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      • SCOPUSKCI등재

        십이지장 제2부에 전이된 자궁경부암 1예

        이화영,손희정,이규택,김재준,백승운,이종균,이준혁,고광철,이풍렬,이종철,손정일,서연림,전성국 대한소화기내시경학회 1997 Clinical Endoscopy Vol.17 No.1

        In Korea, careinoma of the cervix is the most common malignancy in women annually affecting 25 per every 100,000 female. The widespread use of the Papanicolaou smear has resulted in earlier detection of the tumor and a reduction in the number of patients with advanced disease, but the incidence of cervix. carcinoma is still the fifth most common malignancy in the world. Cervical carcinoma spreads to the small bowel primarily by direct extension from involved lymph nodes, most commonly from peraaortic or mesenteric nodes to the serosa of the bowel. But, the involvement of small bowel by cervical carcinoma is so rare, and shows a maximum incidence of small bowel involvement of less than 1.5%. We report a patient with squamous cell carcinoma of the cervix metastases to the second portion of the duodenum in whom the diagnosis was made by endoscopic biopsy of the lesion.

      • SCOPUSKCI등재

        조직학적으로 진단된 담낭용종의 임상적 특징

        이석호,최윤호,손희정,류광현,이규택,김재준,김용일,최규완,최성호,백승운,이종균,고광철,이풍렬,이종철,노재형,이준혁,심상군 대한소화기학회 1999 대한소화기학회지 Vol.34 No.1

        Background/Aims: We aimed to clarify clinical factors which suggest the possibility of neoplastic polyps of gallbladder. Methods: Ninety-five resected gallbladders with polyps were included. Size and number of the polyps were obtained by preoperative ultrasonography. Histollogically, the polyps were classified into non-neoplastic (cholesterol and inflammatory or hyperplastic polyp) and neoplastic lesions (adenoma and adenocarcinoma). Clinical features, maximum diameter and number of the polyps were compared between the two groups. Results: Of 95 patients, non-neoplastic polyps were observed in 65.3% and neoplastic polyps were observed in 34.7%. We found cholesterol polyp in 47.4%, inflammatory or hyperplastic polyp in 17.9%, adenoma in 25.2% and adenocarcinoma in 9.5%. Two groups showed no difference in age, sex, body mass index, cholesterol, triglyceride, glucose, ALT, HBsAg carriage and the number of polyps. Among the patients with non-neoplastic polyps, 70.2% was under 60 years, while 72.7% of the patients with neoplastic polyps was over 60 years (p$lt;0.05). The size of polyps was under 10 mm in 88.9% of non-neoplastic polyps, and between 10 and 15 mm in 40% of neoplastic leisions. Moreover, 68.4% of neoplastic polyps exceeds 15 mm in diameter (p$lt;0.05). Conclusions: The size of polyp (≥10 mm) and patient's age (≥60 years) could be indicators for neoplastic polyps.

      • KCI등재

        중이염 후에 발병된 결절성 다발성 동맥염

        정성모 ( Seong Mo Jeong ),강풍 ( Poong Kang ),최효진 ( Hyo Jin Choi ),옥경선 ( Kyung Sun Ok ),박두관 ( Doo Kwan Park ),주미 ( Mee Joo ),한성훈 ( Seong Hoon Han ),이윤우 ( Yun Woo Lee ),이찬희 ( Chan Hee Lee ) 대한류마티스학회 2002 대한류마티스학회지 Vol.9 No.4

        Polyarteritis nodosa (PAN) is a disease of small and medium sized muscular arteries, typically involving the skin, kidney, peripheral nerves, muscle and gut. Although its etiology has not been known clearly yet, an immune complex is believed to initiate a vasculitis. Infections, such as hepatitis B virus, hepatitis C virus, and streptococcal infection, may be related with the development of PAN. We experienced a case of PAN preceded by Methicillin resistant staphylococcus aureus-associated otitis media in a 50-year-old woman. This is the first case reported in Korea.

