http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Clinical investigation of patients with jaw deformity with comorbidities
Kiyohiro Kasahara,Teruhide Hoshino,Kei Sugiura,Yuki Tanimoto,Masahide Koyachi,Masae Yamamoto,Keisuke Sugahara,Masayuki Takano,Akira Katakura 대한악안면성형재건외과학회 2022 Maxillofacial Plastic Reconstructive Surgery Vol.44 No.-
Background: With improvements in the safety and stability of surgeries, the number of orthognathic surgeries isincreasing. Most patients who undergo orthognathic surgeries are younger, and the number of orthognathic surgeriesfor patients with comorbidities is also increasing. We report a survey and clinical investigation of patients withcomorbidities who underwent orthognathic surgeries at our department to improve the safety of orthognathicsurgery. Results: The participants included 296 men and 712 women, with a mean age of 28 years (13?19 years, n=144;20?29 years, n=483; 30?39 years, n=236; 40?49 years, n=102; 50?59 years, n=39; ≥60 years, n=4). In total, 347patients underwent one-stage Le Fort type I osteotomy and sagittal split ramus osteotomy (SSRO), 243 underwentSSRO, 287 underwent plate removal, 126 underwent genioplasty and plate removal, and five underwent othersurgeries. In total, 529 patients had comorbidities (52%), including allergic diseases (n=220, 33%), respiratory diseases(n=107, 16%), neurologic and psychiatric diseases (n=69, 10%), gynecologic diseases (n=28, 4%), hematologicdiseases (n=27, 4%), cardiovascular diseases (n=24, 4%), digestive diseases (n=22, 3%), metabolic and endocrinediseases (n=18, 3%), spinal diseases (n=11, 2%), ophthalmologic diseases (n=11, 2%), renal and urological diseases(n=9, 1%), and other diseases (n=117, 18%). Among the patients with comorbidities, 11 with hemorrhagic diatheses(hemophilia and von Willebrand disease), arrhythmia (atrioventricular block), psychiatric disease (adjustment disorder),and metabolic disease (diabetes) required cautious perioperative management. The patient with hemophilia wasmanaged with regular low-dose recombinant factor VIII replacement therapy, and the patient with type I diabetesmellitus was administered continuous insulin infusion and sliding-scale insulin therapy; both patients had an uneventfulcourse. Conclusions: The study findings suggest that with the increase in orthognathic surgeries, oral and maxillofacialsurgeons should adequately manage cases requiring cautious perioperative control and highlight the importance ofpreoperative screening. Despite the well-established safety and postoperative stability of orthognathic surgeries, oralsurgeons should adopt appropriate additional preventive measures for patients with comorbidities.
Synovial tissue morphology of the cricoarytenoid joint in the elderly
Sakura Katsumura,Masahito Yamamoto,Kei Kitamura,Masaaki Kasahara,Yukio Katori,Shin-ichi Abe 대한해부학회 2016 Anatomy & Cell Biology Vol.49 No.1
We compared the age-related morphology of the cricothyroid (CT) joint with that of the cricoarytenoid (CA) joint using 18 specimens from elderly cadavers in terms of their elastic fiber contents as well as the cells composing the joint capsule and synovial tissues. In contrast to an almost flat-flat interface in the CT joint, the CA joint was similar to a saddle joint. The CA joint capsule was thin and contained few elastic fibers, and in contrast to the CT joint, external fibrous tissues were not exposed to the joint cavity, there being no injury to the CA joint capsule. The lateral and posterior aspects of the CA joint were covered by the lateral and posterior CA muscles, respectively, and the fascia of the latter muscle was sometimes thick with abundant elastic fibers. However, due to possible muscle degeneration, loose connective tissue was often interposed between the fascia and the capsule. The medial and anterior aspects of the CA joint faced loose tissue that was continuous with the laryngeal submucosal tissue. Therefore, in contrast to the CT joint, a definite supporting ligament was usually absent in the CA joint. Synovial folds were always seen in the CA joint, comprising a short triangular mass on the posterior side and long laminar folds on the anterior side. The synovial folds usually contained multiple capillaries and a few CD68-positive macrophages. High congruity of the CA joint surfaces as well as strong muscle support to the arytenoid cartilage appeared to provide the specific synovial morphology.
