An Imaging System for Monitoring the Feeding Behavior of Dairy Cows

( Cheng-yu Kuan ),( Yu-chi Tsai ),( Chen-yu Cheng ),( Jih-tay Hsu ),( Shih-torng Dnig ),( Ta-te Lin ) 한국농업기계학회 2018 한국농업기계학회 학술발표논문집 Vol.23 No.1

In sub-tropical countries, dairy cows tend to experience heat stress problems. This phenomenon may lead to declines in feed intake, milk production, and fertility. Under normal conditions, the dairy cows have a regular feeding and drinking time. For this reason, changes in feeding behavior can be a possible indicator to detect heat stress phenomena that can help farm owners monitor dairy cow health. In order to monitor and record the feeding behavior of dairy cows, an imaging system is proposed herein. The imaging system uses Raspberry Pi 3, as the embedded system, and a camera module to acquire images for dairy cow face detection in front of the feeding area to confirm if the dairy cow is eating. The dairy cow faces are detected through cascade-AdaBoost algorithms which can automatically select weak classifiers to form a strong classifier with fast processing speed in an embedded system. The factors affecting the performance of the dairy cow face detection algorithm have been tested and optimized. The system has been tested in a feeding area in National Taiwan University’s dairy farm, which has 25 dairy cows in total. By converting the frequency of dairy cow face detection into feeding time, the feeding behavior of grouped dairy cows can be analyzed. Furthermore, combining the temperature humidity index (THI) and feeding behavior can provide the farm owners with an index to evaluate the level heat stress of dairy cows.

BRCA1/2 mutation status in patients with metachronous breast and ovarian malignancies: clues towards the implementation of genetic counseling

Angel Chao,Yi-Hao Lin,Lan-Yan Yang,Ren-Chin Wu,Wei-Yang Chang,Pi-Yueh Chang,Shih-Cheng Chang,Chiao-Yun Lin,Huei-Jean Huang,Cheng-Tao Lin,Hung-Hsueh Chou,Kuan-Gen Huang,Wen-Ling Kuo,Ting-Chang Chang,Ch 대한부인종양학회 2020 Journal of Gynecologic Oncology Vol.31 No.3

Objective: The characteristics of patients with metachronous breast and ovarian malignancies and the pathogenic role of BRCA1/2 mutations remain poorly understood. We investigated these issues through a review of hospital records and nationwide Taiwanese registry data, followed by BRCA1/2 mutation analysis in hospital-based cases. Methods: We retrospectively retrieved consecutive clinical records of Taiwanese patients who presented with these malignancies to our hospital between 2001 and 2017. We also collected information from the Data Science Center of the Taiwan Cancer Registry (TCR) between 2007 and 2015. Next-generation sequencing and multiplex ligation-dependent probe amplification were used to identify BRCA1/2 mutations and large genomic rearrangements, respectively. When BRCA1/2 mutations were identified in index cases, pedigrees were reconstructed and genetic testing was offered to family members. Results: A total of 12,769 patients with breast cancer and 1,537 with ovarian cancer were retrieved from our hospital records. Of them, 28 had metachronous breast and ovarian malignancies. We also identified 113 cases from the TCR dataset. Eighteen hospital-based cases underwent BRCA1/2 sequencing and germline pathogenic mutations were detected in 7 patients (38.9%, 5 in BRCA1 and 2 in BRCA2). All BRCA1/2 mutation carriers had ovarian high-grade serous carcinomas. Of the 12 patients who were alive at the time of analysis, 5 were BRCA1/2 mutation carriers. All of them had family members with BRCA1/2-associated malignancies. Conclusions: Our results provide pilot evidence that BRCA1/2 mutations are common in Taiwanese patients with metachronous breast and ovarian malignancies, supporting the clinical utility of genetic counseling.

