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      • KCI등재

        FATIGUE FEATURES EXTRACTION OF ROAD LOAD TIMEDATA USING THE S-TRANSFORM

        S. ABDULLAH,C. K. E. NIZWAN,M. F. M. YUNOH,M. Z. NUAWI,Z. M. NOPIAH 한국자동차공학회 2013 International journal of automotive technology Vol.14 No.5

        This paper presents the algorithm development of a new fatigue data editing technique using S-T approach. Ingeneral, the S-transform (S-T) is a time-frequency spectral localization method which performs a multi-resolution analysis onsignal. This method represents a better time-frequency resolution especially for non-stationary signal analysis. This techniquewas developed to produce shortened fatigue data for fatigue durability testing. The S-T method was applied to detect thedamaging events contained in the fatigue signals due to high S-T spectrum location. The damaging events were extracted froman original fatigue signal to produce the shortened edited signal which has equivalent fatigue damage. Three types of road loadfatigue data were used for simulation purpose, pave track, highway and country road. In this study, an algorithm wasdeveloped, to detect the damaging events in the original fatigue signal. The algorithm can be used to extract the fatiguedamaging events and these events were combined in order to produce a new edited signal which neglect the low amplitudecycles. The edited signal consists of the majority of the original fatigue damage in the shortened signal with 15-25% timereduction. Thus, it has been suggested that this shortened signal can then be used in the laboratory fatigue testing for thepurpose of accelerated fatigue testing.

      • SCIESCOPUSKCI등재

        Prion Protein Genotypes in Pakistani Goats

        Babar, M.E.,Nawaz, M.,Nasim, A.,Abdullah, M.,Imran, M.,Jabeen, R.,Chatha, S.A.,Haq, A.U.,Nawaz, A.,Mustafa, H.,Nadeem, A. Asian Australasian Association of Animal Productio 2008 Animal Bioscience Vol.21 No.7

        The PCR-amplified prion protein (PrP) gene was sequenced to determine the frequency of scrapie-associated as well as novel PrP genotypes in 72 healthy goats representing five breeds. A total of six genotypes were detected, resulting from the three reported 143 (H/R), 154 (R/H) and 240 (S/P) and the two novel 39 (S/R) and 185 (I/F) amino acid polymorphisms. Of the four silent mutations 42 (a$\rightarrow$g), 138 (c$\rightarrow$t), 231 (c$\rightarrow$a) and 237 (g$\rightarrow$c) detected in this study, 237 (g$\rightarrow$c) is novel. A genotype (SIP/RFP) harboring three amino acid polymorphisms 39 (S/R), 185 (I/F) and 240 (S/P) was found in few goats. Although both scrapie-associated genotypes with 143 (H/R) and 154 (R/H) polymorphisms and others with 39 (S/R), 185 (I/F) and 240 (S/P) polymorphisms were present in the studied Pakistani goats, their frequency was lower than that of the wild-type genotype SHRIS/SHRIS (34.7%). These results emphasize the need for further sequencing of the PrP gene in a large number of goats representing the five studied breeds, so that overall PrP variability can be assessed in these breeds in research addressing future concerns about scrapie.

      • KCI등재

        Sacral Neuromodulation in Patients With a Cardiac Pacemaker

        Abdullah A. Gahzi,Dean S. Elterman,Magdy Hassouna 대한배뇨장애요실금학회 2016 International Neurourology Journal Vol.20 No.3

        The objective of this study was to describe our experience using sacral neuromodulation to treat urinary urgency, frequency, urge incontinence, and chronic urinary retention in patients with cardiac pacemakers. With the increasingly widespread use of InterStim for bladder function restoration, we are seeing more complex patients with multiple comorbidities, including cardiac conditions. Herein, we report 3 cases of individuals with cardiac pacemakers who underwent InterStim implantation to treat urinary conditions. This study is a case series of 3 patients with cardiac pacemakers who underwent sacral neuromodulation to treat refractory voiding dysfunction. The initial patient screening for InterStim therapy involved percutaneous nerve evaluation (PNE), in which a temporary untined lead wire was placed through the S3 foramen. Patients who did not respond to PNE proceeded to a staged implant. All patients in this study had a greater than 50% improvement of their urinary symptoms during the initial trial and underwent placement of the InterStim implantable pulse generator (IPG). Postoperative programming was done under electrocardiogram monitoring by a cardiologist. No interference was observed between the Inter- Stim IPG and the cardiac pacemaker. In this group of patients, sacral neuromodulation in the presence of a cardiac pacemaker appears to have been safe.

