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Fabrication of PAN/Pt Composite Electrode for Direct Methanol Oxidation in Aqueous Media
He, Miaomiao,Choi, Jungsik,Son, Yongkeun,Lee, Youngkwan,Yoon, Dae-Ho,Suh, Su-Jeong TaylorFrancis 2007 Molecular Crystals and Liquid Crystals Vol.464 No.1
<P> This study was focused on the preparation and characterization of conducting polymer and metal composite, PAN/Pt, electrodes showing catalytic activity in acidic aqueous media. Electropolymerization deposited PAN thin film on ITO and this film was used as a Pt matrix. The polyaniline (PAN) matrix could adopt Pt particles catalysts into polymer itself visa either way of spontaneous reaction between PAN and PtCl62- or electrochemical reduction of the Pt (IV). Both procedures ended up with the formation of PAN/Pt composites. In-situ spectroelectrochemistry was used to investigate the composite formation processes. These composite electrodes were identified with SEM and EDAX. Catalytic decomposition of methanol on these electrodes was observed by using cyclic voltammetry method.</P>
Numerical Model about the Influence of Cyclic Load on the Hydraulic Conductivity of Soft Clay
Miaomiao Sun,Jiangang Yu,Zhi Ding,Shaoheng He 대한토목학회 2021 KSCE JOURNAL OF CIVIL ENGINEERING Vol.25 No.11
The hydraulic conductivity k is one of the most important engineering properties of soft clay, and it plays an important role during the whole life cycle of underwater tunnel. Therefore, it is necessary to systematically study the response of k to dynamic load. In this study, a series of seepage tests were conducted on remolded Hangzhou soft clay using dynamic triaxial seepage apparatus after cyclic loading. The results show that the hydraulic conductivitys of all samples decrease after cyclic loading, and the maximum drop of the hydraulic conductivity can reach 29.1%. Also, the hydraulic conductivity of soil samples is significantly affected by cyclic stress ratio (CSR). With the increase of CSR, the decrease range of hydraulic conductivity under cyclic loading is between 22.3% and 24.3%. The dynamic load reconstructed the microstructure of clay and made the number of large pores getting decreased and the small pores increased. This resulted in a decrease in the smaller hydraulic conductivity (k) of the specimens. Futhermore, based on the nuclear magnetic resonance (NMR) scanning on the microstructure of soil samples under cyclic loading and the microscopic pore channel theory, a prediction model for the k of soft clay is proposed. The validity of the model is verified based on test data. It is believed that the proposed model could provide some theoretical support for the design and long-term performance prediction in practical engineering issues.
Jingyu Ni,Zhihao Liu,Miaomiao Jiang,Lan Li,Jie Deng,Xiaodan Wang,Jing Su,Yan Zhu,Feng He,Jingyuan Mao,Xiumei Gao,Guanwei Fan 고려인삼학회 2022 Journal of Ginseng Research Vol.46 No.2
Background: Ginsenoside Rg3 is one of the main active ingredients in ginseng. Here, we aimed to confirm its protective effect on the heart function in transverse aortic coarctation (TAC)-induced heart failure mice and explore the potential molecular mechanisms involved. Methods: The effects of ginsenoside Rg3 on heart and mitochondrial function were investigated by treating TAC-induced heart failure in mice. The mechanism of ginsenoside Rg3 for improving heart and mitochondrial function in mice with heart failure was predicted through integrative analysis of the proteome and plasma metabolome. Glucose uptake and myocardial insulin sensitivity were evaluated using micro-positron emission tomography. The effect of ginsenoside Rg3 on myocardial insulin sensitivity was clarified by combining in vivo animal experiments and in vitro cell experiments. Results: Treatment of TAC-induced mouse models with ginsenoside Rg3 significantly improved heart function and protected mitochondrial structure and function. Fusion of metabolomics, proteomics, and targeted metabolomics data showed that Rg3 regulated the glycolysis process, and Rg3 not only regulated glucose uptake but also improve myocardial insulin resistance. The molecular mechanism of ginsenoside Rg3 regulation of glucose metabolism was determined by exploring the interaction pathways of AMPK, insulin resistance, and glucose metabolism. The effect of ginsenoside Rg3 on the promotion of glucose uptake in IR-H9c2 cells by AMPK activation was dependent on the insulin signaling pathway. Conclusions: Ginsenoside Rg3 modulates glucose metabolism and significantly ameliorates insulin resistance through activation of the AMPK pathway.
Maritime Targets Tracking in Heavy-tailed Clutter With Unknown and Time-varying Density
Liwei Shi,Yu Kuang,Miaomiao He 제어·로봇·시스템학회 2024 International Journal of Control, Automation, and Vol.22 No.4
In order to solve the problem of maritime targets tracking in heavy-tailed sea clutter with unknown and time-varying clutter density, a multi-scan clutter sparsity estimator based amplitude-aided probability hypothesis density (MCSE-APHD) method is proposed in this paper. Firstly, the proposed method eliminates the targetoriginated measurements from multi-scan cumulative measurement set and estimates the spatial distribution density of clutter online. And the estimated clutter density parameter is fed to the tracker. Secondly, the amplitude-aided likelihood function as well as the estimated clutter parameter is established to update the Gaussian mixture posterior intensity of the state using the probability hypothesis density algorithm. The simulation results verify the effectiveness of the proposed algorithm.
