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        비린내와 조직감이 개선된 치즈 토핑 반건조 조미 피조개(Scapharca broughtonii)의 개발 및 특성

        강상인 ( Sang In Kang ),김예진 ( Ye Jin Kim ),이지운 ( Ji Un Lee ),박지훈 ( Ji Hoon Park ),최관수 ( Kwan Su Choi ),황지영 ( Ji-young Hwang ),허민수 ( Min Soo Heu ),이정석 ( Jung Suck Lee ) 한국수산과학회 2021 한국수산과학회지 Vol.54 No.6

        Methods for the development of home meal replacement seafood tailored to consumer needs for the advanced use of Broughton’s ribbed ark Scapharca broughtonii (BRA) in Korea are required. In this study, we developed a cheesetopped, semi-dried, and seasoned Broughton’s ribbed ark (S-BRA) tailored for the younger generation with an improved texture and fish odor. The optimization of conditions to improve the texture and fish odor was performed using RSM. The design of the model was appropriate because there was no significant difference (P>0.05) between the predicted and actual values of moisture content, hardness, and overall acceptance, and the optimal preparation conditions were a vinegar content of 2.68%, a soaking time of 62 min, a drying temperature of 60℃, and a time of 162 min. The SBRA manufactured under these optimal conditions exhibited a lower odor intensity compared to the unsoaked and undried control, suggesting that the fish odor of S-BRA has been improved. The moisture content related to the texture of the S-BRA was lower than that of the control, and the hardness was higher. Therefore, the S-BRA developed in this study will appeal to people of all ages, especially the younger generation; their consumption is expected to increase.

      • 여수국가산업단지 인근 지역 대기오염물질 농도에 영향을 미치는 요인분석

        김민영,변정훈,이영훈,이건영,한지은,이예림,임지현,장봉기 순천향대학교 기초과학연구소 2022 순천향자연과학연구 논문집 Vol.28 No.1,2

        Eight monitoring stations in the Yeosu National Industrial Complex will determine the concentration of air pollutants measured every hour in 2019, analyze what factors affect them, and how they correlate with the air pollutant measurements. Six air pollutants (SO2, NO2, O3, CO, PM-10 and PM-2.5) measured at eight monitoring stations around Yeosu National Industrial Complex (Seogang-dong, Wolnae-dong, Munsu-dong, Yeocheon-dong, Deokchung-dong, Hwayang-myeon, Yulchon-myeon, Samil-dong) the measurement data for each hour of the year were downloaded to analyze the concentration by weather condition, time zone, season, separation distance from Yeosu Industrial Complex, and separation distance from Gwangyang Industrial Complex. SO2, NO2, and CO concentrations were significantly higher in winter, significantly lower in summer, and O3, PM-10, and PM-2.5 concentrations were significantly higher in spring. SO2, CO, PM-10, and PM-2.5 concentrations were significantly higher between 10 a.m. and 12 p.m., NO2 concentrations were significantly higher between 7 a.m. and 9 a.m., and O3 concentrations were significantly higher between 13 p.m. and 15 p.m.(p<0.001). The concentration of air pollutants (SO2, NO2, CO, PM-10, PM-2.5) excluding O3 was found to have a negative (-) correlation with weather condition, and in the case of O3, it was found to have a positive (+) correlation with PM-10, PM-2.5, temperature and wind speed. It was confirmed that the concentration of air pollutants emitted from the Yeosu National Industrial Complex differs depending on the season, time and distance to the industrial complex. This study aims to establish measures to minimize health damage to residents living relatively close to the industrial complex and contribute to the establishment of management and response measures according to the properties of substances to reduce the concentration of air pollutants in the future.

