새마을 運動 實績評價模型 作成에 관한 硏究

黃明燦,玄斗日,梁始浩,朴英熙,金龍國,申大淳 건국대학교 1974 學術誌 Vol.17 No.1

The New Village (Sae-ma-eul) movement is Korean version of Community Development that has under-gone widespread exploration, experimentation and application in developing countries throughout the world in recent years. In most countries the national governments have undertaken the iniative in Community Development through appropriate ministries or special agencies. The New Village Movement was initiated in 1970 by Korean government. But it became a people's movement for self-development as more and more people participated in the developmental programs. The major objectives of the New Village movement are to redress the economic disparities between the rural and urban areas by improving the economic, social and cultural conditions of rural Communities, to reform the way of life in rural villages by encouraging the attitude of self-help, and to increase the income of the farmers and fisher man. Since 1971, An enormous amount of public and priate money has been invested into the New Village Movement. It seems that the time has arrived when some framework for evaluating the whole program is to be developed. Thus, The objective of this study is to develop an appropriate to evaluate the new village project at the village level. Ten major factors which are supposed to be relevant for evaluation of the project was selected. The evaluation model thus developed can be summarized in the following format. ◁표 삽입▷ (원문을 참조하세요)

카드뮴 첨가된 α형 산화철에 의한 일산화탄소의 촉매산화 반응연구

이성한,김용록,김돈,정원양,김규홍,최재시 연세대학교 자연과학연구소 1983 學術論文集 Vol.11 No.-

α형 산화철에 카드뮴을 4mol%, 8mol% 및 12mol%로 각각 첨가시켜 외성영역의 특성을 갖는 산화물들을 제조하였다. 이 산화물들을 촉매로한 일산화탄소의 산화반응 속도론적 연구를 통하여 본산화물의 결함구조, CO 산화반응에 대한 촉매성 및 불순물 첨가효과등을 조사하였다. 또한 450℃에서 O_2 및 CO를 여러압력으로 도입시켜 Cd-doped α-Fe_2O_3의 전기전도도를 측정하고 이를 반응속도론적 데이타와 결부시켜 본산화물상에서 CO 의 산화반응 메카니즘과 율속단계를 제안하였다. 반응온도범위 350~460℃에서 산출된 활성화에너지는 10.1~11.3kcal.mol^-1이었다. CO_2흡착에 의한 CO산화반응의 억제효과는 본실험의 반응온도 영역인 350~460℃에서는 나타나지 않았으며 CO 산화반응의 전반응속도 차수는 1.5차로서 일산화탄소에 대해서는 1차, 산소에 대해서는 0.5차임이 밝혀졌다. 반응속도론적 데이타와 전기전도도 데이타에 의해 본촉매의 활성은 카드뮴도프로 인해 생성된 산소공위(Vo"-2e^-)에 기인한 것이었다. 카드뮴의 첨가량이 증가할수록 반응속도는 증가하였으나 12mol% 이상의 카드뮴이 첨가된 산화철상에서는 반응속도가 크게 증가하지 않는 것으로 나타났다. CO와 O_2는 근본적으로 화학흡착하며 CO의 흡착자리는 격자산소(O^-2_(latt))와 기흡착원산소 (O^-_(ads)), 그리고 O_2의 흡착자리는 산소공위(Vo"-2e^-)로 밝혀졌다. The α-Ferric oxide containing 4, 8, and 12mol% with cadmium were prepared. The oxidation rates of carbon monoxide in the presence of these oxide systems were measured to investigate the defect structure, the catalytic activity for the oxidation of carbon monoxide, and the impurity effect. The conductivity was also measured at 450℃ under the various pressures of oxygen and carbon monoxide. From the agreement between the kinetic and conductivity data, the oxidation mechanism of carbon monoxide and the rate determining step on this oxide catalyst were suggested. In the temperature range from 350 to 460℃, the calculated activation energy for the CO oxidation over Cd-doped α-Fe_2O_3 systems were 10.1∼11.3kcal·mol^-1. The inhibition by an adsorbed CO_2 during the CO oxidation was not observed in the above temperature range. The overall reaction order for the CO oxidation is 1.5; the first order with respect to CO and the one-half order with respect to O_2. The catalytic activity of this oxide system is due to oxygen vacancies induced by Cd-doping. The oxidation rates increase with increasing the amount of dopant and above 12mol%, however, don't highly increased. CO and O_2 are essentially chemisorbed as ions and the adsorption sites for CO are the lattice oxygens (O^2-_(latt)) and prechemisorbed oxygens (O^-_(ads)), the adsorption site for O_2 is the oxygen vacancies (Vo¨-2e^-).

