IMT-2000용 수신단 One-chip MMIC의 설계 및 제작

신상문,권태운,최재하 울산대학교 2002 공학연구논문집 Vol.33 No.1

본 논문은 IMT-2000용 수신단 One-chip MMIC의 설계 및 제작에 관한 것이다. LNA, 이중 평형 믹서, LO 발룬, RF 발룬, 그리고 IF 증폭기를 하나의 칩에 집적시켰다. 새롭게 제안된 바이어스 회로는 공정상의 변화와 온도의 변화 등의 원인에 의한 문턱전압의 변화를 보상할 수 있다. 제작된 칩의 측정 결과는 모의실험으로 얻은 결과와 일치하지 않는다. LNA는 변환이득이 평탄하게 동작하지 않을 뿐만 아니라 발진현상도 나타났다. 문제에 대한 분석을 통해 원인을 찾았으며, 이 결과는 향후 연구에 사용하려고 한다. 믹서의 변환손실은 -14㏈, IP3는 4㏈m, 포트간 격리도는 25㏈ 이상인 특성을 나타낸다. 설계된 칩은 ETRI MESFET 0.5 ㎛공정으로 제작하였으며 칩 사이즈는 1.4㎜×1.4㎜이다 This is paper describes a design and fabrication of a one-chip receiver MMIC for IMT-2000. The LNA, double balanced mixer, LO balun, RF balun, IF amplifier and a bias circuit are integrated a chip. Each balun operates active and composed of MESFETs. The new applied bias circuit is able to compensate the variation of the threshold voltage caused by the process variation, temperature changes, and etc. The measured response of the fabricated chip doesn't correspond with the simulated performance, the LNA is not only the conversion gain doesn't operates flatly, but also even the oscillation presented. By the study of the cause about the problem, the factor was found. And the result will be deal with further study. The mixer achieves the conversion losses of -14㏈, IP3 of 4㏈m, and port to port isolation over 25㏈. The designed chip is fabricated by the ETRI MESFET 0.5㎛ process. The chip size is 1.4m×1.4m.

근관감염균에 대한 polyphosphate의 항균효과

신정희,박상진,최기운 大韓齒科保存學會 2003 Restorative Dentistry & Endodontics Vol.28 No.6

This study was performed to observe the antibacterial effect of polyphosphate (polyP) with various chain lengths (P3~P75) on virulent. invasive strains of P. gingivalis A7A1 28 and W50, and multidrug resistant E. faecalis ATCC29212. P. gingivalis strains were grown in brain heart infusion broth (BHI) containing hemin and vitamin K with or without polyP. PolyP was added at the very beginning of the culture or during the exponential growth phase of the culture. Inhibition of the growth of P. gingivalis was determined by measuring the absorbancy at 540nm of the grown cells. Viable cell counts of the culture and release of intracellular nucleotide from P. gingivalis were measured. E. faecalis was grown in plain BHI with antibiotics alone or in combination with polyP(calgon: 0.1-1.0%) and the bacterial absorbancy was measured. The overall results suggest that polyP has a strong antibacterial effect on the growth of the virulent strains of P. gingivalis and the antibacterial activity of polyP seems largely bactericidal. accompanying bacteriolysis in which chelation phenomenon is not involved. Although polyP does not exert antibacterial activity against E. faecalis, it appears to increase antibacterial effect of erythromycin and tetracycline on the bacterium. Therefore, polyP alone or in combination with antibiotics may be developed as a candidate for the agent controlling oral infections including endodontic infection.

