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( Ranhee Kim ),( Seung Mi Lee ),( Su Jin Sung ),( Mi Rim Kim ),( Chan-wook Park ),( Joong Shin Park ),( Jong Kwan Jun ) 대한산부인과학회 2019 대한산부인과학회 학술대회 Vol.105 No.-
Objective: Twin to twin transfusion syndrome (TTTS) is a complication unique to monochorionic diamniotic (MCDA) twin pregnancy that is caused by vascular anastomosis in a shared placenta. To date, a trial of labor is considered in uncomplicated MCDA twins, but data regarding the trial of labor in MCDA twin pregnancies complicated with TTTS is still insufficient. The study aimed to determine the possibility of vaginal deliveries in MCDA twin pregnancies affected by TTTS. Methods: This is a retrospective cohort study of MCDA twin pregnant women with TTTS who attempted a trial of labor within the study period (July, 2007 ~ January, 2019). Cases not included in the study were non-reassuring antepartum fetal heart rate (FHR) pattern needing urgent cesarean delivery, one or both antepartum fetal demise, and non-viable preterm birth. Clinical characteristics and pregnancies outcomes were collected from the electronic medical records. Results: Among 88 pregnant women with TTTS, 21 cases were excluded due to one or both fetal death, 3 cases due to non-viable preterm birth, and 14 cases due to indications for cesarean delivery, and 28 cases due to emergency cesarean delivery because of abnormal FHR pattern during antepartum periods. Among the remaining 22 women, 21 women adopted trial of labor, and 19 women gave vaginal birth successfully. Only one woman out of 18 women underwent emergency cesarean delivery after trial of labor due to non-reassuring fetal heart rate pattern during the intrapartum period. One neonatal death was reported in this study cohort. Conclusion: In TTTS pregnancies with reassuring antepartum FHR monitoring, vaginal delivery can be attempted like other uncomplicated MCDA twin pregnancies. Further studies are needed to determine neonatal and maternal outcomes after trial of labor in TTTS.
Park, Ranhee,Lim, Sang Ho,Han, Sun-Ho,Lee, Min Young,Park, Jinkyu,Lee, Chi-Gyu,Song, Kyuseok Korean Society for Mass Spectrometry 2016 Mass spectrometry letters Vol.7 No.2
Multi-collector inductively coupled plasma mass spectrometry (MC-ICP-MS) is currently used in our laboratory for isotopic and quantitative analyses of nuclear materials at ultra-trace levels in environmental swipe samples, which is a very useful for monitoring undeclared nuclear activities. In this study, to improve measurement precisions of uranium isotopes at ultratrace levels, we adopted a desolvating nebulizer system (Aridus-II, CETAC., USA), which can improve signal sensitivity and reduce formation of uranium hydride. A peristaltic pump was combined with Aridus-II in the sample introduction system of MC-ICP-MS to reduce long-term signal fluctuations by maintaining a constant flow rate of the sample solution. The signal sensitivity in the presence of Aridus-II was improved more than 10-fold and the formation ratio of UH/U decreased by 16- to 17- fold compared to a normal spray chamber. Long-term signal fluctuations were significantly reduced by using the peristaltic pump. Detailed optimizations and evaluations with uranium standards are also discussed in this paper.
Intrafetal Laser Treatment for Selective Feticide in Monochorionic Multiple Pregnancies
Ranhee Kim,Seung Mi Lee,Sohee Kim,Young Mi Jung,So Yeon Kim,Chan-Wook Park,Joong Shin Park,Jong Kwan Jun 대한주산의학회 2020 Perinatology Vol.31 No.3
Intrafetal coagulation by a radiofrequency ablation (RFA) device has traditionally been used for selective feticide in complicated monochorionic multiple pregnancies. However, as RFA is not feasible in early pregnancy, intrafetal laser coagulation has recently been suggested as an alternative method in the early mid-trimester period. This study aimed to report our experience of utilizing intrafetal laser coagulation for selective feticide in early complicated monochorionic multiple pregnancies. Three monochorionic multiple pregnancies that were treated with intrafetal laser coagulation before 20 weeks were described. Sonographic findings during pregnancy, antepartum course, and intrafetal laser coagulation procedure were reviewed, along with their perinatal outcomes. Indications were twin reversed arterial perfusion sequence in two cases, and dichorionic tri-amniotic triplets complicated with twin-to-twin transfusion syndrome in one case. Intrafetal laser coagulation was successful in all three cases, with favorable neonatal outcomes.
( Ranhee Park ),( Sang Ho Lim ),( Sun-ho Han ),( Min Young Lee ),( Jinkyu Park ),( Chi-gyu Lee ),( Kyuseok Song ) 한국질량분석학회 2016 Mass spectrometry letters Vol.7 No.2
Multi-collector inductively coupled plasma mass spectrometry (MC ICP-MS) is currently used in our laboratory for isotopic and quantitative analyses of nuclear materials at ultra trace levels in environmental swipe samples, which is a very useful for monitoring undeclared nuclear activities. In this study, to improve measurement precisions of uranium isotopes at ultratrace levels, we adopted a desolvating nebulizer system (Aridus II, CETAC., USA), which can improve signal sensitivity and reduce formation of uranium hydride. A peristaltic pump was combined with Aridus-II in the sample introduction system of MC-ICP-MS to reduce long-term signal fluctuations by maintaining a constant flow rate of the sample solution. The signal sensitivity in the presence of Aridus-II was improved more than 10-fold and the formation ratio of UH/U decreased by 16- to 17- fold compared to a normal spray chamber. Long-term signal fluctuations were significantly reduced by using the peristaltic pump. Detailed optimizations and evaluations with uranium standards are also discussed in this paper.
Lim, Sang Ho,Han, Sun-Ho,Park, Jong-Ho,Park, Ranhee,Lee, Min Young,Park, Jinkyu,Lee, Chi-Gyu,Song, Kyuseok Korean Society for Mass Spectrometry 2015 Mass spectrometry letters Vol.6 No.3
Suitable analytical procedures for the bulk analysis of ultra-trace amounts of uranium and plutonium have been developed using multi-collector inductively coupled mass spectrometry (MC-ICP-MS). The quantification and determination of the isotopic ratios of uranium and plutonium in three simulated swipe samples, a swipe blank, and a process blank were performed to validate the analytical performance. The analytical results for the simulated swipe samples were in good agreement with the certified values, based on the measurement quality goals for the analysis of bulk environmental samples recommended by the International Atomic Energy Agency (IAEA)