초기 자궁내막암 환자에서의 복강경유도하 질식 자궁절제술과 복식 자궁절제술에 대한 비교 연구

김민규 ( Min Kyu Kim ),최동석 ( Dong Seok Choi ),김우영 ( Woo Young Kim ),최철훈 ( Chel Hun Choi ),김태중 ( Tae Joong Kim ),이정원 ( Jeong Won Lee ),김병기 ( Byoung Gie Kim ),이제호 ( Je Ho Lee ),배덕수 ( Duk Soo Bae ) 대한산부인과학회 2006 Obstetrics & Gynecology Science Vol.49 No.12

목적: 초기 자궁내막암의 수술적치료 시 복강경유도하 질식 자궁절제술 및 골반림프절절제술군과 복식수술군의 수술결과 및 재발율에 대해 비교하고자하였다. 연구 방법: 2003년 3월부터 2005년 5월까지 초기 자궁내막암 환자를 인구학적 특성이 같은 63명을 선택하여 복강경유도하 질식 자궁절제술 및 골반림프절절제술군 26명, 복식수술군 37명으로 나누어 수술 전후 혈색소 차이, 평균수술시간, 취득한 골반림프절갯수, 평균재원일수, 추가치료율, 재발률을 비교하였다. 결과: 복강경유도하 질식 자궁절제술 및 골반림프절절제술을 시행한 군과 복식수술을 시행한 군과의 비교에서 수술 전후 혈색소 차이, 평균수술시간, 취득한 골반림프절 갯수, 평균재원일수, 재발률에 통계적으로 유의한 차이가 없었다. 결론: 초기 자궁내막암의 수술 시 복강경유도하 질식자궁절제술 및 골반림프절절제술 방법이 복식방법에 비해 수술결과 및 재발률에 통계적으로 유의한 차이가 없으며 그 대체 수술법으로 많은 활용이 기대되었다. Objective: To compare laparoscopic surgery with conventional abdominal surgery in patients with early stage endometrial cancer. Methods: A retrospective review of 63 patients with early stage endometrial cancer managed between March 2003 and May 2005. Two groups were defined whether they had been treated by laparoscopy (case group: n=26) or by laparotomy (control group: n=37). We compared age, body mass index (BMI), hemoglobin change, operation time, number of pelvic lymph nodes, hospital stay, case with adjuvant treatment and recurrence between two groups. Results: There was no statistical difference in characteristics (age, BMI, nulliparity, previous abdominal surgery, FIGO stage, histologic grade). between case and control group. In addition, there was no statistical difference in operation data and outcomes between two groups. Hemoglobin changes were 1.1 g/dL (case group) vs 1.7 g/dL (control group) (p=0.072). Operation time was 131 min vs. 115 min. The numbers of lymph nodes obtained were 8.7 vs 7.7 (right) 9.2 vs. 7.6 (left). Hospital stays were 8.4 vs. 9.2 days. Adjuvant treatment cases were 7 vs. 15. Recurrent case was one in each group. Two patients initially evaluated by laparoscopy were converted to laparotomy due to bleeding and adhesion. Conclusion: Laparoscopic surgery for treatment of early endometrial cancer is a safe and effective alternative to laparotomy . However, long-term survival and risk of recurrence have yet to be determined.

Ether-free polymeric anion exchange materials with extremely low vanadium ion permeability and outstanding cell performance for vanadium redox flow battery (VRFB) application

Cha, Min Suc,Jo, Sang Woo,Han, Seung Hui,Hong, Soo Hyun,So, Soonyong,Kim, Tae-Ho,Oh, Seong-Geun,Hong, Young Taik,Lee, Jang Yong Elsevier 2019 Journal of Power Sources Vol.413 No.-