Cubic B-Spline을 이용한 측면 얼굴의 인식 방법

신성효,이인순,김상운 명지대학교 공학기술연구소 1994 공학기술연구소 논문집 Vol.9 No.-

Profile contours can be a useful tool for facial recognition problems, and many efforts have been made in this field. These researches mainly concentrated on the feature extraction by making use of the positional information of a nose tip. Most importantly, incorrect extraction of the positional information of the nose tip degrades the overall performance of the facial recognition system. For instance, when facial images are tippd, the possibility of erroneous extration of nose tip position is high. However, endeavors to account for the tipped images. such as gathering and analyzing facial images from various viewpoints, have never been made as yet. This paper provides a method for the facial recognition by extracting multiple control points. Given a profile image, we extract the profile contour through binary processing. Since the contour is a space curve, curvature can readily be obtained at any point lying on the curve. By examining the signs at eight curvature extrimities, facial direction of the given profile image can be determined, and this information is used to derive the direction of front image. Finally, a cubic-polynomial curve which minimize the least square error at extremities is calculated and used to get control points of the corresponding cubic B-Spline. Thirteen features from the control points show the recognition rate of approximately 90 percents.

한국재래흑염소에서 발정 및 과배란 유도와 외래유전자 주입에 적합한 1세포기 수정란의 채취

신상태,이두환,김명철,이운규,이철상,한용만,이경광 충남대학교 수의과대학 동물의과학연구소 1998 動物醫科學硏究誌 Vol.6 No.-

Three different treatments for induction of estrus in Korean native black goats were compared: follicle stimulating hormone(FSH, FSH-p^TM), FSH combined with MAP(intravaginal impregnated sponges, Veramix^ⓡ, containing 60 ㎎ medroxy progesterone acetate for 14 days), and FSH combined with progesterone(Ovaron^ⓡ, 10 ㎎ IM for 10 days) and PGF_2α(Lutalyse^ⓡ, 3 ㎎ IM at first FSH injection). FSH for inducing estrus and superovulation was given a total 20 ㎎ intramuscularilly in decreasing dosage injections twice daily over 4 days. The MAPs were withdrawn at the 3rd day of FSH injection. Estrus observations were conducted every 6 hours from last FSH injection for 24 hours by placing the does with fertile male goats. Estrus and superovulation were more successfully induced with treatment of MAP + FSH than other treatments(FSH only, or progesterone + PGF_2α + FSH) (estrus induction; 100 vs 42.8 and 71.4%, ovulation points; 11.4 vs 5.4 and 4.4, respectively). The effect of gonadotropin releasing hormone(GnRH) on the ovulation rate was also examined. However, no difference was observed for inducing ovulation with treatment or dosage(100 ㎍ 200 ㎍) of GnRH. Low midline laparotomies were performed, and then ovarian responses (ovulations and follicular development) were examined by exteriorization of the reproductive tracts. Ova were recovered from oviducts by retrograde flushing 60-146 hours after MAP removal, and were classified the developmental stages. Overall 66.1% (236/357) of recovery rate was obtained from 30 superovulated does. The optimal recovery time of microinjectable 1-cell zygotes was approximately 72-76 hours after MAP removal.