      • SCIESSCISCOPUSKCI등재

        The Relationship between the Number of Manic Episodes and Oxidative Stress Indicators in Bipolar Disorder

        Sü,leyman Akarsu,Abdullah Bolu,Emre Aydemir,Selma Bozkurt Zincir,Yasemin Gü,lcan Kurt,Serkan Zincir,Murat Erdem,Ö,zcan Uzun 대한신경정신의학회 2018 PSYCHIATRY INVESTIGATION Vol.15 No.5

        Objective Bipolar disorder (BD) is a chronic mood disorder characterized by recurrent episodes that has a lifetime prevalence of 0.4– 5.5%. The neurochemical mechanism of BD is not fully understood. Oxidative stress in neurons causes lipid peroxidation in proteins associated with neuronal membranes and intracellular enzymes and it may lead to dysfunction in neurotransmitter reuptake and enzyme activities. These pathological processes are thought to occur in brain regions associated with affective functions and emotions in BD. The relationship between the number of manic episodes and total oxidant-antioxidant capacity was investigated in this study. Methods Eighty-two BD patients hospitalized due to manic symptoms and with no episodes of depression were enrolled in the study. Thirty of the 82 patients had had their first episode of mania, and the other 52 patients had had two or more manic episodes. The control group included 45 socio-demographically matched healthy individuals. Serum total antioxidant capacity (TAC) and total oxidant capacity (TOC) measurements of the participants were performed. The oxidative stress index (OSI) was calculated by TOC/TAC. Results There were no significant differences in OSI scores between BD patients with first-episode mania and BD patients with more than one manic episode. However, OSI scores in both groups were significantly higher than in the control group. TOC levels of BD patients with first-episode mania were found to be significantly higher than TOC levels of BD patients with more than one manic episode and healthy controls. There were no significant differences in TAC levels between BD patients with first-episode mania and BD patients with more than one manic episode. TAC levels in both groups were significantly higher than in the control group. Conclusion Significant changes in oxidative stress indicators were observed in this study, confirming previous studies. Increased levels of oxidants were shown with increased disease severity rather than with the number of manic episodes. Systematic studies, including of each period of the disorder, are needed for using the findings indicating deterioration of oxidative parameters.

      • KCI등재

        Decreased Prolidase Activity in Patients with Posttraumatic Stress Disorder

        Süleyman Demir,Mahmut Bulut,Abdullah Atli,I·brahim Kaplan,Mehmet Cemal Kaya,Yasin Bez,Pınar Güzel Özdemir,Aytekin Sır 대한신경정신의학회 2016 PSYCHIATRY INVESTIGATION Vol.13 No.4

        ObjectiveaaMany neurochemical systems have been implicated in the development of Posttraumatic Stress Disorder (PTSD). The prolidase enzyme is a cytosolic exopeptidase that detaches proline or hydroxyproline from the carboxyl terminal position of dipeptides. Prolidase has important biological effects, and to date, its role in the etiology of PTSD has not been studied. In the present study, we aimed to evaluate prolidase activity in patients with PTSD. MethodsaaThe study group consisted of patients who were diagnosed with PTSD after the earthquake that occurred in the province of Van in Turkey in 2011 (n=25); the first control group consisted of patients who experienced the earthquake but did not show PTSD symptoms (n=26) and the second control group consisted of patients who have never been exposed to a traumatic event (n=25). Prolidase activities in the patients and the control groups were determined by the ELISA method using commercial kits. ResultsaaProlidase activity in the patient group was significantly lower when compared to the control groups. Prolidase activity was also significantly lower in the traumatized healthy subjects compared to the other healthy group (p<0.01). ConclusionaaThe findings of the present study suggest that the decrease in prolidase activity may have neuroprotective effects in patients with PTSD.