Construction of the Operating Limits Diagram for a Ship-Based Helicopter Using the Design of Experiments with Computational Intelligence Techniques

Lin Hsin-Hung,Wu Sheng-Ju,Liu Tsung-Lung,Pan Kuan-Cheng 한국항공우주학회 2021 International Journal of Aeronautical and Space Sc Vol.22 No.1

Compared with land-based helicopters, ship-based helicopters are required to land in a more challenging working environment as the airwakes generated by the wind field flowing through the superstructure of the ship changes the wind field structure. This complicates the wind field structure and affects the safety of flight control. The flight safety of the helicopter pilot can be significantly improved with prior understanding of the relevant information in the ship-based helicopter operating limits (SHOL) diagram. In previous studies, the SHOL diagram of ship-based helicopters has been obtained using numerical simulations in conjunction with a flight simulator. However, the flight simulator equipment is expensive and difficult to maintain. This study references the aforementioned studies by initially employing a numerical simulation method to obtain the flow field information of the interaction between the airwakes of the ship’s superstructure and the downwash flow of the helicopter. Then, the flight simulator is replaced by computational intelligence methods involving artificial intelligence. This significantly reduces the research cost for envelope construction. This study integrates design of experiments (DOE) and computational intelligence techniques (soft computing) to establish a recommended range for the SHOL diagram of ship-based helicopters. This study utilizes the DOE and computational intelligence techniques to construct the SHOL diagram of ship-based helicopters, provide suggestions, and serve as a reference for helicopter pilots and engineering designers to improve the safety during flight.

Credit Rating Anomaly in Taiwan Stock Market

Kuan-Cheng Ko,Shinn-Juh Lin,Hsiang-Hui Chu,Hsiao-Wei Ho 한국재무학회 2012 한국재무학회 학술대회 Vol.2012 No.09

Rational asset-pricing theory asserts that higher risk should be accompanied by higher expected return. The credit-risk puzzle, however, states a negative cross- sectional relationship between credit risk and future stock returns (Dichev, 1998; Grin and Lemmon, 2002; Campbell et al., 2008; Avramov et al., 2009). This pa- per examines the credit-risk puzzle using an independent dataset from Taiwan's stock market. We document the existence of the credit-risk premium in both portfolios and individual stocks, and demonstrate that it can not be explained by well-known asset-pricing models which include the CAPM, Fama and French's (1993) three-factor model, and Liu's (2006) liquidity-augmented CAPM. Unlike the evidence in the U.S. market, rating downgrades only have limited impact on stock returns in Taiwan. Further analysis indicates that credit rating serves as a better proxy for distress risk, and is thus priced in Taiwan's stock market.

Application of Recurrence Plots and VGG Deep Learning Model to the Study of Condition Monitoring of Robotic Grinding

Kuan‑Jung Chung,Cheng‑Han Dai,Tung‑Chun Chiang,June‑Jia Xie,Ming-Tzer Lin 한국정밀공학회 2023 International Journal of Precision Engineering and Vol.24 No.9

This study adopted AI to identify the normal and abnormal vibration signals generated during robotic grinding. This study classified four fundamental factors affecting grinding into three levels to obtain a widely used result and designed an L9(34)orthogonal array for the grinding experiment. During experimentation, part of the grinding wheels was added weight to produce abnormal vibration signals, which an accelerometer would measure. The study transformed the collected vibration signals into recurrence plots and conducted model training with VGG16 CNN architecture. Finally, this study tested a model with 89.6% training accuracy. The results showed the model could identify whether the recurrence plots stand for normal or abnormal vibrations, with an accuracy of 85%. This means it could predict normal and abnormal grinding conditions and help avoid problems caused by abnormal vibrations.

The Antiproliferation Activity of Ganoderma formosanum Extracts on Prostate Cancer Cells

( Cheng-yen Chiang ),( Kai-di Hsu ),( Yen-yi Lin ),( Chang-wei Hsieh ),( Jui-ming Liu ),( Tze-ying Lu ),( Kuan-chen Cheng ) 한국균학회 2020 Mycobiology Vol.48 No.3

Androgen-independent prostate cancer accounts for mortality in the world. In this study, various extracts of a medical fungus dubbed Ganoderma formosanum were screened for inhibition of DU145 cells, an androgen-independent prostate cancer cell line. Results demonstrated that both hexane (GF-EH) and butanol (GF-EB) fraction of G. formosanum ethanol extract inhibited DU145 cell viability in a dose-dependent manner. GF-EH induced cell-cycle arrest in G1 phase of DU145 cells via downregulation of cyclin E2 protein expression. In addition, GF-EB triggered extrinsic apoptosis of DU145 cells by activating caspase 3 gene expression resulting in programed cell death. Above all, both GF-EH and GF-EB show lower toxicity to normal human fibroblast cell line compared to DU145 cell, implying that they possess specific drug action on cancer cells. This study provides a molecular basis of G. formosanum extract as a potential ingredient for treatment of androgen-independent prostate cancer.