      • ‘숙명역사관’뮤지엄 아이덴티티 개선을 위한 마케팅, 디자인 전략 수립 -특별 기획전, 홍보, 기프트 샵을 중심으로-

        박민지,박한빛,서예원,이진민,장미정,이성애 숙명여자대학교 산업디자인연구소 2017 숙명디자인학 연구 Vol.24 No.-

        본 연구는 디자인과 마케팅이 이분법적으로 나누어질 수 없음을 인식하고, 디자인과 마케팅을 융합하여 스페이스 디자인 마케팅을 통한 뮤지엄아이덴티티를 구축하는 일련의 프로세스를 제안하는데 목적이 있다. 본 연구는 2017년 3월~6월 총 15주간 숙명여자대학교 환경디자인과 ‘브랜드·스페이스·마케팅’수업에 서 진행된 결과물로서 작업물을 정리하였다. 본 연구의 범위는 4개(物, 事, 人, 場)의 주제 중, 장소(場)를 중심으로 ‘숙명역사관’의 그래픽, 제품, 공간을 개발하는 브랜드 매뉴얼과 연관하여 한정한다. 이에 본 연구는 ‘숙명역사관’이 가지고 있는 역사적 컨텐츠와 가치를 통해 현재 상황과 문제점을 분석하였다. 그 결과 ‘숙명역사관’의 다양한 마케팅 전략을 제시하고 이에 따른 디자인 전략과 해결 방안을 통해 디자인과 마케팅의 융합을 꾀하였다. 아울러 SWOT 분석을 통해 로고, 명함부터 새로 기획하는 숙명역사관 기프트샵, 인테리어디자인, 디스플레이, 공간연출과 그 안의 제품디자인에 이르기까지 일관성과 통일성을 추구했다. 끝으로 본 연구는 뮤지엄아이덴티티 구축을 위한 창의적 디자인 프로세스를 고찰하며, 이를 바탕으로 개발 매뉴얼을 총체적으로 정리함에 있어서 뮤지엄 브랜딩의 기초 자료로 활용될 것으로 기대된다.

      • 마임 건강식품 홍삼진을 이용한 전통과 모던의 융합적 브랜드 이벤트 프로모션 산업체 연계를 통한 아트, 디자인, 공학, 마케팅 융합 디자인을 중심으로-

        길혜경,박민지,이하은,조예린,이진민,장미정,이성애 숙명여자대학교 산업디자인연구소 2017 숙명디자인학 연구 Vol.24 No.-

        본 연구는 융합 연출 디자인 이라는 목적에서 출발하여 마임 브랜드 홍삼진 제품을 다각적 측면에서 기획 및 분석하는데 목적이 있다. 이에 본 연구는 2017년 3월~ 6월 15주 동안 숙명여대 환경디자인학과<융합 캡스톤 디자인>수업을 통해 이루어졌다. 또한 본 연구는 마임브랜드 중, 건강식품을 브랜딩하고 있는 <홍삼 진>을 선택하였다. 그 결과 본 연구는 기존 이벤트 프로모션과 전시의 사회적 문제를 도출하였고, 이를 해결하기 위한 방안으로서 전통과 현대의 융합의 오감적 체험 프로모션을 주제로 선정하였다. 아울러 본 연구는 SWOT/STP 마케 팅 분석 방법과 브레인스토밍을 사용하여 아트, 디자인, ICT, Marketing의 융합 브랜드를 구축하였다.끝으로 본 연구는 향후 마케팅을 기반한 융합 브랜드 개발에 있어 기초 자료로 활용될 수 있을 것이라 기대된다.

      • 임부의 연령에 따른 보완대체요법에 관한 인식 태도 경험 비교 연구

        김연진,김지연,노경민,신혜리,유예지,이지민,장희조,정아인,최소정,강숙정,이향연,민혜영 이화여자대학교 간호과학대학 2016 이화간호학회지 Vol.- No.50

