은이온 선택성 막전극의 제조와 특성에 관한 연구

권수한,이심성,김재상 慶尙大學校 기초과학연구소 1986 基礎科學硏究所報 Vol.2 No.-

It was found that silver ion selective electrode prepared by mixing AgI with PVC by the ratio of 5:1 was hard and durable. The response potentials of this electrode were reproducible and linear within 10^-1∼10^-7M of Ag(Ⅰ) ion concentration and its slope was 62.2㎷ per decade concentration at 298K. This electrode did not show significant response to the other cations except silver ion, but had good response to iodide, chloride, bromide and cyanide anions within 10^-1∼10^-5M. It was also found that the potentials of this electrode had not been influenced to pH in range of 1.0-8.0. This electrode could be used as an indicator electrode in potentiometric titration of single halide ion and also halide mixture with standard solution of silver nitrate.

주의력 결핍 과잉행동 장애 아동에서의 집단 프로그램의 치료 효과

심세훈,오창근,권자영,정유숙,홍성도 순천향의학연구소 2003 Journal of Soonchunhyang Medical Science Vol.9 No.1

Background : The authors attempted to introduce group program for improving interpersonal relationship and evaluate the effects of that program. Material and Methods : This program had been held twice a week for 8 weeks for children and parents training had been for times on the treatment and continued from 2001 to 2002. Twenty-five ADHD children in school age were selected as subjects from child psychiatric clinic of a general hospital in Seoul. Treatment outcomes were evaluated by comparing at pre- and post- treatment using the various rating scale. Result : According to the results of statistical analysis, paired t-test, the score of total self-concept including popularity was increased and family environment and parenting stress were improved significantly. These results suggest that this program is useful for its orginal goal. The parents evaluated also that children's total problem behaviors were decreased. Conclusion : These results suggest that the designed and performed group program in this study would be effective in facilitating ADHD children's emotional and interpersonal growth, and decreasing their parents stress. Finally they would have healthy interpersonal reationship.

거친 표면을 가진 흡수체와 버퍼의 측면에 의한 극자외선 산란효과

권영근,심상진,김종회,김옥경,오혜근 한양대학교 이학기술연구소 2003 이학기술연구지 Vol.6 No.-

마스크 상의 거친 표면을 정의하기 위해서 Monte-Carlo 방법이 적용되었다. 극자외선 마스크의 거친 표면 함수, 즉 power spectral density 에 의해 표현된 무작위적인 표면의 높이 변화는 상면에서의 전기장을 계산하기 위해서 재정의 되었다. Feynmann의 접근 방식과 유사한 산란에 대한 일반식을 유도하였고, 이는 결상과정에서 마스크의 단차상의 거친 측면에 의한 효과를 알아보기 위해서 적용되어졌다. 거친 표면과 완전히 편평한 표면에 대한 전기장의 위상과 진폭 변화 정도를 비교하기 위해서 다중 산람 문제 또한 여러 다른 패턴에 대하여 이 논문에서 다뤄졌다. The Monte-Carlo Method is adopted to define the roughness of the mask structure. A random surface height variation described by power spectral density for the rough surfaces of an estreme ultraviolet (EUV) mask is to be redefined to calculate the field in the image plane. A general explicit formula of the scattering, which is analogous to Feynman's approach, is derived, and it is adapted to the EUV mask structure to evaluate the effect of the surface roughness of the side wall of the mask topography on the image formation. The multiple random scattering problems are dealt with the different pattern types in order to compare field variations in phase and amplitude with the ideal flat surface.

Xenotime중의 희토류 산화물 분리방법에 관한 연구

심상권,김경림,박해경 연세대학교 산업기술연구소 1990 논문집 Vol.22 No.2

This study is concerned with the separation method of total rare earth oxides in Xenotime by acid digest method. Thioacetamide was used as a carrier, tartaric acid was used as a masking agent and oxalic acid was used as a precipitant. So the effects of three acid digest methods, pH of the solution, digesting time, tartaric acid, oxalic acid and aging time were oberved. The results showed that the best acid digest method was sulfuric acid leaching and mixed acid digest method, and that pH of the solution was 2, digesting time was 4 hours, tartaric acid was 100ml of 2% solution, oxalic acid was 8gr. and aging time was 1 hour. Through this experiment, it was confirmed by X-ray diffractometer that the separated total rare earth oxides consisted of the Yttrium and the other rare earth elements ; Gadolinium, Dysprosium, Erbium, Ytterbium and trace rare earth elements. The pure rare earth oxides being separated by this method were dried and ignited at 900℃.