Credit Rating Anomaly in the Taiwan Stock Market

Kuan-Cheng Ko,Hsiang-Hui Chu,Shinn-Juh Lin,Hsiao-Wei Ho 한국증권학회 2013 Asia-Pacific Journal of Financial Studies Vol.42 No.3

Rational asset-pricing theory asserts that higher risk should be accompanied by higher expected return. The credit risk puzzle, however, states a negative cross-sectional relationship between credit risk and future stock returns (Journal of Finance, 53, 1998, 1131; Journal of Finance, 57, 2002, 2317; Journal of Finance, 63, 2008, 2899; Journal of Financial Markets, 12, 2009, 469). This paper examines the credit risk puzzle using an independent dataset from Taiwan’s stock market. We document a significantly positive premium between highest- and lowest-rated stocks in both portfolios and individual stocks, and demonstrate that it cannot be explained by well-known asset-pricing models, including the CAPM, Journal of Financial Economics, 33, 1993, 3 three-factor model, and Journal of Financial Economics 82, 2006, 631 liquidity-augmented CAPM. Unlike the evidence collected from the US market, rating downgrades only have limited impact on the cross-sectional variation of stock returns in Taiwan. Further analysis indicates that credit rating serves as a better proxy for distress risk, and is thus priced in Taiwan’s stock market.

Slide Session : OS-CAD-06 ; Cardiology : Erythrocytosis Increased One-Year Mortality in Patients with St-Segment Elevation Myocardial Infarction Un-dergoing Primary Percutaneous Coronary Intervention

( Cheng Wei Liu ),( Yi Ching Lin ),( Chung Ming Tu ),( Pen Chih Liao ),( Kuan Change Chen ),( Yen Wen Wu ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

Background: Anemia is associated with poor prognosis in patients with ST-segment elevation myocardial infarction(STEMI). However, it is unclear that erythrocytosis has protective effect in these populations. Hence, we conducted a retrospective cohort study to examine the relationship between erythrocytosis and mortality in patients with STEMI undergoing primary percutaneous coronary intervention (PCI ). Materials and Methods: We screened 1,156 consecutive patients with STEMI undergoing primary PCI in a single center during Feb 2007 and January 2012. There were 201 missing data for door-to-balloon time and 4 missing data for hemoglobin. Of 951 analyzable patients, they were divided into anemia (Hemoglobin<13.0mg/dl in men or <12.0mg/dl in women), normal hemoglobin, and erythrocytosis (hemoglobin =16.0mg/dl in men or =15.0mg/dl in women) groups. The study end point was one-year mortality. Results: There were 148, 535, and 268 patients in anemia, normal hemoglobin, and erythrocytosis groups, respectively. Patients in the anemia group were older and had lower body mass index than other two groups. There was more female, smokers, hypertension, and diabetes in the anemia group. One-year mortality rates were 16.2%, 6.5%, 2.6% (P<0.001) respectively. In univariate proportional hazards regression analysis, age, hemoglobin, total cholesterol, statin use, glycoprotein llb/llla inhibitor use, and TIMI risk score were associated with 1-year mortality in three groups. After adjustment for potential confounders, hemoglobin levels remained an independent predictor of one-year mortality in both anemia (hazard ratio 0.697, 95% CI 0.528-0.960) and erythrocytosis group (hazard ratio 3.129, 95% CI 1.1.474-6.642). Conclusions: Patients with STEMI and anemia had the worst outcomes than normal hemoglobin and erythrocytosis groups. Expectedly, hemoglobin had the protective effect on prognosis in anemia group. However, a hemoglobin level was an independent risk factor of one-year mortality in those with erythrocytosis.

