Antioxidant and anti-inflammatory activity of Heritiera fomes (Buch.-Ham), a mangrove plant of the Sundarbans

Islam Md. Emdadul,Islam Kazi Mohammed Didarul,Billah Md. Morsaline,Biswas Rana,Sohrab Md. Hossain,Rahman S. M. Mahbubur 경희대학교 융합한의과학연구소 2020 Oriental Pharmacy and Experimental Medicine Vol.20 No.2

The antioxidant and anti-inflammatory potential of Heritiera fomes ethanolic extract was evaluated.Query Ethanolic extraction of dried and grinded plant leaves and bark was performed. Antioxidant activity was evaluated by 1, 1-diphenyl-2-picryl-hydrazil (DPPH) free radical scavenging assay, ferric reducing antioxidant power (FRAP) and β-carotene bleaching inhibition assay. Total phenolic and flavonoid content were also determined. Anti-inflammatory activity was evaluated by in vitro human RBC membrane stabilizing assay and in vivo mice paw edema test. Ethanolic bark and leaf extracts of H. fomes (S1 and S2, respectively) showed significant scavenging effect on DPPH scavenging 68.51 µg/ml for S1 and 108.64 µg/ml for S2. Potent reduction potential (FRAP) was observed in S1 (83.75 mM of ferrous equivalent) while the FRAP of standard ascorbic acid was found 86.66 μM of ferrous equivalent. S1 also exhibited 87.43% β-carotene bleaching inhibition as comparable to standard butylated hydroxytoluene with 98.85% inhibition. Substantial phenolic and flavonoid content was also observed in S1 (136.83 μg gallic acid equivalent/g of extract and 76.67 μg quercetin equivalent/g of extract, respectively). S1 could provide 61.73% and 53.27% protection of RBC membrane in hypotonicity and heat induced lysis of RBC, respectively while the standard diclofenac sodium provided 91.66% and 86.66% protection, respectively. Furthermore, 44.16% reduction in mice paw edema at 40 μg/kg bw concentration was observed in S1 as compared to standard indomethacine (53.54% in 10 μg/kg bw concentration). The results revealed that the bark extract (S1) of H. fomes possesses significant antioxidant and anti-inflammatory activity.

PREVALENCE OF PARASITES OF WATER BUFFALOES IN BANGLADESH

Islam, F.M.S.,Rahman, M.H.,Chowdhury, S.M.Z.H. Asian Australasian Association of Animal Productio 1992 Animal Bioscience Vol.5 No.4

A total of 480 live buffaloes and 180 visceral samples from Dhaka, Mymensingh, Bogura and Rajshahi were examined for the presence of parasites of water buffaloes in Bangladesh during September, 1988 to August, 1989. The recorded parasites were eight trematodes, two cestodes, fourteen nematodes, two protozoa and two arthropods. The trematodes were Fasciola gigantica (18.9%-46.4%). Paramphistomes (Gigantocotyl explanatum, Ceylonocotyl scoliocoelium, Cotylophoron cotylophorum and Gastrothylax crumenifer (29.5%-48.3%). Schistosoma indicum (1.6%-31.6%), S. spindale (13.9%-27.7%) and S. nasalis (4.6%-8.3%). The cestodes were Hydatid cyst (24.4%), Cysticercus tenuicollis (11.1%). The nematodes were Strongyloides papillosus (14.8%-21.6%), Capillaria spp. (C. bilobata, C. bovis) (8.5%-20.0%), Setaria digitata (7.2%), Onchocerca armillata (27.2%), Thelazia rhodesii (2.3%), Gongylonema pulchrum (3.9%), Oesophagostomum radiatum (6.6%-41.6%), Hookworms (Agriostomum vryburgi, Bunostomum phlebotomum) (8.1%-17.2%), Trichostrongylus axei (11.2%-21.6%), Mecistocirrus digitatus & Haemonchus contortus (15.2%-25.5%) and Toxocara vitulorum (1.1%-9.8%). The protozoa were Eimeria zuerni (2.3%) and Trypanosoma theileri (0.4%). The arthropods were Haemaphysalis bispinosa (8.1%) and Haematopinus tuberculatus (34.6%).

