스트레스와 면역반응에 대한 국내 논문분석

채영란,김금순,최명애,안경애,김명애,서순림,홍해숙,정재심,박금화,이성희 대한기초간호자연과학회 2002 Journal of korean biological nursing science Vol.4 No.2

This study was aimed to analyze the variables measuring stress and imnnune responses, to identify the relationship between stress and imnnune responses, and to find out the effect of nursing interventions associated with stress and immune responses by reviewing thirty-four published articles since 1970 in Korea. The articles were selected in the field of nursing, stress management, and masters or doctoral dissertations and limited to human subject. Among these, the thirty-one articles were published since 1996 and mainly distributed in nursing(44.1%) and medicine(44.1%). The prevailing research design was nonequivalent control pre-post experimental design (41.1%). The research subjects were 55.9% for patients and 44.1% for healthy general persons including 20.6% of university students. To evaluate stress, both physiologic and psychosocial measures were adapted together in 35.3% of the articles. The most frequent two variables measuring stress and immune response were cortisol leve1(15.9%) and number or activity of natural killer ce11(25.9%). The relation between stress and immune responses was positive in 4 articles, negative in 9 cases, and none in 12 cases. Decreased stress and enhanced immune function have been found when massage, abdominal breathing, exercise, relaxation, and touch were provided as nursing interventions. The articles to investigate the relationship between stress and immune function were limited and the tested variables were diverse. Also there was no consistent evidence to correlate the stress and immune function at present. Further studies are needed to construct a valid research design and to investigate the relationship between stress and immune responses. Nursing interventions to decrease stress should be developed to result in the increased immune function and the effect of these interventions would be verified.

과민성 장 증후군의 증상 경감을 위한 비약물적 접근 고찰

최명애,김금순,안경주,채영란,최정안,홍해숙,박미정,이경숙,신기수,정재심 대한기초간호자연과학회 2005 Journal of korean biological nursing science Vol.7 No.2

There have been many trials of clinical efficacy of multicomponent and single component treatments for irritable bowel syndrome(IBS). We reviewed effects of non phamacological treatments in the IBS. Though the efficacy of multi-component approaches was unclear, several results suggest that cognitive behavioral therapy was effective in improving gastrointestinal symptoms of IBS. As a single component, cognitive therapy and relaxation with or without biofeedback could improve the symptoms and psychological health of IBS patients. Yoga, meditation, self-help information and hypnotherapy could be applicable to IBS.

옥수수 뿌리에서 전처리 방법에 따른 굴중성 반응

趙椧濟,金舜泳 대구산업정보대학 2001 논문집 Vol.15 No.-

This research was focused to develop the methods for the study of gravitropic response. The filter paper method which was wrapped the whole roots showed the similar response to the control. According to the methods, we examined the effect of 10^(-6) M IAA. The treatment of IAA inhibited the gravitropic response in all the type of pretreatment. Specially, the filter paper method showed the significant effect in the primary roots of maize.

高等學校 家政科 敎師와 學生의 家政科 敎科內容에 對한 認識 및 活容 : Centering on the Unit of Cooking Practice 調理實習單元을 中心으로

