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非行少年의 性犯罪에 관한 硏究 : 多要因的 接近方法 a multiple factor approach
兪碩鎭,盧明來 순천향대학교 1982 논문집 Vol.5 No.3
In the preceding study we have investigated and analyzed the differences in the intellectual levels and in MMPI profiles of the sexual criminals. In this study we will comprehensively invesitigate the factors influencing the sexual crimes in the juvenile delinquents. The subjects in this study were 211 sexual criminals who were institutionalized to the Seoul Juvenile Detention & Classification Center. This sample was investigated and interviewed by clinical psychologist & psychiatrist. The major findings investigated from this study were as follows: 1) The age of sexual criminals or rape victims is typically from 16 to 18 & their occupations were students & factory workers. 2) 26.54% of the sexual criminals (65.22% of the child group who were committed sexual assaults under the 13s & 21.81% of the girl-adult group who were committed sexual assaults Over the 13s) revealed psychiatric problems. 3) 28.44% of the sexual criminals were in drunken state at the time of their act. 4) Group or gang rape (involving two or more rapists) were estimated to comprise up to 80% of all sexual criminal cases. 5) 82.46% of the sexual criminals were in close relationship with the juvenile delinquents 6) The sexual experiences of the sexual criminals(41.23%) were more than those of general school boys(15.1%) and the age of victims is older than that of rapist. 7) The socio-economic classes to which the sexual criminals belongs were the low or low-middle socio-economic classess. 8) 40.26% of the sexual criminals had no sisters. 9) 15.64% of the sexual criminals don't have their parent and these findings showed no significant differences from that of the normal or the other group. 10) The sexual crimes have taken place in the deserted areas (41.13%), the around dwelling houses(20.38%) & the interior of the house(16.59%). 11) 70.62% of the sexual crime occured from between 7 p.m. to 12 p.m 12) The occurrence of rape has nothing to do with the month or the season.
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유산양 유방염에 대한 Chitosan 약침의 치료 효과
황수현,서진석,김덕환,김명철,신상태,전무형,南三郞,김영찬,이우근,표수일 충남대학교 수의과대학 동물의과학연구소 1999 動物醫科學硏究誌 Vol.7 No.-
To improve the therapeutic method for mastitis, treatment effect of chitosan pharmacopuncture was examined in three milking goats(A,B and C). Mastitis was artificially induced in two milking goats(A and B) and one goat(C) was naturally infected case with mastitis. The acupoint used was Yang-Ming and chitosan suspensions(provided from Tottory University, Japan: 30㎎ of chitosan/㎖)were injected to the acupoint with 5㎖/time for 3 days, respectively. As for the change of somatic cells in milk along with chitosan pharmacopuncture, they showed a decreasing tendency after increase on the 3rd day in all udders of B. In addition, as for the change of total leukocyte counts of peripheral blood with chitosan pharmacopuncture, they showed a decreasing tendency after increase on the 3rd day in B and C except A which showed a increasing tendency until on the 7th day. In the change of neutrophil/lymphocyte(N/L) ratio, increasing tendency was seen in A and C but increasing tendency after slight decrease was observed in B. Further, in the change of serum total protein and A/G ratio, serum total protein content was decreased after slightly increase on the 3rd day in A, and they were decreased after increase until on the 7th day in B and C, respectively. As for the change of A/G ratio, different pattern increasing tendency was shown in A, B and C.
