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Jutty Parthiban1,Oscar L. Alves,Komal Prasad Chandrachari,Premanand Ramani,Mehmet Zileli 대한척추신경외과학회 2019 Neurospine Vol.16 No.3
Cervical spondylotic myelopathy (CSM) is a common cause of adult spinal cord dysfunction. Although the therapeutic options for moderate to severe CSM patients have been established well, the existing guidelines for therapeutic decisions in mild cases of CSM are unclear. We present a review of literature on conservative treatment and surgery for CSM and suggest general recommendations applicable in various clinical presentations and in different geographic locations across the globe, with due considerations to available resources and locally prevalent practices.
Novel hybrids of drug with bioactive heterocycles for enhancing biological activity
Parthiban Valentina,Kaliappan Ilango,Muthu K. Kathiravan 대한약학회 2016 Archives of Pharmacal Research Vol.39 No.10
A novel series of aceclofenac hybridised with 1,2,4-triazolo-[3,4-b]-1,3,4-thiadiazoles were designed using molecular hybridization approach and synthesised 6a–j. The structural integrity was confirmed by analytical methods. The hybrid molecules were subjected to in vitro cytotoxic studies against four human cancer cell lines PA1, OAW-42, T47-D and MCF-7 by MTT assay method. The results indicate that the hybrid molecules bearing halogen on phenyl ring in 6th position of triazolo-thiadiazole exhibited significant cytotoxic activity. The test compounds were also screened for antifungal activity against two strains.
Parthiban Subramanian,고호철,김성훈,이재은,황예진,김빛샘,이윤정,Awraris Derbie Assefa,허온숙,노나영,성정숙,이주희,이호선,한범수 한국환경생물학회 2022 환경생물 : 환경생물학회지 Vol.40 No.4
Bacterial phytopathogen Pectobacterium causes soft rot disease in several vegetable crops globally, resulting in heavy agricultural losses at both the pre and post-harvest stages. The present work was carried out to screen Kimchi cabbage genetic resources conserved at the National Agrobiodiversity Center, Rural Development Administration, Korea, for resistance against the soft rot pathogen Pectobacterium carotovorum subsp. carotovorum KACC 21701 over a period of three years (from 2020 to 2022). Infection of the phytopathogen was carried out at four-leaf stage and for each accession, twenty-five plants per germplasm were infected with KACC 21701. Kimchi cabbage cultivars Wangmatbaechu, Seoulbaechu, and CR Kiyoshi were used as control. Seven-days post-infection, the Disease Index (DI) values were manually recorded from zero to four, zero matched perfectly heathy plants and four completely dead plants. The 682 accessions of Kimchi cabbage exhibited varying degrees of disease resistance to KACC 21701 and thirty accessions, exhibiting a DI≤2, were considered for replication studies. During the replication studies, four landrace germplasms (IT102883, IT120036, IT120044, and IT120048) and one cultivar (IT187919) were confirmed to be moderately susceptible to KACC 21701. Results of the preliminary screening as well as replication studies were documented for the all the 682 germplasms. Addition of such information to the passport data of stored germplasms might serve as potential bio-resource for future breeders and researchers to develop resistant varieties or study the mechanisms involved in resistance of plants to such phytopathogen.
Parthiban Subramanian,Manoharan Melvin Joe,임우종,홍보희,Sherlyn C. Tipayno,Venkatakrishnan Sivaraj Saravanan,유재홍,정종배,Tahera Sultana,사동민 한국토양비료학회 2011 한국토양비료학회지 Vol.44 No.4
Cold-adapted bacteria survive in extremely cold temperature conditions and exhibit various mechanisms of adaptation to sustain their regular metabolic functions. These adaptations include several physiological and metabolic changes that assist growth in a myriad of ways. Successfully sensing of the drop in temperature in these bacteria is followed by responses which include changes in the outer cell membrane to changes in the central nucleoid of the cell. Their survival is facilitated through many ways such as synthesis of cryoprotectants,cold acclimation proteins, cold shock proteins, RNA degradosomes, Antifreeze proteins and ice nucleators. Agricultural productivity in cereals and legumes under low temperature is influenced by several cold adopted bacteria including Pseudomonas, Acinetobacter, Burkholderia, Exiguobacterium, Pantoea, Rahnella,Rhodococcus and Serratia. They use plant growth promotion mechanisms including production of IAA,HCN, and ACC deaminase, phosphate solublization and biocontrol against plant pathogens such as Alternaria, Fusarium, Sclerotium, Rhizoctonia and Pythium.
Parthiban Pazhamalai(파자말라이 파르티반),Karthikeyan Krishnamoorthy(케이 카티케 이얀),Sindhuja Manoharan(마노하란 신드후자),Sang-Jae Kim(김상재) 대한기계학회 2021 대한기계학회 춘추학술대회 Vol.2021 No.4
Self-charging supercapacitor power cell (SCSPC) is one of the nascent areas of research for the surrogating to renewable energy resources. The prime obstacle in development SCSPC is the utilization of liquid electrolyte hinders the energy conversion efficiency which in turn creates a demand to explore and replace with new solid electrolytes for the SCSPCs. Herein, a new all solid state self-charging supercapacitor power cell (SCSPC) has been fabricated using Nafion as solid polyelectrolyte cum energy harvester and spray coated MoS2 quantum sheets (MoS2-QSs) as energy storage electrodes. The Nafion polyelectrolyte exhibits energy harvesting characteristics under mechanical deformation due to the change in ion concentration gradients between electrodes that leads to the generation of output voltage. The fabricated MoS2-Nafion-MoS2 SCSPC shows the self-charging characteristics upon various levels of compressive forces with a self-charging voltage of 243 mV. The self-charging mechanism of the fabricated MoS2-Nafion-MoS2 SCSPC is explained via piezo-ionic effect. These experimental findings have profound significance in the context of developing a potential all-in-one self-charging system.