        Purpose: This study aims to test if the age of pregnant women affects the perception, experience, and attitude towards complementary alternative therapy (CAT), by investigating the perception, experience, and attitude of pregnant women under the age of 35, and above 35 (Advanced Maternal Age). The study will 1) find the general characteristics of pregnant women under and over the age of 35 2) compare the perception, behavior, and experience of pregnant women under and over the age of 35, and 3) find the comparison of the perception, behavior, and experience according to the general characteristics of pregnant women under and over the age of 35. Method: The subjects of this study are composed of 44 women under the age of 35 and 44 women above the age of 35, totaling 88 pregnant women visiting midwiferies, obstetrics and gynecology, and baby fairs in Seoul and Gyeong-Gi area. Data for this study was collected from November 28, 2015 to January 6, 2016 for 40 days. The collected data analyzed mean, standard deviation, t test, ANOVA, and chi-square by using SPSS 23.0. Result Results show that there is a significant difference in the perception, attitude, and experience of the two-sample groups in the use of CAT. The question of “what is most necessary when applying CAT in a hospital clinical environment” for the perception criteria came out with the results of t=9.980, p<.05. For the attitude, results showed that the answers of pregnant women under the age of 35 displayed a more positive attitude towards CAT. (t=2.421, p<.05) Lastly, in the experience section, pregnant women under the age of 35 showed more CAT use than the other sample group. Conclusion Results have shown that there is a difference in the perception, behavior, and experience between the two sample groups. Therefore further research on the efficacy and the adverse effects of CAT needs to be done.

      • KCI등재

        갓(Brassica juncea)을 첨가한 간장 피조개(Scapharca broughtonii)장의 개발 및 관능특성

        강상인 ( Sang In Kang ),김예진 ( Ye Jin Kim ),이지운 ( Ji Un Lee ),박시형 ( Si Hyeong Park ),최관수 ( Kwan Su Choi ),송호수 ( Ho-su Song ),최정미 ( Jung-mi Choi ),허민수 ( Min Soo Heu ),이정석 ( Jung Suck Lee ) 한국수산과학회 2021 한국수산과학회지 Vol.54 No.6

        The home meal replacement (HMR) market has attracted significant attention due to COVID-19 pandemic and products that utilize the combination of different processed ingredients are now being developed. In this study, Broughton’s ribbed ark Scapharca broughtonii was soaked in seasoned soy sauce with the incorporation of mustard leaf Brassica juncea (M-BRA), which is known to have a unique texture as well as excellent functional properties such as antioxidation, to develop a regional specialty product. The optimal conditions for manufacturing M-BRA from the seasoned soy sauce (the sauce to be added [X<sub>1</sub>] and the soaking time [X<sub>2</sub>]), were examined using response surface methodology (RSM) to analyze the significance of the salinity (Y<sub>1</sub>), amino-N content (Y<sub>2</sub>), and overall acceptance (Y<sub>3</sub>). The coefficient of determination (R<sup>2</sup>) between X<sub>1</sub>-X<sub>2</sub> and Y<sub>1</sub>-Y<sub>3</sub> were close to 1, thereby confirming the suitability of the RSM model. The optimal conditions were seasoned soy sauce addition of 140% and soaking time of 156 min. The M-BRA manufactured under these conditions exhibited superior overall acceptance compared to seasoned commercial soy sauce, which was used as a control. We expect that the market for M-BRA manufactured by combining marine and agricultural materials will expand owing to superior overall acceptance compared with commercial products.

      • 원발성 담즙성 간경변증의 임상적 특성과 UDCA 치료반응

        김주영,김태헌,유권,한예지,최정은,김지윤,조민선 이화여자대학교 의과학연구소 2015 EMJ (Ewha medical journal) Vol.38 No.3

        Objectives: Primary biliary cirrhosis (PBC) is a chronic cholestatic liver disease that may progress to end stage liver cirrhosis. Benefits of ursodeoxycholic acid (UDCA) treatment has been investigated through large clinical studies. However, most of the studies were done in western countries and recent increase in prevalence of this relatively uncommon chronic liver disease draws attention in Korea. As early UDCA treatment effectively prevent the grave consequences of PBC progression, early diagnosis and lifelong management with UDCA is important. This study was designed to investigate the clinical features of PBC and response rates of UDCA treatments in Ewha Womans University Medical Center. Methods: Clinical data of PBC patients diagnosed between 2001 and 2014 at Ewha Womans University Medical Center were analyzed retrospectively. Results: A total of 35 patients with mean follow-up duration of 42 months were enrolled. At the diagnosis, 72.7% of the patients were asymptomatic, 5.7% had decompensated liver cirrhosis. The mean serum alkaline phosphate (ALP) level was 2.65 times upper limit of normal . UDCA was prescribed in 91.4% of the patients (n=32), among which 77.4% exhibited biochemical responses defined as serum ALP less than 2 upper limit of normal at 6 months (Mayo criteria). Conclusion: Most PBC patients were asymptomatic at the time of diagnosis and the average biochemical responses rate to UDCA treatment were ranged from 60.0% to 78.9% according to various response criteria. To elucidate the clinical features and courses of Korean PBC patients in detail, larger scale investigations and longer clinical follow up studies are warranted.