<P><B>Abstract</B></P> <P>Ether-free poly(<I>p</I>-phenylene)-based anion exchange membrane materials with outstanding vanadium ion blocking properties are reported. The synthesized ionomers with a rigid backbone structure show small dimensional variations despite the high ion exchange capacities. Among the synthesized membranes, the QPPP-2 membrane with ion exchange capacity of 2.1 meq·g<SUP>−1</SUP> exhibits high anion (OH<SUP>−</SUP>, SO<SUB>4</SUB> <SUP>2−</SUP>, and Cl<SUP>−</SUP>) conductivity. The QPPP-2 membrane shows an extremely low diffusion coefficient (2.12 × 10<SUP>−9</SUP> cm<SUP>2</SUP> min<SUP>−1</SUP>) for VO<SUP>2+</SUP>, which is much lower than that of Nafion 115 (2.88 × 10<SUP>−6</SUP> cm<SUP>2</SUP> min<SUP>−1</SUP>), indicating the vanadium ion blocking property of QPPP-2. Moreover, the chemical and operational stabilities of the membranes are investigated <I>via</I> ex situ soaking tests in 0.1 M VO<SUB>2</SUB> <SUP>+</SUP> solution and in situ operation tests for 100 cycles, respectively. The vanadium redox flow battery single cell assembled with the QPPP-2 membrane exhibits a coulombic efficiency of 99%, voltage efficiency of 87%, and energy efficiency of 86% during 100 cycles at 80 mA cm<SUP>−2</SUP>. The excellent chemical, morphological, and electrochemical properties of the QPPP-2 membrane make it suitable for use in vanadium redox flow battery.</P> <P><B>Highlights</B></P> <P> <UL> <LI> AEMs are fabricated by a Ni(0)-catalyzed cross-coupling reaction. </LI> <LI> The synthesized ionomers indicated excellent dimensional and chemical stability. </LI> <LI> Ether-free polymeric AEMs showed extremely low vanadium ion cross over. </LI> <LI> The performance of developed AEM showed high EE (87%) with high capacity retention. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

총경동맥 폐쇄시간에 따르는 국소 뇌혈류 변화 : 실험적 연구 An Experimental Cat Model

강준기,성태경,조병일,백민우,김문찬,허춘웅,하영수,송진언 대한신경외과학회 1983 Journal of Korean neurosurgical society Vol.12 No.3

The microvasculature of the brain is also quite susceptible to ischemic insult, and substantial portions of the brain are not reperfused after restoration of the blood supply following overtime of critical ischemic periods. The purpose of this series of experiments was to determine the effects of ischemia on subsequential regional cerebral blood flow measurements and cortical electric activities following reperfusion after ischemia and also to define the proper time of vascular occlusion without irreversible neural damage. Cerebral ischemia was induced in cat by bilateral common carotid occlusions for periods of 10, 30, to 60 minutes, and the blood supply was reperfused for 3 hours after clamp-off. Regional cerebral blood flow(rCBF) was measured by hydrogen clearance technique following ischemia, restoration of blood supply and electroencephalogram recovery could be predicted according to the rCBF. Forty adult cats weighing 2.7 to 4.0㎏ were used in this study. The animals were divided into 4 groups of 10 cats each : normal control, 10 min-clamped, 30 min-clamped, and 60 min-clamped groups. The results obtained were as follows : 1) The mean rCBF was 24.6±7.0㎖/100g/min in control group. 2) Bilateral carotid occlusions resulted in a reduction of the rCBF(12.4±4.1㎖/100g/min) to 50% of control flow on both hemispheres. 3) Sequential changes of the rCBF after reperfusion : (1) There was restored the rCBF(21.3±5.1㎖/100g/min) to control flow in the 10 minutes-clamped group. (2) There was a 85% recovery of control flow in the 30 minutes-clamped group. (3) There was a only 25% recovery of control flow in the 60 minutes-clamped group. 4) A close correlation was found between cortical electrical activity and rCBF suggesting a threshold relationship. (1) The changes of cortical electric activity began to notice at rCBF less than 17.4±4.7㎖/100g/min. (2) The recovery of cortical electric activity noted at rCBF more than 10.2±2.3㎖/100g/min. 5) There was no evidence of ischemic involvement at the cortex, white matter and basal ganglia in the 10 minutes clamped group, but demonstrated a dense wedge shaped infarct at the cortex and uncus herniation in the 60 minutes clamped group. The rCBF and cortical electric activity restored to normal values in reperfusion within 10 minutes after occlusion of both common carotid arteries.

