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Recurrent pregnancy loss: can factor V Leiden mutations be a cause
R R N Reddy,Deepti Mutreja,Nikhil Moorchung,Indrayani Mukhopadhyay 대한산부인과학회 2019 Obstetrics & Gynecology Science Vol.62 No.3
The role of Factor V Leiden (FVL) mutation in recurrent miscarriages has been disputed. It has been hypothesized thatFVL mutation in patients with recurrent miscarriages is treatable. In this study, we evaluated 78 pregnant womenfor FVL mutations, among whom 50 had a history of recurrent miscarriages. Only 1 (2%) of the woman was positivefor heterozygous FVL mutation. The incidence of FVL mutations in patients with recurrent pregnancy loss had anodds ratio of 1.72 (95% confidence interval, 0.0681–43.8257; P>0.05). However, the findings were not statisticallysignificant. Thus, we suggest that FVL mutation study may not be included in the battery of tests for recurrentmiscarriages in the Indian population.
Mukhopadhyay, S.,Deopura, B.L.,Alagirusamy, R. The Korean Fiber Society 2006 Fibers and polymers Vol.7 No.4
High Modulus and high tenacity polypropylene fibers have been prepared by drawing on a gradient heater. Results show that fiber properties are significantly affected by temperature profiles of final stage drawing on a gradient heater. The gradient drawn filaments showed superior mechanical properties when compared to filaments drawn over a constant temperature heater. Fibers with initial modulus of 16.4 GPa and tenacity of 670 MPa have been manufactured in the process. The nature of the gradient drawing had a significant effect on end properties. The superior mechanical properties are attributed to the high crystal perfection and crystallinity and low void fractions obtained at high draw ratios when drawn over a gradient heater.
DYNAMICS OF A DELAY-DIFFUSION PREY-PREDATOR MODEL WITH DISEASE IN THE PREY
MUKHOPADHYAY, B.,BHATTACHARYYA, R. 한국전산응용수학회 2005 Journal of applied mathematics & informatics Vol.17 No.1
A mathematical model dealing with a prey-predator system with disease in the prey is considered. The functional response of the predator is governed by a Hoilling type-2 function. Mathematical analysis of the model regarding stability and persistence has been performed. The effect of delay and diffusion on the above system is studied. The role of diffusivity on stability and persistence criteria of the system has also been discussed.
Subfertility in Males: An Important Cause of Bull Disposal in Bovines
Mukhopadhyay, C.S.,Gupta, A.K.,Yadav, B.R.,Khate, K.,Raina, V.S.,Mohanty, T.K.,Dubey, P.P. Asian Australasian Association of Animal Productio 2010 Animal Bioscience Vol.23 No.4
The study had two objectives, namely, to estimate the andrological disorders leading to disposal of Karan Fries (KF), Sahiwal cattle and Murrah buffalo bulls and to study the effect of various factors (species/breeds, season of birth and period of birth) on male reproductive parameters. Records on occurrence of subfertility problems and disposal pattern of bulls maintained at the National Dairy Research Institute herd were collected for 15 years (1991 to 2005). Percentage of bulls producing freezable semen was less in the crossbred cattle (58.46%) as compared to Sahiwal (81.69%) and Murrah bulls (81.05%). Various subfertility traits like poor libido and unacceptable seminal profile were found to be the significant reasons (p<0.01) for culling of the breeding bulls. Inadequate sex drive was the main contributing factor for bull disposal in Sahiwal (22.55%) and Murrah bulls (15.12%) whereas poor semen quality and freezability were most frequently observed in KF bulls (24.29 and 7.29 percent, respectively). Least squares analyses of different male reproductive parameters showed that species/breeds had significant effect (p<0.05) on all traits except for frozen semen production periods (FSPP). Periods of birth were significantly different (p<0.05) for all traits except for semen volume. Age at first semen collection (AFSC), age at first semen freezing (AFSF) and age at disposal (AD) were highest in Murrah, while frozen semen production period (FSPP) and semen production period (SPP) were highest in KF and lowest in Sahiwal. The age at first semen donation and breeding period could be reduced by introducing the bulls to training at an early age. These results revealed a declining trend in AFSC, AFSF, FSPP, SPP and AD, thereby indicating an improvement in reproductive performance over the years. The age at first semen donation in bovines can be reduced by introducing the young male calves to training at an early age, which could increase the dosage of semen obtained from each male.
