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염명헌,정완호 한국교원대학교 환경과학연구소 1994 환경연구논문집 Vol.- No.2
This result showed that the middle school students' response for the environment condition was highly negative. The major findings of this study are as follows. 1. Students would become to know the environmental pollution through reading of newspapers and TV rather than school education. 2. Students' response for air and water pollution was seriously accepted in city areas than in country areas, and in large cities than in small cities. 3. Students' response for air pollution showed that the quality of air was getting worse and major factor of air pollution was the exhausts of automobiles. 4. It showed that students' concern for water pollution was increased and water pollution was being accelerated by the increase of domestic and industrial sewages, the overuse of the agricultural chemicals, the eutrophication and acid rain. 5. Students thought that soil pollution was mainly due to factory sewage, life sewage, heavy metal and agricultural medicines and so on. But now they think it is due to the degenerated and inseparable things such as used vinyle for farm and plastics. 6. Most students thought of the pollution of our country as serious. But they thought it could be removed if we tried to get rid of the pollution. 7. Now students' consciousness to protect the nature took an active interest turn and was strong. Putting these various findings together, I suggested that the efforts to turn students' affirmative consciousness for the environment and a powerful plan by the nation to take off pollution should be needed. Also the education to enforce the environment preservation had to be needed.
증례보고 : 사지마비환자에서 기관절개술 시 근이완제의 사용없이 후두마스크를 이용한 정맥마취
염승훈 ( Seung Hun Yeom ),정상호 ( Sang Ho Jeong ),하명화 ( Myung Hwa Ha ),송남원 ( Nam Won Song ) 대한마취과학회 2008 Korean Journal of Anesthesiology Vol.55 No.6
Quadriplegia is a serious or complete loss of motor function of all four limbs that is commonly caused by spinal cord injuries secondary to damage to the cervical spine. In this situation, there is a higher risk of pneumonia due to paralysis of the respiratory muscles. Tracheostomy is preferred over endotracheal intubation for the effective elimination of sticky bronchial secretion. The safest technique for a tracheostomy is to carry it out under general anesthesia with endotracheal intubation. However, endotracheal intubation may be difficult and cause other complications in patients with laryngotracheal stenosis caused by repeated tracheostomy and a limitation of neck movement as a result of the fixation of the cervical vertebral bodies due to the cervical spine fracture. We report a case of a tracheostomy performed sucessfully under intravenous anesthesia using a laryngeal mask airway without muscle relaxants in a patient with quadriplegia caused by a cervical spine injury. (Korean J Anesthesiol 2008; 55: 747~51)
조가영 ( Ga Young Cho ),염명훈 ( Myung Hun Yeom ),박성일 ( Seong Il Park ),조준철 ( Jun Cheol Cho ),유선혜 ( Sun Hye Yu ),최윤정 ( Yoon Jung Choi ),김종일 ( Jong Il Kim ) 대한화장품학회 2013 대한화장품학회지 Vol.39 No.3
본 연구의 목표는 한의학을 기초로 한 새로운 평가 방법을 이용하여 한방화장품의 효과를 분석하고자 하는 것이다. 한의학에서는 얼굴과 피부에 나타나는 현상을 분석하는 것이 환자의 질병과 체질을 예측하는 중요한 방법이었다. 내부 장기의 상태를 얼굴에 발현되는 증상과 피부를 통해 진단하는 방법을 한의학의 진단체계에서는 ‘망진(望診)’이라 한다. 이에 저자들은 지난 5년간 인삼농축크림을 사용한 피검자군 여성 11명과 대조군여성 11명을 대상으로 한의사 3인의 망진 평가와 비침습적인 피부 실측 과정(non-invasive skin bio-engineering)을 병행하여 두 그룹 간의 피부 상태를 비교하여 유의한 결과를 얻었기에 이를 보고하는 바이다. 총 17항목의 망진 평가에서는 7개 항목에서 인삼농축크림 장기사용군이 대조군에 비하여 통계적으로 유의하게 우수한 결과를 보였으며 7가지 피부 측정항목에서는 유분, 거칠기, 색소침착 면적과 눈가 주름 깊이에서 인삼농축 크림 장기사용군이 대조군에 비해 우수한 결과를 보였다. 본 실험을 통해 인삼농축크림의 장기사용이 피부에 긍정적인 영향을 줌을 확인하였으며, 또한 한의학적인 진단법과 현대기기를 이용한 피부 계측 방법을 융합하여 한방화장품의 특성을 살린 신규 평가 방법을 제안하고자 하였다. The aim of this study is to evaluate the effect of cosmetic products containing concentrated ginseng using novel methods based on Traditional Korean medicine (TKM). In TKM, inspection of facial skin was an important method to diagnose symptoms and body condition of patients. Doctors in oriental medicine examined a patient as observing symptoms on the face and skin related to inner organs. This was called “mang-jin. In this study, eleven female, who have been using the cosmetic products containing concentrated ginseng for the last 5 years, and eleven healthy controls, who have never used the same product, were recruited. Three doctors in oriental medicine evaluated 17 inspection factors on facial skin. And 7 non-invasive skin bioengineering factors were assessed by various instruments at the same time. In results, 7 factors of the inspection were better in using the product than in controls. And sebum, roughness, pigmentation and wrinkle depth were significantly lower in using the product than in controls. So, this results propose that the cosmetic product containing concentrated ginseng has a good anti-aging effect on skin. And it is suggested that the novel evaluation method combined, Traditional Korean medicine and modern bioengineering technique, has to be developed for holistic concept of Hanbang cosmetics.