Surface-Displayed Porcine IFN-λ3 in Lactobacillus plantarum Inhibits Porcine Enteric Coronavirus Infection of Porcine Intestinal Epithelial Cells

Yong-Shi Liu,Qiong Liu,Yanlong Jiang,Wentao Yang,Hai-Bin Huang,Chun-Wei Shi,Gui-Lian Yang,Chun-Feng Wang 한국미생물·생명공학회 2020 Journal of microbiology and biotechnology Vol.30 No.4

Interferon (IFN)-λ plays an essential role in mucosal cells which exhibit strong antiviral activity. Lactobacillus plantarum (L. plantarum) has substantial application potential in the food and medical industries because of its probiotic properties. Alphacoronaviruses, especially porcine epidemic diarrhea virus (PEDV) and transmissible gastroenteritis virus (TGEV), cause high morbidity and mortality in piglets resulting in economic loss. Co-infection by these two viruses is becoming increasingly frequent. Therefore, it is particularly important to develop a new drug to prevent diarrhea infected with mixed viruses in piglets. In this study, we first constructed an anchored expression vector with CWA (C-terminal cell wall anchor) on L. plantarum. Second, we constructed two recombinant L. plantarum strains that anchored IFN-λ3 via pgsA (N-terminal transmembrane anchor) and CWA. Third, we demonstrated that both recombinant strains possess strong antiviral effects against coronavirus infection in the intestinal porcine epithelial cell line J2 (IPEC-J2). However, recombinant L. plantarum with the CWA anchor exhibited a more powerful antiviral effect than recombinant L. plantarum with pgsA. Consistent with this finding, Lb.plantarum-pSIP-409-IFN- λ3-CWA enhanced the expression levels of IFN-stimulated genes (ISGs) (ISG15, OASL, and Mx1) in IPEC-J2 cells more than did recombinant Lb.plantarum-pSIP-409-pgsA'-IFN-λ3. Our study verifies that recombinant L. plantarum inhibits PEDV and TGEV infection in IPEC-J2 cells, which may offer great potential for use as a novel oral antiviral agent in therapeutic applications for combating porcine epidemic diarrhea and transmissible gastroenteritis. This study is the first to show that recombinant L. plantarum suppresses PEDV and TGEV infection of IPEC-J2 cells.

A Study of Sustainable Development on Rural Ondol Residence in the Northeast of China

Shi Jun Sun,Yong Yang,Yun Duo Zhao 국제온돌학회 2006 International Journal of Ondol Vol.1 No.1

As we all know Ondol has been the most efficient and comfortable heating system of the rural residence in the Northeast of China for hundreds of years. But recently, through field survey, it was found that some country people replace the Ondol with homemade heating blindly. The result of this replacement is that heating effect of residence in winter is worse. And at the same time, it aggravates air pollution and increases heating payout. According to our real situation of energy sources reserve, environmental pollution and economic income of rural people, it is not only inpractical but also unreasonable, that in the northeast of China Ondol is replaced by homemade heating completely in winter. Ondol has its unique heating and hygienic efficacy. And it stands for cultural tradition and life custom of the country's cold areas. So we should improve Ondol combining resident structure and material. And it can make the Ondol system flourish with vigor and promote sustainable development of the country's traditional Ondol residence.

Differential Impacts on Bacterial Composition and Abundance in Rhizosphere Compartments between Al-Tolerant and Al-Sensitive Soybean Genotypes in Acidic Soil

Wen Zhong-Ling,Yang Min-Kai,Fazal Aliya,Liao Yong-Hui,Cheng Lin-Run,Hua Xiao-Mei,Hu Dong-Qing,Shi Ji-Sen,Yang Rong-Wu,Lu Gui-Hua,Qi Jin-Liang,Zhi Hong,Qian Qiu-Ping,Yang Yong-Hua 한국미생물·생명공학회 2020 Journal of microbiology and biotechnology Vol.30 No.8