유화처리 바이오디젤이 도포된 콘크리트의 침투깊이 판정

백철 ( Baek Cheol ),김태우 ( Kim Tae-woo ),이재진 ( Lee Jae-jin ),이동윤 ( Lee Dong-yun ),한민철 ( Han Min-cheol ),한천구 ( Han Cheon-goo ) 한국건축시공학회 2017 한국건축시공학회 학술발표대회 논문집 Vol.17 No.2

This study is to provide a evaluation method for the penetration depth of emulsified refined bio diesel(ERBD)applied to a surface of the concrete by using water absorption capability of the concrete. The concrete applied with ERBD was immersed at water for 1 min., 5min., and 10 min. and then was checked the brightness with elapse of time. Test results indicated that there was clear difference between ERBD part and non ERBD part in concrete specimen after measuring the brightness until 120min.

조기 발병 양극성 장애 환자의 임상적 특징 : 후향적 의무기록 조사 연구

우영섭,박민현,서호준,채정호,전태연,박원명 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.5

Objective : Bipolar disorder is a disease with diverse clinical profiles and outcomes. In recent years, it is suggested that if bipolar disorder occurs early in one's life, functional and symptomatic prognoses are poor. The prognoses include severe Symp-toms, frequent psychotic symptoms, comorbidity ofmental illnesses, slow improvement of the symptoms, and high suicide rate. We investigated the clinical characteristics of early onset bipolar inpatients. Method : The subjects of this study were selected from the patients who were discharged after hospitalization between January 1, 2001 and May 31, 2005 and diagnosed with bipolar disorder according to DSM-IV criteria. These patients were examined for the following data ; the type of bipolar disorder, comorbid psychiatric disorders, the age at onset of the illness, the acuteness of the disorder, and the duration of the disorder. The presence of four major clinical psychopathology, rapid cycling, Psychotic symptoms, comorbid psychiatric disorders, and suicide attempt, was also examined. The patients whose onset of the illness was before the age of 19 were classified as the early onset group and after the age of 19 were classified as the late onset group. Data on demographics, family histories, four major clinical psychopathologies and other clinical variables were compared between the early onset group and the late onset group. Results : Of the 53 patients, 19 patients belonged to the early onset group. There was higher incidence ofpsychotic Symp-toms in the early onset group than in the late onset group, and the difference was statistically significant according to the χ² - test (84.2% vs 44.1%, P=0.005). The incidence of comorbid psychiatric disorders was higher in the early onset group than in the late onset group, and the difference was also statistically significant according to the χ²-test (52.6% vs 23.5%, P=0.032).However, there was no statistically significant difFerence between the groups regarding the incidence of rapid cycling and suicide attempt. The result of logistics regression showed correlation of psychotic symptoms (0R=6.756 ; 1.655≤95% CI≤27.580) and comorbid psychiatric disorders (0R=3.611 ; 1.088≤95% CI≤11.984) with the early onset group. Conclusion : Early onset of bipolar disorder is related to the manifestation of psychotic symptoms and frequently accom-panies comorbid psychiatric disorders. The results of this study will help understand the mechanism of the onset of complexbipolar disorder and estimate the prognosis.

아세트산의 탈수반응을 위한 MCM-41의 표면개질 및 적외선 분광법을 이용한 표면특성 분석

우창수,박민태,이병민,이호인 한국공업화학회 2003 응용화학 Vol.7 No.2

Catalytic dehydration of acetic acid was performed over surface-modified MCM-41. Calcination of silylated MCM-41 under air regenerated successfully silanol groups as the active sites for dehydration of acetic acid. In-situ FTIR spectroscopy using pyridine as a probe molecule revealed that as the pretreatment temperature before silylation increased, the concentration of Lewis-acidic sites was enhanced. The enhanced concentration of Lewis-acidic sites augmented the bridged adsorption species of acetic acid on the surface of the modified catalyst, which significantly promoted the catalytic activity.