Principal Milk Components in Buffalo, Holstein Cross, Indigenous Cattle and Red Chittagong Cattle from Bangladesh

Islam, M.A.,Alam, M.K.,Islam, M.N.,Khan, M.A.S.,Ekeberg, D.,Rukke, E.O.,Vegarud, G.E. Asian Australasian Association of Animal Productio 2014 Animal Bioscience Vol.27 No.6

The aim of the present study was to get a total physical and chemical characterization and comparison of the principal components in Bangladeshi buffalo (B), Holstein cross (HX), Indigenous cattle (IC) and Red Chittagong Cattle (RCC) milk. Protein and casein (CN) composition and type, casein micellar size (CMS), naturally occurring peptides, free amino acids, fat, milk fat globule size (MFGS), fatty acid composition, carbohydrates, total and individual minerals were analyzed. These components are related to technological and nutritional properties of milk. Consequently, they are important for the dairy industry and in the animal feeding and breeding strategies. Considerable variation in most of the principal components of milk were observed among the animals. The milk of RCC and IC contained higher protein, CN, ${\beta}$-CN, whey protein, lactose, total mineral and P. They were more or less similar in most of the all other components. The B milk was found higher in CN number, in the content of ${\alpha}_{s2}-$, ${\kappa}$-CN and ${\beta}$-lactalbumin, free amino acids, unsaturated fatty acids, Ca and Ca:P. The B milk was also lower in ${\beta}$-lactoglobulin content and had the largest CMS and MFGS. Proportion of CN to whey protein was lower in HX milk and this milk was found higher in ${\beta}$-lactoglobulin and naturally occuring peptides. Considering the results obtained including the ratio of ${\alpha}_{s1}-$, ${\alpha}_{s2}-$, ${\beta}$- and ${\kappa}$-CN, B and RCC milk showed best data both from nutritional and technological aspects.

Preparation and Characterization of Sulfonated Poly(ether Sulfone) Using 4,4-Bis(4-Hydroxylphenyl)valeric Acid for Proton Exchange Membrane Fuel Cell Application

Seo, Dong Wan,Lim, Young Don,Islam Mollah, M. S.,Lee, Soon Ho,Moon, Sang Ho,Pyun, Sang Young,Kim, Whan Gi Trans Tech Publications, Ltd. 2009 Materials science forum Vol.620 No.-

<P>Poly(ether sulfone)s (PES) containing 25-75 mol % valeric acid were prepared with bisphenol A, bis(4-chlorophenyl)sulfone and 4,4-Bis(4-hydroxylphenyl)valeric acid using potassium carbonate in DMAc (dimethylacetamide) at 160 °C. Copolymers containing carboxylacid group were reduced to hydroxy group by BH3 solution 1M in THF and NaBH4 co-catalyst. Sulfonated poly(ether sulfone)s (S-PES) were obtained by reaction of 1,3-propanesultone and the reduced copolymer (PES-OH) with potassium t-butoxide. A series of copolymers were studied by 1H-NMR spectroscopy, differential scanning calorimetry (DSC), and thermo gravimetric analysis (TGA). Sorption experiments were conducted to observe the interaction of sulfonated polymers with water and methanol. The S-PES membranes exhibited proton conductivities from 1.20  10-3 to 3.40  10-3 S/cm, water swell from 12.25 to 31.50 %, IEC from 0.43 to 0.72 meq/g and methanol diffusion coefficients from 3.60  10-7 to 4.90  10-7 cm2/S at 25 °C.</P>

Antioxidant and antibacterial activity of three herbs belonging to Zingiber genus of Bangladesh

Afiya Aunjum,Rana Biswas,Tauhidur Rahman Nurunnabi,S.M. Mahbubur Rahman,Md. Morsaline Billah,Md. Emdadul Islam,Kazi Mohammed Didarul Islam 경희대학교 융합한의과학연구소 2020 Oriental Pharmacy and Experimental Medicine Vol.20 No.3

