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      • KCI등재

        한화(漢畵) 시각디자인 관련 빅데이터 텍스트 분석 : 중국 소셜미디어를 중심으로

        황산산(Huang, Shan Shan),신인식(Shin, In Sik) 한국디자인리서치학회 2021 한국디자인리서치 Vol.6 No.1

        최근 몇 년 사이 한화(漢畵) 하나의 무형문화유산으로서 중국 정부기관의 대대적인 보호와 지원을 받고 있으며 이에 따라 한화 요소를 포함한 시각디자인도 점차 대중들 사이에서 인지도가 상승하고 있다. 본 연구는 중국 온라인 소셜미디어 및 플랫폼을 통해 텍스트 데이터를 수집하여 분석하였으며 연구 결과는 다음과 같다.첫째, 최근 3년간 수집한 소셜미디어 글 총 6,571건에서 추출한 키워드는 총 131,978개로, 그중 출현횟수가 230회 이상인 주요 키워드 60개를 선정했다. 출현횟수가 3,000회 이상인 키워드 중 ‘한화(漢畵)’(15,929회)의 출현빈도가 가장 높았으며, 그다음으로는 ‘시각디자인’(13,396회)등 가장 영향력 있는 키워드 15개를 텍스트 데이터의 토대로 삼았다. 둘째, ‘한화’ 시각디자인 관련 주요 키워드 간의 텍스트 연결망의 연결 중심성 분석을 실시한 결과, ‘한화’(15,929회)와 ‘시각디자인’(13,396회)의 노드 수가 압도적으로 많았으며, 이 노드들은 소셜미디어를 통해 ‘한화’에 대한 반응을 연구하는 중요한 이유다. 셋째, Ucinet 프로그램을 통해 CONCOR 분석을 실시한 결과, ‘한화’ 시각디자인 관련 주요 키워드 사이에 구조적 등위성을 지닌 단어들을 클러스터링(군집화)하여 네트워크를 시각화한 결과, 최종적으로 4개의 클러스터(그룹)를 형성했다. 넷째, 상기 4개 그룹을 대상으로 의미연결망 분석을 실시한 결과, 2그룹, 3그룹, 4그룹은 모두 1그룹에 속한 단어인 ‘한화’, ‘시각디자인’의 구성 부분임을 알 수 있었으며 인터뷰, 설문조사 및 통계 등 연구 방법에 비해 더 효율적이고 유의미한 연구 결과를 도출할 수 있었다. In recent years, as an intangible cultural heritage of Hanwha, it has been receiving massive protection and support from Chinese government agencies, and as a result, visual design including Hanwha elements has been gradually gaining popularity among the public. This study collected and analyzed textual data through Chinese online social media and platforms, and the results of the study were as follows.First, a total of 131,978 keywords were extracted from a total of 6,571 social media writings collected over the past three years, of which 60 major keywords with more than 230 appearances were selected. Among the keywords that appeared more than 3,000 times, Hanhwa (15,929 times), visual design (13,396 times) appeared the most frequently, followed by 15 most influential keywords . Second, after analyzing the centrality of the text link between major keywords related to Hanwha visual design, the number of nodes in Hanwha (15,929 times), visual design (13,396 times) was overwhelmingly high. This is why we study responses to Hanwha through social media. Third, the results of CONCOR analysis through the Ucinet program resulted in clustering (colonizing) the network of words with structural equivalence between the key keywords related to Hanwha visual design, eventually forming four clusters (groups). Fourth, the four groups analyzed meaningful Internet connections for the objects, and the second, third, and fourth groups were all part of the words Hanwha and visual design that belonged to the first group. Compared with research methods such as interviews, questionnaires, and statistics, this method of analysis produces more effective and meaningful results.

