주의력 결핍 과잉행동장애 아동의 평가를 위한 정지신호 과제의 적용

시현석,이종범,박형배,사공정규,송창진,배진우 大韓神經精神醫學會 2000 신경정신의학 Vol.39 No.1

연구목적 및 방법 : ADHD환아에 있어 뇌의 전두엽의 기능인 실행기능 중 특히 억제기능을 가장 잘 측정하는 것으로 알려진 정지신호과제를 사용하여 실제로 정지신호를 ADHD환아에게 적용하였을 때 정상 아동과 비교하였을 때 ADHD의 전두엽의 실행기능 중 억제 기능의 이상을 실질적으로 반영하는 검사인지, 증상의 정도와 수행결과는 어떤 연관성을 보이는지, 현재 가장 널리 사용되고 있는 연속수행 검사와는 어떤 차이를 보이는지, 과잉행동의 유무와 수행의 연관성은 어떠한지 그리고 부가적으로 정지신호과제의 ADHD진단에 있어서의 판별력은 어느 정도인지를 알아보기 위해 본 연구를 시행하였다. 전두엽의 기능을 반영하는지와 임상에서의 유용성을 알아보기 위해 ADHD군 40명과 대조군 18명을 대상으로 연구하여 다음과 같은 결과를 얻었다. 결 과 : 대조군과 ADHD군의 비교에서는 정지신호과제의 수행 성적은 상대적 종결속도의 Z점수(ZRFT)와 블록당 평균 지연시간(mean delay×block), 그리고 일차 반응시간(primary-RT)에 있어서 유의한 차이가 있는 것으로 나타났다(p<0.05), ADHD군과 대조군의 연속수행검사(CPT)의 수행에 있어 유의한 차이가 나는 변인은 없었다. 또한 두 검사간의 상관성에 있어서는 정지신호반응시간(SSRT)와 CPT의 정반응시간이 그리고 primary-RT와 일차반응시간의 표준 편차(primary-SD)가 CPT의 민감도와 정반응시간과 상관성이 있는 것으로 나타났다(p<0.05). 정지신호과제 수행과 한국형 주의력결핍 장애 평가 척도 - 가정판(ADDES-HV)과의 상관도에서는 유의한 상관성을 나타낸 것은 없었다. 나이와 지능에 따른 정지신호과제의 경향분석에서 유의하게 경향성을 나타낸 것은 지에 따른 차이에서는 primary-SD였으며 나이에 따른 차이에서는 SSRT였다(p<0.05). 여기에서 지능과 primary-SD와의 관계는 지능이 증가함에 따라 감소하다 어느 정도에서 더 이상 감소하지 않았으며, 나이와 정지신호반응시간과의 관계는 나이가 증가함에 따라 반응시간이 짧아지다가 어느 정도에서 더 이상 감소하지 않는 추세를 보였다. 정지신호과제의 판별력 검증에서 mean delay×block과 primary-RT가 가장 높은 판별력(각각 75%)을 나타냈으며 그 외 억제율(P-inhibit)은 63.89%, SSRT는 58%, ZRFT는 67%, primary-SD는 58%의 판별력을 보였다. ADDH 환아를 대상으로 과잉행동이 있는 군과 없는 군으로 나누어 수행의 정도를 비교하였다. 여기에서는 두 군 사이에 유의한 차이가 있는 변인은 없었다. 결 론 : 이러한 결과로 볼 때 정지신호과제가 국내에서 사용된다면 향후 임상에서의 ADHD의 선별검사로서 뿐만 아니라 연구에 있어서도 기여하는 바가 크다고 생각된다. Objectives and Methods : The purpose of this study was to examine availabilities of stop-signal task as a screening test for ADHD and as a research tool. Stop-signal task was applied to 40 ADHD patients and 18 normal children. Followings are the results of this study. Results : There were significant differences between ADHD group and control group in ZRFT, mean delay×block and primary-RT of stop-signal task performance(p<0.05). There was no significant difference in results of continuous performance test. SSRT of stop-signal task had significant correlation with hit reaction time of continuous performance test, and primary-RT and primary-SD with attentiveness and hit reaction time of continuous performance test. There was no significant correlation between scores of ADDES-HV and stop-signal task performance. In change of primary-SD according to intelligence, primary-SD decreased as intelligence increased but made plateau after IQ 110, and in change of SSRT according to age, SSRT decreased as intelligence increased but made plateau after 10 year-old. In discriminant ability, mean delay×block and primary-RT showed highest discriminant ability(each 75%). In addition P-inhibit showed 63.89%, SSRT showed 58%, ZRFT showed 67%, and primary-SD showed 58% in discriminant ability. There was no significant difference in stop-signal task performance between ADHD with hyperactivity and ADHD without hyperactivity. Conclusions : In this point of view, stop-signal task was proved to be useful research tool for attention deficit hyperactivity disorder as well as useful screening test tool.