      • LC-MS/MS Based Multi-omics Approaches for Prebiotic Inulin Utilization on Faecalibacterium prausnitzii

        Ji-Hyeon PARK,Sung-Hyun JO,Jae-Seung LEE,Hyo-Jin JEON,Ji-Eun KWON,Ye-Rim KIM,Ji-Hyun BAEK,Min-Gyu KIM,Yun-Gon KIM 한국생물공학회 2021 한국생물공학회 학술대회 Vol.2021 No.10

        The human gut commensal bacteria Faecalibacterium prausnitzii is well known for its anti-inflammatory effects that improve host intestinal health. Although several studies reported that inulin, one of the well-known prebiotics, increases the abundance of F. prausnitzii in the intestine, the mechanism under this effect of inulin remains unclear. Here, we applied LC-MS/MS-based multi-omics approaches to confirm the effects of inulin on F. prausnitzii. Interestingly, the proteomic analysis revealed that the putative proteins involved in sucrose utilization of F. prausnitzii are upregulated in the presence of inulin. To investigate the function of the proteins, we cloned the target genes, and observed the ability for sucrose degradation. In addition, we demonstrated that the sucrose degradation activity in F. prausnitzii culture media is enhanced by using inulin as a carbon source compared to glucose. Taken together, this study suggests that the reduction of sucrose induced by inulin could potentially improve host health and prevent gut dysbiosis like type 2 diabetes which is associated with sucrose.

      • Pre-analytical phase errors: Experience in a clinical chemistry laboratory

        Ji Young Lee,Dong Hyeon Kim,Ye Ji Jin,Ji Yeong Kim,Min Jeong Park,Ga Young Kim,Yong Lim 한국실험동물학회 2021 한국실험동물학회 학술발표대회 논문집 Vol.2021 No.7

        Recent studies have shown that up to 70% of analytical errors reflect the pre-analytical phase. However, in the field of animal experiment, various conditions for reducing errors before analysis are lacking. There is also insufficient accumulation of empirical data on the size of errors and their results, types of errors, and resolution methods. Therefore, this study aims to investigate the effect of pre-analysis error factors found during the animal experiments, especially the hemolysis of samples, on the clinical chemistry test results, to increase the probability of new drug development succeeding and to reduce both the unnecessary expenditure and time. Among the samples requested for over approximately a year, we analyzed what percentage of samples was hemolyzed and investigated clinical chemistry test items affected by the hemolyzed sample through literature review. Also, causes and prevention methods of hemolysis, and how to handle samples after blood collection were investigated. 49.8% of requested samples from various institutes were hemolyzed. In hemolyzed samples, creatinine, total protein, AST and LD increased, and glucose, direct bilirubin and TG decreased. BUN, total cholesterol and GGT did not show a statistically significant difference. The causes of hemolysis included pulling the syringe piston too strongly, leaving the blood untended for too long, too much foam in the blood, and having water in the tube. In order to prevent hemolysis, appropriate needle with a suitable gauge for the size of the animal and blood vessel should be used for blood collection, and samples should be prepared according to the standard guidelines. This study aims to identify and improve problems with pre-analysis errors in animal experiments to prevent waste of time, probability and cost of new drug development, as well as to improve social awareness of laboratory animals. When researchers become aware of this information, and prevent hemolysis in advance, the accuracy of animal experiment results will increase, and further increase the probability of drug development to successfully reach the final launch stage.

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