      • KCI등재

        Hypolipidemic and Antioxidant Effects of Malus toringoides (Rehd.) Hughes Leaves in High-Fat-Diet-Induced Hyperlipidemic Rats

        Shan Huang,Haifeng Liu,Ning Meng,Bin Li,Jule Wang 한국식품영양과학회 2017 Journal of medicinal food Vol.20 No.3

        Malus toringoides (Rehd.) Hughes (MT) leaves are traditionally used as a medicine for treating or preventing cardiovascular disease in Tibet. In addition to the effect of this medicinal plant on thrombosis, we tested its effect on dyslipidemia in a hypolipidemic rat model. A total of 60 healthy Sprague-Dawley rats were randomly divided into six groups, as follows: normal control, model control, simvastatin groups, and MT low-, medium-, and high-dose groups. The normal controls were fed with a normal diet, whereas all other groups were fed with a high-fat diet. After 6 weeks, the high-fat diet had induced hyperlipidemia in the rats, which were then orally administered with different doses of MT leaf extract (50, 100, and 200 mg/kg) for an additional 6 weeks. Serum levels of total cholesterol (TC), triglycerides (TG), low- and high-density lipoprotein cholesterol (LDL-c and HDL-c, respectively), as well as the antioxidant capacity of glutathione peroxidase (GSHP-x), superoxide dismutase (SOD), and malondialdehyde (MDA) were measured at the end of the study. MT significantly reduced serum TC, TG, and LDL-c and increased the HDL-c content in MT-treated rats compared with the model group. These changes were dose dependent. MT treatment also significantly elevated the activity of SOD and GSHP-x, and decreased the serum levels of MDA compared with untreated hyperlipidemic rats, thereby increasing serum antioxidant capacity. In addition, MT reduced liver steatosis in hyperlipidemic rats. Overall, MT exerts considerable hypolipidemic and antioxidant properties.

      • KCI등재후보

        Application of magnetic field to iron contained dust capture

        Huang, Shan,Park, Hae-Woo,Jo, Young-Min,Park, Young-Koo,Kim, Youn-Che The Korean Society of Applied Science and Technolo 2014 한국응용과학기술학회지 Vol.31 No.1

        Indoor air quality including metro subway is of recent interests in large cities. Inflow air to the inside of the train and circulating air flow through MVAC of stations contain large amount of iron based fine particles. This paper evaluated the collection of such a dust by magnetic filters as comparing to conventional particle capturing mechanisms such as inertia, direct impaction and diffusion. It was found that filtration velocity, magnetic field intensity, and fiber size were the most important parameters for magnetic filtration. Application of magnetic force obviously enhances the collection efficiency particularly in fine modes smaller than 10 mm. However, its effect was found greater in 2.5 mm than submicron particles.

      • Decreased Expression of LKB1 Correlates with Poor Prognosis in Hepatocellular Carcinoma Patients Undergoing Hepatectomy

        Huang, Yue-Han,Chen, Zhen-Kun,Huang, Ka-Te,Li, Peng,He, Bin,Guo, Xu,Zhong, Jun-Qiao,Zhang, Qi-Yu,Shi, Hong-Qi,Song, Qi-Tong,Yu, Zheng-Ping,Shan, Yun-Feng Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.3

        Aim: To study any correlation of LKB1 expression with prognosis in hepatocellular carcinoma (HCC) cases. Methods: A total of 70 HCC patients and 20 primary intrahepatic stone patients in the first affiliated hospital of Wenzhou Medical College were enrolled in this study. LKB1 expression was detected by immunohistochemistry. Patients were followed-up and prognostic factors were evaluated. Result: LKB1 expression was decreased in the HCC samples. Loss of LKB1 expression in HCC was significantly related to histologic grade (P=0.010), vascular invasion (P=0.025) and TMN stage (P=0.011). Patients showing negative LKB1 expression had a significantly shorter disease-free and overall survival than those with positive expression (P = 0.001, P=0.000, respectively). Multivariate Cox regression analysis indicated that LKB1 expression level was an independent factor of survival (P = 0.033). Conclusion: HCC patients with decreased expression LKB1 have a poor prognosis. The loss of LKB1 expression is correlated with a lower survival rate.

