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Nakano, Takafumi,Seo, Hong-Yul The Korean Society of Systematic Zoology 2014 Animal Systematics, Evolution and Diversity Vol.30 No.2
Specimens of the genus Orobdella Oka, 1895 from Korea, including various locations in the Korean Peninsula, were identified as Orobdella tsushimensis Nakano, 2011. Phylogenetic analyses using mitochondrial cytochrome oxidase subunit 1 (COI), ND1, $tRNA^{Cys}$, $tRNA^{Met}$, 12S rRNA, $tRNA^{val}$, and 16S rRNA markers show that the newly collected specimens form a monophyletic group with the known O. tsushimensis specimens. The genetic distance of COI of these specimens was in the range 0.4-6.6%. These results confirm that the newly collected specimens belong to O. tsushimensis. This is the first record of the genus Orobdella from the Korean Peninsula.
Akiyo Nakano,Ryuichi Nakano,Yuki Suzuki,Kyoichi Saito,Kei Kasahara,Shiro Endo,Hisakazu Yano 대한진단검사의학회 2018 Annals of Laboratory Medicine Vol.38 No.4
Dear Editor, Carbapenem-resistant Enterobacteriaceae have acquired carbapenemase genes [1], which differ substantially across countries [2]. Transferable carbapenemase IMP-type metallo-β-lactamases, particularly IMP-1 and IMP-6, are commonly identified in the clinical setting in Japan [3, 4] and exhibit different substrate specificity despite having a difference of only one amino acid (IMP-6: Ser214Gly). IMP-1 producers are more resistant to imipenem than to meropenem, whereas IMP-6 producers are more resistant to meropenem [5]. We previously found that the susceptibility rate of IMP-6-positive Escherichia coli was higher for imipenem than for meropenem [3]. Thus, IMP-6-producing isolates may be erroneously categorized as imipenem-susceptible, which could lead to treatment failure in patients.
Takafumi Nakano,Hong-Yul Seo 한국동물분류학회 2014 Animal Systematics, Evolution and Diversity Vol.30 No.2
Specimens of the genus Orobdella Oka, 1895 from Korea, including various locations in the Korean Peninsula, were identified as Orobdella tsushimensis Nakano, 2011. Phylogenetic analyses using mitochondrial cytochrome oxidase subunit 1 (COI), ND1, tRNACys, tRNAM<SUP>et</SUP>, 12S rRNA, tRNA<SUP>val</SUP>, and 16S rRNA markers show that the newly collected specimens form a monophyletic group with the known O. tsushimensis specimens. The genetic distance of COI of these specimens was in the range 0.4-6.6%. These results confirm that the newly collected specimens belong to O. tsushimensis. This is the first record of the genus Orobdella from the Korean Peninsula.
Masuo Nakano,Shiro Nakano,Hideo Takekoshi 한국식품영양과학회 2007 Journal of medicinal food Vol.10 No.1
In addition to meeting nutritional requirements, breast milk plays important roles in biodefense for nursing in-fants. Dioxins have been detected at high concentrations in breast milk, raising concerns about disorders in nursing infantscaused by breast milk containing dioxins in Japan. We analyzed dioxin levels in breast milk and maternal blood samples from35 pregnant women in Japan. We also measured immunoglobulin (Ig) A concentrations in breast milk and investigated cor-relations with dioxin concentrations. In addition, 18 of the 35 women took Chlorella pyrenoidosa(Chlorella) supplementsduring pregnancy, and the effects on dioxin and IgA concentrations in breast milk were investigated. Toxic equivalents weresignificantly lower in the breast milk of women taking Chlorellatablets than in the Control group (P. .003). These resultssuggest that Chlorellasupplementation by the mother may reduce transfer of dioxins to the child through breast milk. No sig-nificant correlation was identified between dioxin and IgA concentrations in breast milk in the Control group. It is unlikelythat normal levels of dioxin exposure via food have a remarkable influence on IgA in breast milk. IgA concentrations in breastmilk in the Chlorellagroup were significantly higher than in the Control group (P. .03). Increasing IgA levels in breast milkis considered to be effective for reducing the risk of infection in nursing infants. The present results suggest that Chlorellasupplementation not only reduces dioxin levels in breast milk, but may also have beneficial effects on nursing infants by in-creasing IgA levels in breast milk.
Hong-Yul Seo,Takafumi Nakano 한국응용곤충학회 2012 한국응용곤충학회 학술대회논문집 Vol.2012 No.05
New record of family of arhynchobdellida leeches (Orobdellidae) from Gageodo Island is presented. We have surveyed for land leeches in Korea from July to September in 2011 and found 1 species. This is Orobdella tsushimensis Nakano, 2011, reported for the first time in Korean Peninsula. This species gets the following characteristics: IV unianulate; 1/2+5 annuli between gonopores; bottle-shaped gastroporal duct; and epididymides in XVII–XIX. According to their morphological features, the diagnosis of O. tsushimensis is slightly emended. Phylogenetic analyses using mitochondrial COI, tRNACys, tRNAMet, 12SrDNA, tRNAVal and 16SrDNA markers show that the Orobdella specimen from Gageodo Isl. and O. tsushimensis from Tsushima Island, Japan, form a monophyletic clade and also confirm the identification of the Orobdella specimens from Gageodo Isl.