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오은영,황이삭,문재석,조선미,윤석남,이명훈 대한생물치료정신의학회 2003 생물치료정신의학 Vol.9 No.2
Objective The purpose of this study was to examine the regional cerebral blood-flow (CBF) difference between boys with pure ACHD and normal controls before and after methylphenidate treatment, and also we examined the association between rCBF changes and cognitive characteristics of boys with pure ADHD before and after methylphenidate treatment. Methods The rCBF of 5 boys with pure AOHD and 5 control boys were examined by Tc-99m ECD brain SFECT and cognitive characteristics by ADS and every 5 ADHD boys took MPH for 12 to 16 weeks After that all ADHD boys took Tc-99m ECD brain SPECT and checked ADS again rCBF difference and changes before and after MPH treatment were quantified and analyzed by using SPM And associations between types of cognitive changes measured by ADS and rCBF changes were examined and quantitative associations between them were also analyzed by using Pearson's coefficient correlation. Results 1) Before MPH treatment, rCBF of ADHD boys were significantly decreased in left orbitofrontal area and left caudate nucleus compared to normal controls 2) After MPH treatment. rCBF of the same regions were significantly increased. 3) There was positive correlation between the degree of commission error(impulsivity disinhibition) among the ADS variables and the degree of blood-flow decrease in above two areas before MPH treatment but after MPH treatment, only with the degree of rC3F increase in Lt orbitofrontal area. Conclusion : These results suggest that the pathophysiology of impulsivity of disinhibition of the characteristic symploms of AOHD boys IS associated with hypoactivties of left orbibfrontal area and left caudate nucleus, and MPH pharmacodynamics in ADHD boys is associated to their actions on these two areas.
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Study of CO Oxidation on Well-Characterized Pt-Ru/C Electrocatalysts Having Different Composition
Min, Myoung-Ki,Kim, Joo-Hoon,Kim, Ha-Suck Korean Chemical Society 2010 Bulletin of the Korean Chemical Society Vol.31 No.1
In this paper, we characterized bimetallic Pt-Ru/C alloy catalysts having four different compositions and compared the catalytic activities of the prepared alloys for CO oxidation. ICP-AES, EDS, XRD, TEM, and XAS were used to investigate the composition, degree of alloying, particle size, and electronic structure of the prepared Pt-Ru/C catalysts. Those results indicated the synthesis of the alloy catalysts with intended composition and uniform size. The electrochemical study of the characterized alloys showed higher catalytic activity for CO oxidation than that of the commercial Pt/C (E-TEK, Inc., 20 wt %) catalyst. Especially, it was shown that the alloy catalyst with Ru composition of 50 atomic % gave the highest catalytic activity for CO oxidation.
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이석희(Suck?Hee Lee),신진화(Jin?Hwa Shin),구명오(Myoung?O Koo),정은실(Eun?Sil Jung),전경임(Geong?Im Jeon),박은주(Eunju Park),박해룡(Hae?Ryong Park),이승철(Seung?Cheol Lee) 한국식품영양과학회 2007 한국식품영양과학회지 Vol.36 No.10
