0.1, 3.0±0.2, and 3.3±0.3 for < 4, 4-6, and 7-12 years, respectively, P < 0.001, P for trend < 0.001). Other factors causing the poor QoL were cow’s milk allergy, sibling allergy, mother’s age over 30 years, mother’s high education level and lower number of persons in household. Conclusions: The Turkish FAQLQ-PF is a valid and reliable scale. FA-related QoL was significantly worse with age. Coexistent asthma, anaphylaxis regardless of its severity, cow’s milk allergy, sibling allergy and the older and educated mothers seem to poorly affect QoL.

      • KCI등재후보

        Role of Adipokines and Hormones of Obesity in Childhood Asthma

        Hasan Yuksel,Ayhan Sogut,Ozge Yilmaz,Ece Onur,Gonul Dinc 대한천식알레르기학회 2012 Allergy, Asthma & Immunology Research Vol.4 No.2

        Purpose: The aim of this study was to evaluate serum levels of leptin, ghrelin, and adiponectin in obese and non-obese children with asthma and in healthy non-asthmatic children, and analyze their relationships with clinical outcomes. Methods: This study enrolled 40 obese and 51 non-obese children with asthma and 20 healthy children. Body mass index and serum leptin, ghrelin, and adiponectin levels were determined in all children. Asthma symptom scores and lung function test results were recorded for subjects with asthma. Results: Serum leptin levels (11.8±7.9, 5.3±6.8, and 2.1±2.4 ng/mL in the obese asthmatic, non-obese asthmatic, and control groups, respectively) and adiponectin levels (12,586.2±3,724.1; 18,089.3±6,452.3; and 20,297.5±3,680.7 ng/mL, respectively) differed significantly among the groups (P<0.001 for all). Mean ghrelin levels were 196.1±96.8and 311.9±352.8 pg/mL in the obese and non-obese asthmatic groups, respectively, and 348.8±146.4 pg/mL in the control group (P=0.001). The asthma symptom score was significantly higher in the obese children with asthma than in the non-obese children with asthma (P<0.001). Leptin and adiponectin levels were correlated with the asthma symptom score in non-obese children with asthma (r=0.34 and r=-0.62, respectively). Conclusions:Obesity leads to more severe asthma symptoms in children. Moreover, leptin, adiponectin, and ghrelin may play important roles in the inflammatory pathogenesis of asthma and obesity co-morbidity.

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