지하철 기관사의 운행 중 사고경험에 따른 정신건강의 차이

우종민,강태영,이정은 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.1

목적: 본 연구는 지하철 운행 중 사고경험이 있는 기관사의 PTSD와 공항 장애 유소견자의 분포를 알아보고자 하였다. 또한 운행 중 사고경험이 있는 기관사와 사고경험이 없는 기관사와의 공황 장애의 차이를 알아보고, 더불어 스트레스 수준과 업무 관련 증상 및 수면 건강의 차이를 알아보고자 실시되었다. 방법: 2004년 4월∼5월 수도권 지하철 기관사 628명을 대상으로 스트레스 증상 수준, 수면 건강, 공황 장애, 임상가를 위한 PTSD 설문지 등을 이용하여 정신건강 상태를 조사하였다. 결과: 운행 중 사고경험이 있는 기관사의 PTSD 유소견자 비율이 일반인구에 나타나는 PTSD 유병률에 비해서 높았으며, 공황 장애와 공병도 높은 것으로 나타났다. 또한 사고경험이 있는 기관사는 없는 기관사에 비해서 공황 장애 유소견자의 비율이 높으며, 스트레스 증상과 그 하위척도인 우울 증상과 분노 증상도 높은 것으로 나타났다. 뿐만 아니라 근무 관련 증상으로는 일에 대한 의욕 저하와 집중력이 저하되어 실수가 많은 것으로 나타났다. 일부 수면 건강도 사고경험이 있는 기관사가 없는 기관사에 비해서 좋지 않은 것으로 나타났다. 결론: 운행 중 사고경험은 정신적인 건강을 위협할 뿐만 아니라 업무 효율성도 떨어뜨리게 된다. 따라서 이러한 스트레스의 악영향을 없애기 위해서 사고와 연관되어 나타나는 심리적인 반응 및 증상을 이해하고 외상후 스트레스 장애 및 공황 장애와 같은 후유증을 치료하는 프로그램을 개발하고 활용해야 한다. Objectives: This study examined the prevalence of Post traumatic stress disorder(PTSD) and the comorbidity with panic disorder in subway drivers who experienced accidents on the track. In addition, this study examined the differences in panic disorder, stress levels, work-related problems, and sleep disturbances between drivers with and without an accident-experience. Methods: 628 Seoul metropolitan subway drivers were participated in this study. We assessed mental health status of the subjects using the Clinician-administered PTSD scale (CAPS), panic disorder scale based on the DSM-IV criteria, Worker's Stress Response Inventory, and Sleep Questionnaire. Results: The prevalence of PTSD and comorbid panic disorder was significantly higher among those drivers who had experienced accidents than in those who had not. Drivers with an accident experience showed significantly higher somatic, depressive, anger symptoms in the stress measures, and more sleep problems than those drivers without an accident experience. Conclusions: The experience of an accident on the track threatens both the work efficiency and the mental health of drivers. In order to reduce the negative effect of an extremely stressful event related to accidents, intervention programs for PTSD and panic disorder need to be developed and utilized.