생 아귀와 마른 아귀를 부위별로 구분하여 여러 용매를 이용하여 추출물을 제조한 후 항산화 활성과 항유전독성 활성을 조사하였다. 아귀의 수분함량을 조사한 결과 생 아귀의 껍질, 살, 위 부분은 모두 85% 이상의 수분을 함유하였으나, 간은 53.5%이었다. 마른 아귀의 경우 껍질 부위가 생것의 경우보다 21.2%가 낮은 66.7%이었고, 살 부위는 생것의 경우보다 7.9% 낮은 77.7%이었다. 추출수율은 마른 아귀 껍질분쇄물 100 g으로부터 물을 이용하여 추출하였을 때 6.76 g의 추출물이 얻어진 경우로 이 조건이 가장 수율이 높았다. 항산화 활성을 1, 20, 40 ㎎/mL의 농도에서 측정하였을 때 라디칼 소거능, 환원력은 각각 농도에 의존하여 결과값이 향상되었으며, 라디칼 소거능에서는 생 아귀의 껍질, 살 및 위 부분과 말린 아귀의 껍질, 살에서는 모두 아세톤 추출물에서 가장 높은 활성을 보였다. 한편, 생 아귀의 간부위에서는 메탄올 추출물과 물 추출물에서 높은 활성을 보였고, 에탄올과 아세톤 추출물에서도 비교적 높은 활성을 보였다. 환원력에서는 껍질, 살 및 위 부분에서 아세톤 추출물에서 가장 높은 활성을 보였다. 생 아귀의 간부위에서는 모든 추출물에서 높은 환원력을 보였다. 그리고 다양한 아귀 추출물을 50 ㎍/mL의 농도로 백혈구에 처리한 후 H₂O₂ 200 ㎛의 농도로 DNA 손상을 유도한 결과 손상된 DNA tail 부분의 DNA 함량을 측정한 % fluorescence in tail이 위의 메탄올, 아세톤 및 물 추출물을 제외하고는 각 부위의 모든 추출물에서 H₂O₂ 처리 양성대조구인 32.1±6.7%에 비해 유의적으로 감소하였다. 한편, 추출용매별로 아귀 각 부위의 항유전독성 효과를 비교한 결과 메탄올, 에탄올, 물 추출물은 부위에 따른 항유전독성효과의 차이가 없었으나, 아세톤 추출물의 경우 마른 살이 위에 비해 DNA 손상정도가 유의적으로 낮았다. 따라서 이번 연구결과는 생리활성 물질을 탐색함에 있어서 해양생물이 중요한 천연자원이 될 수 있다는 가능성을 확인할 수 있었다. Antioxidant activities of extracts from anglerfish (Lophiius litulon) were evaluated. Each part of fresh (skin, flesh, stomach, and liver) or dried (skin and flesh) anglerfish was extracted by four different solvents (methanol, ethanol, acetone, and distilled water). Antioxidant activities of the extracts were determined by radical scavenging activity (RSA) and reducing power (RP). Relatively higher RSA and RP were found in methanol and water extract of fresh anglerfish liver. Antigenotoxic effect of the extracts, which was measured by Comet assay, was shown in most of the extracts except methanol, acetone and distilled water extracts of fresh stomach sample. These results indicated that antioxidant and antigenotoxic properties of extracts from angler fish were variable depending on parts, solvent, and/or physicochemical state. The appropriate extraction process could provide some valuable bioactive materials from anglerfish.
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우리나라 사문암토양에서 생육하는 참억새에서의 중금속 거동
김명희,민일식,송석환 中部大學校 自然科學硏究所 1999 自然科學硏究論文集 Vol.8 No.1
우리나라 남한에 분포하는 사문암 지역(광천, 홍성, 백동, 대흥, 유구, 안동, 울산)의 상부토양과 참억새 시료의 중금속 함량을 분석하여 사문암 토양에서의 식물에 의한 중금속 원소의 흡수관계를 조사하였다. 사문암 토양에서 생육하는 참억새의 Ni, Cr, Co 농도는 각각 87-510 ppm, 81-745 ppm, 3.8-44 ppm 였다. 사문암 토양에서 생육하는 참억새에 의하여 흡수된 중금속간의 상호관계에서는 Ni은 Co, Cr, Zn 및 Fe와, Co는 Cr, Zn 및 Fe와 Cr은 Fe와 Zn은 Mo 및 Fe와 상관관계를 보였다. 특히 Ni-Fe, Ni-Co, Co-Fe 간에 높은 상관관계를 나타내었다. 토양의 중금속 함량은 참억새에서보다 높고 참억새 뿌리의 농도가 지상부보다 높았으며 원소별로 토양과 참억새에 의한 원소 함량간에는 Mo를 제외하고는 토양과 식물체 농도간에 상관관계가 나타나지 않았다. This study was conducted to investigate for the behavior of heavy metal in top soil and M. sinensis form the serpentine area(Kwangcheon, Hongseong, Baekdong, Yoogoo, Andong and Ulsan area), South Korea. Nickel, chromium and cobalt concentration in M. sinensis growing on serpentine soils were 87-510ppm, 81-745ppm and 3.8-44ppm, respectively. In the M. sinensis, nickel concentration was correlation with cobalt, chromium, zinc and iron concentration, respectively, cobalt concentration was correlation with chromium, zinc and iron concentration, respectively, whereas chromium concentration was positive relationship with iron. Nickel-iron, nickel-cobalt and cobalt-iron concentration of M. sinensis srowing on serpentine soils showed high significant relationship, the correlation coefficent was higher in above-ground part than root. Most of the heavy metal concentration of M. sinensis were lower than those of soils at most of the sample localities. The heavy metal concentration of M. sinensis had no relationship with those of top soils except molybdenium.