Wenzhu Dai,Jixiang He,Ling Zheng,Mingyu Bi,Fei Hu,Minju Chen,Heng Niu,Jingyu Yang,Ying Luo,Wenru Tang,Miaomiao Sheng 한국유방암학회 2019 Journal of breast cancer Vol.22 No.2
Purpose: Breast cancer is the most frequently diagnosed malignancy in women worldwide. MicroRNAs (miRNAs) are thought to serve as potential biomarkers in various cancers, including breast cancer. Methods: We evaluated the miRNA expression profiles in 1,083 breast cancer samples and 104 normal breast tissues from The Cancer Genome Atlas database. We used the edgeR package of R software to analyze the differentially expressed miRNAs in normal and cancer tissues, and screened survival-related miRNAs by Kaplan-Meier analysis. A receiver operating characteristic curve was generated to evaluate the accuracy of these miRNAs as molecular markers for breast cancer diagnosis. Furthermore, the functional role of these miRNAs was verified using cell experiments. Targets of candidate miRNAs were predicted using 9 online databases, and Gene Ontology (GO) functional annotation and pathway analyses were conducted using Database for Annotation, Visualization and Integrated Discovery online tool. Results: A total of 68 miRNAs showed significantly different expression patterns between the groups (p < 0.001), and 13 of these miRNAs were significantly associated with poor survival (p < 0.05). Three miRNAs with high specificity and sensitivity, namely, miR-148b-3p, miR-190b, and miR-429, were selected. In vitro experiments showed that the overexpression of these 3 miRNAs significantly promoted the proliferation and migration of MDA-MB-468 and T47D cells and reduced the apoptosis of T47D cells. GO and pathway enrichment analyses revealed that the targets of these dysregulated miRNAs were involved in many critical cancer-related biological processes and pathways. Conclusion: The miR-148b-3p, miR-190b, and miR-429 may serve as potential diagnostic and prognostic markers for breast cancer. This study demonstrated the roles of these 3 miRNAs in the initiation and progression of breast cancer.
Ming Li,Haijuan Xie,Miaomiao He,Wang Su,Yongzhi Yang,Jian Wang,Guangji Ye,Yun Zhou 한국유전학회 2020 Genes & Genomics Vol.42 No.2
Background The sugar will eventually be exported transporter (SWEET) family is a novel type of membrane-embedded sugar transporter that contains seven transmembrane helices with two MtN3/saliva domains. The SWEET family plays crucial roles in multiple processes, including carbohydrate transportation, development, environmental adaptability and host–pathogen interactions. Although SWEET genes, especially those involved in response to biotic stresses, have been extensively characterized in many plants, they have not yet been studied in potato. Objective The identification of StSWEET genes provides important candidates for further functional analysis and lays the foundation for the production of good quality and high yield potatoes through molecular breeding. Methods In this study, StSWEET genes were identified using a genome-wide search method. A comprehensive analysis of StSWEET family through bioinformatics methods, such as phylogenetic tree, gene structure and promoter prediction analysis. The expression profiles of StSWEET genes in different potato tissues and under P. infestans attack and sugar stress were studied using quantitative real-time polymerase chain reaction (qRT-PCR). Results Phylogenetic analysis classified 33 StSWEET genes into four groups containing 12, 5, 12 and 4 genes. Furthermore, the gene structures and conserved motifs found that the StSWEET genes are very conservative during evolution. The chromosomal localization pattern showed that the distribution and density of the StSWEETs on 10 potato chromosomes were uneven and basically clustered. Predictive promoter analysis indicated that StSWEET proteins are associated with cell growth, development, secondary metabolism, and response to biotic and abiotic stresses. Finally, the expression patterns of the StSWEET genes in different tissues and the induction of P. infestans and the process of the sugar stress were investigated to obtain the tissue-specific and stress-responsive candidates. Conclusion This study systematically identifies the SWEET gene family in potato at the genome-wide level, providing important candidates for further functional analysis and contributing to a better understanding of the molecular basis of development and tolerance in potato.
Rational design of porous NiCo2S4 nanotubes for hybrid supercapacitor
Wang Haiyang,Liang Miaomiao,He Zemin,Guo Zhun,Zhao Yang,Li Kexuan,Song Wenqi,Zhang Yongming,Zhang Xin,Zhao Yuzhen,Miao Zongcheng 한국물리학회 2022 Current Applied Physics Vol.35 No.-
The nanotube-consisted flower-like NiCo2S4 is successfully fabricated by a novel two-step hydrothermal technique. X-ray diffraction (XRD) identifies the spinel structure, scanning electron microscopy (SEM) and transmission electron microscopy (TEM) imply the flower-like morphology of the synthesized NiCo2S4. The electrochemical behaviors are studied by cyclic voltammetry and galvanostatic charge-discharge measurements. The NiCo2S4 nanotubes demonstrate enhanced pseudocapacitive performance of 429.5 C g− 1 at current density of 0.5 A g− 1 . The NiCo2S4//AC device delivers high energy density of 37.69 Wh kg− 1 , maximum power density of 4000.6 W kg− 1 and satisfied cycle property of 96% capacitance retention after over 7000 cycles. The results show that the NiCo2S4 nanotubes are promising electrode material for high performance supercapacitor applications.