      • KCI등재

        Low-dose Clozapine-induced Seizure: A Case Report

        Abdullah Bolu,Süleyman Akarsu,Erdal Pan,Emre Aydemir,Taner Oznur 대한정신약물학회 2017 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.15 No.2

        Seizures are believed to be a dose-dependent side effect of clozapine. In this case report, we describe a patient who had tonic-clonic seizures after using a low dose clozapine who did not have any seizure risk. The 29-year-old male patient had been followed-up with a diagnosis of schizophrenia for about 5 years. When using clozapine 200 mg/day he had a tonic-clonic seizure with bilateral diffuse epileptic activity in electroencephalography (EEG). In the literature, there are a few case reports about low-dose clozapine-induced seizure. Seizures were observed in our case with a low dose of clozapine (200 mg/day) making this case remarkable. EEG monitoring at regular intervals and examination of plasma levels of clozapine could be useful in preventing the development of seizures.

      • KCI등재

        Evaluation of Paraoxonase, Arylesterase and Malondialdehyde Levels in Schizophrenia Patients Taking Typical, Atypical and Combined Antipsychotic Treatment

        Mehmet Güneş,Mehmet Akif Camkurt,Mahmut Bulut,Süleyman Demir,Aslıhan Okan İbiloğlu,Mehmet Cemal Kaya,Abdullah Atlı,İbrahim Kaplan,Aytekin Sir 대한정신약물학회 2016 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.14 No.4

        Objective: Human serum paraoxonase (PON1) prevents lipids from peroxidation and functions as an antioxidant mechanism. Malonyldialdehyde (MDA) is the final product of lipid peroxidation and can be used as an indicator of oxidative stress. The aim of this study was to investigate PON1, MDA, and arylesterase (ARY) levels in schizophrenic patients who are taking typical, atypical, or combined (typical and atypical) antipsychotic drug treatment, with respect to those of healthy controls. Methods: We evaluated 41 patients (11 taking typical antipsychotics, 19 taking atypical antipsychotics, 11 taking combined antipsychotics) and 43 healthy controls. Results: MDA levels were higher in schizophrenic patients taking typical antipsychotics compared with healthy controls (p=0.001). ARY levels were higher in patients taking atypical antipsychotics compared with healthy controls (p=0.005). PON1 activity was similar in all groups. Conclusion: Our results indicate that treatment with typical antipsychotic drugs could be related to increased MDA levels; and antipsychotic medication may increase PON1 levels in schizophrenic patients.

      • Effect of three-dimensional thermal stresses on torsional vibration of cracked nanorods surrounded by an elastic medium

        Abdullah, Sardar S.,Hashemi, Shahrokh H.,Hussein, Nazhad A.,Nazemnezhad, Reza Techno-Press 2021 Advances in nano research Vol.11 No.3

        The effect of thermal stresses on the torsional vibration of non, single, and double-cracked nanorods surrounded by an elastic medium is investigated. The differential constitutive relation of the nonlocal theory is applied to the motion equation. Three-dimensional linear thermal strains raised from the thermal stresses are derived using nonlinear Green's strains. The surrounding elastic medium acts as infinite torsional springs. The crack is modeled as a rotational spring. Using Hamilton's principle, the motion equation is obtained. Effect of the crack position and severity, number of cracks, high and low temperatures, nonlocal coefficient, elastic medium stiffness, and nanorod length are examined. The temperature effect on the frequencies depends on the values of the crack parameters, crack numbers, elastic medium stiffness, and nanorod length, and it is independent of the nonlocal scale coefficient. The crack leads to a decrease in the frequencies at any temperature. The elastic medium causes an increase in the frequencies at any temperature.The effect of thermal stresses on the torsional vibration of non, single, and double-cracked nanorods surrounded by an elastic medium is investigated. The differential constitutive relation of the nonlocal theory is applied to the motion equation. Three-dimensional linear thermal strains raised from the thermal stresses are derived using nonlinear Green's strains. The surrounding elastic medium acts as infinite torsional springs. The crack is modeled as a rotational spring. Using Hamilton's principle, the motion equation is obtained. Effect of the crack position and severity, number of cracks, high and low temperatures, nonlocal coefficient, elastic medium stiffness, and nanorod length are examined. The temperature effect on the frequencies depends on the values of the crack parameters, crack numbers, elastic medium stiffness, and nanorod length, and it is independent of the nonlocal scale coefficient. The crack leads to a decrease in the frequencies at any temperature. The elastic medium causes an increase in the frequencies at any temperature.