Metallo-β-lactamase 생성 Pseudomonas aeruginosa 및 포도당 비발효그람음성간균의 검출방법에 관한 연구

신경섭,김원식,손재철,홍승복,최재운,형성민 충북대학교 의과대학 충북대학교 의학연구소 2003 忠北醫大學術誌 Vol.13 No.2

연구목적: Metallo-β-lactamse (MBL)는 carbepenem를 포함하는 대부분의 β-lactam 항균제를 가수분해할 수 있으므로 MBL 생성균의 확산은 이들 균에 의한 감염의 치료에 큰 문제를 야기할 수 있다. 따라서 MBL 생성균에 의한 감염의 확산을 막기 위해 이들 균의 조기 검출이 필요하다. 저자들은 MBL 생성균을 검출할 수 있는 세 가지 방법을 PCR 방법과 비교하여 보았다. 재료 및 방법: Imipenem의 MIC가 8 μg/mL 이상인 50개의 포도당 비발효 그람음성 간균을 대상으로 EDTA-double disk synergy test (EDTA-DDS), Etest MBL, Hodge 변법을 시행하였으며 대조 검사로 IMP-1, VIM-1, VIM-2에 대한 PCR을 시행하였다. 결과: 총 50 균주 중 MBL 생성균은 Pseudomonas aeruginosa 1 균주, Alcaligenens xylosxidans 7 균주 등 8 균주(16%)가 검출되었다. 이들 균주는 모두 VIM-2 형이었으며, EDTA-DDS, Etest MBL은 PCR 방법과 100% 일치하였다. Hodge 변법은 8 MBL 생성균주 중 2 균주를 검출하지 못했다. 결론: 50 균주 중 8 균주가 MBL 생성균이었고 모두 VIM-2 형이었다. Etest MBL은 가격이 비싸 검사실에서는 EDTA-DDS가 적당할 것으로 사료된다. Purpose: Because metallo-β-lactamase (MBL) has activity to hydrolysls against most β-lactam drugs, dissemination of MBL producing bacteria may cause problems of treatment of infection by their microorganisms. Early detection or screening for MBLs will contribute to prevent further spread of resistance. Authors compared three MBL detection methods with PCR for MBLs. Materials and Methods: For 50 isolates of g1ucose nonfermentative gram negative bacilli with reduced susceptability against imipenem (MIC≥8 μg/mL), EDTA-double disk synergy (EDTA-DDS), Etest MBL and modified Hodge test were compared with PCR detection method for MBLs. Results: Among 50 isolates of glucose nonfermentative microorganisms, eight MBL producers including a Pseudomonas aeruginosa and 7 Alcaligenes xylosoxidans were detected. Those isolates were VIM-2 producer. The results of EDTA-DDS and Etest MBL completely agreed with PCR for MBL detection. Two isolates among eight MBL Producers were not detected in modified Hodge test. Conclusion: All of MBL producing bacteria were VIM-2 genotype. In conclusion, EDTA-DDS may be useful method for MBL detection in clinical laboratory due to high cost of Etest MBL strip.

부착단백질이 사람 치수세포의 부착 및 증식에 미치는 영향에 관한 연구

신영주,최호영,민병순,박상진,최기운 慶熙大學校 齒科大學 1995 慶熙齒大論文集 Vol.17 No.2

The purpose of this vitro study was to evaluate attachment and proliferation of human pulpal cells to the attachment glycoprotein-coated and non-coated culture dishes. Well known adhesive glycoproteins were used, such as type I collagen, type IV collagen, fibronectin, laminin, and vitronectin. Each adhesive glycoproteins applied onto the culture dishes. In this study, the protein coated and non-coated dishes were classified as each groups. Human pulpal cells cultured onto each culture dishes. After 90 minute, 4 hour and 24 hour incubation attached cells in each group were counted with hematocytometer for evaluation of the attachment of human pulpal cells. The configurations of attached human pulpal cells were done by SEM observation. The results as follows 1. After 90 minute incubation the score of attachment of human pulpal cells was best in laminin-coated group among groups. Then fibronectin, type IV collagen group were better, and allproteins were higher than control. 2. After 4 hour incubation the numbers of attachment of human pulpal cells were most in fibronectin coated group. 3. After 24 hour incubation all of adhesive glycoproteins showed high and similar attachment effect to human pulpal cells. 4. In SEM observation, fibronectin and type IV collagen groups showed well spreaded human pulpal cells, then laminin group was moderately spreaded, and vitronectin group was mildly spreaded as well as control group.

골반 골절 환자에 있어서 골절 위치에 따른 하부 요로 손상의 연관성

신대은,문형윤,박성운,노준 朝鮮大學校 附設 醫學硏究所 2008 The Medical Journal of Chosun University Vol.33 No.3