朱明子,任良淳 한국 가정과 교육 학회 1991 한국가정과교육학회지 Vol.3 No.-

The purpose of this study is to find out problems through ollking into the actual condition of management and the extent of application in cooking practice in High School Home Economics Education, and as a practical subject, to present some basic materials to contribute to accomplishing the object of High School Home Economics Education through trying to find a direction to enhance educational value. The contents of this study are these : to study with a theoretical background character, object, and contents of Home Economics referring to related books nad to investigate the actual condition of management, the extent of application to life of cooking practice unit, and standard of recognition of students and teachers about this subject and to find out rational nad efficient method of management. 552girl students and 72 home economics teachers in cities and counties in Kangwon-do were asked to answer the answer-wheet prepared. The result of this study is summerized as follows. 1.Most of the respondents regard the characters and objects of Home Economics as a metter of baisc education, education for life, and education for the wholeman, but they they neglect the aspect of education for a course of this subject. 2.Among the contents of Home Economics, students are much interested in the Unit of preparing table, especially in cooking. Most of the teachers teach the cooking unit only explanation without practice because of the lack of material and human resources. 3.Students have desire to do cooking practice, but the extent of application to their real life appears to be low. 4.It appears to be necessary that boy students as well as girl students should learn Home Economics as an education for preparation for managing housework. 5.Home Economics teachers are mostly satisfied which their teaching profession. But teachers who have been teaching for 3 or 5 years appear not to be satisfied with it. 6.Although Home Economics teachers can teach Cooking practice Unit with confidence, they usually do it theory rater than with practice, and they evaluate it after practicing, but most of them do not add the result to the student's grade. 7.They use most of the cookers fixed on the standard list of High School Cooking Practice appliances, but they seldom use electric heating cookers. According to the above result, we should take the following into account in order to improve probiems shown below. 1) Contents of this subject should consist of definite ones so that students can find out their aptitude and ability. 2) Video materials for efficiency of cooking practice, guide books for cooking experiment, and tools for evaluation should be developed and distributed. 3) Boy students as well as girl students should learn Home Economics together. 4) The extent of application should be enhanced by developing concrete programs of Home Profect, grade repectively so that, in addition to the scientific knowledge and function, education for how to see things and how to think should be emphasized. 6) It is required that contents should consist of meterials for settling and developing traditonal food culture. 7) Environment problems and welfare affairs of aged society as well as international affairs of the world food situation, and development and exploitation of new food resources should be dealt coherently in vocation and home economics education subjects of elementary, middle, and high school. 8) Each Home Economics teacher is required to spare time for his self-study on good condition, to be very good at contents of all spheres of practics in Home Economics, and to have confidence in teaching the subject. 9) The number of students in practice lesson should be limited to 20 to 30 in order to meet the need of the students. 10) A plan for establishing organization of school cooking practice should be discussed by regional groups. 11) A new design of cooking practice room which is available throughout the year should be made. 12) A study association of vocation and home economics should be established to provide teachers with information and opportunity of re-education, and to make and distribute teaching materials so that teachers may have leading abilities coping with internationalization and informationalization with up-to-date attitude. 13) Practical aspect of Home Economics should be emphasized, with which students are able to choose life-information and to play a chould consumer's role.

중 ·고등학교 여학생의 식생활관리 능력에 관한 실태 연구

주명자,임양순 한국 가정과 교육 학회 1993 한국가정과교육학회지 Vol.5 No.-

The ability of the meal management of the middle and high school girls in Kangweon area was surveyed by Likert scale questionnaire. The results were as follows: 1. The ability of the meal management of the middle school girls have good marks in table etiquette as 3.93 point, in using cooking apparatus as 3.86 points, in sanitation management as 3.76 points and in food selection as 3.70 points, but not so good in food preparation as 3.56points, in meal planning as 3.22 points and in table setting as 3.20 points. 2. For the high school girls they have good marks in table etiquette(3.99 points), using cooking apparatus(3.96 points), food selection(3.95 points) and sanitation management(3.93 points), but not so good in food preparation(3.64 points), meal planning and table setting(3.36 points each). 3. And we found that they have a significant difference in ability of meal planning, table setting, food selection and sanitation manabement(P<0.001) but no significant difference in food preparation, using cooking apparatus and table etiquette between middle and high school girls. In general they have a significant difference in ability of meal management between middle and high school girls.

1,5-Diphenylhydantoins을 위한 새로운 Methyl α-Anilinophenylacetate 유도체의 합성

권순경,최희전,박명숙 德成女子大學校 藥學硏究所 2001 藥學論文誌 Vol.12 No.1

For the development of new COX-2 inhibitor, novel key intermediates (2∼4) synthesized through esterification, bromination and α-substitution from phenylacetic acid. The methyl phenylacetate 2 was synthesized through reflux phenylacetic acid with sulfuric and methanol. The methyl α-bromophenylacetate 3 was produced through radical bromination using N-bromosuccinimide from 2. The optical amination to introduce anilino group was contolled under 80℃ in DME. The bromo intermediate was converted to the final methyl α-anilinophenylacetate 4 through reaction with aniline.