Predicting the surgical reparability of large-to-massive rotator cuff tears by B-mode ultrasonography: a cross-sectional study

Po-Cheng Chen,Kuan-Ting Wu,Yi-Cun Chen,Yu-Chi Huang,Ching-Di Chang,Wei-Che Lin,Wen-Yi Chou 대한초음파의학회 2022 ULTRASONOGRAPHY Vol.41 No.1

Purpose: This study aimed to compare the ability of B-mode ultrasonography and magnetic resonance imaging (MRI) to predict the repairability of large-to-massive rotator cuff tears (RCTs). Methods: This cross-sectional study included participants with large-to-massive RCTs who underwent arthroscopic repair. B-mode ultrasonography and MRI were conducted prior to arthroscopic repair. B-mode ultrasonography was used to evaluate the echogenicity of the rotator cuff muscle using the Heckmatt scale. Intra-rater and inter-rater reliabilities were examined for two independent physicians. MRI was used to evaluate the degrees of tendon retraction, fatty infiltration of rotator cuff muscles, and muscle atrophy. Finally, two experienced orthopedic surgeons performed surgery and decided whether the torn stump could be completely repaired intraoperatively. Results: Fifty participants were included, and 32 complete repairs and 18 partial repairs were performed. B-mode ultrasonography showed good intra-rater reliability and inter-rater reliability for assessment of the muscle echogenicity of the supraspinatus and infraspinatus muscles. The correlation coefficients between B-mode ultrasound findings and MRI findings showed medium to large effect sizes (r=0.4-0.8). The Goutallier classification of the infraspinatus muscles was the MRI predictor with the best discriminative power for surgical reparability (area under the curve [AUC], 0.89; 95% confidence interval [CI], 0.81 to 0.98), while the Heckmatt scale for infraspinatus muscles was the most accurate ultrasound predictor (AUC, 0.85; 95% CI, 0.74 to 0.96). No significant differences in AUCs among the MRI and ultrasound predictors were found. Conclusion: B-mode ultrasonography was a reliable examination tool and had a similar ability to predict surgical reparability to that of MRI among patients with large-to-massive RCTs. Purpose: This study aimed to compare the ability of B-mode ultrasonography and magnetic resonance imaging (MRI) to predict the repairability of large-to-massive rotator cuff tears (RCTs).Methods: This cross-sectional study included participants with large-to-massive RCTs who underwent arthroscopic repair. B-mode ultrasonography and MRI were conducted prior to arthroscopic repair. B-mode ultrasonography was used to evaluate the echogenicity of the rotator cuff muscle using the Heckmatt scale. Intra-rater and inter-rater reliabilities were examined for two independent physicians. MRI was used to evaluate the degrees of tendon retraction, fatty infiltration of rotator cuff muscles, and muscle atrophy. Finally, two experienced orthopedic surgeons performed surgery and decided whether the torn stump could be completely repaired intraoperatively.Results: Fifty participants were included, and 32 complete repairs and 18 partial repairs were performed. B-mode ultrasonography showed good intra-rater reliability and inter-rater reliability for assessment of the muscle echogenicity of the supraspinatus and infraspinatus muscles. The correlation coefficients between B-mode ultrasound findings and MRI findings showed medium to large effect sizes (r=0.4-0.8). The Goutallier classification of the infraspinatus muscles was the MRI predictor with the best discriminative power for surgical reparability (area under the curve [AUC], 0.89; 95% confidence interval [CI], 0.81 to 0.98), while the Heckmatt scale for infraspinatus muscles was the most accurate ultrasound predictor (AUC, 0.85; 95% CI, 0.74 to 0.96). No significant differences in AUCs among the MRI and ultrasound predictors were found.Conclusion: B-mode ultrasonography was a reliable examination tool and had a similar ability to predict surgical reparability to that of MRI among patients with large-to-massive RCTs.

Novel Deadlock Control for Smartphone Manufacturing Systems Using Petri Nets

Yi-Nan Lin,Sheng-Kuan Wang,Gwo-Jen Chiou,Cheng-Ying Yang,Victor R. L. Shen,Tony Tong-Ying Juang,Ting-Jui Huang 제어·로봇·시스템학회 2022 International Journal of Control, Automation, and Vol.20 No.3

Currently, the marketing strategy in the manufacturing industry is becoming more and more competitive. Thus, the production efficiency becomes the main developing trend, which many people are now pursuing. However, the automatic production might cause resource conflicts and system deadlocks. In this study, Petri net models and analysis were used to effectively avoid deadlocks and to achieve the goal of lean production. The iPhone XS device developed by Apple is now a popular product. Consequently, this paper aims to describe its manufacturing system by using Petri net models. Meanwhile, the siphon property of Petri nets can be used to detect the deadlock in the manufacturing processes and to avoid it from occurring. Two simulation software tools, WoPeD and PIPE, were applied to conduct the experiments. The experimental results have indicated that our proposed approach is more feasible and acceptable than other existing ones.