TEMPORAL AND SPATIO-TEMPORAL DYNAMICS OF A MATHEMATICAL MODEL OF HARMFUL ALGAL INTERACTION
Mukhopadhyay, B.,Bhattacharyya, R. The Korean Society for Computational and Applied M 2009 Journal of applied mathematics & informatics Vol.27 No.1
The adverse effect of harmful plankton on the marine ecosystem is a topic of deep concern. To investigate the role of such phytoplankton, a mathematical model containing distinct dynamical equations for toxic and non-toxic phytoplankton is analyzed. Stability analysis of the resulting three equation model is carried out. A continuous time variation in toxin liberation process is incorporated into the model and a stability analysis of the resulting delay model is performed. The distributed delay model is then extended to include the spatial distribution of plankton and the delay-diffusion model is analyzed with spatial and spatiotemporal kernels. Conditions for diffusion-driven instability in both the cases are derived and compared to explore the significance of these kernels. Numerical studies are performed to justify analytical findings.
Temporal and spatio-temporal dynamics of a mathematical model of harmful algal interaction
B. Mukhopadhyay,R. Bhattacharyya 한국전산응용수학회 2009 Journal of applied mathematics & informatics Vol.27 No.1
The adverse effect of harmful plankton on the marine ecosystem is a topic of deep concern. To investigate the role of such phytoplankton, a mathematical model containing distinct dynamical equations for toxic and non-toxic phytoplankton is analyzed. Stability analysis of the resulting three equation model is carried out. A continuous time variation in toxin liberation process is incorporated into the model and a stability analysis of the resulting delay model is performed. The distributed delay model is then extended to include the spatial distribution of plankton and the delay-diffusion model is analyzed with spatial and spatiotemporal kernels. Conditions for diffusion-driven instability in both the cases are derived and compared to explore the significance of these kernels. Numerical studies are performed to justify analytical findings The adverse effect of harmful plankton on the marine ecosystem is a topic of deep concern. To investigate the role of such phytoplankton, a mathematical model containing distinct dynamical equations for toxic and non-toxic phytoplankton is analyzed. Stability analysis of the resulting three equation model is carried out. A continuous time variation in toxin liberation process is incorporated into the model and a stability analysis of the resulting delay model is performed. The distributed delay model is then extended to include the spatial distribution of plankton and the delay-diffusion model is analyzed with spatial and spatiotemporal kernels. Conditions for diffusion-driven instability in both the cases are derived and compared to explore the significance of these kernels. Numerical studies are performed to justify analytical findings
Dynamics of a delay-diffusion prey-predator model with disease in the prey
B. Mukhopadhyay,R. Bhattacharyya 한국전산응용수학회 2005 Journal of applied mathematics & informatics Vol.17 No.1-2
A mathematical model dealing with a prey-predator system with disease in the prey is considered. The functional response of the predator is governed by a Hoilling type-II function. Mathematical analysis of the model regarding stability and persistence has been performed. The effect of delay and diffusion on the above system is studied. The role of diffusivity on stability and persistence criteria of the system has also been discussed.
EFFECT OF MATURATION AND GESTATION DELAYS IN A STAGE STRUCTURE PREDATOR PREY MODEL
Banerjee, Sandip,Mukhopadhyay, B.,Bhattacharyya, R. The Korean Society for Computational and Applied M 2010 Journal of applied mathematics & informatics Vol.28 No.5
In this paper, a stage-structured predator prey model (stage structure on prey) with two discrete time delays has been discussed. The two discrete time delays occur due to maturation delay and gestation delay. Linear stability analysis for both non-delay as well as with delays reveals that certain thresholds have to be maintained for coexistence. Numerical simulation shows that the system exhibits Hopf bifurcation, resulting in a stable limit cycle.
Analysis and Design of Energy and Slew Aware Subthreshold Clock Systems
Tolbert, J. R.,Xin Zhao,Sung Kyu Lim,Mukhopadhyay, S. IEEE 2011 IEEE transactions on computer-aided design of inte Vol.30 No.9
<P>In this paper, we analyze the effect of clock slew in subthreshold circuits. Specifically, we address the issue that variations in clock slew at the register control can cause serious timing violations. We show that clock slew variations can cause frequency targets to deviate by as much as 28% from the design goals. Based on these observations, we recognize the importance of clock slew control in subthreshold circuits. We propose a systematic approach to design the clock tree for subthreshold circuits to reduce the clock slew variations while minimizing the energy dissipation in the tree. The combined approach, including the wire sizing and dynamic nodal capacitance control, can achieve better slew control (and better timing control) at lower energy in subthreshold circuits.</P>