Flavobacterium meningosepticum에 의한 균혈증 1예

장성원,유진홍,진승원,김선우,김연식,박순민,이대훈,최민호,최주연,신완식,강문원,강지민 대한화학요법학회 1997 대한화학요법학회지 Vol.15 No.1

1996년 6월 카톨릭대학교 부천성가병원에 뇌경색으로 입원했던 61세 남자 환자의 혈액에서 Flavobacterium meningosepticum을 분리하였다. 환자는 폐렴을 동반한 패혈증의 예로 ceftriaxone과 metronidazole을 투여하였으나 입원 48시간만에 사망하였다. Flabovacterium meningosepticum is a rae cause of nosocomial infection which shows multi-drug resistance. It mainly invades patients with impaired immunity. Recently, we experienced a case of F. meningosepticum bacteremia in a patient with chronic debilitated state owing to stroke. The clinical progress was so rapid that he died within 48 hours. Blood culture revealed F. meningosepticum which showed characteristic yellow colony in blood agar plate.

c-형강 및 ebb & flow 방식에 따른 경제성 분석

강승원(Seung Won Kang),박천호(Chun Ho Pak),조용성(Yong Sung Cho) 한국원예학회 2007 원예과학기술지 Vol.25 No.3

관비재배와 저면관수인 ebb & flow, C-형강의 재배방식에 따른 고품질분화 생산을 위한 재배농가의 경제성을 분석하였다. 이를 위해 화훼농가의 비용구조를 분석하였고 자본 회수기간 및 내부수익률의 추정, 관수에 따른 인건비 절감 효과를 분석하여 재배방식에 따른 경제성을 비교하였다. 10a(991.7m²) 규모의 자동온실에 대해 관비재배방식을 선택한 시클라멘 재배농가의 총 비용은 9,993.8만원으로 추정되며, 이 중 시설비는 74%(7,410만원)를 점하고 연간 2,583.8만원의 경영비를 지출할 것으로 예상된다. 반면, C-형강방식을 선택한 재배농가는 초기 시설비용으로 약 8,520.0만원(총비용의 약 70%)을 지출하고, 매년 경영비로 3,597.0만원을 지출할 것으로 추정된다. 한편, 투자자금에 대한 자본회수 기간을 분석한 결과 10a 규모의 자동온실에서 시클라멘을 재배하는 농가에서 관비재배방식 혹은 C-형강방식을 선택할 경우에는 초기시설투자비 회수기간이 약 4 년 정도 소요될 것으로 예측되며, ebb & flow 방식을 선택할 경우에는 약 5년 정도의 시간이 소요될 것으로 예상된다. 또한, 내부 수익률을 추정한 결과 ebb & flow시설과 C-형강시설을 5년과 6년씩 사용한다고 가정할 경우, ebb & flow시설의 내부 수익률은 각각 9%와 14%로 나타났고, C-형강시설의 경우에는 각각 13%와 17%로 나타나 시중의 저축성예금 수신금리 4.82%와 비교하여 경제성이 높은 것으로 분석되었다. Economical efficiency for production of high quality-potted plants was analyzed by types of irrigation system such as conventional fertigation, ebb & flow, and C-channel as subirrigation systems. After cost structure was analyzed, payback period of capital, internal rate return (IRR), and effects of reduced labor cost were estimated. The gross cost of cyclamen-producing farmers using hydroponic systems in automated greenhouses (10a) was about 100 million won. Of the gross cost, installation and operation costs occupied 74% and 25%, respectively. In the C-channel subirrigation system, gross cost was 120 million won approximately. Installation and operation costs occupied 70% and 30%, respectively. Payback period of capital was 4 years for fertigated irrigation and C-channel subirrigation system, whereas it was 5 years for ebb & flow. IRR of ebb & flow and C-channel subirrigation systems was higher than the interest rates of 4.82%, indicating economic efficiency.