Apart from boosting flavor, herbs and spices are also known for their preservative, antioxidant, antimicrobial and other medicinal properties. Bioactive metabolites with aspiring prospect have guided the present study to screen for antibacterial and antioxidant activity of three Zingiber plants available in Bangladesh. For that purpose, rhizomes of Zingiber officinale, Z. montanum and Z. zerumbet were extracted with ethanol as solvent system for bioactivity analysis. Antioxidant activity was assessed by employing DPPH free radical scavenging assay, reducing power assay and ferric reducing antioxidant power (FRAP) assay. Z. officinale extract demonstrated the highest free radical scavenging activity ( IC50: 43.65 μg/ml), reducing power ( EC50: 189.026 μg/ml) and FRAP value (137.18 ± 0.116 μM Fe(II)/100 μg dry weight of extract). Moreover, total phenolic, flavonoid and tannin content were determined which significantly correlated (Pearson correlation) with the antioxidant activities. For the evaluation of antibacterial activity, zone of inhibition (ZOI) was measured by disc diffusion bioassay against four Gram positive bacteria Bacillus megaterium, Staphylococcus aureus, Micrococcus spp., and S. epidermidis as well as ten Gram negative bacteria Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, S. paratyphi, Vibrio cholera, Shigella dysenteriae, S. flexneri, Proteus spp., Mycobacterium spp., and Campylobacter spp. Z. montanum extract exhibited significant activity against E. coli (13.67 ± 0.577 mm ZOI) and Micrococcus spp. (14.33 ± 0.763 mm ZOI) if compared to standard erythromycin with ZOI 15.33 ± 0.577 mm and 15.67 ± 0.577 mm, respectively. Furthermore, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of Z. montanum extract were determined against B. megaterium, Micrococcus spp., E. coli and S. paratyphi. Thus, Z. officinale and Z. montanum extracts could be utilized as source and template for the synthesis of potential drugs and food supplements as well.

The comparison of naturally weathered oil and artificially photo-degraded oil at the molecular level by a combination of SARA fractionation and FT-ICR MS

Islam, A.,Cho, Y.,Yim, U.H.,Shim, W.J.,Kim, Y.H.,Kim, S. Elsevier Scientific Pub. Co 2013 Journal of hazardous materials Vol.263 No.2

Two sets of oil samples, one obtained from different weathering stages of the M/V Hebei Spirit oil spill site and the other prepared by an in vitro photo-degradation experiment, were analyzed and compared at the molecular level by atmospheric pressure photo-ionization coupled with Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS). For a more detailed comparison at the molecular level, the oil samples were separated into saturate, aromatic, resin, and asphaltene (SARA) fractions before MS analysis. Gravimetric analysis of the SARA fractions revealed a decreased weight percentage of the aromatic fraction and an increased resin fraction in both sets of samples. Molecular-level investigations of the SARA fractions showed a significant reduction in the S<SUB>1</SUB> class in the saturate fraction and increase of S<SUB>1</SUB>O<SUB>1</SUB> class compounds with high DBE values in resin fraction. Levels of N<SUB>1</SUB> and N<SUB>1</SUB>O<SUB>1</SUB> class compounds resulting in protonated ions (presumably basic nitrogen compounds) increased after degradation compared to compounds generating molecular ions (presumably non-basic nitrogen compounds). This study revealed changes occurring in heteroatom polar species of crude oils such as sulfur and nitrogen containing compounds that have not been easily detected with conventional GC based techniques.

비료 장기연용에 따른 논토양내 군집의 기능적 다양성과 효소활성 평가

P.S차우한 ( P. S. Chauhan ),라쉐드이슬람 ( Rashedul Islam ),임우종 ( Woo Jong Yim ),P.팔라니아판 ( P. Palaniappan ),C.C.샤골 ( C. C. Shagol ),사동민 ( Tong Min Sa ) 한국토양비료학회 2010 한국토양비료학회 학술발표회 Vol.2010 No.-

Evaluation of microbiological and physicochemical profile of some herbal preparations manufactured by pharmaceutical and herbal manufacturers in Bangladesh

A. F. M. Mahmudul Islam,Md. Farhan Khalik,Nizam Uddin,Md. Sazzad Hossain,Md. Monir Hossain,Md. Mahadi Hasan,S. M. Fahad,Pijus Saha 한국약제학회 2015 Journal of Pharmaceutical Investigation Vol.45 No.2

The aim of this study was to scrutinize thephysicochemical and qualitative microbial examination of 30 different (of various dosage forms) herbal medicinalproducts marketed by pharmaceutical and herbal manufacturersin Bangladesh. The microbial evaluation includedtotal viable aerobic bacteria, Escherichia coli, fungi andStaphylococcus aureus count; physicochemical propertieslike weight variation, hardness, disintegration time, friabilityand density. The IMViC (indole, methyl red, Voges–Proskauer and citrate utilization) tests were frequentlyemployed for identification of E. coli and S. aureus. Totalviable aerobic bacterial counts in the samples analyzed wereranged from 3.8 × 10⁴ to 3.2 × 108 CFU/ml or CFU/g and 36.67 % were within BP standard limit. S. aureus wasdetected in 53.33 % (16) of the samples, ranged from anestimated 3 × 10² to 9.2 × 106 CFU/ml or CFU/g whichwere above the USP standard. E. coli was detected in 40 %(12) of the samples, ranging from 1 × 10² to 4.8 × 10⁴CFU/ml or CFU/g that were above the USP standard. Theranges of the fungi counts were 3.4 × 10³ – 3.1 × 106 CFU/ml or CFU/g and 46.67 %of which were within BP standard. Physicochemical properties of herbal products manufacturedby pharmaceutical manufacturers were found betterthan that of the herbal manufacturers. From the label andpack insert of herbal products, definite release patterninformation weren’t obtained and the majority of herbalproducts showed scattered disintegration time. In order toreduce the potential health related complications, there isnecessity of constant monitoring and control of the standardsof herbal medicine products available in the Bangladeshimarket.