Brake Lining Can be Applied to Super High Speed Vehicle
Nakano Satoru,Maejima Takashi 한국분말야금학회 2006 한국분말야금학회 학술대회논문집 Vol.2006 No.1
A new material was developed to achieve improvement of heat durability, improvement of wear resistance, stability of friction coefficient and reduction in aggression to counterpart, because it is difficult to maintain braking properties by using currently available materials in the train wagons used for high-speed transportation. As a result, the new material showed a stable wear resistance even in the speed range of 350km/h, where improvement was also confirmed in reduction of aggression to counterpart material by more than approximately 10%. This development was adopted for the brake lining in the Taiwan High Speed Rail project.
Measurement of time-dependent CP asymmetries in B0→KS0ηγ decays
Nakano, H.,Ishikawa, A.,Sumisawa, K.,Yamamoto, H.,Adachi, I.,Aihara, H.,Al Said, S.,Asner, D. M.,Aulchenko, V.,Aushev, T.,Ayad, R.,Babu, V.,Badhrees, I.,Bansal, V.,Behera, P.,Beleñ,o, C.,Bhuyan, American Physical Society 2018 Physical Review D Vol.97 No.9
<P>We report a measurement of time-dependent CP violation parameters in B-0 -> K-S(0)eta gamma decays. The study is based on a data sample, containing 772 x 10(6)B(B)over-bar pairs, that was collected at the Upsilon(4S) resonance with the Belle detector at the KEKB asymmetric-energy e(+)e(-) collider. We obtain the CP violation parameters of S = -1.32 +/- 0.77(stat) +/- 0.36(syst) and A = -0.48 +/- 0.41(stat) f 0.07(syst) for the invariant mass of the K-S(0)eta system up to 2.1 GeV/c(2).</P>
Nakano, Ryoko World Association for Triple Helix and Future Stra 2018 Journal of Contemporary Eastern Asia Vol.17 No.1
Heritage has entered the center stage of public diplomacy in East Asia. Competition to claim and interpret memories of World War II in East Asia has driven campaigns to list heritage items with UNESCO. State and non-state actors aim to use heritage listings to present a particular view of the war and related history to domestic and international audiences. This paper highlights the role of heritage soft power in East Asia's "memory contests" by examining the promotion of dissonant modern heritage in UNESCO's heritage programs. It conceptualizes heritage designation as a soft power resource in East Asia and presents a conceptual framework for understanding the hegemonic competition over the "memory regime" that emerged from the structural change in East Asia's regional order. It then uses this framework to analyze the processes by which state and non-state actors promote and/or object to UNESCO recognition of their sites and documents as heritage of outstanding universal value or world significance. The elements of this process are illustrated with case studies of two very different pieces of heritage, Japan's "Sites of the Meiji Industrial Revolution" and China's "Documents of Nanjing Massacre," which were enshrined as significant world heritage in 2015. While state and non-state actors in East Asia are increasingly recognizing the utility of heritage as a soft power resource for advancing specific historical narratives to an international audience, a backlash movement from civil society groups and governments in other countries prevents a purely unilateral interpretation. As a result, the utility of heritage soft power in this context must be significantly qualified.
<sup>123</sup>I-Labeled oxLDL Is Widely Distributed Throughout the Whole Body in Mice
Nakano, Atushi,Kawashima, Hidekazu,Miyake, Yoshinori,Zeniya, Tsutomu,Yamamoto, Akihide,Koshino, Kazuhiro,Temma, Takashi,Fukuda, Tetsuya,Fujita, Yoshiko,Kakino, Akemi,Kanaya, Shigehiko,Sawamura, Tatsuy 대한핵의학회 2018 핵의학 분자영상 Vol.52 No.2
Purpose Oxidized low-density lipoprotein (oxLDL) plays a key role in endothelial dysfunction, vascular inflammation, and atherogenesis. The aim of this study was to assess blood clearance and in vivo kinetics of radiolabeled oxLDL in mice. Methods We synthesized $^{123}I-oxLDL$ by the iodine monochloride method, and performed an uptake study in CHO cells transfected with lectin-like oxLDL receptor-1 (LOX-1). In addition, we evaluated the consistency between the $^{123}I-oxLDL$ autoradiogram and the fluorescence image of DiI-oxLDL after intravenous injection for both spleen and liver. Whole-body dynamic planar images were acquired 10 min post injection of $^{123}I-oxLDL$ to generate regional time-activity curves (TACs) of the liver, heart, lungs, kidney, head, and abdomen. Regional radioactivity for those excised tissues as well as the bladder, stomach, gut, and thyroid were assessed using a gamma counter, yielding percent injected dose (%ID) and dose uptake ratio (DUR). The presence of $^{123}I-oxLDL$ in serum was assessed by radio-HPLC. Results The cellular uptakes of $^{123}I-oxLDL$ were identical to those of DiI-oxLDL, and autoradiograms and fluorescence images also exhibited consistent distributions. TACs after injection of $^{123}I-oxLDL$ demonstrated extremely fast kinetics. The radioactivity uptake at 10 min post-injection was highest in the liver ($40.8{\pm}2.4%$ ID). Notably, radioactivity uptake was equivalent throughout the rest of the body ($39.4{\pm}2.7%$ ID). HPLC analysis revealed no remaining $^{123}I-oxLDL$ or its metabolites in the blood. Conclusion $^{123}I-oxLDL$ was widely distributed not only in the liver, but also throughout the whole body, providing insight into the pathophysiological effects of oxLDL.