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      • KCI등재

        Inelastic Analysis and Damage Assessment of Hydraulic Arched Tunnels in Different Near-Fault Regions

        Benbo Sun,Mingjiang Deng,Sherong Zhang,Chao Wang,Wei Cui,Xiaohua Zhao,Lei Kou,Binghan Xue 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.9

        The seismic natural hazard event is a threat of unpredictable events, which can easily cause incalculable damage to hydraulic tunnels. Traditionally, it is necessary to introduce as-recorded ground motions (GMs) appropriately for hydraulic arched tunnels during seismic design to avoid the unfavorable situation of large-scale collapse. However, the lack of adequate current selected methodology considering the accurate engineering site relative to the fault line in this type can result in more considerable deformations and severe damage to structures. Actually, the detailed explanation of the seismic design code of hydraulic tunnels cannot support the specific consideration of the spatial region effects since the considerable uncertainty of engineering sites in water resources and hydropower engineering. To address this issue, the present study proposes a novel selected methodology of as-recorded GMs that integrates the geographic location distribution of the strong earthquake monitoring station instead of the actual engineering site relative to the fault line. Subsequently, three-dimensional finite element models of a hydraulic arched tunnel reveal the possible seismic behavior of the tunnel induced by as-recorded GMs in different near-fault regions. Furthermore, the optimal IM between different near-fault regions and structural responses is also discussed through correlation analysis because it can describe the seismological features of as-recorded GMs, which has a crucial role in seismic design and performance assessment. The results reveal that the as-recorded GMs in the hanging wall region can induce more significant deformations and severe damage to the structure than other near-fault regions of as-recorded GMs. Meanwhile, the seismological characteristics and selected optimal IM for as-recorded GMs in different near-fault regions significantly differ. In summary, data and observations from these results highlight that considering the near-fault region effect is critical in optimizing the seismic design code.

      • KCI등재

        Study on optimal conditions and adsorption kinetics of copper from water by collodion membrane cross-linked poly-γ-glutamic acid

        Xiangting Wu,Aiyin Wang,Xiaojie Zheng,Guoxing Li,Xinjiao Dong,Mingjiang Wu 한국화학공학회 2013 Korean Journal of Chemical Engineering Vol.30 No.6

        Poly-γ-glutamic acid (γ-PGA) is a novel polyamino acid formed through microorganism fermentation and biosynthesis. In the present test, membrane (PGA-C) formation by γ-PGA and collodion was performed by using 0.1%glutaraldehyde as a cross-linking agent. A study was conducted on the PGA-C adsorption of Cu2+, specifically the related adsorption equilibrium and kinetics, desorption and regeneration. The results show that with an initial solution pH=5.5and at 318 K, the static adsorption isotherm behavior of PGA-C is in compliance with the Langmuir model and is beneficial to the adsorption of the metal. Meanwhile, with the reaction lasting for 30min, adsorption equilibrium was reached with a maximum adsorption capacity up to 7.431 mg/g. The entire reaction process follows the pseudo-second-order kinetics. By using PGA-C, good regeneration results were obtained after adsorption-generation-adsorption cycling with an HCl solution (0.1 mol/L) as regeneration liquid.

      • An Improved Tone Model for SVM Based Tone Recognition

        Qian Liu,Jinxiang Wang,Mingjiang Wang 보안공학연구지원센터 2016 International Journal of Hybrid Information Techno Vol.9 No.10

        Tonal information is important for Chinese Mandarin speech recognition and understanding. Tone information is carried on the shape of fundamental frequencies. When constructing a tone recognition system based on support vector machine, the fundamental frequencies should be normalized by curve fitting method. The fitting coefficients are input data of support vector machine, but it cannot precisely represent the shape of fundamental frequencies. An improved tone model is proposed, which added some other information of fundamental frequencies, such as the maximum and minimum value, the position of maximum and minimum values, the fundamental frequency values of first and last point. The experimental result shows that the proposed model is more accurate with the shape of fundamental frequencies and the accuracy rate of tone recognition is increased by using the improved tone model.

      • KCI등재

        Injectable Hydrogels with Near-Infrared Controlled Drug Delivery for In Situ Photothermal/Endocrine Synergistic Endometriosis Therapy

        Wei Tian,Chenyu Wang,Ran Chu,Haiyan Ge,Xiao Sun,Mingjiang Li 한국생체재료학회 2023 생체재료학회지 Vol.27 No.00

        Background Endometriosis is a common gynecological disease in women of childbearing age. Commonly used treatment methods, such as endocrine and surgical therapies, display poor therapeutic effects with a high relapse probability. Thus, novel treatments for endometriosis are required. Methods In our study, polydopamine (PDA), letrozole (LTZ), and agarose (AG) hydrogels were combined to construct an injectable hydrogel with near-infrared controlled drug delivery named LTZ-PDA@AG hydrogel for endometriosis treatment. The release of letrozole can be accurately controlled by the near-infrared light intensity, exposure duration, polydopamine concentration, and hydrogel composition. Meanwhile, we isolated endometrial stromal cells from endometrium in patients with endometriosis, and constructed the rats’ model of endometriosis to verify the biological effects of LTZ-PDA@AG hydrogel. Results Owing to the sufficiently deep penetration of near-infrared light, the LTZ-PDA@AG hydrogel displayed a high temperature increase for efficient photothermal therapy. In addition, high local temperatures can further enhance the diffusion and penetration of letrozole, thereby achieving excellent therapeutic effect in vivo. Importantly, the in vivo and vitro test demonstrated the capacity of the nanocomposite hydrogel for endocrine-photothermal synergistic therapy and the biocompatibility. Conclusion Our work proposes a novel concept for precision endometriosis therapy by photothermal-enhanced endocrine therapy for endometriosis, which is proposed for the first time for the treatment of endometriosis and demonstrates excellent potential for further clinical translation.