Measurement of burr removal rate and analysis of machining parameters in ultrasonic assisted dry EDM (US-EDM) for deburring drilled holes in CFRP composite

Kurniawan, Rendi,Thirumalai Kumaran, S.,Arumuga Prabu, V.,Zhen, Yu,Park, Ki Moon,Kwak, Ye In,Mofizul Islam, Md.,Ko, Tae Jo Elsevier 2017 MEASUREMENT -LONDON- Vol.110 No.-

<P><B>Abstract</B></P> <P>An ultrasonic assisted dry electrical discharge machining (US-EDM) process in a gaseous fluid medium was proposed to remove the burrs formed on the exit region of a drilled hole. In preliminary experiment, three different electrode tools (copper, brass, and aluminum) were utilized. In secondary experiment, US-EDM and dry-EDM were compared and performed using the copper tool. US-EDM parameters, such as capacitance (C), pulse-on time (T<SUB>ON</SUB>), and vibration amplitude (A<SUB>p-p</SUB>) were considered as functions of the predicted burr removal rates (BRRs) model. Based on signal to noise (S/N) ratio analysis, machining parameters C=10<SUP>−2</SUP> µF, T<SUB>ON</SUB> =150µs, and A<SUB>p-p</SUB> =4.919µm provided the optimal BRR. The BRR was affected the most by capacitance, followed by pulse-on time and ultrasonic vibration amplitude. The copper tool provided a higher BRR than other tools. US-EDM is considerably effective when T<SUB>ON</SUB> is low and the performance of US-EDM is better than that of Dry-EDM. Scanning electron microscopy (SEM) analysis showed that the US-EDM method created a heat-affected zone surrounding the machined surface of the deburred exit hole in range of 200µm–500µm.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The novelty of a burr removal rate (BRR) model was proposed and validated in this study. </LI> <LI> The influence of the US-EDM process parameters on the BRR value was studied. </LI> <LI> The relationship between the input and output processes was evaluated statistically. </LI> <LI> The optimal machining parameter for the BRR value was validated. </LI> <LI> The comparison between US-EDM and Dry-EDM process was evaluated. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

A Study of the Milking and Reproduction Performances of Grazing Indigenous Cattle at a Semi Urban Area of Bangladesh

Islam, S.S.,Ashraf, A.,Islam, A.B.M.M. Asian Australasian Association of Animal Productio 2000 Animal Bioscience Vol.13 No.6

The study was conducted at semi urban area in Bangladesh. It was based on a field survey by a prepared questionnaire. Various milking and reproduction performance were analyzed. The effects of grazing hour were found significant on age at weaning (AW) (p<0.001), age at first heat (AFH) (p<0.001), age at first conception (AF conception) (p<0.001), age at first calving (AF calving) (p<0.001), post partum heat period (PPHP) (p<0.001), calving interval (CI) (p<0.001), lactation length (LL) (p<0.001) and total lactational production (TLP) (p<0.001). The effects of concentrate feed were significant on AW (p<0.01), AFH (p<0.01), AF conception (p<0.001), AF calving (p<0.001), PPHP (p<0.001) CI (p<0.001), LL (p<0.001) and TLP (p<0.001). The effects of management level were significant on AW (p<0.001), PPHP (p<0.01), CI (p<0.001), daily milk yield (DMY) (p<0.05) and TLP (p<0.001). The overall mean values were $251.88{\pm}2.97$ days for AW, $37.29{\pm}0.33$ months for AFH, $38.43{\pm}0.34$ months for AF conception, $47.62{\pm}0.34$ months for AF calving, $1.30{\pm}0.02$ number of services per conception (NSPC), $191.57{\pm}3.92$ days for PPHP, $17.02{\pm}0.15$ months for CI, $2.49{\pm}0.06kg$ for DMY, $247.23{\pm}3.51$ days for LL and $590.40{\pm}15.00kg$ for TLP.