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종설논문 : 의사-제약산업체 상호작용에서의 이해상충 관리
강명신 ( Myoung Sheen Kang ),고윤석 ( Youn Suck Koh ) 한국의료윤리학회 2011 한국의료윤리학회지 Vol.14 No.3
Physician-pharmaceutical industry interaction (PPII) is ubiquitous in medical research, education, and clinical care. Conflicts of interest, which occur in the interaction, are to be properly managed at the level of the health care institution as well as at the level of individual health care personnel. The purpose of that management is to control conflicts of interest to the maximum extent possible, thereby preserving the value of public trust. Public trust is founded on the principle of prioritizing patients` interests. Founding principles of COI management are based on public trust, professional integrity, and publicity. With these founding principles the relevant stakeholders (the pharmaceutical industry, physicians, medical care institutions, and the general public) should make continuous efforts to manage COI appropriately. Above all, the awareness of influences is essential among those stakeholders. This article argues that medical professionals should appreciate and protect the value of professional integrity and that medical organizations and institutions should establish reasonable policies of COI management, including the constitution of COICs (conflicts of interest committees) and education programs. Furthermore, it is claimed that society as a whole shares the responsibility of providing an appropriate health care environment by compensating heath care providers with adequate payment in order to avoid inappropriate PPII development. Without providing reasonable health care reimbursement, legal restrictions designed to control inappropriate PPII maAy not achieve their goal.
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경피경간적 담도내시경법에 의한 폐쇄성 담도질환의 진단 및 치료
김명원,박홍배,여향순,추진호,조형철,조장현,김원석,오기창,강명원,임연근 대한소화기내시경학회 1998 Clinical Endoscopy Vol.18 No.1
Background/Aims: Obstructive jaundice is developed from the cholangiocarcinoma, biiliary tract stone, biliary benign stricture and pancreatic head cancer and is rapidly progress to cholangitis or sepsis. So early decompression, accurate diagnosis and treatment are very important. Percutaneous transhepatic choledocoscopy(PTCS) and endoscopic retrograde choledocoscopy(ERCS) have been used for evaluation of the obstructive jaundice. We performed, through the PTCS, electrohydraulic lithotripsy(EHL) for biliary tract stone rernoval, biopsy for diagnosis of biliary stric and self expandible metalic coil stent(EndocoilTM stent, Instent Co.) insertion on biliary stricture to evaluate the usefullness of PTCS in patients with obstructive jaundice. Methods: Between Auguest 1994 and September 1995, PTCS was performed in 37 patients with obstructive jaundice. First, percutaneous transhepatic biliary drainage(PTBD) with 7Fr. drainage tube was done. Three days later, we exchainged the 7Fr. drainage tube with 16Fr.. Seven days later, through the PTCS, we performed EHL, biopsy and EndocoilTM stent insertion. Results: 1) Stones were removed completely and patients were imprcaved clinically after PTCS with EHL in 17 patients with biliary tract stone. During one year, anyone of these patients were not recurred. 2) Biopsy was done in 13 patients with biliary stricture and then 7 patients were confirmed as CBD cancer. 3) EndocoilTM insertion was performed in 22 patients with biliary stricture. In one patient, EndocoilTM iltsertion was failed due to too lowerly inserted. During one year, only 4 patients developed biliary tract obstruction. Conclusion: These resuts suggest that, through the PTCS, EHL of biliary tract stones, biopsy and EndocoilTM stent insertion on biliary stricture are very useful method for biliary tract decompressiom, accurate diagnosis and treatment of patients with obstructive jaundice.
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