Impact of Interferon-Based Treatment on Quality of Life and Work Related Productivity from the Korean Cohort in the MOSAIC Study

( Sang Hoon Ahn ),( Won Hyeok Choe ),( Yoon Jun Kim ),( Jeong Heo ),( Dorota Latarska-smuga ),( Jiho Kang ),( Seung Woon Paik ) 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1

Aims: Chronic Hepatitis C Virus (HCV) infection increases the risk for progressive liver disease, hepatocellular carcinoma and negatively impacts the patient’s quality of life. HCV treatment is evolving with direct acting antivirals but IFN based therapy has been the standard of care for many years and remains available in some countries. The MOSAIC study aims to characterize patients with chronic HCV infection and assess the impact of IFN-containing treatment on health-related quality of life, work related productivity and health care utilization. Methods: MOSAIC is an international prospective multicenter observational study that has been conducted in 20 countries. Consecutive patients with chronic HCV infection were enrolled and those who initiated an IFN based regimen were prospectively followed for 48 weeks. We report results from the Korean cohort Results: 100 patients were enrolled: 86 were treatment naïve and 14 were treatment experienced. 33 patients initiated an IFN based regimen: 6 patients started IFN + RBV, 26 patients started Peg-IFN + RBV, none started Peg-IFN + RBV + DAA and 1 patient received other treatment. Among the treated cohort, demographic and disease characteristics were the following: the mean age was 54.5 years; 14 patients were male. 14 had minimal or no fibrosis, 2 portal fibrosis, 3 bridging fibrosis and 6 patients suffered from cirrhosis. HCV Genotype distribution was as follows: genotype 1: 11; genotype 2: 19 and genotype 3: 3. Table 1 describes the results at baseline and changes over 4, 12 and 48 weeks and end-of-treatment (EOT) for the quality of life and work productivity outcome measures (EQ-5D-5L, HCV-PRO and WPAI). Conclusions: Results from the Korean cohort of the MOSAIC study show a moderate trend for deterioration of health-related quality of life and work productivity associated with IFN based treatment for patients with chronic HCV infection during treatment period. Acknowledgements: The design, study conduct, analysis, and financial support of MOSAIC study were provided by AbbVie. AbbVie participated in the interpretation of data, review, and approval of the content of the abstract. All authors had access to all relevant data and participated in writing, review, and approval of this abstract. Medical writing support was provided by Olivier Van de Steen of Medeor-consulting, funded by AbbVie. Disclosures: Sang Hoon Ahn: served as an advisor and lecturer for Bristol-Myers Squibb, Gilead Sciences, F.Hoffmann-La Roche, Merck, AbbVie, and has received unrestricted grants from Bristol-Myers Squibb, Gilead Sciences, and F. Hoffmann-La Roche for investigator- initiated trials Won Hyeok Choe: Nothing to disclosure Yoon Jun Kim: Nothing to disclosure Jeong Heo: received a grant from GSK; Research support from BMS, and Roche; Advisor for Abbvie, BMS, Gilead Sciences, Pharma Essentia, SillaJen, and Johnson & Johnson. Dorota Latarska-Smuga, Jiho Kang: are employees of AbbVie, Inc. and may hold stock or stock options. Seung Woon Paik: received grant and research support from AbbVie, BMS, Gilead, GSK, Merck, Novartis, and Roche

목포해역의 확산양상

강주환,박선중,문승록,박민원 국립7개대학공동논문집간행위원회 2005 공업기술연구 Vol.5 No.-

Tidal currents had been reduced remarkably since the constructions of Youngsan River Seadike and Youngam/Keumho Seawalls at the semi-enclosed Mokpo coastal zone. This deteriorates the water quality of the zone seriously, because reduced currents prevent pollutants flushing out or diluting easily. Three cases are simulated numerically with HD and AD modules of the MIKE21 software; continuously pollutants discharging case at Mokpo Harbor, intermittent discharging case at the gate of the Seadike, and continuously pollutants discharging case at Chungkye Bay. The results of all the cases show that the majority of the pollutants does not flush out but remains at Mokpo coastal zone. Especially, the release from gates of the Seadike may cause that fresh water concentration prevails near Mokpo Harbor.