      • SCOPUSKCI등재

        건강 검진자에서 담석의 유병률 및 위험요소

        이종균(Jong Kyun Lee),이풍렬(Poong Lyul Rhee),이준혁(Joon Hyeok Lee),이규택(Kyu Taek Lee),최성호(Seong Ho Choi),노재형(Jae Hyung Noh),김재준(Jae Jun Kim),고광철(Kwang Cheol Ko),백승운(Seung Woon Paik),이종철(Jong Chul Rhee) 대한소화기학회 1997 대한소화기학회지 Vol.29 No.1

        N/A Backgroud/Aims: For many years, it has been thought that gallstone disease was relatively rare and pigment stone was prevalent in Korea. But a few recent studies showed that 60-70% of gallbladder stones in Korea were cholesterol stone. This study was designed to obtain a prevalence and risk factors for gallstone in Korea. Methods: A total of 5,126 persons undergoing routine health screening enrolled in this study. All persons were given a questionnaire about smoking habits, alcoho] consumption, parity, and present illness along with its history of management. Height and body weight were checked. They were examined using ultrasonography and hiochemical test such as lipid profiles and fasting blood glucose. Gallstone disease was defined as the presence of posteriorly shadowing, echogenic, movable structures within the gallbladder as determined by ultrasonography and a history of previous cholecystectomy due to gallstones. Chi-square test and stepwise logistic regression analysis assessed the risk factors for gallstone disease. Results: The prevalence of gallstone disease in Korean adults(above 20 years old) was 4.7% in men and 5.2% in women. The age-standardized prevalence was 3.1% and 3.4% respectively. Gallstone disease was more frequent in the older age groups(6.6% in the sixth decade, 12.2% in the seventh decade, and 20.4% in the eighth decade). Age, obesity, hypertriglyceridemia, and diabetes were risk factors for gallstone disease. Smoking, alcohol consumption, parity, and hypercholesterolemia including LDL-C did not differ significantly between persons with and without gallstone disease. Conclusions: The prevalence of gallstone in Korean adults are 3.1% in men and 3.4% in women. The risk factors for gallstone are age, obesity, hypertriglyceridemia, and diabetes. Further studies will be needed about the prevalence of gallstone disease in general population according to the composition of gallstone.(Korean J Gastroenterol 1997; 29:85-92)

      • KCI등재

        Guidelines for the Diagnosis and Treatment of Chronic Functional Constipation in Korea, 2015 Revised Edition

        ( Jeong Eun Shin ),( Hye-kyung Jung ),( Tae Hee Lee ),( Yunju Jo ),( Hyuk Lee ),( Kyung Ho Song ),( Sung Noh Hong ),( Hyun Chul Lim ),( Soon Jin Lee ),( Soon Sup Chung ),( Joon Seong Lee ),( Poong-lyu 대한소화기기능성질환·운동학회(구 대한소화관운동학회) 2016 Journal of Neurogastroenterology and Motility (JNM Vol.22 No.3

        The Korean Society of Neurogastroenterology and Motility first published guidelines for chronic constipation in 2005 and was updated in 2011. Although the guidelines were updated using evidence-based process, they lacked multidisciplinary participation and did not include a diagnostic approach for chronic constipation. This article includes guidelines for diagnosis and treatment of chronic constipation to realistically fit the situation in Korea and to be applicable to clinical practice. The guideline development was based upon the adaptation method because research evidence was limited in Korea, and an organized multidisciplinary group carried out systematical literature review and series of evidence-based evaluations. Six guidelines were selected using the Appraisal of Guidelines for Research & Evaluation (AGREE) II process. A total 37 recommendations were adopted, including 4 concerning the definition and risk factors of chronic constipation, 8 regarding diagnoses, and 25 regarding treatments. The guidelines are intended to help primary physicians and general health professionals in clinical practice in Korea, to provide the principles of medical treatment to medical students, residents, and other healthcare professionals, and to help patients for choosing medical services based on the information. These guidelines will be updated and revised periodically to reflect new diagnostic and therapeutic methods. (J Neurogastroenterol Motil 2016;22:383-411)

      • SCIESCOPUSKCI등재
      • SCIESCOPUSKCI등재

        Conceptual Design of a Remote Monitoring and Control System for Nuclear Power Plants

        Lee Seung Jun,Kim Jong Hyun,Seong Poong Hyun Korean Nuclear Society 2003 Nuclear Engineering and Technology Vol.35 No.3

        Nuclear power plants (NPPs) will be highly connected network enabled systems in the future. Using the network and web enabled tools, NPPs will be remotely monitored by operators at any time from any place connected to the network via a general web browser. However, there will be two major issues associated with this implementation. The first is the security issue. Only the authorized persons need to be allowed to access the plant since NPP is a safety-critical system. However, the web technology is open to the public. The second is the network disturbance issue. If operators can not access the plant due to network disturbances, the plant will come into the out-of-control situation. Therefore, in this work, we performed a conceptual design of a web-based remote monitoring and control system (RMCS) considering these issues.