In this study, two soybean genotypes, i.e., aluminum-tolerant Baxi 10 (BX10) and aluminumsensitive Bendi 2 (BD2), were used as plant materials and acidic red soil was used as growth medium. The soil layers from the inside to the outside of the root are: rhizospheric soil after washing (WRH), rhizospheric soil after brushing (BRH) and rhizospheric soil at two sides (SRH), respectively. The rhizosphere bacterial communities were analyzed by high-throughput sequencing of V4 hypervariable regions of 16S rRNA gene amplicons via Illumina MiSeq. The results of alpha diversity analysis showed that the BRH and SRH of BX10 were significantly lower in community richness than that of BD2, while the WRH exhibited no significant difference between BX10 and BD2. Among the three sampling compartments of the same soybean genotype, WRH had the lowest community richness and diversity while showing the highest coverage. Beta diversity analysis results displayed no significant difference for any compartment between the two genotypes, or among the three different sampling compartments for any same soybean genotype. However, the relative abundance of major bacterial taxa, specifically nitrogen-fixing and/or aluminum-tolerant bacteria, was significantly different in the compartments of the BRH and/or SRH at phylum and genus levels, indicating genotype-dependent variations in rhizosphere bacterial communities. Strikingly, as compared with BRH and SRH, the WRH within the same genotype (BX10 or BD2) always had an enrichment effect on rhizosphere bacteria associated with nitrogen fixation

rs10505474 and rs7837328 at 8q24 Cumulatively Confer Risk of Prostate Cancer in Northern Han Chinese

Zhang, Lin-Lin,Sun, Liang,Zhu, Xiao-Quan,Xu, Yong,Yang, Kuo,Yang, Fan,Yang, Yi-Ge,Chen, Guo-Qiang,Fu, Ji-Cheng,Zheng, Chen-Guang,Li, Ying,Mu, Xiao-Qiu,Shi, Xiao-Hong,Zhao, Fan,Wang, Fei,Yang, Ze,Wang, Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.7

Aims: Genome-wide association studies (GWAS) have identified several risk variants for prostate cancer (pCa) mainly in Europeans, which need to be further verified in other racial groups. We selected six previously identified variants as candidates and to define the association with PCa in Northern Han Chinese. Methods: 749 subjects from Beijing and Tianjin in Northern China were included. Six variants (rs10505474, rs7837328, rs4242384, rs7813, rs486907 and rs1058205) were genotyped by high resolution melting (HRM) assays. The individual and cumulative contribution for of the risk of PCa and clinical covariates were analyzed. Results: Among the six candidate variants, onlyrs10505474, and rs7837328, both locating at 8q24 region, were associated with PCa in our population.rs10505474 (A) was associated with PCa ($OR_{recessive}=1.56$, p=0.006); and rs7837328 (A) was associated with PCa ($OR_{dominant}=1.38$, p=0.042/$OR_{recessive}=1.99$, p=0.003). Moreover, we observed a cumulative effects between them ($p_{trend}=2.58{\times}10^{-5}$). The joint population attributable risk showed the two variants might account for 71.85% of PCa risk. In addition, we found the homozygotes of rs10505474 (A) and rs7837328 (A) were associated with PCa clinical covariants (age at onset, tumor stage, respectively) ($p_{age}=0.046$, $P_{tumorstage}=0.048$). Conclusion: rs10505474 (A) and rs7387328 (A) at 8q24 are associated with PCa and cumulatively confer risk, suggesting the two variations could determine susceptibility to PCa in the Northern Chinese Han population.

Insect-specific microRNA involved in the development of the silkworm Bombyx mori

Yong Zhang,Xue Zhou,Xie Ge,Jiang-Hao Jiang,Mu-Wang Li,Shi-Hai Jia,Xiao-Nan Yang,Yun-Chao Kan,Xue-Xia Miao,Guo-Ping Zhao,Fei Li,Yong-Ping Huang 한국응용곤충학회 2009 한국응용곤충학회 학술대회논문집 Vol.2009 No.10

MicroRNAs (miRNAs) are endogenous non-coding genes that participate in post-transcription regulation by either degrading mRNA or blocking its translation. It is considered to be very important in regulating insect development and metamorphosis. Insects are the largest group of animals and are extremely valuable in biological and agriculture research. Insects are also important pests to human health and agriculture, and efforts are necessary protect both humans and plants from disease and damage. Despite their importance, insects lag behind mammals, nematodes, and plants in miRNA research. At present, only 279 insect miRNAs have been identified from Drosophila melanogaster, Anopheles gambiae, Apis mellifera, Bombyx mori, and D. pseudoobscura in miRBase, and most of these miRNAs were computationally predicted without experimental validation. Functional analysis of insect miRNAs has only been conducted in D. melanogaster.