出産進度에 영향을 주는 要因分析 : Longitudinal Approach

韓聖鉉,李時伯 家族計劃硏究院 1977 家族 計劃 論集 Vol.4 No.-

콘크리트 바닥판 연속타설에 따른 강상자형교의 거동

구현서,정경섭,정해근,김경남 충북대학교 건설기술연구소 2002 建設技術論文集 Vol.21 No.1

The superstructures of the steel box bridge, which support the vehicle load directly, are composed of two main components; the steel box and the concrete slab, which are designed as a compositely behaving structure. In the composite girder bridges, the concrete pouring procedures cause different bending moments at each location of a girder. The difference in bending moment is also caused by the varied stiffness of the girders. For the open section type of steel girders which is used in many countries, the sequential concrete pouring method is suggested on the basis of the influential lines concept in order to minimize the effect of such moments. However, the effect is insignificant for the closed section steel box girders which are mostly used in Korea. This paper deals with the behavior of closed section steel girder box bridge according to the continuous pouring concrete slab. Both experimental and structural analysis were performed to assess the behavior of the composite steel box girder bridge under construction.

우리나라 사망구조의 지역별 차이에 관한 연구

한소현,이시백 서울大學校 保健大學院 2001 보건학논집 Vol.38 No.1

It is recognized that decreased mortality increasing the length of human life has been the major factor in acceleration of population increase. Therefore, death remains a subject of deep concern not only to the person but also government at all levels. The purpose of this present study is to measure the differences in death rates of region which persist the general reduction in mortality. The data for the present study of trend in differential mortality by region were derived from the official mortality statistic of Korea from 1980 to 1999. Mortality differentials were calculated for male and female by geographic region using age-adjusted death rates. It is apparent that there were considerable differences in age-adjusted death rates by region. Mortality was higher in Jeonam and Kyungbuk provinces for each sex than kyung-gi province and city area.

흰쥐 호흡기도내에서 혈소판활성인자에 의한 모세혈관 투과성의 증가시 Nitric Oxide Synthase Inhibitor의 효과

김천규,전시영,김진평,김현성,강재용,황의기 대한이비인후과학회 2000 대한이비인후과학회지 두경부외과학 Vol.43 No.2

국내 생산 재생골재의 품질수준 평가

전명훈,이세현,이성복,이도헌 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1(구조계)

Recycling waste concrete is very important for environmental pollution prevention, overcome aggregates shortage and effective use of resource. The examples of using recycled aggregates such as ground backfill, road construction, concrete production. But, aggregate for structural concrete requires high degree of quality. We investigated the quality of domestic recycled aggregates in order to activate the use of recycled aggregates to seek the technologically, politically supplement factors to contribute to the effective use of recycled aggregates which has ever been a national problem, and which would solve the aggregates shortage.

싸이클론의 건식 공정으로 생산된 재생 잔골재를 사용한 콘크리트의 중성화 저항성 및 건조수축에 관한 실험적 연구

김병윤,이세현,서치호 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1(구조계)

The purpose of this study was to provide durability data of concrete using recycled fined aggregate which was produced through a dry production with cyclone for making it sure whether it can be put to practical use for concrete. In the experiment. recycled fine aggregate was substitute for natural fine aggregate the rate of 0, 25, 50, 75 and 100% each. The results of the study were as follows; 1. The depth of neutralization was become deeper according to the increase of substitutive ratio of recycled fine aggregate. 2. The performance of length alternation was fallen gradually according to the increase of substitutive ratio of recycled fine aggregate. But, it showed the similar durability with concrete using natural fine aggregate fewer than 25% substitution ratio. Based on the above results, it is concluded that the recycled fine aggregate through the wet production process can be used as fine aggregate on condition that the substitution ration is under 25%.