Sun, Yan-Lin,Wang, Dong,Yeom, Myung-Hun,Kim, Duck-Hee,Kim, Han-Gon,Hong, Soon-Kwan The Korean Society of Plant Biotechnology 2011 식물생명공학회지 Vol.38 No.4
The medicinal herb Oldenlandia diffusa is known as a folk medicine for the treatment of hepatitis, sore throat, appendicitis, malignant tumors and urethral infection in Southern China and Korea. Another species O. corymbosa, is also used for the therapy of the similar conditions, however, only O. diffusa is referred to the medicinal herb by Chinese Pharmacopoeia. Due to their similar morphology, O. diffusa and O. corymbosa are often misidentified. To easily identify O. diffusa from O. corymbosa, the phylogenetic utility of nuclear ribosomal DNA (nrDNA) internal transcribed spacers (ITS) were investigated among different O. diffusa and O. corymbosa populations in Korea. The nrDNA ITS sequence of O. diffusa contained 791 bp, with GenBank accession number of JF837601-JF837602. The nrDNA ITS sequence of O. corymbosa was 785-786 bp, with GenBank accession number of JF837603-JF837611. The results showed that there are some certain divergences in the ITS region sequence between both species, even among different populations of the same species. Particularly, O. corymbosa ST-4 population showed the highest dissimilarity of the ITS region sequence with other nine populations of O. corymbosa and two populations of O. diffusa. This consequence makes us further understand the molecular diversification between O. corymbosa and O. diffusa, and help to promote the correct use and safety.
Yan-Lin Sun,Dong Wang,Myung-Hun Yeom,Duck-Hee Kim,Han-Gon Kim,홍순관 한국식물생명공학회 2011 식물생명공학회지 Vol.38 No.4
The medicinal herb Oldenlandia diffusa is known as a folk medicine for the treatment of hepatitis, sore throat, appendicitis, malignant tumors and urethral infection in Southern China and Korea. Another species O. corymbosa,is also used for the therapy of the similar conditions,however, only O. diffusa is referred to the medicinal herb by Chinese Pharmacopoeia. Due to their similar morphology,O. diffusa and O. corymbosa are often misidentified. To easily identify O. diffusa from O. corymbosa, the phylogenetic utility of nuclear ribosomal DNA (nrDNA) internal transcribed spacers (ITS) were investigated among different O. diffusa and O. corymbosa populations in Korea. The nrDNA ITS sequence of O. diffusa contained 791 bp, with GenBank accession number of JF837601-JF837602. The nrDNA ITS sequence of O. corymbosa was 785-786 bp, with GenBank accession number of JF837603-JF837611. The results showed that there are some certain divergences in the ITS region sequence between both species, even among different populations of the same species. Particularly, O. corymbosa ST-4 population showed the highest dissimilarity of the ITS region sequence with other nine populations of O. corymbosa and two populations of O. diffusa. This consequence makes us further understand the molecular diversification between O. corymbosa and O. diffusa, and help to promote the correct use and safety.
Ginsenoside F1 Modulates Cellular Responses of Skin Melanoma Cells
Dae Sung Yoo,Ho Sik Rho,Yong Gyu Lee,Myung Hun Yeom,Duck Hee Kim,Sang-Jin Lee,Sungyoul Hong,Jaehwi Lee,Jae Youl Cho 고려인삼학회 2011 Journal of Ginseng Research Vol.35 No.1
Ginsenoside (G)-F1 is an enzymatic metabolite generated from G-Rg1. Although this metabolite has been reported to suppress platelet aggregation and to reduce gap junction-mediated intercellular communication, the modulatory activity of G-F1 on the functional role of skin-derived cells has not yet been elucidated. In this study, we evaluated the regulatory role of G-F1 on the cellular responses of B16 melanoma cells. G-F1 strongly suppressed the proliferation of B16 cells up to 60% at 200 μg/mL, while only diminishing the viability of HEK293 cells up to 30%. Furthermore, G-F1 remarkably induced morphological change and clustering of B16 melanoma cells. The melanin production of B16 cells was also significantly blocked by G-F1 up to 70%. Interestingly, intracellular signaling events involved in cell proliferation, migration, and morphological change were up-regulated at 1 h incubation but down-regulated at 12 h. Therefore, our results suggest that G-F1 can be applied as a novel anti?skin cancer drug with anti-proliferative and anti-migration features.
조가영,김지연,염명훈,조준철,김윤범,Cho, Ga-Young,Kim, Jee-Yeun,Yeom, Myung-Hun,Cho, Jun-Cheol,Kim, Yoon-Bum 대한한방안이비인후피부과학회 2012 한방안이비인후피부과학회지 Vol.25 No.3
Objectives : We investigated the skin properties on the periorbital region and cheek of Korean female according to age pattern by 7year based on Sang Go Cheun Jin Ron (上古天眞論) in So Moon (素問,) Methods : 49 Korean females, aged 21-56 years ($39.54{\pm}10.04$ years) were participated in this study. We measured the skin properties of periorbital region and cheek with SkinTouch (Amorepacific, Korea). Skin moisture, sebum, elasticity, lightness, roughness, area of wrinkle, depth of wrinkle were assessed. Results : Differences were noticed depending on the site and age. The level of moisture was higher on the eyelid than crow's feet. The level of lightness and elasticity were lower on the periorbital region than cheek. Skin lightness was highest on group1(under 28y) and lowest on group5(over 49y). Skin roughness was highest on group1(under 28y) and lowest on group4(over 42y under 49y). The level of wrinkle are was lowest on group1(under 28y) and highest on group 5(over49y). The level of wrinkle depth was lowest on group1(under 28y) and highest on group 4(over 42y under 49y). Conclusion : Unique aging pattern by 7 years of female is reflected to diverse skin properties of eyes. It can be possible to apply the theory on Sang Go Cheun Jin Ron (上古天眞論) to practical use in dermatology and cosmetic.