Designing Redox-Stable Cobalt-Polypyridyl Complexes for Redox Flow Batteries: Spin-Crossover Delocalizes Excess Charge

Yang, Chunzhen,Nikiforidis, Georgios,Park, Ji Young,Choi, Jonghoon,Luo, Yong,Zhang, Liang,Wang, Shi-Cheng,Chan, Yi-Tsu,Lim, Jihun,Hou, Zhaomin,Baik, Mu-Hyun,Lee, Yunho,Byon, Hye Ryung Wiley Blackwell (John Wiley Sons) 2018 Advanced energy materials Vol.8 No.14

Perturbative studies of toroidal momentum transport in KSTAR H-mode and the effect of ion temperature perturbation

Yang, S.M.,Na, Yong-Su,Na, D.H.,Park, J.-K.,Shi, Y.J.,Ko, W.H.,Lee, S.G.,Hahm, T.S. International Atomic Energy Agency 2018 Nuclear fusion Vol.58 No.6

<P>Perturbative experiments have been carried out using tangential neutral beam injection (NBI) and non-resonant magnetic perturbation (NRMP) to analyze the momentum transport properties in KSTAR H-modes. Diffusive and non-diffusive terms of momentum transport are evaluated from the transient analysis. Although the operating conditions and methodologies applied in the two cases are similar, the momentum transport properties obtained show clear differences. The estimated momentum diffusivity and pinch obtained in the NBI modulation experiments is larger than that in the NRMP modulation experiments. We found that this discrepancy could be a result of uncertainties in the assumption for the analysis. By introducing time varying momentum transport coefficients depending on the temperature gradient, the linearized equation shows that if the temperature perturbation exists, the evolution of toroidal rotation perturbation could be faster than the transport rate of mean quantity, since the evolution of toroidal rotation perturbation is related to <img ALIGN='MIDDLE' ALT='' SRC='http://ej.iop.org/images/0029-5515/58/6/066008/nfaab90eieqn001.gif'/>, a momentum diffusivity from perturbative analysis. This could explain the estimated higher momentum diffusivity using time independent transport coefficients in NBI experiments with higher ion temperature perturbation compared to that in NRMP modulation experiments. The differences in the momentum transport coefficient with NRMP and NBI are much reduced by considering time varying momentum transport coefficients in the time dependent transport simulation.</P>

Optimized Transformation of Streptomyces sp. ATCC 39366 Producing Leptomycin by Electroporation

Yong-Qiang Fan,Hong-Jian Liu,Li Yan,Yu-Shi Luan,Hai-Meng Zhou,Jun-Mo Yang,Shang-Jun Yin,Yu-Long Wang 한국미생물학회 2013 The journal of microbiology Vol.51 No.3

Streptomyces sp. ATCC 39366 produces leptomycin derivatives. Leptomycin B, a potent and specific inhibitor against the export of nuclear proteins, is the main product; however, the introduction of DNA into this strain is almost impossible, which has impeded its further use. We developed a Streptomyces sp. ATCC 39366 transformation protocol to introduce foreign DNA via electroporation. Various conditions were examined, including treatments of the cell wall with weakening agents, electroporation parameters, and DNA content. We found that only plasmid DNA isolated from a dam- ET12567 strain resulted in successful transformation. The mycelium growing in a yeast-peptone-dextrose medium supplemented with 1% glycine at 28°C on a rotary shaker (220 rpm) was more dispersed than those without supplementation and prone to electroporation. The maximum transformation efficiency of 8×102 CFU/μg plasmid DNA was obtained at a field strength of 13 kV/cm with a time constant of 13 ms (25-μF capacitor; parallel resistance, 600 Ω) using 1-mm electrocuvettes. The results of the transformations of two other Streptomyces species indicated that the optimized conditions established in this study might only be applicable to Streptomyces sp. ATCC 39366. However, this is the first report of successful transformation of Streptomyces sp. ATCC 39366, and will facilitate the construction of a gene knockout mutant in Streptomyces sp. ATCC 39366 to produce series of new leptomycin derivatives.