국내 석유가격변동 예측모형에 관한 연구

강승원 우송대학교 2004 우송대학교 논문집 Vol.9 No.-

Petroleum is considered as one of the most important energy sources of our nation, which price has been determined at the free market with any regulation since 1997. Based on free determined petroleum price scheme, domestic refining companies could adjust the price to international oil price and domestic demand factor's changes. The main purpose of this study is to set up the forecasting model for oil price. The error correction model is considered to conduct oil price forecasting and empirically is implemented to make a judgement for oil price. The results could be used as a data for discussing whether oil price adjustment would be appropriate or not.

생쥐 중이와 상기도 점막의 섬모세포운동

정하원,오승하,유원석,이강수,모지훈,전상준,김인상,김종선 대한이비인후과학회 1999 대한이비인후과학회지 두경부외과학 Vol.42 No.9

얇은 도핑조절 a-Si:H초격자에서 지속 광전기 전도도

康聖洙,梁承勳,李原鎭,金英鳳,孔維庠,朴相俊,崔時永 慶北大學校 1990 論文集 Vol.49 No.-

Very large PPC effect(σ_ppc/σ_A=10^5) in doping-modulated npnp a-Si: H superlattices could be obtained. B and P atoms, respectively, diffuse and so some parts compensated. Therefore, annealing activation energy of E_a=0.67eV is larger than one of reference n-type sample of E_a=0.26eV and annealing dark conductivity of σ_A=4×10^-[ohm cm]^-1 is lower than that of n-type reference sample of σ_A=2×10 exp (4)[ohm cm]^-1. From this results, very large PPC relatively have obtained. In this paper, we have observed that PPC effect depends on temperature and exposure time. On the basis of the experimental results, we discuss the existing models.

변압기 보호를 위한 Fuzzy Decision Making 알고리즘

강대훈,이승재,강상희,권태원 明知大學校 産業技術硏究所 1999 産業技術硏究所論文集 Vol.18 No.-

This paper presents a new fuzzy decision making algorithm for power transformer protection based on the Dempster-Shafer's theory of evidence. To distinguish internal faults from other transient states, four input variables are selected. Each time dependent fuzzy rule base is composed of twelve fuzzy if-then rules associated with their basic probability assignments (BPAs) for singleton - or compound-support hypotheses. Dempsters rule of combination is used to process the fuzzy rules and get the final decision. The proposed algorithm also has a capability to identify the inrush, over-excitation and external fault with current transformer (CT) saturation besides the internal fault.

기술변화의 장기 특성 파악을 위한 반모수·접근분석에 대한 이론적 고찰

강승원,김배성 우송대학교 부설 산업연구원 1999 산업연구 Vol.1 No.2

The Study in the characteristics of technical structure of production and technical change have been prevailed in production analylsis. Most of existing studies on this subject mainly used the translog production function and gernerailzed Leontief production function, which are based on parametric methodology. However, if there is a possibility to be different between the true function and the pre-specified functional form, then the analysis based on the pre-specified function might be false. In the study, we apply semi-nonparametric technology to estimate the long-run technical change. We survey the various nonparametric studies, such as Chavas and Cox method and try to find an alternative methodology, Which is called semi-nonparametric approach.

보편적 서비스 제공을 위한 비용산정 모형연구

강승원 우송대학교 1999 우송대학교 논문집 Vol.4 No.-

Calculating costs for efficient universal service provision should be based on the long run incrementral cost methodology, which measures the increment in cost caused by identifiable elements that are needed in the production of a telecommunication service. In the long run increment cost models cost are traced and allocated on the basis of the activities performed for the products and services produced. Although calculating cost for universal service provision should be based on the long run incremental cost methodology, there is no discussion about long run incremental cost models in Korea. Cost models reduce the complex process of producing telecommunication service to a manageable numger of essential cost-determining relationships between factors of production and the service offer. There are a numger of cost models for universal service, which apply the long run incremental cost concept. Among them are Botton-up , Top-down, Hatfield, Benchmark Cost Proxy, Hybird Cost Proxy Models. In this paper, I investigate the various long run incremental cost models. To get the appropriate model which could be applied to korean telecommunication markets, I evaluate the cost models and get economic implications.