      • SCIESCOPUSKCI등재

        Growth Performance, Carcass and Meat Characteristics of Black Goat Kids Fed Sesame Hulls and Prosopis juliflora Pods

        Abdullah, Abdullah Y.,Obeidat, Belal S.,Muwalla, Marwan M.,Matarneh, Sulaiman K.,Ishmais, Majdi A. Abu Asian Australasian Association of Animal Productio 2011 Animal Bioscience Vol.24 No.9

        Finding alternative feeds, such as sesame hulls and Prosopis juliflora species can attenuate difficulties of feed shortage and reduce the cost of animal feed in arid and semi-arid countries. Thirty-two Black male kids with similar initial weights (BW = $16.7{\pm}0.80\;kg$) and $120{\pm}5\;d$ of age, were used to evaluate the effect of replacing barley grains and soybean meal with Prosopis juliflora pods (PJP) and sesame hulls (SH) on growth performance, digestibility and carcass and meat characteristics. Kids were equally divided into four dietary treatment groups for an 84-d fattening period. Treatment diets had similar crude protein (CP) and metabolizable energy (ME). The treatment groups were: (T1) no PJP nor SH, (T2) 10% PJP and 20% SH, (T3) 15% PJP and 15% SH, and (T4) 20% PJP and 10% SH. A tendency was detected (p<0.08) for dry matter (DM), crude protein (CP), organic matter (OM) and neutral detergent fiber (NDF) intakes that were greater for T2 than T3 and T4 while T1 was not different from all other treatment groups. Ether extract (EE) intake was the greatest (p<0.05) for T2 and the lowest for T1. Acid detergent fiber (ADF) intake was greater (p<0.05) for T2 than T1 while T3 and T4 were intermediate. Final live weight, average daily gain (ADG) and feed conversion ratio (FCR) were comparable among different treatment groups. Digestibility of DM, OM, CP, NDF and ADF were similar among all treatment groups, however, EE digestibility was the lowest (p<0.05) for T1 when compared to other treatments. In addition, nitrogen intake, nitrogen in urine and retained and retention percentages were similar among all treatment groups. However, N loss in feces was higher (p<0.05) for T2 than T3 and T4 while T1 was intermediate. No differences were observed among treatment groups with respect to fasting live weight, hot and cold carcass weights, dressing-out percentages, mesenteric fat, visceral organs, carcass cuts percentages and carcass linear dimensions. No differences were also observed for dissected loin, leg, rack and shoulder tissues except in the total bone % for loin cuts and in the meat to bone ratio for rack cuts. T3 has the greatest total bone % and the lowest meat to bone ratio when compared to all other treatment groups. No differences were observed between treatment groups in all quality characteristics of the longissimus muscle. The present study demonstrates the potential of using PJP and SH for growing kids without adverse effects on growth performance, carcass characteristics and meat quality.

      • KCI등재

        EMISSION ANALYSIS OF A COMPRESSED NATURAL GAS DIRECTINJECTION ENGINE WITH A HOMOGENOUS MIXTURE

        S. ABDULLAH,W. H. KURNIAWAN,M. KHAMAS,Y. ALI 한국자동차공학회 2011 International journal of automotive technology Vol.12 No.1

        In an era in which environmental pollution and depletion of world oil reserves are of major concern, emissions produced by automotive vehicles need to be controlled and reduced. An ideal solution is to switch to a cleaner fuel such as natural gas, which generates cleaner emissions. In addition, control over the in-cylinder air-fuel mixture can be best achieved through a direct-injection mechanism, which can further improve combustion efficiency. This need for cleaner automobiles provides the motivation for this paper’s examination of the use of computational fluid dynamic (CFD) simulations to analyze the concentrations of the exhaust gases produced by a compressed natural gas engine with a direct-fuel-injection system. In this work, a compressed natural gas direct-injection engine has been designed and developed through a numerical simulation using computational fluid dynamics (CFD) to provide an insight into complex in-cylinder behavior. The emissions analyzed in this study were carbon monoxide (CO), nitric oxide (NO) and carbon dioxide (CO2), i.e. the main pollutants produced by natural gas combustion. Based on a stoichiometric mixture, the concentrations of CO and NO were computed using the dissociation of carbon dioxide and the extended Zeldovich mechanism. CO2 was calculated using a mass balance of the species involved in the combustion process. The simulation results were then compared with the experimental data generated by a single-cylinder research engine test rig. A good agreement was obtained with the experimental data for the engine speeds considered for all emissions concentrations.

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