      • SCISCIESCOPUS

        Autonomous operation algorithm for safety systems of nuclear power plants by using long-short term memory and function-based hierarchical framework

        Lee, Daeil,Seong, Poong Hyun,Kim, Jonghyun Elsevier 2018 Annals of nuclear energy Vol.119 No.-

        <P><B>Abstract</B></P> <P>With the improvement of computer performance and the emergence of cutting-edge artificial intelligence (AI) algorithms, an autonomous operation based on AI is being applied to many industries. An autonomous algorithm is a higher-level concept than conventional automatic operation in nuclear power plants (NPPs). In order to achieve autonomous operation, the autonomous algorithm needs to include superior functions to monitor, control and diagnose automated subsystems. This study suggests an autonomous operation algorithm for NPP safety systems using a function-based hierarchical framework (FHF) and a long short-term memory (LSTM). The FHF hierarchically models the safety goals, functions, systems, and components in the NPP. Then, the hierarchical structure is transformed into an LSTM network that is an evolutionary version of a recurrent neural network. This approach is applied to a reference NPP, a Westinghouse 930 MWe, three-loop pressurized water reactor. This LSTM network has been trained and validated using a compact nuclear simulator.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Autonomous control algorithm for safety functions was modeled with a FHF and an LSTM. </LI> <LI> LSTM network was trained using a simulator and validated to demonstrate the effectiveness of the algorithm. </LI> <LI> Autonomous control could manage the plant safety better than the current automation plus human control. </LI> </UL> </P>

      • SCISCIESCOPUS

        Development of a quantitative method for evaluating the efficacy of cyber security controls in NPPs based on intrusion tolerant concept

        Lee, Chanyoung,Yim, Ho Bin,Seong, Poong Hyun Elsevier 2018 Annals of nuclear energy Vol.112 No.-

        <P><B>Abstract</B></P> <P>Many regulatory documents, guides, and standards for cyber security issues in the nuclear industry have been published since Digital Instrumentation and Control (DI&C) systems were introduced to Nuclear Power Plants (NPPs). However, there are still difficulties when it comes to deciding which security controls are needed and to defining appropriate security control requirements for NPPs. With these regard, a quantitative method for evaluating the efficacy of security controls for DI&C systems in NPPs based on the intrusion tolerant concept is proposed in this study. The essence of the suggested method, <B> <I>In</I> </B>trusion <B> <I>To</I> </B>lerance based <B> <I>C</I> </B>yber <B> <I>S</I> </B>ecurity <B> <I>I</I> </B>ndex (<I>InTo-CSI</I>), is defined as a reduction ratio of probability that a cyber-attack damages a target system. The intrusion tolerant concept is applied to the evaluation method because availability of system’s safety functions is the first priority in the nuclear industry. “How much the system is intrusion-tolerant” means that to what extent does the system provide the minimum level of safe operation when facing unexpected intrusions. Based on intrusion tolerant strategies, an event tree was constructed, and <I>InTo-CSI</I> was estimated by failure probability of intrusion tolerant strategies: the resistance strategy, the detection strategy, and the graceful-degradation strategy. Among these three strategies, quantifying failure probability of the resistance strategy is more challenging than the other two strategies because its relation with attack-difficulty. Attack-difficulty has a strong dependence on unexpected and abstract factors such as attacker’s skills and accessibility to information of the target system. For this reason, the model of Mean Time To Compromise (MTTC) was adopted to estimate abstract variables, and the adopted model was revised in accordance with the suggested evaluation method. Validity of the suggested method was proven by conducting a case study. The suggested method can help assess how much the system security can be improved by applying specific cyber security controls, and which types of additional cyber security controls should be taken. Furthermore, <I>InTo-CSI</I> can make security designers achieve efficacy levels of the specific target system by quantitatively evaluating cyber security controls.</P> <P><B>Highlights</B></P> <P> <UL> <LI> A quantitative index was developed to evaluate the efficacy of security controls in NPPs. </LI> <LI> The intrusion tolerant concept was applied to the evaluation method. </LI> <LI> The model of Mean Time To Compromise (MTTC) was adopted to estimate abstract variables. </LI> <LI> The adopted model and concept were revised in accordance with the suggested method. </LI> <LI> The validity of the suggested method was demonstrated by conducting a case study. </LI> </UL> </P>

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