Sunki Rhee,Masahito Yamamoto,Kei Kitamura,Kasahara Masaaki,Yukio Katori,Gen Murakami,Shin ichi Abe 대한해부학회 2016 Anatomy & Cell Biology Vol.49 No.3
Macrophages play an important role in aging-related muscle atrophy (i.e., sarcopenia). We examined macrophage density in six striated muscles (cricopharyngeus muscle, posterior cricoarytenoideus muscle, genioglossus muscle, masseter muscle, infraspinatus muscle, and external anal sphincter). We examined 14 donated male cadavers and utilized CD68 immunohistochemistry to clarify macrophage density in muscles. The numbers of macrophages per striated muscle fiber in the larynx and pharynx (0.34 and 0.31) were 5-6 times greater than those in the tongue, shoulder, and anus (0.05-0.07) with high statistical significance. Thick muscle fibers over 80 μm in diameter were seen in the pharynx, larynx, and anal sphincter of two limited specimens. Conversely, in the other sites or specimens, muscle fibers were thinner than 50 μm. We did not find any multinuclear muscle cells suggestive of regeneration. At the beginning of the study, we suspected that mucosal macrophages might have invaded into the muscle layer of the larynx and pharynx, but we found no evidence of inflammation in the mucosa. Likewise, the internal anal sphincter (a smooth muscle layer near the mucosa) usually contained fewer macrophages than the external sphincter. The present result suggest that, in elderly men, thinning and death of striated muscle fibers occur more frequently in the larynx and pharynx than in other parts of the body.
지각 구조 연구에서 광각 탄성파 자료를 위한 대화식 분석 방법들
등강강,립원순삼,촌뢰규,망월공광,김전의행,Fujie, Gou,Kasahara, Junzo,Murase, Kei,Mochizuki, Kimihiro,Kaneda, Yoshiyuki Korean Society of Earth and Exploration Geophysici 2008 지구물리와 물리탐사 Vol.11 No.1
The analysis of wide-angle seismic reflection and refraction data plays an important role in lithospheric-scale crustal structure study. However, it is extremely difficult to develop an appropriate velocity structure model directly from the observed data, and we have to improve the structure model step by step, because the crustal structure analysis is an intrinsically non-linear problem. There are several subjective processes in wide-angle crustal structure modelling, such as phase identification and trial-and-error forward modelling. Because these subjective processes in wide-angle data analysis reduce the uniqueness and credibility of the resultant models, it is important to reduce subjectivity in the analysis procedure. From this point of view, we describe two software tools, PASTEUP and MODELING, to be used for developing crustal structure models. PASTEUP is an interactive application that facilitates the plotting of record sections, analysis of wide-angle seismic data, and picking of phases. PASTEUP is equipped with various filters and analysis functions to enhance signal-to-noise ratio and to help phase identification. MODELING is an interactive application for editing velocity models, and ray-tracing. Synthetic traveltimes computed by the MODELING application can be directly compared with the observed waveforms in the PASTEUP application. This reduces subjectivity in crustal structure modelling because traveltime picking, which is one of the most subjective process in the crustal structure analysis, is not required. MODELING can convert an editable layered structure model into two-way traveltimes which can be compared with time-sections of Multi Channel Seismic (MCS) reflection data. Direct comparison between the structure model of wide-angle data with the reflection data will give the model more credibility. In addition, both PASTEUP and MODELING are efficient tools for handling a large dataset. These software tools help us develop more plausible lithospheric-scale structure models using wide-angle seismic data.