Background and Objectives: Lower urinary tract injuries in pelvic bone fracture can lead to significant complication. We tried to find out the relationship between the fracture location and the bladder, urethra injury in patients who sustaining pelvic bone fracture. We thought that the fracture locations could serves as markers for injury. Materials and Methods: A clinical study was made on 43 patients who sustaining pelvic bone fracture with bladder or urethra injury in the Chosun University hospital during the period of 5 years from January, 2002 to December 2006. Diagnosis was done by retrograde cystography, retrograde urethragraphy, abdomenpelvic computed tomography. Results: Of the 43 patients reviewed, 27 patients had intraperitoneal type bladder rupture, and 12 patients had extra-peritoneal type bladder rupture. 9 patients had urethral rupture. Intraperitoneal type bladder rupture cases are most commonly associated with infrapubic ramus, suprapubic ramus and acetabulum. but the statistically significance is abscent (p= 0.642). Also extraperitoneal type bladder rupture cases are most commonly associated with infrapubic ramus, suprapubic ramus and acetabulum. but the statistically significance is abscent (p= 0.548). And all type bladder rupture cases are most commonly associated with infrapubic ramus, suprapubic ramus and acetabulum. but the statistically significance is abscent (p= 0.775). And urethral rupture cases are most commonly associated with infrapubic ramus, suprapubic ramus and acetabulum but the statistically significance is abscent (p= 0.528). Lastly, Combineded bladder rupture and urethral rupture cases are most commonly associated with infrapubic ramus, llium, Symphysis pubis. But the statistically significance is abscent (p= 0.462). Conclusions: In our study when there is a pelvic bone fracture, the fractured site of pelvic bone have no statistically association with lower urinary tract injury. But most common pelvic bone fracture site of all lower urinary tract injury cases is infrapubic ramus. Therefore, if infrapubic ramus fracture is found in the condition of pelvic bone fracture, it is highly likely to have lower urinary tract injury. More careful observation and diagnosis is necessary for this case.

GA를 이용한 다층 퍼셉트론 분류기의 구조 학습

신성효,김상운 明知大學校 産業技術硏究所 1995 産業技術硏究所論文集 Vol.14 No.-

In this paper a structural learning method for Multi-Layered Perceptron(MLP) classifiers using Genetic Algorithm(GA) is proposed. The method consists of two stages : candidate-structure-extraction and node-link-pruning. The first stare generates automatically the candidate structure of MLP classifier for a given problem. Then the second stage prunes off the non-useful nodes of the structure for obtaining the near-optimal one. To evaluate the proposed method we experiment with three kinds of data set : two dimension's XOR four dimension's IRIS, and eight dimensional handwritten-digit NUMBER. Experimental results show that our method could generate a task-related MLP structure which does not contain unimportant nodes, and could decrease the teaming time by 50 % without degrading the classification ratio.

다구치법에 의한 고 규소 내산주철의 용해주조공정 최적화

신제식,이상목,문병문,김정철,한동운,백승한 대한금속재료학회 2005 대한금속·재료학회지 Vol.43 No.2

In this study, Taguchi method, one of the design tools of experiments, was applied to optimize casting process parameters of the high silicon corrosion-resistant iron. Three casting process parameters such as melting temperature, rare earth metal (mischmetal) addition, and pouring temperature were chosen. Using SN (signal-to-noise) ratio calculated from ultimate tensile strength of each experimental casting run, the relationship between the casting parameters and mechanical properties was statistically evaluated. The casting condition of a melting temperature of 1,650℃, 0.2% rare earth metal addition, and a pouring temperature of 1,350℃ led to an excellent ultimate tensile strength above 11 kgf/mm², which is beyond the industrial criterion. The effects of the casting parameters on mechanical properties and corrosion resistance were further confirmed by combined analysis of fractography, hydrogen content determination, microscopic test, and acid resistance test. (Received August 23, 2004)

태권도 경기력 향상을 위한 효율적인 훈련 방법 조사 연구

백경운,신성득 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.20 No.1

The study was nudertaken to determine a specifics of physical fitness and training meth-od performance in Taekwondo. For the purpose the study was measured the physical fit-ness and physique through muscle strength, power, endurence, agility, blance and the'num-ber of heart rate. 1. Physique charc ateristics of height, weight, girth of chest, length of arm and lenght of leg were divided as 2 kinds of heavier class(A,B class) and lighter class(C, D). 2. In phyical fitness if muscngth, power, muscle endurence and agility showed very higher than of previous studies respectively. 3. In the resurt of measurement of heart rate, after exercise, training came out of higher or more and less than that of after skill training. 4. On the basis of experiment and literature reviews, physical fitness and training pro-gram was built by 5 grade.