Clinical Significance of Tissue Levels of Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases in Gastric Cancer

심기남,정성애,주양희,유권 이화여자대학교 의과대학 2005 EMJ (Ewha medical journal) Vol.28 No.2

목적: 본 연구는 암의 침윤과 전이에 필수적인 기질단백분해효소(matrix metalloproteinases, MMPs)와 억제인자(tissue inhibitor of metalloproteinase, TIMPs)의 발현정도를 위암의 생검조직에서 확인하고 임상적, 병리학적 소견과의 상관관계를 분석하여 임상적 유용성을 평가하고자 하였다. 방법: 2003년 8월부터 2004년 7월까지 본원에서 위암으로 진단되어 근치적 치료를 받은 30명의 환자를 대상으로 하였다. 조직은 위내시경 검사시 정상 점막 및 암으로 진단한 병변에서 생검겸자를 이용하여 얻었다. 역전사중합효소연쇄반응(RT-PCR)을 이용하여, 정상조직을 기준으로 암조직에서의 MMP-W, MMP-9, MT1-MMP, TIMP-1, TIMP-2의 발현정도를 반정량법으로 비교하였다. 결과: MT1-MMP의 발현정도는 위암의 분화도, 림프혈관계 침윤, 림프절 전이 및 암의 병기와 유의한 상관관계가 있었다.(p<0.05). 그 외의 MMP-2, MMP-9, TIMP-1,TIMP-2의 발현은 임상적 소견과 유의한 관계를 보이지않았다. 결론: 반정량적 역전사중합효소연쇄반응을 이용하여 MT1-MMP의 발현 증가 유무를 확인하는 것은 위암의 공격적 특성을 예측하는데 유용할 것으로 생각되며, 이러한 검사는 수술 전에 얻어진 생검조직을 이용하여 가능하므로 암의 공격성에대한 정보를 수술 전에제공할 수 있을 것으로 사료된다.

고등급 이형성을 보인 편평톱니샘종

권경주,정성애,심기남,정정화,강석형,송도경,전승정,김혜인 이화여자대학교 의과학연구소 2012 EMJ (Ewha medical journal) Vol.35 No.1

Until recently, colorectal polyps were classified predominantly as hyperplastic or adenomatous. While adenomatous polyps are well-characterized precursor lesions of adenocarcinomas, hyperplastic polyps have been considered as benign lesion. However, some hyperplastic polyps with serrated morphology of the crypts have been recognized to have distinctive features and these polyps were termed ‘serrated adenomas’. Recent data show that sessile serrated adenomas (SSA) might be the precursors of serrated colonic cancers, underlining the necessity of identifying them. SSA is approximately 3% of all polyps, commonly appears as flat or sessile and yellowish due to mucus production. In the pathogenesis of SSA, progression to high grade dysplasia or early invasive carcinoma may be associated with serrated neoplasia pathway different from adenoma-carcinoma sequence. We report a case with a colon polyp diagnosed as sessile serrated adenoma with high grade dysplasia after endoscopic submucosal dissection.

위암종과 Epstein-Barr 바이러스와의 연관성에 대한 연구

심광용,김호영,김효열,백순구,권상옥,조미연,이창훈,이종인 건국대학교 의과학연구소 2004 건국의과학학술지 Vol.14 No.-

Objectives: Epstein-Barr virus (EBV) has been known to be linked to a spectrum of neoplastic conditions, including nasopharyngeal carcinoma, Burkitt's lymphoma, peripheral T-cell lymphoma and Hodgkin's disease. This study aims to investigate the association of EBV with gastric carcinoma in Korea. Methods: Fifty-three cases of gastric adenocarcinoma were studied for evidence of EBV infection by EBV-encoded small RNA (EBER) in situ hybridization (ISH) on the paraffin sections and amplifying the EBV genome encoding envelop glycoprotein (gp220) with polymerase chain reaction (PCR) in fresh gastric cancer specimens. Results: EBER was detected in 7 (13.2%) of 53 gastric carcinomas and all cases were male. In 6 (85.7%) of 7 EBER-positive cases, the tumors were located in the upper and middle part of the stomach. EBER ISH study showed strong positivity in all the tumor cells, but negativity in surrouning lymphocytes, stromal cells and normal gastric mucosa. DNA PCR was positive in 23 (43.4%) of 53 gastric carcinomas, including all of 7 EBER-positive cases. Conclusion: We could observe some association of EBV with gastric carcinoma, and our findings about the charateristics of EBV-positive gastric cancers involving sex, site and histological type are similar to those in Japan. However, EBV-positive rate of gastric cancer is higher than in Japan and lower than in Western countries. Further studies to elucidate oncogenic mechanism of EBV in gastric cancer should be performed.