      • A Feature Parameter Modification Algorithm for Voice Activity Detection Based on Support Vector Machine

        Qian Liu,Jinxiang Wang,Mingjiang Wang 보안공학연구지원센터 2015 International Journal of Grid and Distributed Comp Vol.8 No.6

        A feature parameter modification algorithm is proposed to increase the accuracy of voice activity detection that based on support vector machine and energy acceleration parameters. The three energy acceleration parameters should have the equal importance for voice activity detection, in that all the three parameters can suitably characterize the classification features of speech and non-speech frames. For the three energy acceleration parameters, its minimum values vary a little; but its maximum values are greatly different. When radial basis function is chosen as the kernel function for voice activity detection, the coordinate values in Hilbert space is dominative determined by the energy values over a sub-region spectrum, the other two parameters only have a few contributions to it. The proposed algorithm extends the three energy acceleration parameters into the nearby or same order of magnitude. It make the three energy acceleration parameters at the same importance level in the calculation of coordinate values in Hilbert space, and can finally increase the accuracy of voice activity detection. The experimental results show that this algorithm can increase the accuracy of voice activity detection in the absence of noise and noise conditions.

      • SCISCIESCOPUS

        Antitumor bioactivity of porphyran extracted from <i>Pyropia yezoensis</i> Chonsoo2 on human cancer cell lines

        He, Dan,Wu, Siya,Yan, Liping,Zuo, Jihui,Cheng, Yang,Wang, Hanfei,Liu, Jian,Zhang, Xu,Wu, Mingjiang,Choi, Jong‐,il,Tong, Haibin John WileySons, Ltd 2019 Journal of the Science of Food and Agriculture Vol.99 No.15

        <P><B>Abstract</B></P><P><B>BACKGROUND</B></P><P><I>Pyropia yezoensis</I>, rich in porphyran, is a medicine‐edible red alga. In the present study, the physicochemical characteristics, conformational states and antitumor activities of a novel porphyran extracted from the high‐yield algal strain <I>Pyropia yezoensis</I> Chonsoo2 and its two degraded derivatives by gamma irradiation were investigated.</P><P><B>RESULTS</B></P><P><I>Pyropia yezoensis</I> porphyran is a water‐soluble, triple‐helical sulfated hetero‐galactopyranose, named PYP. PYP was degraded by gamma irradiation at 20 kGy and 50 kGy, giving two low molecular weight derivatives comprising PYP‐20 and PYP‐50, respectively. PYP with a higher molecular weight has a solution conformation different from PYP‐20 and PYP‐50. Three porphyrans had no toxicity in normal human liver cells (HL‐7702) and showed antitumor effects on Hep3B, HeLa and MDA‐MB‐231. They had better antitumor against HeLa cells, exhibiting a similar inhibition ratio compared to 5‐fluorouracil, with PYP especially exhibiting a higher inhibition ratio than 5‐fluorouracil. With respect to HeLa cells, the different antitumor activities might be related to porphyran molecular weight and solution conformation. Furthermore, the HeLa cell cycle was blocked in the G2/M phase after PYP treatment, leading to cell proliferation inhibition. The induction of cell cycle arrest was related to the changes in the expression of p21, p53, Cyclin B1 and cyclin‐dependent kinase 1.</P><P><B>CONCLUSION</B></P><P><I>Pyropia yezoensis</I> porphyran, as applied to medicine and functional food, could potentially be used as a non‐toxic natural adjuvant in cancer therapy. © 2019 Society of Chemical Industry</P>

      • Improved DV-Hop Localization Algorithm Based on Anchor Weight and Distance Compensation in Wireless Sensor Network

        Ming Jiang,Yunfei Li,Yuan Ge,Wengeng Gao,Ke Lou,Shinong Wang,Juanjuan Jiang 보안공학연구지원센터 2016 International Journal of Signal Processing, Image Vol.9 No.12

        Position information is the foundation of massive applications in Wireless Sensor Network(WSN). Three improved positioning algorithms based on DV-Hop are proposed in order to enhance the positioning accuracy of wireless sensor nodes. First improved algorithm is distance compensation algorithm (DCA) that creates a triangle model to compensate the estimated distance. The second improved algorithm creates a new chain table for all anchor nodes to record and compute the average hop distance. The third improved algorithm is weighting different anchor nodes with anchor nodes’ nearest unknown nodes. The second and third improved algorithms are based on the DCA. The simulation results show that the three improved algorithms are better than the original DV-Hop in localization accuracy. Compared to the original DV-Hop algorithm, the simulation results shows that the three improved algorithms proposed in the paper increase the positioning accuracy of the unknown nodes.

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