Kubota, Ryuji,Nishiyama, Eiichiro,Murase, Kei,Kasahara, Junzo Korean Society of Earth and Exploration Geophysici 2009 지구물리와 물리탐사 Vol.12 No.1
관측된 파형의 특성들을 해석하여 굴절파와 광각으로 도달한 반사파를 분석하면 결과물로 얻어지는 지각구조 모델의 신뢰도를 향상시킬 수 있으며, 균일한 격자상의 그래프 이론에 기반한 파면법은 복잡한 구조에서도 주시와 파선경로를 효과적으로 계산할 수 있으나, 기본적으로 초동만을 이용하게 되는 단점이 있다. 이번 연구에서는 초동뿐만 아니라 후기 시간대에 도달하는 반사파와 굴절파 및 변환된 P파와 5파의 주시와 파선경로를 계산하기 위하여 다층 모델상에서 표현되는 slowness network 노드에 기반한 수정 파면법을 이용하는 새로운 알고리즘을 개발하였다. 새로운 알고리즘을 통해 모호면의 형태와 변환된 P파와 S파의 위상을 획득하기 위하여 후기 시간대의 Pg파, Pn파 이후에 들어오는 강한신호의 파, 모호면에서 중첩된 PmP를 분석하였다. 제안된 알고리즘의 효용성을 검증하기 위하여 해양-대륙의 전이대와 해령 및 해산에 러한 모델링 연구를 수행하였으며, 2차원 유한차분법을 이용한 수치모형을 통해 그 효용성을 확인하였다. 초동 주시만을 해석에 사용할 경우 대륙-해양 전이대와 해령 및 해산과 같은 모델에서 획득되는 도달파들과 파선경로들의 특성이 각기 다르게 나타나 많은 해석상의 오류가 발생할 수 있는 위험성이 있기 때문에 제안된 기법을 통해 효과적인 해석을 수행할 수 있을 것이다.
Akiyo Nakano,Ryuichi Nakano,Yuki Suzuki,Kyoichi Saito,Kei Kasahara,Shiro Endo,Hisakazu Yano 대한진단검사의학회 2018 Annals of Laboratory Medicine Vol.38 No.4
Dear Editor, Carbapenem-resistant Enterobacteriaceae have acquired carbapenemase genes [1], which differ substantially across countries [2]. Transferable carbapenemase IMP-type metallo-β-lactamases, particularly IMP-1 and IMP-6, are commonly identified in the clinical setting in Japan [3, 4] and exhibit different substrate specificity despite having a difference of only one amino acid (IMP-6: Ser214Gly). IMP-1 producers are more resistant to imipenem than to meropenem, whereas IMP-6 producers are more resistant to meropenem [5]. We previously found that the susceptibility rate of IMP-6-positive Escherichia coli was higher for imipenem than for meropenem [3]. Thus, IMP-6-producing isolates may be erroneously categorized as imipenem-susceptible, which could lead to treatment failure in patients.
Yoshihiko Ogawa,Masatoshi Sato,Takaya Yamashita,Ryuichi Nakano,Satoshi Mochizuki,Kei Kasahara,Hisakazu Yano,Keiichi Mikasa 대한진단검사의학회 2018 Annals of Laboratory Medicine Vol.38 No.1
Dear Editor, Intraabdominal infections are well-known sources of polymicrobial bacteremia [1, 2]. Anaerobes such as Bacteroides spp. and Clostridium spp. account for 30–50% of these cases [2-4]. However, a significant proportion of anaerobes remain unidentified. Lee et al [5] reported that the conventional identification method correctly identifies anaerobic bacteria only 79.4% to the genus level and 60.1% to the species level. Here, we report a case of polymicrobial bacteremia with three anaerobes in a patient with peritonitis following intestinal perforation. The anaerobes included Butyricimonas virosa and Brachyspira pilosicoli, both of which are difficult to identify by the conventional identification method