표면개질 실리카막을 이용한 CO_2 선택투과분리

김성수,최현교,박홍채,김태옥,서봉국 한국환경과학회 2000 한국환경과학회지 Vol.9 No.4

To improve CO_2 permselectivity, a modified silica membrane was prepared by chemical vapor deposition with tetraethoxysilane(TEOS)-ethanol-water, and TEOS-ethanol-water-HCI solution at 300-600℃. The silica was effectively deposited in the mesopores of a γ-alumina film coated on a porous α-alumina tube by evacuating the reactants through the porous wall. In this membrane, CO_2 interacts, to some extent, with the pore wall, and CO_2/N_2 selectivity then exceeds the value of the Knudsen diffusion mechanism, while the membrane derived from TEOS alone has no CO_2 selectivity. The silica membrane prepared from TEOS-ethanol-water-HC1 solution showed that CO_2 permeance was 2.5×10 exp (-7)㏖/s^-1. m^-2. Pa^-1 at 30℃ and CO_2/N_2 selectivity was approximately 3. The CO_2 permeance and selectivity was improved by enlarging the surface diffusion with modification of chemical affinity of the silica pores.

플라이애쉬와 제지애쉬를 혼합 사용한 모르타르의 특성에 관한 실험적 연구

송태협,이세현,서치호 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1(구조계)

The fly ash has been widely used in the latest to complement the physical performance and economical efficiency of the concrete which uses only a normal porland cement. The paper ash gained through the incineration of paper sludge is possible to be used as the material of concrete because it contains the properties similar to the previous fly ash in ingredients and physical characteristics. Therefore, this research has tested the physical characteristics by replacing 20 % of fly ash used with the paper ash to solve the problem which lowers the early strength caused when the fly ash was used. As a result, it showed that the fluidity becomes lower and the compression strength becomes increased by using paper ash. In addition, after mixing the paper ash with the fly ash, it showed that the time and heating amount of the 2nd peak of the minor heat of hydration affecting the revelation of strength was equivalent to the combination for normal portland cement, and also indicated that the compression strength for 3 days is superior to the combination of the fly ash. Therefore, if the paper ash having a regular fineness is used, it was effective in improving the early strength of concrete used the fly ash.

통계적 방법을 이용한 오존 형성의 예측

여영구,손상현,오세천 漢陽大學校 環境工學硏究所 1999 環境科學論文集 Vol.20 No.-

통계적 방법을 이용하여 오존 형성의 예측에 관한 연구를 수행하였다. 통계적 방법으로는 파라미터 평가 방법과 인공신경 회로망 방법이 적용되었다. 파라미터 평가 방법에는 실시간 파라미터를 평가하기 위하여 ELS 및 RML 방법이 사용되었으며 오존 형성의 모델로는 ARMAX 모델을 사용하였다. 또한 3층 구조를 갖는 인공신경 회로망 방법을 이용하여 오존 형성의 예측 시험을 수행하였으며 본 연구에 사용된 통계적 방법의 성능을 평가하기 위하여 오존 형성의 예측결과를 실제자료와 비교 분석을 하였다. 실제 자료와의 비교를 통하여 파라미터 평가 방법 및 인공신경 회로망 방법에 근거한 예측방법이 제한된 예측 구간 내에서 만족할 만한 성능을 보임을 확인할 수 있었다. The prediction of ozone formation was studied using the stochastic method, Parameter estimation method and artificial neural network(ANN) method were employed in the stochastic scheme. In the parameter estimation method, extended least squares(ELS) method and recursive maximum likelihood(RML) were used to achieve the real time parameter estimation. Autoregressive moving average model with external input(ARMAX)was used as the ozone formation model for the parameter estimation method, ANN with 3 layers was also tested to predict the ozone formation. To demonstrate the performance of the ozone formation prediction schemes used in this work, the prediction results of ozone formation were compared to the real data. From the comparison it was found that the prediction schemes based on the parameter estimation method and ANN method show an acceptable accuracy with limited prediction horizon.