건설현장 근로자들의 안저예방실태와 사고예방과의 개선요인 조사연구

심규범,남철현,최상복,이송권,이정희,이순자,문기내,김문환 慶山大學校 保健福祉硏究所 2003 保健福祉硏究 Vol.8 No.-

This study was conducted to examine aspects of health and safety education and demand level of safety education in construction job sites in order to provide direction of safety education development. The subjects of this study were 566 workers who were working in construction job sites located in Daegu City and Kyungbuk Province. Data were collected from June 1, 2002 to August 30, 2002. The results of this study can be summarized as follows. 1. According to safety education by experience methods, the proportion of education by lecture was highest (90.6%). The proportion of education by field practice was 13.1%. 2. Among the education methods which they thought as the most desirable method, the proportion of audio-visual education was 39.4% and the proportion of education by experience was 37.5%. Those who had more monthly income and higher education level preferred audio-visual education, while those who were younger and less educated preferred education by experience. 3. In the case of the contents of the safety education which they thought as the most important one, the proportion of enhancement of safety awareness and education of risk factors was highest (24.7%). The groups of older workers, having longer working period, and belonging to higher education level preferred these contents. 4. According to the factors which were most important to increase effectiveness of the safety education were workers' voluntary participation (27.7%), 40 to 49 years old (27.7%), and monthly income of one million, five hundred thousand won to one million, nine hundred ninety thousand won (32.0%). The proportions of lower educated workers and working as daily workers were also high. 5. The variable which most influenced the safety education was age. The safety awareness of construction job sites was the second highest influential variable. From above results, it is clear that the workers' participation in the safety education was low since most of the safety educations were formal education by lecture. Although they participated in the education, the education was also not effective because they compulsorily participated in it. Therefore, it can be concluded that effective alternative policies must be formulated.

철의 원자흡수 분광법에서 세륨 및 이트륨의 해방효과

권수한,이심성,김재상 慶尙大學校 1985 論文集 Vol.24 No.2

In the atomic absorption spectrometry, the interferences of Ni, Co, and Cu on the iron absorption and the repression of this interference by the addition of cerium and yttrium have been studied. The interference by Ni, Co and Cu existed in the sample solution as the same amount as iron are completely released by the addition of cenium and yttrium twice as much as interfering cation. The intenference by the mixed interfering cations(Ni, Co, Cu) are larger than by each interfering cation and however the releasing of the interference by cerium and yttrium are effective up to some degree of the concentration of mixed interfering cations.

웹 기반 학습에서 개요제시방식이 학습장애아동의 학업성취에 미치는 영향

권성호,심영경 이화여자대학교 사범대학 교육과학연구소 2004 교육과학연구 Vol.35 No.1

학습내용에 대한 개요를 제시하는 방식은 학습자의 개인차 변인에 따라 달라져야 한다. 특히 주의집중에서의 문제를 보이는 학습장애아동들에게 있어 개요제시방식은 학습자에게 적합하고 학습자가 선호하는 형태일 때, 학습이 효과적으로 일어날 수 있기 때문에 중요하다. 이에 본 연구에서는 개요제시방식을 문자-위계적인 개요제시방식과 그림-위계적인 개요제시방식 두 가지로 선정하여 학습장애아동의 학업성취에 어떠한 영향을 미치는지 알아보고자 하였다. 연구 결과 길게 쓰여진 문자-위계적인 개요제시방식 보다 간단하게 나타난 그림-위계적인 개요제시방식으로 학습한 집단이 학업성취가 더 높게 나타났다. 웹 기반 학습에서 그림-위계적인 개요제시방식이 학습장애아동의 학업성취도를 높이는데 도움이 되는 이유는 학습장애아동의 학습에 대한 선택적 주의 집중능력과 부호화 능력 등 학습에 대한 자발적인 능력이 부족하기 때문에 나타나는 것임을 알 수 있었다. 따라서 자발적인 학습전략이 부족한 학습장애아동의 개요제시방식에 있어서 그림-위계적인 개요를 제시한다면 학업성취를 더 높일 수 있을 것이다. Overview presentation modes for studying contents must apply in different ways depending on the student characteristics. Especially in case of the student with learning disability who have difficulties in selective attention. The offer of learning sources according to the special learning character can inspire the learning desire and improve the effectiveness. In this study, I researched into the effect of proffer character-hierarchical overview presentation modes and imagery-hierarchical overview presentation modes on academic achievement of student with learning disability. The result of this study is as follows. Simple imagery-hierarchical overview presentation modes is much easier for them to understand than long character-hierarchical overview presentation modes. The reasons why the imagery-hierarchical overview presentation modes can help the students with learning disability to improve their academic achievements are as follows. The students with learning disability are poor at paying their attentions on the important concept selectively, less encoding ability to encode information voluntarily. Therefore, may improve more studies accomplishment if present imagery-hierarchical overview presentation for students with learning disability that voluntary studying strategy is lacking.