南北韓의 正統性 比較

閔丙徽,李瑛雨,金宇泰 경북대학교 법정대학 1978 法大論叢 Vol.16 No.-

Throughout 5,000 years of its history Korean people have endured numerous aggressions and even loss of sovereignty and survived as a race, retaining its cultural identity. 35 years of Japanese colonization between 1910 and 1945 was the most humiliating period in Korea's history, but thanks so the victory of the Allied Powers in the Pacific War Korea was liberated from the Japanese colonial rule. However, the victorious Powers-the United States and the Soviet Union-soon divided Korea unilaterally and created two separate political entities in the peninsula; the Republic of Korea in the south and the Democratic People's Republic of Korea in the north, respectively. These two regimes maintain opposing ideologies and political systems; Liberal democracy in the south and totalitarian communism in the north. Accordingly, the task facing Koreans is the achievement of the reunification of the divided peninsula in a peaceful manner. In order to accomplish that one has, first of all, to examine and evaluate political ideologies and systems of the two regimes and determine which side has inherited and is maintaining orthodoxy from the perspective of Korean history. And the one judged to be the "torch carrier" of Korean heritage must take the initiative and leadership in realizing the solemn task of the reunification of Korea. The aim of this study, thus, is to compare and evaluate two Koreas in terms of political systems and nationalism in order to confirm that it is the Republic of Korea in the south, which proves to be the "winner" on both accounts. The first chapter deals with the conceptual framework of the terms "legitimacy" and "orthodoxy" in comparing the two Koreas. In the second chapter the political systems of two Koreas are compared and analyzed on the basis of liberal democracy and totalitarian communism. The third chapter compares the legitimacy of the two Koreas from the perspective of Korean nationalism. The Repuclic of Korea in the south recognizes positive value of nationalism, asserting that the essential ingredient of nationalism stems from the people in its totality. North Korea's concept of people, by contrast, is throughly Marxist-Leninist. It claims that the nation is subordinated to the class and is a product of capitalism, thus faithfully echoeing the Marxist prediction in the "withering away" of the state system. Furthermore, north Korea negates nationalism by proclaiming its adherence to the proletariat internationalism. Despite its denial of nationalism on the basis of Marxist theory of history, however, north Korea supports nationalism as a tactical strategy in its propagnda campaign waged at home and abroad. The legitimacy of south Korea's claim to inherit the spirit of Korean nationalism is based on its belief in the people as the backbone of a nation. its opposition to totalitarianism, humanism and peace, and anti-communism. By contrast, north Korea's Marxist concept of class struggle, its belief in proletariat dictatorship, inhumane cruelty, aggressive bellicosity and other alien concepts certainly disqualify it as the rightful heir apparent to the tradition of Korean nationalism.

무흡광색소 생물의 감광수용체 개발에 관한 연구(Ⅰ) : 표고버섯 중의 광감응성 mitochondrial ATPase Light-Induced Mitochondrial ATPase in the L. edodes (Berk) Sing

민태진,조석우,박상신 동국대학교 자연과학연구소 1987 자연과학연구 논문집 Vol.7 No.-

표고버섯의 미토콘드리아는 설탕 농도 44~50% 사이에서 분리 정제 되었다. 파장 변화에 따른 미토콘드리아성 ATPase의 비활성도는 680nm 파징에서 가장 증가하였다. 680nm에서 빛 조사 시간 변화에 따른 활성도는 5분 동안 조사 하였을 때 가장 증가 하였다. 최적 광조건(680nm 5분)에서 조사한 이 효소의 최적 pH 및 최적 온도는 7.5와 59℃였다. 최적 광조건에서 얻은 이 효소는 Fe³, Fe², Mg², K 및 Ca²이온에 의하여 활성화 되었고, Na이온에 의하여 억제 되었다. Mitochondria in the L. edades was purified by linear sucrose density gradient centrifugation. The mitochondrial ATPase activity was investigated by various wavelength illumination for 30 min at dark state. The mitochondrial ATPase activity was stimulated 1.6 fold by 680nm illumination compared with dark control group. The mitochondrial ATPase activity of different light illumination time at 680nm was stimulated 2.3 fold at 5minuted compared with dark control group. Its optimum pH and temperature were found to be 7.5 and 59℃ after illumination for 5 minutes at 680nm. The mitochondrial ATPaee activity was activated by 5 mmol Fe³, 0.1mmol Mg², 0.5mmol K, and 0.1mmol Ca²ion. But the enzyme was ingibited by 5mmol Na ion.

아세트산의 탈수반응을 위한 MCM-41의 표면개질 및 적외선 분광법을 이용한 표면특성 분석

우창수,박민태,이병민,이호인 한국공업화학회 2003 응용화학 Vol.7 No.1

Catalytic dehydration of acetic acid was performed over surface-modified MCM-41.Calcination of silylated MCM-41 under air regenerated successfully silanol groups as the active sites for dehydration of acetic acid. In-situ FTIR spectroscopy using pyridine as a probe molecule revealed that as the pretreatment temperature bofore silylation increased, the concentration of Lewis-acidic sites was enhanced. The enhanced concentration of Lewis-acidic sites augmented the bridged adsorption species of acetic acid on the surface of the modified catalyst, which significantly promoted the catalytic activity.