흰쥐 뇌줄기에서 광주기 및 melatonin주입이 serotonin면역반응에 미치는 영향

김명순,전승원,이창현 대한해부학회 2003 Anatomy & Cell Biology Vol.36 No.6

GABA agonist와 antagonist의 주입이 닭의 monocular Optokinetic nystagmus(OKN)에 미치는 영향

김명순 우석대학교 생명과학연구소 1998 생명과학연구소 논문집 Vol.2 No.-

Chicken monocular head and eye optokinetic nytagmus(OKN) were observed by coil recording after intravitreal administration of GABA agonist(THIP) and antagonist (SR95531) into the open and closed eye. Before injection of drugs the chicken displayed an OKN for T-N stimulation being more efficient in evoking this visuomotor reflex than N-T stimulation. The injection of GABA agonist(THIP) into either the open or closed eye induced a decrease of the head and eye OKN. On the other hand, the injection of GABA antagonist(SR 95531) into the closed eye, the head and eye OKN evoked an increase whereas the injection of GABA antagonist(SR 95531) into the open eye, the head and eye OKN provoked a decrease or disappearance. Thus, GABA antagonist abolished the directional asymmetry of the head and eye OKN, indicating the involvement of GABAergic mechanisms in the inhibition of the N-T component of the monocular OKN.

통합적 림프부종 간호중재 개발 연구

조명옥,정향미,전점이,손수경,우영자,노미영,박순옥 성인간호학회 2003 성인간호학회지 Vol.15 No.2

The purpose of this study was the development of a comprehensive nursing intervention program for the client with acute lymph stasis and stage I lymphedema. Method: The Quasi-experimental design using a non-equivalent control group was used. The subjects were 22 stroke patients with lymph stasis in the control group and 23 patients in the experimental group. The complex physical therapy of Casley-Smith was carried out to the control group for 0 hours, and comprehensive nursing intervention for the experimental group was carried out for 60 minutes. The data for this study was gathered from Feb. 2002 until June 2002 and pertains knowledge about lymphedema, self-care for managing lymphedema, and circumferences of affected limbs. Data was analyzed by mean, standard deviation, x^2-test. And t-test. Result: The changes in knowledge about lymphedema, self-care practices, and circumference of affected limbs after nursing intervention did not show significant differences between control group and experiment group. Conclusion : It can be concluded that comprehensive nursing intervention had more efficiency than complex physical therapy in the treatment of edema for stroke patients because of it’s simplicity and time saving. Thereby, the comprehensive nursing intervention program developed in this study would be a useful therapy for the clients with lymph stasis and early stage lymphedema.

Cyclooxygenase-2 저해제로서의 benzothiazine 유도체 합성과 항염작용 평가

신혜순,박명숙,권순경 德成女子大學校 藥學硏究所 2000 藥學論文誌 Vol.11 No.1

The antiinflammatory mechanism of NSAIDs is attributed to the reduction of prostaglandin synthesis by the direct inhibition of cyclooxygenase. Inhibition of prostaglandin production in organs such as stomach and kidney can result in gastric lesions, nephrotoxicity and increased bleeding. In this study, newly designed COX-2 inhibitors, synthesized 1,2-benzothiazine derivatives, were screened in vitro for selectivity of COX-1 and COX-2 inhibition properties. Lead compounds in the structure-activity relationship were studied to synthesize new highly selective COX-2 inhibitors. To determine inhibitory effect of COX-2, synthesized 1,2-benzothiazine derivatives were screened with accumulation of prostaglandin by lipopolysaccharide (LPS) in aspirin-treated macrophages and murine macropharge cell. Some of synthesized 1,2-benzothiazine derivatives were shown to be effective as selective COX-2 inhibitory activity. Others exhibited a preferential inhibition of COX-2, although some COX-1 inhibitory activity was still present. As a conclusion, simple monomer derivatives were more active than dimer derivatives. Substitution of halogen (Br, Cl) on the benzothiazine nucleus slightly enhanced inhibition activity.