      • KCI등재

        Phenotypic and genomic characteristics of Brevibacterium zhoupengii sp. nov., a novel halotolerant actinomycete isolated from bat feces

        Huang Yuyuan,Dong Lingzhi,Gong Jian,Yang Jing,Lu Shan,Lai Xin-He,Jin Dong,Huang Qianni,Pu Ji,Liu Liyun,Xu Jianguo 한국미생물학회 2022 The journal of microbiology Vol.60 No.10

        Two strictly aerobic, Gram-staining-positive, non-spore-forming, regular rod-shaped (approximately 0.7 × 1.9 mm) bacteria (HY170T and HY001) were isolated from bat feces collected from Chongzuo city, Guangxi province (22°20 54 N, 106°49 20 E, July 2011) and Chuxiong Yi Autonomous Prefecture, Yunnan province (25°09 10 N, 102°04 39 E, October 2013) of South China, respectively. Optimal growth is obtained at 25–28°C (range, 4–32°C) on BHI-5% sheep blood plate with pH 7.5 (range, 5.0–10.0) in the presence of 0.5– 1.0% NaCl (w/v) (range, 0–15% NaCl [w/v]). The phylogenetic and phylogenomic trees based respectively on the 16S rRNA gene and 845 core gene sequences revealed that the two strains formed a distinct lineage within the genus Brevibacterium, most closely related to B. aurantiacum NCDO 739T (16S rRNA similarity, both 98.5%; dDDH, 46.7–46.8%; ANI, 91.9–92.1%). Strain HY170T contained MK-8(H2), diphosphatidylglycerol (DPG) and phosphatidylglycerol (PG), galactose and ribose as the predominant menaquinone, major polar lipids, and main sugars in the cell wall teichoic acids, respectively. The meso-diaminopimelic acid (meso-DAP) was the diagnostic diamino acid of the peptidoglycan found in strain HY170T. Anteiso-C15:0 and anteiso-C17:0 were the major fatty acids (> 10%) of strains HY170T and HY001, with anteiso-C17:1A predominant in strain HY170T but absent in strain HY001. Mining the genomes revealed the presence of secondary metabolite biosynthesis gene clusters encoding for non-alpha poly-amino acids (NAPAA), ectoine, siderophore, and terpene. Based on results from the phylogenetic, chemotaxonomic and phenotypic analyses, the two strains could be classified as a novel species of the genus Brevibacterium, for which the name Brevibacterium zhoupengii sp. nov. is proposed (type strain HY170T = CGMCC 1.18600T = JCM 34230T).

      • KCI등재

        Cough Inhibition Activity of Schisandra chinensis in Guinea Pigs

        Shan Zhong,Li-Ping Bai,Xiao-Dong Liu,Die-Yi Cai,Lee-Fong Yau,Chu-Qin Huang,Jia-Qi Zhang,Ke-Fang Lai,Nan-Shan Zhong 한국식품영양과학회 2021 Journal of medicinal food Vol.24 No.4

        Chronic cough is very common in respiratory clinics, and no effective drugs are available. Schisandra chinensis (Turcz.) Baill. (S. chinensis), an important traditional Chinese medicine, has been extensively prescribed for patients with a persistent cough. Preliminary research indicated that 95% ethanol extracts (EE) of S. chinensis showed remarkable antitussive activity in guinea pigs exposed to cigarette smoke (CS). To find out the antitussive ingredients of S. chinensis, EE was divided into four fractions according to the polarity: petroleum ether extract (PEE), ethyl acetate extract (ECE), n-butyl alcohol extract, and residue extract. The antitussive, antioxidant, and anti-inflammatory effects of the four fractions were evaluated in a guinea pig model of cough hypersensitivity induced by CS exposure. Eighteen main constituents of the two effective fractions, PEE and ECE, were identified using ultra-high-pressure liquid chromatography electronic spray ion time-of-flight mass spectrometry. The cough inhibition activities of compound 1, 3, 9, 10, 17 were evaluated on citric acid induced acute cough guinea pigs. The results showed that the antitussive activity of EE was almost all contained in PEE and ECE. The 16 major peaks in PEE were identified as 15 lignans (1–12 and 14–16) and 1 triterpene (compound 13), and 3 major peaks (1, 17, and 18) in ECE were also identified as lignans. Three doses of five compounds brought about a significant decrease in number of cough efforts (P < .01), and the cough inhibition rates were between 40.9% and 85.1%. Therefore, lignans are the antitussive ingredients of S. chinensis.

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