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프로젝트 기반학습을 활용한 상호문화교육 연구 -외국인학교 청소년 학습자를 중심으로-
주양희 ( Joo Yang Hee ) 서울대학교 국어교육과 2022 先淸語文 Vol.50 No.-
The purpose of this study is to design teaching and learning strategies for formulating balanced intercultural understanding ability and autonomous cultural identity in young adolescents at international schools. Culture lessons based on project-based learning (PBL) are comprised to understand the learners’ intercultural adjustment process and response. This study was aimed to suggest applicable teaching and learning strategies for intercultural education in the field of education. International schools consist of young adolescents Korean learners that lived abroad for more than 3 years or learners from multicultural families, and they are commonly referred to as Third Culture Kids (TCKs). TCKs naturally learn from their experience while living abroad. Considering their backgrounds, TCKs feel confused about their culture. Also, compared to their peer groups, their lack of knowledge on Korean culture causes an experience of culture shock and a confusion with their cultural identity. Their characteristics consist of having multicultural backgrounds as well as being bilingual. This creates a multicultural environment through interaction with the others who have different cultures. This study proposes that intercultural education method utilizing project-based learning lessons is suitable to support learners to search for cultural identity from other individual’s third culture. This results in forming learners that understand cultural diversity and independent attitude as intercultural practice. The subjects of this study are sixth and seventh-graders at an international school in Incheon. The study was conducted to design culture lessons based on PBL, presumed ideological culture, and practiced them gradually. Through the culture lessons based on PBL, the possibility in formation of learners’ autonomous cultural identity from a change of identity in the process of intercultural exchange were observed. However, learners failed to form independent attitude and identity formation due to the absence of cultural knowledge, passive attitude in cultural awareness adjustment, and difficulty in communication in the lingual aspect. Therefore, learners need an opportunity to actively discover and personalize the connection with their own life from authentic materials applied from cultural elements. This study was conducted with young adolescents at an international school to implement cultural PBL lessons. In the process of the implementing, reflecting, and adjusting the PBL lessons, the study suggests the educational methods with consideration of the learners’ unique characteristics. It is meaningful to seek the possibility of an education that can form an autonomous cultural identity as the third culture that the learners recognize the culture and find their cultural location as intercultural practice through the process of learning, reflection, and development with the interface between real life.
정하라,주양희 한국문화융합학회 2022 문화와 융합 Vol.44 No.8
The study aims to examine the academic experience of adult Korean learners in the digital space and derive the implications of Korean language education for them. In this study, it was intended to examine the motivation and academic performance of married migrant women to enter Korea National Open University. This study conducted a case study by collecting in-depth interview data of migrant women from China and Vietnam with diverse majors and learning trajectory as participants. Based on the collected data, the educational implications needed for adult learners to receive online higher education are as follows: first, close cooperation with related institutions to expand the influx of online higher education institutions; second, strengthening support for adaptation to the first semester after admission; third, promoting interaction among multicultural learners within the campus; and fourth, providing support needed for Korean language education focused on writing as basic learning capability support.
심기남,정성애,주양희,유권 이화여자대학교 의과대학 2005 EMJ (Ewha medical journal) Vol.28 No.2
목적: 본 연구는 암의 침윤과 전이에 필수적인 기질단백분해효소(matrix metalloproteinases, MMPs)와 억제인자(tissue inhibitor of metalloproteinase, TIMPs)의 발현정도를 위암의 생검조직에서 확인하고 임상적, 병리학적 소견과의 상관관계를 분석하여 임상적 유용성을 평가하고자 하였다. 방법: 2003년 8월부터 2004년 7월까지 본원에서 위암으로 진단되어 근치적 치료를 받은 30명의 환자를 대상으로 하였다. 조직은 위내시경 검사시 정상 점막 및 암으로 진단한 병변에서 생검겸자를 이용하여 얻었다. 역전사중합효소연쇄반응(RT-PCR)을 이용하여, 정상조직을 기준으로 암조직에서의 MMP-W, MMP-9, MT1-MMP, TIMP-1, TIMP-2의 발현정도를 반정량법으로 비교하였다. 결과: MT1-MMP의 발현정도는 위암의 분화도, 림프혈관계 침윤, 림프절 전이 및 암의 병기와 유의한 상관관계가 있었다.(p<0.05). 그 외의 MMP-2, MMP-9, TIMP-1,TIMP-2의 발현은 임상적 소견과 유의한 관계를 보이지않았다. 결론: 반정량적 역전사중합효소연쇄반응을 이용하여 MT1-MMP의 발현 증가 유무를 확인하는 것은 위암의 공격적 특성을 예측하는데 유용할 것으로 생각되며, 이러한 검사는 수술 전에 얻어진 생검조직을 이용하여 가능하므로 암의 공격성에대한 정보를 수술 전에제공할 수 있을 것으로 사료된다.
대장 선종과 대장암에서 MMP-2, HIF-1α 및 VEGF의 발현
신정은,정성애,김성은,주양희,심기남,김태헌,유권,문일환 대한소화기학회 2007 대한소화기학회지 Vol.50 No.1
Backround/Aims: This study was aimed to investigate the expression of matrix metalloproteinase-2 (MMP-2), hypoxia-inducible factor (HIF)-1α, and vascular endothelial growth factor (VEGF) in colonic adenoma-carcinoma sequence. Methods: Thirty-two tissue samples of colon adenoma, 11 of early colon cancer and 36 of advanced colon cancer were collected by colonoscopic biopsy. Normal colonic tissues were also collected from the same subjects. The mRNA expression levels of MMP-2, HIF-1α, and VEGF were quantitated using semiquantitative reverse transcription polymerase chain reactions. The protein expressions of activated MMP-2 and HIF-1α were examined by gelatin zymography and by Western blot in surgically resected cases, respectively. Results: The expression level of MMP-2 mRNA showed a progressive increase in the advance of the colorectal adenoma-carcinoma sequence (p<0.05). In colon cancer tissues, the expression level of MMP-2 mRNA showed an increasing trend according to differentiation, lymphatic invasion and Dukes' stage (p<0.05). The protein expression of activated MMP-2 was observed in 10 of 11 (91%) cases of cancer tissues. The mRNA expression levels of HIF-1α and VEGF were greater in tissues of early and advanced colon cancer compared with colon adenoma (p<0.05; p<0.001). The protein expression of HIF-1α was observed in 9 of 11 (82%) cases of cancer tissues. The mRNA expression level of HIF-1α showed a positive correlation with MMP-2 and VEGF, respectively (r=0.52, p<0.001; r=0.76, p<0.001). Conclusions: MMP-2, HIF-1α, and VEGF may be useful in detecting early carcinogenesis and progression of colon cancer. (Korean J Gastroenterol 2007;50:9-18) 목적: 대장암 발생 과정 중 초기 기저막 파괴에 관여하는 MMP-2와 신생혈관 형성에 관여하는 HIF-1α와 VEGF가 대장암 발생 및 각 진행단계에서 발현하는 양상 및 예후 관련 인자와의 연관성을 알아보고자 하였다. 대상 및 방법: 대장 선종 32예, 조기 대장암 11예와 진행 대장암 36례의 대장내시경 생검 조직에서 MMP-2, HIF-1α와 VEGF의 mRNA 발현을 역전사 중합효소 연쇄반응을 이용하여 주변의 정상 조직을 기준으로 반정량적으로 측정하였으며, 이 중 암 수술 조직 11예에서 gelatin zymography와 Western blot을 이용하여 활성형 MMP-2 단백과 HIF-1α 단백 발현을 관찰하였다. 결과: MMP-2 mRNA 발현은 대장 선종에 비해 진행 대장암에서 증가하였고(p<0.001), 대장 선종에서 조기 대장암과 진행 대장암으로 갈수록 증가하였다(p<0.05). 대장암에서 MMP-2 mRNA 발현은 림프관 침습이 있는 경우와 중등도와 저분화도일 때 및 병기가 진행함에 따라 증가하였다(p<0.05). Gelatin zymography 결과, 11예 중 10예(91%)의 암조직에서 활성형 MMP-2 단백이 발현되었다. HIF-1α와 VEGF mRNA 발현은 대장 선종에 비해 조기 대장암과 진행 대장암에서 증가하였으나(p<0.05; p<0.001), 조기 대장암과 진행성 대장암 사이에 차이가 없었다. Western blot 결과, 11예 중 9예(82%)의 암조직에서 HIF-1α 단백이 발현되었다. HIF-1α mRNA 발현은 MMP-2 mRNA 및 VEGF mRNA 발현과 유의한 상관관계가 있었다(r=0.52, p< 0.001; r=0.76, p<0.001). 결론: 이번 연구는 대장암 발생 및 진행에 있어서 MMP-2, HIF-1α와 VEGF의 발현 및 상호 연관성을 확인할 수 있었으며, 이들 인자들의 발현이 대장 내 신생물의 악성화 단계 및 악성 병변의 진행을 예측할 수 있는 한 방법이 될 수 있을 것으로 생각한다. 색인단어: Matrix metalloproteinase-2, Hypoxia-inducible factor-1α, Vascular endothelial growth factor, 대장 선종, 대장암